BRPI0519424B8 - compostos, composição e uso dos ditos compostos para a preparação de um medicamento para prevenção ou tratamento de um distúrbio de proliferação celular ou infecção microbiana - Google Patents

compostos, composição e uso dos ditos compostos para a preparação de um medicamento para prevenção ou tratamento de um distúrbio de proliferação celular ou infecção microbiana

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Publication number
BRPI0519424B8
BRPI0519424B8 BRPI0519424A BRPI0519424A BRPI0519424B8 BR PI0519424 B8 BRPI0519424 B8 BR PI0519424B8 BR PI0519424 A BRPI0519424 A BR PI0519424A BR PI0519424 A BRPI0519424 A BR PI0519424A BR PI0519424 B8 BRPI0519424 B8 BR PI0519424B8
Authority
BR
Brazil
Prior art keywords
compounds
preparation
treating
medicament
preventing
Prior art date
Application number
BRPI0519424A
Other languages
English (en)
Portuguese (pt)
Inventor
G Hangauer David
Original Assignee
Athenex Inc
Kinex Pharmaceuticals Inc
Kinex Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36615518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0519424(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Athenex Inc, Kinex Pharmaceuticals Inc, Kinex Pharmaceuticals Llc filed Critical Athenex Inc
Publication of BRPI0519424A2 publication Critical patent/BRPI0519424A2/pt
Publication of BRPI0519424B1 publication Critical patent/BRPI0519424B1/pt
Publication of BRPI0519424B8 publication Critical patent/BRPI0519424B8/pt

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
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US9655903B2 (en) 2017-05-23
EP1836169B1 (en) 2012-02-08
PL1836169T3 (pl) 2012-07-31
US20060160800A1 (en) 2006-07-20
HK1108695A1 (en) 2008-05-16
US8003641B2 (en) 2011-08-23
WO2006071960A2 (en) 2006-07-06
CY2022001I1 (el) 2022-03-24
HUS2100051I1 (hu) 2021-12-28
WO2006071960A3 (en) 2007-05-24
US20240050438A1 (en) 2024-02-15
CN101184734A (zh) 2008-05-21
HK1188985A1 (zh) 2014-05-23
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DK1836169T3 (da) 2012-03-26
ES2382068T3 (es) 2012-06-05
EP1836169A2 (en) 2007-09-26
FR21C1064I2 (fr) 2022-11-18
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US20150182532A1 (en) 2015-07-02
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KR101478933B1 (ko) 2015-01-02
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CN103274961A (zh) 2013-09-04
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