CY1119518T1 - Τροποποιημενα αντιγονα φυματιωσης - Google Patents
Τροποποιημενα αντιγονα φυματιωσηςInfo
- Publication number
- CY1119518T1 CY1119518T1 CY20161101254T CY161101254T CY1119518T1 CY 1119518 T1 CY1119518 T1 CY 1119518T1 CY 20161101254 T CY20161101254 T CY 20161101254T CY 161101254 T CY161101254 T CY 161101254T CY 1119518 T1 CY1119518 T1 CY 1119518T1
- Authority
- CY
- Cyprus
- Prior art keywords
- antigens
- modified treatment
- modified
- treatment
- medicines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Τροποποιημένες Rv3616c πρωτεΐνες και χρήση αυτών ως φάρμακα, ιδιαιτέρως για την πρόληψη επανενεργοποίησης φυματίωσης.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29871010P | 2010-01-27 | 2010-01-27 | |
PCT/EP2011/051158 WO2011092253A1 (en) | 2010-01-27 | 2011-01-27 | Modified tuberculosis antigens |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1119518T1 true CY1119518T1 (el) | 2018-03-07 |
Family
ID=44318698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20161101254T CY1119518T1 (el) | 2010-01-27 | 2016-12-06 | Τροποποιημενα αντιγονα φυματιωσης |
Country Status (24)
Country | Link |
---|---|
US (2) | US8932600B2 (el) |
EP (1) | EP2528621B1 (el) |
JP (2) | JP6010463B2 (el) |
KR (1) | KR20120129927A (el) |
CN (1) | CN102869372B (el) |
AU (1) | AU2011209399B2 (el) |
BR (1) | BR112012018669A2 (el) |
CA (1) | CA2786969C (el) |
CO (1) | CO6650338A2 (el) |
CY (1) | CY1119518T1 (el) |
DK (1) | DK2528621T3 (el) |
EA (1) | EA201290590A1 (el) |
ES (1) | ES2614266T3 (el) |
HR (1) | HRP20161608T1 (el) |
HU (1) | HUE031184T2 (el) |
LT (1) | LT2528621T (el) |
MX (1) | MX2012008790A (el) |
MY (1) | MY156697A (el) |
PL (1) | PL2528621T3 (el) |
PT (1) | PT2528621T (el) |
SG (1) | SG182573A1 (el) |
SI (1) | SI2528621T1 (el) |
UA (1) | UA110103C2 (el) |
WO (1) | WO2011092253A1 (el) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE039159T2 (hu) | 2008-07-25 | 2018-12-28 | Glaxosmithkline Biologicals Sa | Tuberkulózis Rv2386c protein, ezt tartalmazó készítmények és ezek alkalmazása |
NO2315597T3 (el) | 2008-07-25 | 2018-01-20 | ||
AU2009273130B2 (en) | 2008-07-25 | 2014-10-16 | Glaxo Group Limited | Novel compositions and methods |
MX2012008790A (es) * | 2010-01-27 | 2012-08-17 | Glaxosmithkline Biolog Sa | Antigenos de tuberculosis modificados. |
GB201116248D0 (en) | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
WO2013123579A1 (en) * | 2012-02-24 | 2013-08-29 | Mcmaster University | Adenovirus-based tuberculosis vaccine and its use |
CN103467582A (zh) * | 2012-06-08 | 2013-12-25 | 同济大学 | 结核杆菌重要抗原的高通量筛选及其在结核病诊断中的应用 |
CN105431166B (zh) | 2013-06-25 | 2020-09-18 | 国际艾滋病疫苗行动组织公司 | 结核病组合物和其使用方法 |
WO2015148960A1 (en) * | 2014-03-28 | 2015-10-01 | The Board Of Regents Of The University Of Oklahoma | Compositions comprising soluble hla/m. tuberculosis-specific ligand complexes and methods of production and use thereof |
GB201405921D0 (en) * | 2014-04-02 | 2014-05-14 | Glaxosmithkline Biolog Sa | Novel methods for inducing an immune response |
GB201513176D0 (en) * | 2015-07-27 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel methods for inducing an immune response |
CN105675863B (zh) * | 2016-02-17 | 2017-10-20 | 遵义医学院附属医院 | 一组耐多药结核病诊断标志物及其用途 |
WO2017218867A1 (en) | 2016-06-16 | 2017-12-21 | Aeras | Tuberculosis compositions and methods of treating or preventing tuberculosis |
CN106546737A (zh) * | 2016-10-24 | 2017-03-29 | 广州迪澳医疗科技有限公司 | 一种体外检测活动性结核的方法 |
GB201618432D0 (en) * | 2016-11-01 | 2016-12-14 | Matn Scient Ltd | Detection and treatment of demyelinating diseases |
BR112019011286A2 (pt) | 2016-12-07 | 2019-10-15 | Glaxosmithkline Biologicals Sa | métodos para produzir uma composição de lipossoma, para preparar uma composição de vacina e para preparar um kit de vacina. |
GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
GB201707700D0 (en) | 2017-05-12 | 2017-06-28 | Glaxosmithkline Biologicals Sa | Dried composition |
BR112019025193A2 (pt) | 2017-05-30 | 2020-06-23 | Glaxosmithkline Biologicals S.A. | Métodos de fabricação de um adjuvante lipossomal, de fabricação de um concentrado lipossomal, para a preparação de uma composição imunogênica com adjuvante e para a preparação de uma solução, adjuvante lipossomal, composição imunogênica com adjuvante, e, solução |
JP2021504424A (ja) | 2017-12-01 | 2021-02-15 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サポニン精製 |
CN109966170B (zh) * | 2018-02-13 | 2022-04-15 | 深圳高尚科美生物科技有限公司 | 包含生物大分子的柔性脂质体化妆品及其制备方法 |
EP3980044A1 (en) | 2019-06-05 | 2022-04-13 | GlaxoSmithKline Biologicals SA | Saponin purification |
EP4192429A1 (en) * | 2020-08-05 | 2023-06-14 | The Administrators of The Tulane Educational Fund | Method of detecting tb in bodily fluid samples |
Family Cites Families (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1786412A (en) * | 1929-11-20 | 1930-12-23 | American Telephone & Telegraph | Shielding arrangement |
US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
GB8508845D0 (en) | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
US5811128A (en) | 1986-10-24 | 1998-09-22 | Southern Research Institute | Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
WO1989001973A2 (en) | 1987-09-02 | 1989-03-09 | Applied Biotechnology, Inc. | Recombinant pox virus for immunization against tumor-associated antigens |
AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
US5549910A (en) | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
EP0845537A1 (en) | 1989-08-18 | 1998-06-03 | Chiron Corporation | Recombinant retroviruses delivering vector constructs to target cells |
US5725871A (en) | 1989-08-18 | 1998-03-10 | Danbiosyst Uk Limited | Drug delivery compositions comprising lysophosphoglycerolipid |
US5707644A (en) | 1989-11-04 | 1998-01-13 | Danbiosyst Uk Limited | Small particle compositions for intranasal drug delivery |
AU7258491A (en) * | 1990-02-09 | 1991-09-03 | E.I. Du Pont De Nemours And Company | Htlv envelope antigenic segment |
US5466468A (en) | 1990-04-03 | 1995-11-14 | Ciba-Geigy Corporation | Parenterally administrable liposome formulation comprising synthetic lipids |
SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
JP3218637B2 (ja) | 1990-07-26 | 2001-10-15 | 大正製薬株式会社 | 安定なリポソーム水懸濁液 |
JP2958076B2 (ja) | 1990-08-27 | 1999-10-06 | 株式会社ビタミン研究所 | 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法 |
US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
DE69229476T2 (de) | 1991-08-15 | 2000-03-16 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Ospa proteine von borrelia burgdorferi untergruppen, dafür kodierende gene sowie impfstoffe |
US5756353A (en) | 1991-12-17 | 1998-05-26 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol-and liposome-based delivery |
EP0641192B1 (en) | 1992-05-18 | 1997-07-23 | Minnesota Mining And Manufacturing Company | Transmucosal drug delivery device |
US5792451A (en) | 1994-03-02 | 1998-08-11 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
US5928647A (en) | 1993-01-11 | 1999-07-27 | Dana-Farber Cancer Institute | Inducing cytotoxic T lymphocyte responses |
US5543158A (en) | 1993-07-23 | 1996-08-06 | Massachusetts Institute Of Technology | Biodegradable injectable nanoparticles |
US5741516A (en) | 1994-06-20 | 1998-04-21 | Inex Pharmaceuticals Corporation | Sphingosomes for enhanced drug delivery |
US5551622A (en) | 1994-07-13 | 1996-09-03 | Yoon; Inbae | Surgical stapler |
AT402926B (de) | 1994-12-05 | 1997-09-25 | Hafslund Nycomed Pharma | Heterocyclische amide, verfahren zu ihrer herstellung und verwendung |
US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
US5580579A (en) | 1995-02-15 | 1996-12-03 | Nano Systems L.L.C. | Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers |
IE80468B1 (en) | 1995-04-04 | 1998-07-29 | Elan Corp Plc | Controlled release biodegradable nanoparticles containing insulin |
CA2220530A1 (en) | 1995-06-02 | 1996-12-05 | Incyte Pharmaceuticals, Inc. | Improved method for obtaining full-length cdna sequences |
US5738868A (en) | 1995-07-18 | 1998-04-14 | Lipogenics Ltd. | Liposome compositions and kits therefor |
US6592877B1 (en) | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6338852B1 (en) | 1995-09-01 | 2002-01-15 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
ES2262595T3 (es) | 1995-09-01 | 2006-12-01 | Corixa Corporation | Compuestos y metodos para la inmunoterapia y diagnostico de la tuberculosis. |
MX9801687A (es) | 1995-09-01 | 1998-11-29 | Corixa Corp | Compuestos y metodos para el diagnostico de tuberculosis. |
US6290969B1 (en) | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
EP0871747A1 (en) | 1996-01-02 | 1998-10-21 | Chiron Viagene, Inc. | Immunostimulation mediated by gene-modified dendritic cells |
CZ126699A3 (cs) | 1996-10-11 | 1999-09-15 | Corixa Corporation | Polypeptid obsahující antigenní část rozpustného antigenu M. tuberculosis nebo variantu uvedeného antigenu, molekula DNA kódující tento polypeptid, expresivní vektor, hostitelská buňka, způsoby diagnostiky infekce M. tuberculosis a diagnostické kity |
US6544522B1 (en) | 1998-12-30 | 2003-04-08 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
US6627198B2 (en) | 1997-03-13 | 2003-09-30 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis antigens and their uses |
US6350456B1 (en) | 1997-03-13 | 2002-02-26 | Corixa Corporation | Compositions and methods for the prevention and treatment of M. tuberculosis infection |
US7087713B2 (en) * | 2000-02-25 | 2006-08-08 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
US6555653B2 (en) | 1997-05-20 | 2003-04-29 | Corixa Corporation | Compounds for diagnosis of tuberculosis and methods for their use |
US6613881B1 (en) | 1997-05-20 | 2003-09-02 | Corixa Corporation | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
CZ298347B6 (cs) | 1998-02-05 | 2007-09-05 | Glaxosmithkline Biologicals S.A. | Fúzní protein z rodiny MAGE, kódová sekvence nukleové kyseliny, vektor, hostitelská bunka, vakcina a použití fúzního proteinu pro výrobu vakciny |
PL202844B1 (pl) | 1998-04-07 | 2009-07-31 | Corixa Corp | Immunogeniczny polipeptyd, polinukleotyd, polipeptyd, kompozycja farmaceutyczna, wektor ekspresji, kompozycja szczepionki, polipeptyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis, polinukleotyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis i sposób wytwarzania polipeptydu |
CA2347099C (en) | 1998-10-16 | 2014-08-05 | Smithkline Beecham Biologicals S.A. | Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof |
US7311922B1 (en) * | 1999-10-07 | 2007-12-25 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
SI1542732T1 (sl) | 2000-06-20 | 2010-01-29 | Corixa Corp Csc The United Sta | Fuzijski proteini Mycobacterium tuberculosis |
US7538206B2 (en) | 2001-02-22 | 2009-05-26 | Institut Pasteur | Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses |
WO2002072792A2 (en) * | 2001-03-13 | 2002-09-19 | Corixa Corporation | Heterologous fusion protein constructs comprising a leishmania antigen |
CN100509912C (zh) | 2002-02-14 | 2009-07-08 | 三井化学株式会社 | 聚酯制备用催化剂、用此催化剂制备聚酯树脂的方法 |
US7026465B2 (en) * | 2002-02-15 | 2006-04-11 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis |
IL165372A0 (en) * | 2002-06-11 | 2006-01-15 | Glaxosmithkline Biolog | Immunodenic compositions |
US7205259B2 (en) | 2002-07-26 | 2007-04-17 | Kimberly-Clark Worldwide, Inc. | Absorbent binder desiccant composition and articles incorporating it |
GB0323965D0 (en) * | 2003-10-13 | 2003-11-19 | Glaxosmithkline Biolog Sa | Immunogenic compositions |
JP2008527947A (ja) | 2005-01-19 | 2008-07-24 | パンデュイット・コーポレーション | 抑制コアを備えた通信チャンネル |
CA2606962A1 (en) * | 2005-04-29 | 2006-11-09 | Fusion Antibodies Limited | Assays for diagnosis of tuberculosis and uses thereof |
DK2457926T3 (da) | 2005-04-29 | 2015-01-05 | Glaxosmithkline Biolog Sa | Ny fremgangsmåde til forebyggelse eller behandling af M. tuberkulose-infektion |
ES2541771T3 (es) | 2005-05-03 | 2015-07-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Expresión de una proteína mitocondrial mediante un enfoque alotópico mejorado |
JP4468858B2 (ja) | 2005-06-01 | 2010-05-26 | オリンパスイメージング株式会社 | データ符号化装置、データ符号化方法、プログラム |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
US7296798B2 (en) | 2006-01-31 | 2007-11-20 | Matt Overfield | Gameboard, games played on board and methods of play requiring strategy and luck |
WO2008007942A1 (en) * | 2006-07-10 | 2008-01-17 | Het Nederlands Kanker Instituut | Means and methods for manipulating sequential phagolysomal-cytosolic translocation of mycobacteria, and uses thereof |
US20100183667A1 (en) | 2006-10-12 | 2010-07-22 | Glaxo Smithkline Biologicals S.A. | Vaccine Comprising an Oil in Water Emulsion Adjuvant |
EP2087128A4 (en) * | 2006-11-01 | 2009-11-04 | Immport Therapeutics Inc | COMPOSITIONS AND METHODS FOR IMMUNOMINANT ANTIGENES |
GB0622282D0 (en) * | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
PL2137210T3 (pl) * | 2007-03-02 | 2017-06-30 | Glaxosmithkline Biologicals Sa | Nowy sposób i kompozycje |
GB0716070D0 (en) * | 2007-08-17 | 2007-09-26 | Fusion Antibodies Ltd | Diagnostic method and kit |
US7670609B2 (en) * | 2007-11-27 | 2010-03-02 | Aeras Global Tb Vaccine Foundation | Recombinant BCG tuberculosis vaccine designed to elicit immune responses to Mycobacterium tuberculosis in all physiological stages of infection and disease |
FR2933552B1 (fr) | 2008-07-04 | 2014-10-10 | Centre Nat Rech Scient | Circuit d'amplification d'un signal representant une variation de resistance d'une resistance variable et capteur correspondant |
AU2009273130B2 (en) * | 2008-07-25 | 2014-10-16 | Glaxo Group Limited | Novel compositions and methods |
TR201903223T4 (tr) | 2009-04-24 | 2019-03-21 | Statens Seruminstitut | Reaktivasyonu önlemek üzere bir tüberküloz TB aşısı. |
EP2457018A4 (en) | 2009-07-21 | 2014-10-15 | Cooper Technologies Co | CONNECTING A LIGHT EMITTING DIODE MODULE (LED) TO A THERMAL DISSIPATING ASSEMBLY, LIGHT REFLECTOR, AND ELECTRIC CIRCUITS |
MX2012008790A (es) * | 2010-01-27 | 2012-08-17 | Glaxosmithkline Biolog Sa | Antigenos de tuberculosis modificados. |
US9119754B2 (en) | 2011-10-08 | 2015-09-01 | Michael Dennis | Mattress overlay system with positionally adjustable, lateral ramp-wedge bolster structure |
US9051890B2 (en) | 2013-10-28 | 2015-06-09 | Ford Global Technologies, Llc | Method for estimating charge air cooler condensation storage with an intake oxygen sensor |
US9903268B2 (en) | 2015-04-02 | 2018-02-27 | Ford Global Technologies, Llc | Internal combustion engine with two-stage supercharging capability and with exhaust-gas aftertreatment arrangement, and method for operating an internal combustion engine |
US9810514B2 (en) | 2015-09-08 | 2017-11-07 | Deufol Sunman Inc. | Ammunition carrier consumer package |
-
2011
- 2011-01-27 MX MX2012008790A patent/MX2012008790A/es active IP Right Grant
- 2011-01-27 EP EP11700859.9A patent/EP2528621B1/en active Active
- 2011-01-27 CA CA2786969A patent/CA2786969C/en active Active
- 2011-01-27 CN CN201180014803.7A patent/CN102869372B/zh active Active
- 2011-01-27 DK DK11700859.9T patent/DK2528621T3/da active
- 2011-01-27 JP JP2012550445A patent/JP6010463B2/ja active Active
- 2011-01-27 KR KR1020127022290A patent/KR20120129927A/ko not_active Application Discontinuation
- 2011-01-27 MY MYPI2012003347A patent/MY156697A/en unknown
- 2011-01-27 EA EA201290590A patent/EA201290590A1/ru unknown
- 2011-01-27 AU AU2011209399A patent/AU2011209399B2/en not_active Ceased
- 2011-01-27 WO PCT/EP2011/051158 patent/WO2011092253A1/en active Application Filing
- 2011-01-27 BR BR112012018669A patent/BR112012018669A2/pt not_active Application Discontinuation
- 2011-01-27 LT LTEP11700859.9T patent/LT2528621T/lt unknown
- 2011-01-27 HU HUE11700859A patent/HUE031184T2/en unknown
- 2011-01-27 US US13/574,816 patent/US8932600B2/en active Active
- 2011-01-27 ES ES11700859.9T patent/ES2614266T3/es active Active
- 2011-01-27 SG SG2012052767A patent/SG182573A1/en unknown
- 2011-01-27 PT PT117008599T patent/PT2528621T/pt unknown
- 2011-01-27 UA UAA201209252A patent/UA110103C2/uk unknown
- 2011-01-27 SI SI201131036A patent/SI2528621T1/sl unknown
- 2011-01-27 PL PL11700859T patent/PL2528621T3/pl unknown
-
2012
- 2012-07-25 CO CO12125075A patent/CO6650338A2/es not_active Application Discontinuation
-
2014
- 2014-12-02 US US14/557,929 patent/US9200044B2/en active Active
-
2016
- 2016-03-04 JP JP2016042444A patent/JP6503309B2/ja active Active
- 2016-12-01 HR HRP20161608TT patent/HRP20161608T1/hr unknown
- 2016-12-06 CY CY20161101254T patent/CY1119518T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2786969C (en) | 2018-07-24 |
JP6010463B2 (ja) | 2016-10-19 |
CO6650338A2 (es) | 2013-04-15 |
SG182573A1 (en) | 2012-08-30 |
KR20120129927A (ko) | 2012-11-28 |
MY156697A (en) | 2016-03-15 |
CA2786969A1 (en) | 2011-08-04 |
EA201290590A1 (ru) | 2013-03-29 |
MX2012008790A (es) | 2012-08-17 |
UA110103C2 (uk) | 2015-11-25 |
PL2528621T3 (pl) | 2017-07-31 |
AU2011209399A1 (en) | 2012-08-23 |
CN102869372A (zh) | 2013-01-09 |
EP2528621B1 (en) | 2016-09-21 |
DK2528621T3 (da) | 2017-01-02 |
WO2011092253A1 (en) | 2011-08-04 |
JP2016166193A (ja) | 2016-09-15 |
HUE031184T2 (en) | 2017-06-28 |
ES2614266T3 (es) | 2017-05-30 |
US20120294882A1 (en) | 2012-11-22 |
PT2528621T (pt) | 2016-12-20 |
JP2013517783A (ja) | 2013-05-20 |
JP6503309B2 (ja) | 2019-04-17 |
CN102869372B (zh) | 2016-01-20 |
US8932600B2 (en) | 2015-01-13 |
HRP20161608T1 (hr) | 2017-01-13 |
LT2528621T (lt) | 2016-12-12 |
SI2528621T1 (sl) | 2017-01-31 |
US9200044B2 (en) | 2015-12-01 |
US20150093414A1 (en) | 2015-04-02 |
AU2011209399B2 (en) | 2014-04-10 |
EP2528621A1 (en) | 2012-12-05 |
BR112012018669A2 (pt) | 2017-09-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1119518T1 (el) | Τροποποιημενα αντιγονα φυματιωσης | |
CY1124024T1 (el) | Νεες ctla4-ig ανοσοπροσκολλητινες | |
CY1123404T1 (el) | Αντι-girt αντισωματα | |
CY1124729T1 (el) | Φαρμακοτεχνικες μορφες του ενζαλουταμιδιου | |
CY1123739T1 (el) | Αντισωματα anti-cd38 | |
CY1121742T1 (el) | Αντισωματα s100a4 και θεραπευτικες χρησεις αυτων | |
CY1121907T1 (el) | Συζευγματα antidll3-antiσωmatoς-pbd και χρησεις αυτων | |
CY1123208T1 (el) | Κυκλικα παραγωγα εστερων βορονικου οξεος, μεθοδος για την παρασκευη και θεραπευτικες χρησεις αυτων | |
CY1122101T1 (el) | Τροποποιημενα πολυπεπτιδια ρελαξινης και χρησεις αυτων | |
CY1120646T1 (el) | Προγονικα κυτταρα μεσοδερμικης προελευσης | |
HK1212890A1 (zh) | 生物活性分子、其偶聯物及治療用途 | |
UY34254A (es) | Proteínas y péptidos modificados. | |
EA201270722A1 (ru) | Формы рифаксимина и их применение | |
UY34885A (es) | Proteínas de unión anti-mesotelina | |
EP3082797A4 (en) | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | |
EA201500172A1 (ru) | Модифицированные полипептиды фактора х и их применение | |
UY34680A (es) | Anticuerpos humanos anti-cd27, métodos, y usos | |
EA201391507A1 (ru) | АНТИТЕЛА ПРОТИВ c-Kit И ИХ ПРИМЕНЕНИЕ | |
TR201813877T4 (tr) | Spi̇nal müsküler atrofi̇ni̇n tedavi̇ edi̇lmesi̇ne yöneli̇k bi̇leşi̇kler. | |
EA201400579A1 (ru) | Антитела к il-36r | |
DK3115372T3 (da) | Målrettede terapeutiske lysosomale enzymfusionsproteiner og anvendelser deraf | |
CY1124331T1 (el) | Αυξημενη βιοδιαθεσιμοτητα δραστικης ουσιας σε θεραπεια ναλτρεξονης | |
TR201910866T4 (tr) | Kanser tedavisi için birleşik preparasyonlar. | |
EA201390955A1 (ru) | Слитый белок robo1-fc для применения в лечении гепатокарциномы | |
MA32321B1 (fr) | Pregn-4-en-21, 17 carbolactones substitués sur le noyau c, et préparations pharmaceutiques contenant ces derniers |