BRPI0920679A2 - Células construídas expressando múltiplos imunomoduladores e usos das mesmas - Google Patents
Células construídas expressando múltiplos imunomoduladores e usos das mesmasInfo
- Publication number
- BRPI0920679A2 BRPI0920679A2 BRPI0920679A BRPI0920679A BRPI0920679A2 BR PI0920679 A2 BRPI0920679 A2 BR PI0920679A2 BR PI0920679 A BRPI0920679 A BR PI0920679A BR PI0920679 A BRPI0920679 A BR PI0920679A BR PI0920679 A2 BRPI0920679 A2 BR PI0920679A2
- Authority
- BR
- Brazil
- Prior art keywords
- immunomodulators
- expressing multiple
- cells constructed
- constructed expressing
- multiple immunomodulators
- Prior art date
Links
- 239000002955 immunomodulating agent Substances 0.000 title abstract 3
- 229940121354 immunomodulator Drugs 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 102000013462 Interleukin-12 Human genes 0.000 abstract 1
- 108010065805 Interleukin-12 Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000014509 gene expression Effects 0.000 abstract 1
- 210000002865 immune cell Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 229940117681 interleukin-12 Drugs 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Manufacturing & Machinery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hematology (AREA)
- Oncology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10381008P | 2008-10-08 | 2008-10-08 | |
| PCT/US2009/005510 WO2010042189A2 (en) | 2008-10-08 | 2009-10-08 | Engineered cells expressing multiple immunomodulators and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0920679A2 true BRPI0920679A2 (pt) | 2022-05-17 |
Family
ID=42101134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0920679A BRPI0920679A2 (pt) | 2008-10-08 | 2009-10-08 | Células construídas expressando múltiplos imunomoduladores e usos das mesmas |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9492482B2 (https=) |
| EP (1) | EP2356219A4 (https=) |
| JP (3) | JP2012504959A (https=) |
| KR (2) | KR101361416B1 (https=) |
| CN (1) | CN102575227A (https=) |
| AU (3) | AU2009302804B2 (https=) |
| BR (1) | BRPI0920679A2 (https=) |
| CA (1) | CA2739902A1 (https=) |
| IL (3) | IL212184A (https=) |
| MX (1) | MX340972B (https=) |
| RU (1) | RU2573912C2 (https=) |
| WO (1) | WO2010042189A2 (https=) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101666228B1 (ko) | 2007-09-28 | 2016-10-13 | 인트렉손 코포레이션 | 생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도 |
| CA2794196A1 (en) * | 2010-03-23 | 2011-09-29 | Intrexon Corporation | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
| SG10201600912SA (en) * | 2011-03-04 | 2016-03-30 | Intrexon Corp | Vectors conditionally expressing protein |
| CA3061802C (en) * | 2011-09-08 | 2022-04-05 | Intrexon Corporation | Crystalline diacylhydrazine and the use thereof |
| EP3692794A1 (en) * | 2011-09-16 | 2020-08-12 | Baylor College of Medicine | Targeting the tumor microenvironment using manipulated nkt cells |
| CA3101783C (en) * | 2011-10-11 | 2023-01-31 | Universitat Zurich Prorektorat Mnw | Combination medicament comprising il-12 and an agent for blockade of t-cell inhibitory molecules for tumour therapy |
| US11951157B2 (en) | 2011-10-11 | 2024-04-09 | Universitat Zurich | Methods of treating malignant tumour with IL-12 and anti-PD-1 antibody |
| CN102631671B (zh) * | 2012-04-05 | 2014-11-26 | 倪国颖 | 提高疫苗诱导的细胞毒性t细胞反应的治疗性疫苗 |
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