BRPI0712163A2 - composto, e, agente antimicrobiano - Google Patents

composto, e, agente antimicrobiano Download PDF

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Publication number
BRPI0712163A2
BRPI0712163A2 BRPI0712163-6A BRPI0712163A BRPI0712163A2 BR PI0712163 A2 BRPI0712163 A2 BR PI0712163A2 BR PI0712163 A BRPI0712163 A BR PI0712163A BR PI0712163 A2 BRPI0712163 A2 BR PI0712163A2
Authority
BR
Brazil
Prior art keywords
compound
substituted
analog
group
bond
Prior art date
Application number
BRPI0712163-6A
Other languages
English (en)
Inventor
Kiyoto Taro
Ando Junichi
Tanaka Tadashi
Tsutsui Yasuhiro
Yokotani Mai
Noguchi Toshiya
Ushiyama Fumihito
Urabe Hiroki
Horikiri Hiromasa
Original Assignee
Toyama Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co., Ltd. filed Critical Toyama Chemical Co., Ltd.
Publication of BRPI0712163A2 publication Critical patent/BRPI0712163A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

COMPOSTO, E, AGENTE ANTIMICROBIANO. Divulga-se um composto representada pela fórmula geral: [sendo que R^1^ representa um grupo arila ou heterocíclico que pode ser substituído ou análogo; X^1^ representa um grupo C~2~-C~4~ alquileno ou análogo; X^2^, X^3^ e X^5^ representam independentemente NH, uma ligação ou análogo; X^4^ representa um grupo alquileno inferior, uma ligação ou análogo; Y^1^representa um radical hidrocarboneto alicíclico divalente que pode ser substituído ou um radical amina alicíclico divalente que pode ser substituído; e Z^1^, Z^2^, Z^3^, Z^4^, Z^5^ e Z^6^ representam independentemente um átomo de nitrogênio, um grupo representado pela fórmula: CH, ou análogo, desde que pelo menos um de Z^3^ , Z^4^ , Z^5^ e Z^6^ represente um átomo de nitrogênio] ou um sal do mesmo, que é útil como um agente antibacteriano.
BRPI0712163-6A 2006-05-26 2007-05-24 composto, e, agente antimicrobiano BRPI0712163A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006-146588 2006-05-26
JP2006146588 2006-05-26
PCT/JP2007/060606 WO2007138974A1 (ja) 2006-05-26 2007-05-24 新規な複素環化合物またはその塩ならびにその中間体

Publications (1)

Publication Number Publication Date
BRPI0712163A2 true BRPI0712163A2 (pt) 2012-03-13

Family

ID=38778494

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0712163-6A BRPI0712163A2 (pt) 2006-05-26 2007-05-24 composto, e, agente antimicrobiano

Country Status (18)

Country Link
US (2) US8211908B2 (pt)
EP (1) EP2022793B1 (pt)
JP (1) JP5171618B2 (pt)
KR (1) KR101409261B1 (pt)
CN (1) CN101454319B (pt)
AU (1) AU2007268749B2 (pt)
BR (1) BRPI0712163A2 (pt)
CA (1) CA2652501C (pt)
ES (1) ES2476423T3 (pt)
HK (1) HK1133874A1 (pt)
IL (1) IL195346A (pt)
MX (1) MX2008014908A (pt)
NO (1) NO20084701L (pt)
NZ (1) NZ573032A (pt)
RU (1) RU2434868C2 (pt)
SG (1) SG164384A1 (pt)
WO (1) WO2007138974A1 (pt)
ZA (1) ZA200809782B (pt)

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US20100144717A1 (en) * 2006-12-15 2010-06-10 Janelle Comita-Prevoir 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents
WO2008071964A1 (en) * 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
TW200831517A (en) * 2006-12-15 2008-08-01 Astrazeneca Ab Chemical compounds
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JP5620636B2 (ja) * 2007-11-26 2014-11-05 富山化学工業株式会社 新規な複素環化合物またはその塩を含有する抗菌剤
KR20100088693A (ko) * 2007-11-26 2010-08-10 토야마 케미칼 컴퍼니 리미티드 신규한 나프티리딘 유도체 1 수화물 및 그 제조법
EP2080761A1 (en) * 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
ES2398939T3 (es) 2008-02-22 2013-03-22 Actelion Pharmaceuticals Ltd. Derivados de oxazolidinona
EP2297107B1 (en) * 2008-06-03 2013-11-13 Actelion Pharmaceuticals Ltd. [4-(1-amino-ethyl) -cyclohexyl]-methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl]-methyl-amine derivatives as antibacterials
WO2010027002A1 (ja) * 2008-09-05 2010-03-11 塩野義製薬株式会社 Ｐｉ３ｋ阻害活性を有する縮環モルホリン誘導体
AU2009302007B2 (en) 2008-10-10 2015-01-15 Actelion Pharmaceuticals Ltd Oxazolidinyl antibiotics
TW201022279A (en) * 2008-11-14 2010-06-16 Astrazeneca Ab Chemical compounds
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WO2010088697A2 (en) * 2009-02-02 2010-08-05 Medtronic, Inc. Antimicrobial accessory for an implantable medical device
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
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US8911427B2 (en) 2010-12-28 2014-12-16 Medtronic, Inc. Therapeutic agent reservoir delivery system
JPWO2012108376A1 (ja) 2011-02-07 2014-07-03 第一三共株式会社 アミノ基含有ピロリジノン誘導体
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
JP2014533747A (ja) 2011-11-30 2014-12-15 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ ３，７−二置換オクタヒドロ−２Ｈ−ピリド［４，３−ｅ］［１，３］オキサジン−２−オン抗生物質
EP3733184B1 (en) * 2013-03-14 2023-08-30 Icahn School of Medicine at Mount Sinai Pyrimidine compounds for use in the treatment of cancer
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CN109678793B (zh) * 2019-01-12 2020-08-04 上海卡洛化学有限公司 一种5-氟-3-氨基吡啶的制备方法

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EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
WO2008071962A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Pteridines and pyrimidinopyridines as antibacterial agents
WO2008071964A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
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Also Published As

Publication number Publication date
AU2007268749B2 (en) 2012-07-26
CN101454319B (zh) 2012-06-27
RU2434868C2 (ru) 2011-11-27
CA2652501C (en) 2014-07-08
RU2008151754A (ru) 2010-07-10
EP2022793B1 (en) 2014-06-04
KR20090018976A (ko) 2009-02-24
JP5171618B2 (ja) 2013-03-27
HK1133874A1 (en) 2010-04-09
MX2008014908A (es) 2009-05-13
US20120226035A1 (en) 2012-09-06
WO2007138974A1 (ja) 2007-12-06
CN101454319A (zh) 2009-06-10
US8211908B2 (en) 2012-07-03
JPWO2007138974A1 (ja) 2009-10-08
IL195346A (en) 2013-02-28
ZA200809782B (en) 2010-02-24
KR101409261B1 (ko) 2014-06-18
CA2652501A1 (en) 2007-12-06
NZ573032A (en) 2010-12-24
NO20084701L (no) 2009-02-06
ES2476423T3 (es) 2014-07-14
US8367831B2 (en) 2013-02-05
EP2022793A4 (en) 2010-09-08
US20090198063A1 (en) 2009-08-06
EP2022793A1 (en) 2009-02-11
SG164384A1 (en) 2010-09-29
IL195346A0 (en) 2009-08-03
AU2007268749A1 (en) 2007-12-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]