BRPI0718504A2 - Composto ou um sal do mesmo, composição farmacêutica, uso de um composto ou um sal do mesmo farmaceuticamente aceitável, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto - Google Patents

Composto ou um sal do mesmo, composição farmacêutica, uso de um composto ou um sal do mesmo farmaceuticamente aceitável, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto Download PDF

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Publication number
BRPI0718504A2
BRPI0718504A2 BRPI0718504-9A BRPI0718504A BRPI0718504A2 BR PI0718504 A2 BRPI0718504 A2 BR PI0718504A2 BR PI0718504 A BRPI0718504 A BR PI0718504A BR PI0718504 A2 BRPI0718504 A2 BR PI0718504A2
Authority
BR
Brazil
Prior art keywords
formula
methyl
oxy
alkyl
ring
Prior art date
Application number
BRPI0718504-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Leonie Campbell
Kurt Gordon Pike
Abid Suleman
Michael James Waring
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0718504A2 publication Critical patent/BRPI0718504A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catching Or Destruction (AREA)
BRPI0718504-9A 2006-10-23 2007-10-22 Composto ou um sal do mesmo, composição farmacêutica, uso de um composto ou um sal do mesmo farmaceuticamente aceitável, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto BRPI0718504A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86249306P 2006-10-23 2006-10-23
US60/862,493 2006-10-23
US89199307P 2007-02-28 2007-02-28
US60/891,993 2007-02-28
PCT/GB2007/004018 WO2008050101A2 (en) 2006-10-23 2007-10-22 Benzoyl amino heterocyclyl compounds useful in the treatment of a disease mediated through glk

Publications (1)

Publication Number Publication Date
BRPI0718504A2 true BRPI0718504A2 (pt) 2013-12-03

Family

ID=39324963

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718504-9A BRPI0718504A2 (pt) 2006-10-23 2007-10-22 Composto ou um sal do mesmo, composição farmacêutica, uso de um composto ou um sal do mesmo farmaceuticamente aceitável, método para tratar doenças mediadas por glk, e, processo para a preparação de um composto

Country Status (18)

Country Link
US (1) US7902200B2 (US07902200-20110308-C00061.png)
EP (1) EP2086964A2 (US07902200-20110308-C00061.png)
JP (1) JP2010507640A (US07902200-20110308-C00061.png)
KR (1) KR20090068289A (US07902200-20110308-C00061.png)
AR (1) AR063499A1 (US07902200-20110308-C00061.png)
AU (1) AU2007310608A1 (US07902200-20110308-C00061.png)
BR (1) BRPI0718504A2 (US07902200-20110308-C00061.png)
CA (1) CA2667435A1 (US07902200-20110308-C00061.png)
CL (1) CL2007003033A1 (US07902200-20110308-C00061.png)
CO (1) CO6160318A2 (US07902200-20110308-C00061.png)
IL (1) IL198142A0 (US07902200-20110308-C00061.png)
MX (1) MX2009004362A (US07902200-20110308-C00061.png)
NO (1) NO20091599L (US07902200-20110308-C00061.png)
PE (1) PE20081467A1 (US07902200-20110308-C00061.png)
RU (1) RU2009114982A (US07902200-20110308-C00061.png)
TW (1) TW200825063A (US07902200-20110308-C00061.png)
UY (1) UY30660A1 (US07902200-20110308-C00061.png)
WO (1) WO2008050101A2 (US07902200-20110308-C00061.png)

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SA07280576B1 (ar) * 2006-10-26 2011-06-22 استرازينيكا ايه بي مركبات بنزويل أمينو سيكليل غير متجانسة بأعتبارها عوامل منشطة للجلوكوكيناز
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KR20090068289A (ko) 2009-06-25
CO6160318A2 (es) 2010-05-20
UY30660A1 (es) 2008-05-31
AU2007310608A1 (en) 2008-05-02
IL198142A0 (en) 2009-12-24
PE20081467A1 (es) 2008-12-07
TW200825063A (en) 2008-06-16
US20080171734A1 (en) 2008-07-17
NO20091599L (no) 2009-07-21
EP2086964A2 (en) 2009-08-12
US7902200B2 (en) 2011-03-08
RU2009114982A (ru) 2010-11-27
AR063499A1 (es) 2009-01-28
WO2008050101A3 (en) 2008-07-17
JP2010507640A (ja) 2010-03-11
MX2009004362A (es) 2009-05-05

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