BRPI0807319B1 - Base de minociclina cristalina forma 1, processo para preparar base de minociclina cristalina forma i, base de minociclina cristalina forma ii, processo para preparar base de minociclina cristalina forma ii, base de minociclina cristalina forma iii e processo para preparar base de minociclina cristalina forma iii - Google Patents

Base de minociclina cristalina forma 1, processo para preparar base de minociclina cristalina forma i, base de minociclina cristalina forma ii, processo para preparar base de minociclina cristalina forma ii, base de minociclina cristalina forma iii e processo para preparar base de minociclina cristalina forma iii Download PDF

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Publication number
BRPI0807319B1
BRPI0807319B1 BRPI0807319-8A BRPI0807319A BRPI0807319B1 BR PI0807319 B1 BRPI0807319 B1 BR PI0807319B1 BR PI0807319 A BRPI0807319 A BR PI0807319A BR PI0807319 B1 BRPI0807319 B1 BR PI0807319B1
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BR
Brazil
Prior art keywords
minocycline base
crystalline minocycline
crystalline
base form
base
Prior art date
Application number
BRPI0807319-8A
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English (en)
Portuguese (pt)
Inventor
Jose Rafael Antunes
Susana Marto
William Heggie
Zita Mendes
Original Assignee
Hovione Scientia Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Scientia Limited filed Critical Hovione Scientia Limited
Priority to BR122021000846-9A priority Critical patent/BR122021000846B1/pt
Publication of BRPI0807319A2 publication Critical patent/BRPI0807319A2/pt
Publication of BRPI0807319B1 publication Critical patent/BRPI0807319B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0807319-8A 2007-02-23 2008-02-22 Base de minociclina cristalina forma 1, processo para preparar base de minociclina cristalina forma i, base de minociclina cristalina forma ii, processo para preparar base de minociclina cristalina forma ii, base de minociclina cristalina forma iii e processo para preparar base de minociclina cristalina forma iii BRPI0807319B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122021000846-9A BR122021000846B1 (pt) 2007-02-23 2008-02-22 Processo para preparar base de minociclina amorfa

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT103661A PT103661B (pt) 2007-02-23 2007-02-23 Processo de preparação de minociclina base cristalina
PT103661 2007-02-23
PCT/GB2008/000625 WO2008102161A2 (en) 2007-02-23 2008-02-22 Crystalline minocycline base and processes for its preparation

Publications (2)

Publication Number Publication Date
BRPI0807319A2 BRPI0807319A2 (pt) 2017-05-02
BRPI0807319B1 true BRPI0807319B1 (pt) 2021-08-10

Family

ID=39432804

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0807319-8A BRPI0807319B1 (pt) 2007-02-23 2008-02-22 Base de minociclina cristalina forma 1, processo para preparar base de minociclina cristalina forma i, base de minociclina cristalina forma ii, processo para preparar base de minociclina cristalina forma ii, base de minociclina cristalina forma iii e processo para preparar base de minociclina cristalina forma iii
BR122021000846-9A BR122021000846B1 (pt) 2007-02-23 2008-02-22 Processo para preparar base de minociclina amorfa

Family Applications After (1)

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BR122021000846-9A BR122021000846B1 (pt) 2007-02-23 2008-02-22 Processo para preparar base de minociclina amorfa

Country Status (20)

Country Link
US (2) US8258327B2 (enExample)
EP (1) EP2125705B1 (enExample)
JP (4) JP2010519247A (enExample)
KR (1) KR101391132B1 (enExample)
CN (1) CN101679218B (enExample)
AU (1) AU2008217619B2 (enExample)
BR (2) BRPI0807319B1 (enExample)
CA (2) CA2835788C (enExample)
DK (1) DK2125705T3 (enExample)
ES (1) ES2610434T3 (enExample)
HU (1) HUE033030T2 (enExample)
IL (1) IL200544A0 (enExample)
MX (2) MX2009008980A (enExample)
NO (1) NO20092960L (enExample)
NZ (1) NZ579626A (enExample)
PL (1) PL2125705T3 (enExample)
PT (1) PT103661B (enExample)
RU (2) RU2485095C2 (enExample)
WO (1) WO2008102161A2 (enExample)
ZA (1) ZA200906517B (enExample)

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PT108223B (pt) 2015-02-13 2018-05-08 Hovione Farm S A Novas formas polimórficas de minociclina base e processos para a sua preparação
KR20170134514A (ko) 2015-03-23 2017-12-06 바이오팜엑스 인코포레이티드 피부과 사용을 위한 약학 테트라사이클린 조성물
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WO2021191273A1 (en) 2020-03-24 2021-09-30 Hovione Scientia Limited Compositions for use in treating meibomian gland dysfunction
WO2022043457A1 (en) 2020-08-27 2022-03-03 Hovione Scientia Limited Methods and compositions for treating rosacea
CN117105812B (zh) * 2023-08-16 2025-09-26 常州市第四制药厂有限公司 一种米诺环素无菌软膏剂及制备方法

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Also Published As

Publication number Publication date
CA2722496A1 (en) 2008-08-28
WO2008102161A2 (en) 2008-08-28
EP2125705A2 (en) 2009-12-02
DK2125705T3 (en) 2017-01-16
PT103661B (pt) 2010-09-07
PL2125705T3 (pl) 2017-02-28
US20100286417A1 (en) 2010-11-11
WO2008102161A9 (en) 2008-11-13
WO2008102161A3 (en) 2009-01-08
US20130030195A1 (en) 2013-01-31
KR20100014520A (ko) 2010-02-10
AU2008217619B2 (en) 2013-01-10
US9416097B2 (en) 2016-08-16
CN101679218B (zh) 2013-10-30
BR122021000846B1 (pt) 2021-08-10
HUE033030T2 (hu) 2017-11-28
PT103661A (pt) 2008-08-25
CN101679218A (zh) 2010-03-24
IL200544A0 (en) 2010-05-17
NO20092960L (no) 2009-11-20
EP2125705B1 (en) 2016-10-12
US8258327B2 (en) 2012-09-04
RU2577331C2 (ru) 2016-03-20
RU2485095C2 (ru) 2013-06-20
NZ579626A (en) 2011-12-22
CA2722496C (en) 2014-06-10
JP2010519247A (ja) 2010-06-03
MX2009008980A (es) 2009-11-11
CA2835788A1 (en) 2008-08-28
JP2019142882A (ja) 2019-08-29
BRPI0807319A2 (pt) 2017-05-02
ZA200906517B (en) 2010-09-29
MX340539B (es) 2016-07-13
KR101391132B1 (ko) 2014-05-02
JP2017039742A (ja) 2017-02-23
JP2014169319A (ja) 2014-09-18
CA2835788C (en) 2018-03-27
AU2008217619A1 (en) 2008-08-28
RU2009135403A (ru) 2011-03-27
ES2610434T3 (es) 2017-04-27
RU2013112021A (ru) 2014-09-27

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: HOVIONE SCIENTIA LIMITED (IE)

B25A Requested transfer of rights approved

Owner name: HOVIONE SCIENTIA LIMITED (IE)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/02/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 17A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2822 DE 04-02-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.