BE1014938A4 - Sequence d'adn codant pour une proteine de canal sodique, sa production et son utilisation. - Google Patents

Sequence d'adn codant pour une proteine de canal sodique, sa production et son utilisation. Download PDF

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Publication number
BE1014938A4
BE1014938A4 BE9800843A BE9800843A BE1014938A4 BE 1014938 A4 BE1014938 A4 BE 1014938A4 BE 9800843 A BE9800843 A BE 9800843A BE 9800843 A BE9800843 A BE 9800843A BE 1014938 A4 BE1014938 A4 BE 1014938A4
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BE
Belgium
Prior art keywords
leu
phe
val
ser
ile
Prior art date
Application number
BE9800843A
Other languages
English (en)
French (fr)
Inventor
Paul Shartzer Dietrich
Reena Khare
Linda Marie Fish
Douglas Kenneth Rabert
Lakshmi Sangameswaran
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of BE1014938A4 publication Critical patent/BE1014938A4/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE9800843A 1997-11-20 1998-11-20 Sequence d'adn codant pour une proteine de canal sodique, sa production et son utilisation. BE1014938A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6622597P 1997-11-20 1997-11-20

Publications (1)

Publication Number Publication Date
BE1014938A4 true BE1014938A4 (fr) 2004-07-06

Family

ID=22068111

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9800843A BE1014938A4 (fr) 1997-11-20 1998-11-20 Sequence d'adn codant pour une proteine de canal sodique, sa production et son utilisation.

Country Status (13)

Country Link
JP (1) JPH11235186A (de)
AT (1) AT410672B (de)
AU (1) AU710551B2 (de)
BE (1) BE1014938A4 (de)
CA (1) CA2251262C (de)
CH (1) CH693031A5 (de)
DE (1) DE19853233C2 (de)
FR (1) FR2771103A1 (de)
GB (1) GB2332906B (de)
IE (1) IE980956A1 (de)
IT (1) IT1306213B1 (de)
NL (1) NL1010602C2 (de)
SE (1) SE9803962L (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038889A2 (en) * 1998-01-29 1999-08-05 Yale University Modulation of sodium channels in dorsal root ganglia
US6573067B1 (en) 1998-01-29 2003-06-03 Yale University Nucleic acid encoding sodium channels in dorsal root ganglia
AU2001239860A1 (en) * 2000-02-25 2001-09-03 Incyte Genomics, Inc. Transporters and ion channels
DE10022092A1 (de) 2000-05-08 2001-11-15 Aventis Behring Gmbh Stabilisiertes Protein-Präparat und Verfahren zu seiner Herstellung
WO2001092304A2 (en) * 2000-05-26 2001-12-06 Incyte Genomics, Inc. Transporters and ion channels
AU2001273888A1 (en) * 2000-07-05 2002-01-14 Neurosearch A/S New sodium channel (rnav1.5a) and use thereof
WO2002012340A2 (en) * 2000-08-03 2002-02-14 Incyte Genomics, Inc. Transporters and ion channels
AU2003215015A1 (en) * 2002-03-20 2003-10-08 Transmolecular, Inc. Recombinant expression vectors for functional nav1.9 sodium channels

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380836A (en) * 1989-02-13 1995-01-10 Arch Development Corporation Nucleic acid encoding sodium channel protein
US6110672A (en) * 1994-11-02 2000-08-29 Research Foundation Of State University Of New York, The Suny At Stony Brook Peripheral nervous system specific sodium channels, DNA encoding therefor, crystallization, X-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DIB-HAJJ S D ET AL: "NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 95, July 1998 (1998-07-01), pages 8963 - 8968, XP002110597, ISSN: 0027-8424 *
HEINEMANN S H ET AL: "Molecular basis for pharmacological differences between brain and cardiac sodium channels.", PFLUGERS ARCHIV: EUROPEAN JOURNAL OF PHYSIOLOGY. GERMANY OCT 1992, vol. 422, no. 1, October 1992 (1992-10-01), pages 90 - 92, XP008024573, ISSN: 0031-6768 *
KAYANO T ET AL: "Primary structure of rat brain sodium channel III deduced from the cDNA sequence.", FEBS LETTERS. NETHERLANDS 8 FEB 1988, vol. 228, no. 1, 8 February 1988 (1988-02-08), pages 187 - 194, XP002261550, ISSN: 0014-5793 *
NODA M ET AL: "EXISTENCE OF DISTINCT SODIUM CHANNEL MESSENGER RNA IN RAT BRAIN", NATURE, MACMILLAN MAGAZINES, US, vol. 320, no. 6058, 1986, pages 188 - 192, XP002146643, ISSN: 0028-0836 *
TRIMMER J S ET AL: "Primary structure and functional expression of a mammalian skeletal muscle sodium channel.", NEURON. UNITED STATES JUL 1989, vol. 3, no. 1, July 1989 (1989-07-01), pages 33 - 49, XP008024538, ISSN: 0896-6273 *

Also Published As

Publication number Publication date
DE19853233A1 (de) 1999-07-29
NL1010602C2 (nl) 2004-02-13
ATA194298A (de) 2002-11-15
JPH11235186A (ja) 1999-08-31
SE9803962D0 (sv) 1998-11-19
ITMI982507A1 (it) 1999-05-20
IE980956A1 (en) 2000-11-01
FR2771103A1 (fr) 1999-05-21
GB2332906A8 (en) 1999-07-19
GB2332906B (en) 2002-11-20
IT1306213B1 (it) 2001-05-30
CH693031A5 (de) 2003-01-31
DE19853233C2 (de) 2000-05-04
GB9825378D0 (en) 1999-01-13
CA2251262C (en) 2003-03-25
CA2251262A1 (en) 1999-05-20
AU9327298A (en) 1999-06-10
NL1010602A1 (nl) 1999-05-25
AT410672B (de) 2003-06-25
AU710551B2 (en) 1999-09-23
SE9803962L (sv) 1999-05-21
GB2332906A (en) 1999-07-07

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BE1014938A4 (fr) Sequence d'adn codant pour une proteine de canal sodique, sa production et son utilisation.
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RE Patent lapsed

Effective date: 20031130