BRPI0807487A8 - Uso de antagonistas de il-23 para o tratamento de infecção - Google Patents

Uso de antagonistas de il-23 para o tratamento de infecção

Info

Publication number
BRPI0807487A8
BRPI0807487A8 BRPI0807487A BRPI0807487A BRPI0807487A8 BR PI0807487 A8 BRPI0807487 A8 BR PI0807487A8 BR PI0807487 A BRPI0807487 A BR PI0807487A BR PI0807487 A BRPI0807487 A BR PI0807487A BR PI0807487 A8 BRPI0807487 A8 BR PI0807487A8
Authority
BR
Brazil
Prior art keywords
antagonists
treatment
infection
infections
viral
Prior art date
Application number
BRPI0807487A
Other languages
English (en)
Inventor
Kopf Manfred
Romani Lugina
A Kastelein Robert
A Chackerian Alissa
Original Assignee
Schering Corp
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, Merck Sharp & Dohme filed Critical Schering Corp
Publication of BRPI0807487A2 publication Critical patent/BRPI0807487A2/pt
Publication of BRPI0807487A8 publication Critical patent/BRPI0807487A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

USOS DE ANTAGONISTAS DE IL-23, KIT E COMPOSIÇÃO FARMACÊUTICA OU ESTÉRIL. A presente invenção refere-se a métodos e composições compreendendo antagonistas de IL-23 para o tratamento de infecções, tais como infecções crônicas bacterianas, virais e fúngicas.
BRPI0807487A 2007-02-12 2008-02-08 Uso de antagonistas de il-23 para o tratamento de infecção BRPI0807487A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88947507P 2007-02-12 2007-02-12
PCT/US2008/001717 WO2008153610A2 (en) 2007-02-12 2008-02-08 Use of il-23 antagonists for treatment of infection

Publications (2)

Publication Number Publication Date
BRPI0807487A2 BRPI0807487A2 (pt) 2015-09-01
BRPI0807487A8 true BRPI0807487A8 (pt) 2016-02-10

Family

ID=40130357

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807487A BRPI0807487A8 (pt) 2007-02-12 2008-02-08 Uso de antagonistas de il-23 para o tratamento de infecção

Country Status (13)

Country Link
US (2) US8586035B2 (pt)
EP (1) EP2064246B1 (pt)
JP (2) JP5320301B2 (pt)
CN (1) CN101668775B (pt)
AU (1) AU2008262544B2 (pt)
BR (1) BRPI0807487A8 (pt)
CA (1) CA2677835A1 (pt)
CL (1) CL2008000418A1 (pt)
MX (1) MX2009008617A (pt)
NZ (2) NZ578955A (pt)
TW (1) TWI426918B (pt)
WO (1) WO2008153610A2 (pt)
ZA (1) ZA200906126B (pt)

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CA2822775A1 (en) * 2011-01-04 2012-07-12 Charite Universitatsmedizin Berlin Modulators of il-12 and/or il-23 for the prevention or treatment of alzheimer's disease
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
UY34401A (es) 2011-10-21 2013-05-31 Abbvie Inc Métodos para el tratamiento de hcv
DE202012012956U1 (de) 2011-10-21 2014-10-16 Abbvie Inc. Kombination aus mindestens zwei direkt wirkenden antiviralen Wirkstoffen für die Verwendung zur Behandlung von HCV, umfassend Ribavirin aber nicht Interferon
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
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UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
US10406218B2 (en) * 2014-04-09 2019-09-10 La Jolla Institute For Allergy And Immunology Specific and unique T cell responses and molecular signatures for the treatment and diagnosis of Mycobacterium tuberculosis
JP2017524359A (ja) 2014-07-24 2017-08-31 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｉｌ−２３ａ関連疾患の処置に有用なバイオマーカー
EA039598B9 (ru) 2014-09-03 2022-03-10 Бёрингер Ингельхайм Интернациональ Гмбх Соединение, нацеленное на ил-23а и фно-альфа, и его применение
CN105420238A (zh) * 2015-09-08 2016-03-23 中国农业科学院兰州兽医研究所 靶向抑制小鼠白细胞介素17A基因的序列siRNA-136
WO2017189978A1 (en) 2016-04-28 2017-11-02 Emory University Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto
WO2018067520A2 (en) * 2016-10-04 2018-04-12 Pop Test Oncology Llc Therapeutic agents and methods:
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
SG11201909955XA (en) 2017-05-02 2019-11-28 Merck Sharp & Dohme Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
US20200197389A1 (en) * 2017-05-12 2020-06-25 The Regents Of The University Of California Methods for detecting dysbiosis and treating subjects with dysbiosis
CN108743603B (zh) * 2018-06-22 2020-06-30 山东省千佛山医院 利巴韦林单用或联合氟康唑的抗真菌产品及其应用
WO2020096058A1 (ja) * 2018-11-09 2020-05-14 学校法人立命館 皮脂腺調整剤
CN112500490B (zh) * 2020-10-14 2022-05-03 华南农业大学 一种抗左旋氧氟沙星抗体的F(ab)2片段及其制备方法和应用

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Also Published As

Publication number Publication date
JP5320301B2 (ja) 2013-10-23
JP2013014624A (ja) 2013-01-24
AU2008262544B2 (en) 2014-01-16
US8586035B2 (en) 2013-11-19
US20140147442A1 (en) 2014-05-29
EP2064246A2 (en) 2009-06-03
CA2677835A1 (en) 2008-12-18
NZ578955A (en) 2012-06-29
CN101668775B (zh) 2014-05-07
US20100291084A1 (en) 2010-11-18
MX2009008617A (es) 2009-10-14
WO2008153610A2 (en) 2008-12-18
BRPI0807487A2 (pt) 2015-09-01
WO2008153610A3 (en) 2009-03-19
CL2008000418A1 (es) 2008-11-14
TW200902062A (en) 2009-01-16
CN101668775A (zh) 2010-03-10
JP2010518087A (ja) 2010-05-27
NZ599827A (en) 2013-11-29
ZA200906126B (en) 2010-06-30
TWI426918B (zh) 2014-02-21
EP2064246B1 (en) 2013-05-22
AU2008262544A1 (en) 2008-12-18

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B25D Requested change of name of applicant approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B25G Requested change of headquarter approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]