BRPI0815920A2 - Composto, composição farmacêutica, e, uso do composto. - Google Patents
Composto, composição farmacêutica, e, uso do composto.Info
- Publication number
- BRPI0815920A2 BRPI0815920A2 BRPI0815920-3A2A BRPI0815920A BRPI0815920A2 BR PI0815920 A2 BRPI0815920 A2 BR PI0815920A2 BR PI0815920 A BRPI0815920 A BR PI0815920A BR PI0815920 A2 BRPI0815920 A2 BR PI0815920A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutical composition
- iva
- formulas
- host
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229940123066 Polymerase inhibitor Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65848—Cyclic amide derivatives of acids of phosphorus, in which two nitrogen atoms belong to the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96723707P | 2007-08-31 | 2007-08-31 | |
| PCT/US2008/010225 WO2009032180A1 (en) | 2007-08-31 | 2008-08-28 | Phosphadiazine hcv polymerase inhibitors iv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0815920A2 true BRPI0815920A2 (pt) | 2015-02-18 |
Family
ID=39874081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0815920-3A2A BRPI0815920A2 (pt) | 2007-08-31 | 2008-08-28 | Composto, composição farmacêutica, e, uso do composto. |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US20090060866A1 (pt) |
| EP (1) | EP2183260B1 (pt) |
| JP (1) | JP5514108B2 (pt) |
| KR (1) | KR20100072002A (pt) |
| CN (1) | CN101842378A (pt) |
| AT (1) | ATE511514T1 (pt) |
| AU (1) | AU2008296997B2 (pt) |
| BR (1) | BRPI0815920A2 (pt) |
| CA (1) | CA2697546A1 (pt) |
| ES (1) | ES2367550T3 (pt) |
| HK (1) | HK1137028A1 (pt) |
| MX (1) | MX2010002296A (pt) |
| NZ (1) | NZ583545A (pt) |
| RU (1) | RU2483073C2 (pt) |
| TW (1) | TW200927143A (pt) |
| UA (1) | UA95715C2 (pt) |
| WO (4) | WO2009032179A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2389934A1 (en) * | 2010-05-25 | 2011-11-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Controlled-Release Tablet Formulations of Pregabalin |
| US20120252721A1 (en) | 2011-03-31 | 2012-10-04 | Idenix Pharmaceuticals, Inc. | Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor |
| WO2015042375A1 (en) | 2013-09-20 | 2015-03-26 | Idenix Pharmaceuticals, Inc. | Hepatitis c virus inhibitors |
| EP3114122A1 (en) | 2014-03-05 | 2017-01-11 | Idenix Pharmaceuticals LLC | Solid forms of a flaviviridae virus inhibitor compound and salts thereof |
| KR102363946B1 (ko) | 2015-03-06 | 2022-02-17 | 아테아 파마슈티컬즈, 인크. | HCV 치료를 위한 β-D-2'-데옥시-2'-α-플루오로-2'-β-C-치환된-2-변형된-N6-치환된 퓨린 뉴클레오티드 |
| US10766917B2 (en) | 2015-05-27 | 2020-09-08 | Idenix Pharmaceuticals Llc | Nucleotides for the treatment of cancer |
| CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
| CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
| EP3455218A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| WO2018013937A1 (en) | 2016-07-14 | 2018-01-18 | Atea Pharmaceuticals, Inc. | Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection |
| KR20190043602A (ko) | 2016-09-07 | 2019-04-26 | 아테아 파마슈티컬즈, 인크. | Rna 바이러스 치료를 위한 2'-치환된-n6-치환된 퓨린 뉴클레오티드 |
| GEP20237457B (en) | 2017-02-01 | 2023-01-10 | Atea Pharmaceuticals Inc | Nucleotide hemi-sulfate salt for treatment of hepatitis c virus |
| TW202012001A (zh) | 2018-04-10 | 2020-04-01 | 美商亞堤製藥公司 | C型肝炎病毒(hcv)感染硬化之患者的治療 |
| CN111233925B (zh) * | 2018-11-28 | 2021-03-26 | 上海日馨生物科技有限公司 | 硫胺类化合物、制备方法及其药物组合物 |
| US10874687B1 (en) | 2020-02-27 | 2020-12-29 | Atea Pharmaceuticals, Inc. | Highly active compounds against COVID-19 |
| CN113698315A (zh) * | 2021-09-03 | 2021-11-26 | 内蒙古蓝科生物科技有限公司 | 一种2-三氟甲基苯甲酰胺的合成方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU495317A1 (ru) * | 1973-11-14 | 1975-12-15 | Киевский научно-исследовательский институт фармакологии и токсикологии | Способ получени этилениминопроизводных 1,2,6-фосфадиазинов |
| MXPA01008937A (es) * | 1999-03-05 | 2004-04-05 | Metabasis Therapeutics Inc | Nuevos profarmacos que contienen fosforo. |
| EP1634886A3 (en) | 1999-03-05 | 2006-03-29 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing prodrug |
| AU4329000A (en) * | 1999-04-19 | 2000-11-02 | G.D. Searle & Co. | Novel heterocyclic amino carbonyl derivatives useful as nitric oxide synthase inhibitors |
| WO2003099801A1 (en) * | 2002-05-24 | 2003-12-04 | Smithkline Beecham Corporation | Novel anti-infectives |
| EP1786807B1 (en) * | 2004-08-23 | 2009-07-29 | F.Hoffmann-La Roche Ag | Heterocyclic antiviral compounds |
| DE602007011213D1 (de) * | 2006-02-17 | 2011-01-27 | Hoffmann La Roche | Heterocyclische antivirale verbindungen |
-
2008
- 2008-08-27 US US12/198,898 patent/US20090060866A1/en not_active Abandoned
- 2008-08-27 US US12/198,895 patent/US7932240B2/en active Active
- 2008-08-27 US US12/198,901 patent/US20090060867A1/en not_active Abandoned
- 2008-08-27 US US12/198,900 patent/US20090060872A1/en not_active Abandoned
- 2008-08-28 AU AU2008296997A patent/AU2008296997B2/en not_active Ceased
- 2008-08-28 NZ NZ583545A patent/NZ583545A/en not_active IP Right Cessation
- 2008-08-28 WO PCT/US2008/010224 patent/WO2009032179A1/en active Application Filing
- 2008-08-28 UA UAA201003681A patent/UA95715C2/ru unknown
- 2008-08-28 WO PCT/US2008/010219 patent/WO2009032176A1/en active Application Filing
- 2008-08-28 BR BRPI0815920-3A2A patent/BRPI0815920A2/pt not_active IP Right Cessation
- 2008-08-28 KR KR1020107006918A patent/KR20100072002A/ko not_active Application Discontinuation
- 2008-08-28 CA CA2697546A patent/CA2697546A1/en not_active Abandoned
- 2008-08-28 WO PCT/US2008/010220 patent/WO2009032177A1/en active Application Filing
- 2008-08-28 JP JP2010522959A patent/JP5514108B2/ja not_active Expired - Fee Related
- 2008-08-28 ES ES08829413T patent/ES2367550T3/es active Active
- 2008-08-28 EP EP08829413A patent/EP2183260B1/en active Active
- 2008-08-28 AT AT08829413T patent/ATE511514T1/de not_active IP Right Cessation
- 2008-08-28 WO PCT/US2008/010225 patent/WO2009032180A1/en active Application Filing
- 2008-08-28 CN CN200880114339A patent/CN101842378A/zh active Pending
- 2008-08-28 MX MX2010002296A patent/MX2010002296A/es active IP Right Grant
- 2008-08-28 RU RU2010112408/04A patent/RU2483073C2/ru not_active IP Right Cessation
- 2008-08-29 TW TW097133383A patent/TW200927143A/zh unknown
-
2010
- 2010-05-18 HK HK10104852.7A patent/HK1137028A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008296997A1 (en) | 2009-03-12 |
| HK1137028A1 (en) | 2010-07-16 |
| RU2483073C2 (ru) | 2013-05-27 |
| US20090081158A1 (en) | 2009-03-26 |
| ATE511514T1 (de) | 2011-06-15 |
| US20090060872A1 (en) | 2009-03-05 |
| NZ583545A (en) | 2011-04-29 |
| US20090060866A1 (en) | 2009-03-05 |
| WO2009032176A1 (en) | 2009-03-12 |
| WO2009032179A1 (en) | 2009-03-12 |
| KR20100072002A (ko) | 2010-06-29 |
| UA95715C2 (ru) | 2011-08-25 |
| EP2183260A1 (en) | 2010-05-12 |
| WO2009032180A1 (en) | 2009-03-12 |
| CN101842378A (zh) | 2010-09-22 |
| MX2010002296A (es) | 2010-04-01 |
| JP5514108B2 (ja) | 2014-06-04 |
| US20090060867A1 (en) | 2009-03-05 |
| EP2183260B1 (en) | 2011-06-01 |
| JP2010537986A (ja) | 2010-12-09 |
| US7932240B2 (en) | 2011-04-26 |
| WO2009032177A1 (en) | 2009-03-12 |
| RU2010112408A (ru) | 2011-10-10 |
| CA2697546A1 (en) | 2009-03-12 |
| ES2367550T3 (es) | 2011-11-04 |
| AU2008296997B2 (en) | 2013-08-29 |
| TW200927143A (en) | 2009-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |