CA1148157A - Hydroxyamino-eburnane derivatives and a process for the preparation thereof - Google Patents
Hydroxyamino-eburnane derivatives and a process for the preparation thereofInfo
- Publication number
- CA1148157A CA1148157A CA000353141A CA353141A CA1148157A CA 1148157 A CA1148157 A CA 1148157A CA 000353141 A CA000353141 A CA 000353141A CA 353141 A CA353141 A CA 353141A CA 1148157 A CA1148157 A CA 1148157A
- Authority
- CA
- Canada
- Prior art keywords
- ethyl
- process according
- indolo
- acid
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000424715A CA1195978A (en) | 1979-05-31 | 1983-03-28 | Hydroxyamino-eburnane derivatives and a process for the preparation thereof |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI-713 | 1979-05-31 | ||
| HU79RI713A HU181495B (en) | 1979-05-31 | 1979-05-31 | Process for producing hydroxy-imino-eburnane derivatives |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000424715A Division CA1195978A (en) | 1979-05-31 | 1983-03-28 | Hydroxyamino-eburnane derivatives and a process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1148157A true CA1148157A (en) | 1983-06-14 |
Family
ID=11001097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000353141A Expired CA1148157A (en) | 1979-05-31 | 1980-05-30 | Hydroxyamino-eburnane derivatives and a process for the preparation thereof |
Country Status (26)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446139A (en) * | 1979-05-31 | 1984-05-01 | Richter Gedeon Vegyeszeti Gyar R.T. | Hexahydroindoloquinolizinium and octahydroindoloquinolizine esters, and method of increasing blood flow in an animal with hydroxyamino-eburnane derivatives |
| HU183207B (en) * | 1980-09-10 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for preparing apovincaminic acid esters |
| HU183234B (en) * | 1980-10-17 | 1984-04-28 | Richter Gedeon Vegyeszet | Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan |
| HU182411B (en) * | 1981-11-03 | 1984-01-30 | Richter Gedeon Vegyeszet | Process for preparing eburnamonine derivatives |
| HU186891B (en) * | 1981-06-12 | 1985-10-28 | Richter Gedeon Vegyeszet | Process for producing esters of apovincaminic acid |
| HU182380B (en) * | 1981-09-30 | 1983-12-28 | Richter Gedeon Vegyeszet | Process for producing esters of vincaminic acid |
| HU191403B (en) * | 1984-04-02 | 1987-02-27 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing new, raceme and optically active 14-hydroxyimino-eburnane |
| IT1248882B (it) * | 1989-06-21 | 1995-01-30 | Richter Gedeon Vegyeszet | Derivati diesteri di ottaidro-indolo/2,3-a/chinolizina e loro sali nonche' procedimento per la loro preparazione |
| JP2851133B2 (ja) * | 1989-06-21 | 1999-01-27 | リヒター ゲデオン ベジェセティ ジャール アール．テー． | 新規ラセミ及び光学的活性オクタヒドロ―インド―ロ〔２，３―ａ〕テトラヒドロピラニル〔２，３―ｃ〕キノリジンジエステル誘導体及びその調製方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU163143B (US06534493-20030318-C00166.png) * | 1971-05-07 | 1973-06-28 | ||
| US4035370A (en) * | 1971-11-03 | 1977-07-12 | Richter Gedeon Vegyeszeti Gyar Rt. | Alkaloid esters |
| HU172068B (hu) * | 1975-06-13 | 1978-05-28 | Richter Gedeon Vegyeszet | Sposob asimmetricheskogo sinteza oktagidro-indolo/2,3-a/ khinolizidinov |
| HU174502B (hu) * | 1976-12-30 | 1980-01-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina |
| HU175527B (hu) * | 1977-03-28 | 1980-08-28 | Richter Gedeon Vegyeszet | Sposob dlja totalsinteze slozhnykh efirov apovinkaminnojj kisloty i gomologov |
| HU180514B (hu) * | 1977-05-26 | 1983-03-28 | Richter Gedeon Vegyeszet | Eljárás apovinkaminsav-észterek, illetve vinkaminsav-észterek és apovinkaminsavészterek egyidejű előállítására |
| FR2398746A1 (fr) * | 1977-07-25 | 1979-02-23 | Roussel Uclaf | Nouveaux derives d'alcaloides pentacycliques, leur procede de preparation, leur application comme medicaments, et leur application a la synthese de produits du groupe de l'eburnamonine |
-
1979
- 1979-05-31 HU HU79RI713A patent/HU181495B/hu not_active IP Right Cessation
-
1980
- 1980-05-12 IL IL60058A patent/IL60058A/xx unknown
- 1980-05-14 CH CH378580A patent/CH646970A5/de not_active IP Right Cessation
- 1980-05-14 ZA ZA00802888A patent/ZA802888B/xx unknown
- 1980-05-21 NZ NZ193795A patent/NZ193795A/xx unknown
- 1980-05-22 NL NL8002959A patent/NL8002959A/xx not_active Application Discontinuation
- 1980-05-27 GB GB8017318A patent/GB2051794B/en not_active Expired
- 1980-05-27 GR GR62053A patent/GR68469B/el unknown
- 1980-05-27 IT IT67826/80A patent/IT1147741B/it active
- 1980-05-27 GB GB8104950A patent/GB2072660B/en not_active Expired
- 1980-05-29 DD DD80232903A patent/DD201592A5/de not_active IP Right Cessation
- 1980-05-29 US US06/154,329 patent/US4345082A/en not_active Expired - Lifetime
- 1980-05-29 DK DK232080A patent/DK153149C/da not_active IP Right Cessation
- 1980-05-29 PT PT71328A patent/PT71328A/pt not_active IP Right Cessation
- 1980-05-29 DD DD80221446A patent/DD151939A5/de not_active IP Right Cessation
- 1980-05-30 FI FI801757A patent/FI801757A/fi not_active Application Discontinuation
- 1980-05-30 SU SU802927202A patent/SU927116A3/ru active
- 1980-05-30 CA CA000353141A patent/CA1148157A/en not_active Expired
- 1980-05-30 BE BE0/200842A patent/BE883576A/fr not_active IP Right Cessation
- 1980-05-30 DE DE19803020695 patent/DE3020695A1/de active Granted
- 1980-05-30 NO NO801627A patent/NO801627L/no unknown
- 1980-05-30 ES ES491992A patent/ES491992A0/es active Granted
- 1980-05-30 AT AT0287880A patent/AT373252B/de not_active IP Right Cessation
- 1980-05-30 AU AU58921/80A patent/AU540977B2/en not_active Ceased
- 1980-05-30 FR FR8012011A patent/FR2457867A1/fr active Granted
- 1980-05-30 SE SE8004079A patent/SE446003B/sv not_active IP Right Cessation
- 1980-05-30 JP JP7162580A patent/JPS55162784A/ja active Granted
- 1980-05-30 YU YU01454/80A patent/YU145480A/xx unknown
-
1981
- 1981-02-10 ES ES499286A patent/ES499286A0/es active Granted
- 1981-02-10 ES ES499287A patent/ES8202007A1/es not_active Expired
- 1981-02-10 ES ES499288A patent/ES8202008A1/es not_active Expired
- 1981-04-16 SU SU813269604A patent/SU1005663A3/ru active
- 1981-06-18 FR FR8112057A patent/FR2479828B1/fr not_active Expired
-
1985
- 1985-03-05 SE SE8501069A patent/SE461653B/sv not_active IP Right Cessation
- 1985-06-07 NO NO852308A patent/NO852308L/no unknown
Also Published As
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| DE2836449C2 (US06534493-20030318-C00166.png) | ||
| CA1195978A (en) | Hydroxyamino-eburnane derivatives and a process for the preparation thereof | |
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| US4446139A (en) | Hexahydroindoloquinolizinium and octahydroindoloquinolizine esters, and method of increasing blood flow in an animal with hydroxyamino-eburnane derivatives | |
| EP0180833B1 (de) | 4-Oxo-pyrido[2,3]pyrimidin-Derivate, Verfahren zur deren Herstellung und diese ethaltende Arzneimittel | |
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| DE2805977A1 (de) | Neue ergopeptidalkaloide, ihre herstellung und verwendung | |
| US2924600A (en) | Certificate of correction |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |