CA1057283A - 3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido) ceph-3-em-4-carboxylic acid - Google Patents

3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido) ceph-3-em-4-carboxylic acid

Info

Publication number
CA1057283A
CA1057283A CA207,441A CA207441A CA1057283A CA 1057283 A CA1057283 A CA 1057283A CA 207441 A CA207441 A CA 207441A CA 1057283 A CA1057283 A CA 1057283A
Authority
CA
Canada
Prior art keywords
compound
formula
acid
carbamoyloxymethyl
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA207,441A
Other languages
English (en)
French (fr)
Other versions
CA207441S (en
Inventor
Martin C. Cook
Gordon I. Gregory
Janice Bradshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10410683&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA1057283(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to CA293,802A priority Critical patent/CA1048016A/en
Application granted granted Critical
Publication of CA1057283A publication Critical patent/CA1057283A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA207,441A 1973-08-21 1974-08-20 3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido) ceph-3-em-4-carboxylic acid Expired CA1057283A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA293,802A CA1048016A (en) 1973-08-21 1977-12-23 Antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3964573A GB1453049A (en) 1973-08-21 1973-08-21 Cephalosporing antibiotics

Publications (1)

Publication Number Publication Date
CA1057283A true CA1057283A (en) 1979-06-26

Family

ID=10410683

Family Applications (1)

Application Number Title Priority Date Filing Date
CA207,441A Expired CA1057283A (en) 1973-08-21 1974-08-20 3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido) ceph-3-em-4-carboxylic acid

Country Status (32)

Country Link
JP (2) JPS562077B2 (de)
AR (2) AR212076A1 (de)
AT (1) AT340042B (de)
AU (1) AU473550B2 (de)
BE (1) BE819004R (de)
BG (2) BG23903A3 (de)
CA (1) CA1057283A (de)
CH (2) CH613975A5 (de)
CS (2) CS204988B2 (de)
CY (1) CY945A (de)
DD (1) DD114417A5 (de)
DE (2) DE2462376A1 (de)
DK (1) DK147683C (de)
ES (2) ES429388A1 (de)
FI (1) FI65623C (de)
FR (1) FR2241318B2 (de)
GB (1) GB1453049A (de)
GT (1) GT198302370A (de)
HK (1) HK17378A (de)
HU (1) HU170000B (de)
IE (1) IE39764B1 (de)
IL (1) IL45505A (de)
KE (1) KE2816A (de)
LU (2) LU88269I2 (de)
MY (1) MY7800188A (de)
NL (1) NL154741B (de)
NO (1) NO152751C (de)
PL (2) PL115805B1 (de)
RO (2) RO69607A (de)
SU (1) SU633483A3 (de)
YU (2) YU36737B (de)
ZA (1) ZA745331B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
FI771866A (de) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
FR2414509A1 (fr) * 1978-01-17 1979-08-10 Glaxo Group Ltd Procede de cristallisation de cefuroxime sodique
DE2804040C3 (de) * 1978-01-31 1981-03-19 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Cephemverbindungen
US4341777A (en) * 1979-09-10 1982-07-27 Glaxo Group Limited Cephalosporin antibiotic
IT1190734B (it) * 1982-03-11 1988-02-24 Opos Biochimica Srl Procedimento per la preparazione di cefuroxima e intermedi impiegati in tale procedimento
GB8320520D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8810394D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
WO2000053609A1 (en) * 1999-03-09 2000-09-14 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime
MXPA05005398A (es) * 2002-11-22 2006-03-09 Univ Johns Hopkins Meta para terapia de deterioro cognitivo.
WO2004050663A2 (en) * 2002-12-05 2004-06-17 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefuroxime sodium
JP2008275173A (ja) * 2008-08-04 2008-11-13 Toshiba Corp 分岐配管
EP2741750A1 (de) 2011-08-12 2014-06-18 Dhanuka Laboratories Ltd. Pharmazeutische zusammensetzung mit cefuroxim
WO2013038323A1 (en) 2011-09-13 2013-03-21 Unimark Remedies Ltd. Taste masked pharmaceutical compositions of cefuroxime axetil
KR101497420B1 (ko) 2013-07-05 2015-03-03 삼성중공업 주식회사 증발가스 저감용 액화천연가스 수송장치
CN105884799A (zh) * 2015-09-23 2016-08-24 石药集团中诺药业（石家庄）有限公司 一种新的头孢呋辛钠化合物

Also Published As

Publication number Publication date
DK147683B (da) 1984-11-12
GB1453049A (en) 1976-10-20
CS204988B2 (en) 1981-04-30
IE39764B1 (en) 1978-12-20
DK147683C (da) 1985-05-13
FI65623C (fi) 1984-06-11
CY945A (en) 1978-06-23
FR2241318A2 (de) 1975-03-21
DK443274A (de) 1975-04-28
LU88269I2 (de) 1994-02-03
AR212076A1 (es) 1978-05-15
GT198302370A (es) 1984-11-20
JPS5649388A (en) 1981-05-02
YU30781A (en) 1983-02-28
BG25801A3 (en) 1978-12-12
IL45505A (en) 1979-01-31
IE39764L (en) 1975-02-21
ES429388A1 (es) 1976-08-16
LU70765A1 (de) 1975-12-09
DE2439880B2 (de) 1979-02-22
BG23903A3 (en) 1977-11-10
RO64129A (fr) 1979-03-15
MY7800188A (en) 1978-12-31
HU170000B (de) 1977-03-28
DE2439880C3 (de) 1979-10-18
NO742986L (de) 1975-03-17
AR212156A1 (es) 1978-05-31
AU473550B2 (en) 1976-06-24
PL115805B1 (en) 1981-05-30
YU228374A (en) 1982-06-18
ZA745331B (en) 1975-10-29
BE819004R (fr) 1975-02-20
PL98962B1 (pl) 1978-06-30
NO152751C (no) 1985-11-13
YU41231B (en) 1986-12-31
FI65623B (fi) 1984-02-29
NL7411095A (nl) 1975-02-25
JPS5052083A (de) 1975-05-09
NL154741B (nl) 1977-10-17
ES437269A1 (es) 1977-01-01
HK17378A (en) 1978-04-07
KE2816A (en) 1978-02-24
ATA676374A (de) 1977-03-15
DE2462376A1 (de) 1976-11-25
FI245674A (de) 1975-02-22
IL45505A0 (en) 1974-11-29
RO69607A (ro) 1980-08-15
CH615931A5 (en) 1980-02-29
AT340042B (de) 1977-11-25
FR2241318B2 (de) 1979-08-10
CS204989B2 (en) 1981-04-30
JPS562077B2 (de) 1981-01-17
NO152751B (no) 1985-08-05
YU36737B (en) 1984-08-31
AU7253174A (en) 1976-02-26
CH613975A5 (en) 1979-10-31
DE2439880A1 (de) 1975-04-03
SU633483A3 (ru) 1978-11-15
DD114417A5 (de) 1975-08-05

Similar Documents

Publication Publication Date Title
CA1057283A (en) 3-carbamoyloxymethyl-7-(2-(fur-2-yl)-2-methoxyiminoacetamido) ceph-3-em-4-carboxylic acid
US3974153A (en) 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids
US4421912A (en) Cephalosporin derivatives
KR830000835B1 (ko) 세팔로스포린 항생제의 제조방법
US4138555A (en) (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
US4254119A (en) 3-Unsubstituted-3-cephem compounds
JPH0257074B2 (de)
US4406898A (en) Oxazole and oxadiazole cephalosporins
CS204957B2 (en) Method of producing novel 7-2-/4-thiazolyl/-2-iminoacetamido-3-/4-alkyl-5-oxo-6-hydroxy-4,5-dihydro-1,2,4-triazin-3-ylthio/methyl-3-cephemderivatives
US4315005A (en) Cephalosporin antibiotics
US4132789A (en) 7-[2-(2-Imino-4-thiazolin-4-yl)-2-sulfoacetamido]cephalosporins and antibacterial compositions containing them
US4943631A (en) Process for cephem compounds
US4179502A (en) 7[2-Hydroxyiminoacetamido]cephalosporins
US4560683A (en) Cephalosporin antibiotics
US4011215A (en) 3-Chloroalkylcarbamoyloxymethyl-7-[2-(fur-2-yl)-2-methoxyiminoacetamido]ceph-3-em-4-carboxylic acids and physiologically acceptable salts or oxides thereof
US4200746A (en) Cephalosporins
US4645769A (en) 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same
US4137406A (en) Cephalosporins having a sulfur containing functional group in the 7-position side chain
US4107440A (en) Intermediates for preparing substituted phenylglycylcephalosporins
EP0098615B1 (de) 1-Oxadethiacephalosporin und dieses enthaltendes antibakterielles Mittel
CA1064478A (en) 7-methoxycephalosporin derivatives
JPH093074A (ja) セファロスポリン化合物、その用途および中間体化合物
US4182868A (en) 7-Methoxycephalosporin derivatives
GB2165245A (en) Chemical compounds
US4497811A (en) 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same