UA95715C2 - Фосфадиазиновые производные, фармацевтическая композиция и их применение - Google Patents
Фосфадиазиновые производные, фармацевтическая композиция и их применениеInfo
- Publication number
- UA95715C2 UA95715C2 UAA201003681A UAA201003681A UA95715C2 UA 95715 C2 UA95715 C2 UA 95715C2 UA A201003681 A UAA201003681 A UA A201003681A UA A201003681 A UAA201003681 A UA A201003681A UA 95715 C2 UA95715 C2 UA 95715C2
- Authority
- UA
- Ukraine
- Prior art keywords
- phosphadiazine
- derivatives
- pharmaceutical composition
- iva
- formulas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65848—Cyclic amide derivatives of acids of phosphorus, in which two nitrogen atoms belong to the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96723707P | 2007-08-31 | 2007-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA95715C2 true UA95715C2 (ru) | 2011-08-25 |
Family
ID=39874081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201003681A UA95715C2 (ru) | 2007-08-31 | 2008-08-28 | Фосфадиазиновые производные, фармацевтическая композиция и их применение |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US20090060866A1 (ru) |
| EP (1) | EP2183260B1 (ru) |
| JP (1) | JP5514108B2 (ru) |
| KR (1) | KR20100072002A (ru) |
| CN (1) | CN101842378A (ru) |
| AT (1) | ATE511514T1 (ru) |
| AU (1) | AU2008296997B2 (ru) |
| BR (1) | BRPI0815920A2 (ru) |
| CA (1) | CA2697546A1 (ru) |
| ES (1) | ES2367550T3 (ru) |
| HK (1) | HK1137028A1 (ru) |
| MX (1) | MX2010002296A (ru) |
| NZ (1) | NZ583545A (ru) |
| RU (1) | RU2483073C2 (ru) |
| TW (1) | TW200927143A (ru) |
| UA (1) | UA95715C2 (ru) |
| WO (4) | WO2009032176A1 (ru) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2389934A1 (en) * | 2010-05-25 | 2011-11-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Controlled-Release Tablet Formulations of Pregabalin |
| US20120252721A1 (en) | 2011-03-31 | 2012-10-04 | Idenix Pharmaceuticals, Inc. | Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor |
| US20160229866A1 (en) | 2013-09-20 | 2016-08-11 | Idenix Pharmaceuticals Inc. | Hepatitis c virus inhibitors |
| EP3114122A1 (en) | 2014-03-05 | 2017-01-11 | Idenix Pharmaceuticals LLC | Solid forms of a flaviviridae virus inhibitor compound and salts thereof |
| RU2764767C2 (ru) | 2015-03-06 | 2022-01-21 | Атеа Фармасьютикалс, Инк. | β-D-2'-ДЕЗОКСИ-2'-α-ФТОР-2'-β-С-ЗАМЕЩЕННЫЕ-2-МОДИФИЦИРОВАННЫЕ-N6-ЗАМЕЩЕННЫЕ ПУРИНОВЫЕ НУКЛЕОТИДЫ ДЛЯ ЛЕЧЕНИЯ ВЫЗВАННЫХ HCV ЗАБОЛЕВАНИЙ |
| EP3303359A1 (en) | 2015-05-27 | 2018-04-11 | Idenix Pharmaceuticals LLC | Nucleotides for the treatment of cancer |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
| WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| US10711029B2 (en) | 2016-07-14 | 2020-07-14 | Atea Pharmaceuticals, Inc. | Beta-d-2′-deoxy-2′-alpha-fluoro-2′-beta-c-substituted-4′fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection |
| PL3512863T3 (pl) | 2016-09-07 | 2022-04-04 | Atea Pharmaceuticals, Inc. | 2'-Podstawione-N6-podstawione nukleotydy purynowe do leczenia zakażeń wirusem RNA |
| SG10202012214WA (en) | 2017-02-01 | 2021-01-28 | Atea Pharmaceuticals Inc | Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus |
| WO2019200005A1 (en) | 2018-04-10 | 2019-10-17 | Atea Pharmaceuticals, Inc. | Treatment of hcv infected patients with cirrhosis |
| CN111233925B (zh) * | 2018-11-28 | 2021-03-26 | 上海日馨生物科技有限公司 | 硫胺类化合物、制备方法及其药物组合物 |
| US10874687B1 (en) | 2020-02-27 | 2020-12-29 | Atea Pharmaceuticals, Inc. | Highly active compounds against COVID-19 |
| CN113698315A (zh) * | 2021-09-03 | 2021-11-26 | 内蒙古蓝科生物科技有限公司 | 一种2-三氟甲基苯甲酰胺的合成方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU495317A1 (ru) * | 1973-11-14 | 1975-12-15 | Киевский научно-исследовательский институт фармакологии и токсикологии | Способ получени этилениминопроизводных 1,2,6-фосфадиазинов |
| EP1634886A3 (en) | 1999-03-05 | 2006-03-29 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing prodrug |
| HUP0200260A3 (en) * | 1999-03-05 | 2002-11-28 | Metabasis Therapeutics Inc San | Novel phosphorus-containing prodrugs, their preparation and their use |
| WO2000063195A1 (en) * | 1999-04-19 | 2000-10-26 | G.D. Searle & Co. | Novel heterocyclic amino carbonyl derivatives useful as nitric oxide synthase inhibitors |
| WO2003099801A1 (en) * | 2002-05-24 | 2003-12-04 | Smithkline Beecham Corporation | Novel anti-infectives |
| RU2007110531A (ru) * | 2004-08-23 | 2008-09-27 | Ф.Хоффманн-Ля Рош Аг (Ch) | Гетероциклические противовирусные соединения |
| DE602007011213D1 (de) * | 2006-02-17 | 2011-01-27 | Hoffmann La Roche | Heterocyclische antivirale verbindungen |
-
2008
- 2008-08-27 US US12/198,898 patent/US20090060866A1/en not_active Abandoned
- 2008-08-27 US US12/198,895 patent/US7932240B2/en active Active
- 2008-08-27 US US12/198,900 patent/US20090060872A1/en not_active Abandoned
- 2008-08-27 US US12/198,901 patent/US20090060867A1/en not_active Abandoned
- 2008-08-28 CN CN200880114339A patent/CN101842378A/zh active Pending
- 2008-08-28 AT AT08829413T patent/ATE511514T1/de not_active IP Right Cessation
- 2008-08-28 CA CA2697546A patent/CA2697546A1/en not_active Abandoned
- 2008-08-28 WO PCT/US2008/010219 patent/WO2009032176A1/en active Application Filing
- 2008-08-28 RU RU2010112408/04A patent/RU2483073C2/ru not_active IP Right Cessation
- 2008-08-28 KR KR1020107006918A patent/KR20100072002A/ko not_active Application Discontinuation
- 2008-08-28 MX MX2010002296A patent/MX2010002296A/es active IP Right Grant
- 2008-08-28 WO PCT/US2008/010220 patent/WO2009032177A1/en active Application Filing
- 2008-08-28 EP EP08829413A patent/EP2183260B1/en active Active
- 2008-08-28 AU AU2008296997A patent/AU2008296997B2/en not_active Ceased
- 2008-08-28 WO PCT/US2008/010224 patent/WO2009032179A1/en active Application Filing
- 2008-08-28 JP JP2010522959A patent/JP5514108B2/ja not_active Expired - Fee Related
- 2008-08-28 UA UAA201003681A patent/UA95715C2/ru unknown
- 2008-08-28 ES ES08829413T patent/ES2367550T3/es active Active
- 2008-08-28 BR BRPI0815920-3A2A patent/BRPI0815920A2/pt not_active IP Right Cessation
- 2008-08-28 WO PCT/US2008/010225 patent/WO2009032180A1/en active Application Filing
- 2008-08-28 NZ NZ583545A patent/NZ583545A/en not_active IP Right Cessation
- 2008-08-29 TW TW097133383A patent/TW200927143A/zh unknown
-
2010
- 2010-05-18 HK HK10104852.7A patent/HK1137028A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008296997A1 (en) | 2009-03-12 |
| WO2009032180A1 (en) | 2009-03-12 |
| RU2483073C2 (ru) | 2013-05-27 |
| US20090060866A1 (en) | 2009-03-05 |
| CA2697546A1 (en) | 2009-03-12 |
| ES2367550T3 (es) | 2011-11-04 |
| JP2010537986A (ja) | 2010-12-09 |
| CN101842378A (zh) | 2010-09-22 |
| EP2183260B1 (en) | 2011-06-01 |
| BRPI0815920A2 (pt) | 2015-02-18 |
| NZ583545A (en) | 2011-04-29 |
| HK1137028A1 (en) | 2010-07-16 |
| WO2009032176A1 (en) | 2009-03-12 |
| US20090081158A1 (en) | 2009-03-26 |
| RU2010112408A (ru) | 2011-10-10 |
| TW200927143A (en) | 2009-07-01 |
| WO2009032179A1 (en) | 2009-03-12 |
| US20090060872A1 (en) | 2009-03-05 |
| EP2183260A1 (en) | 2010-05-12 |
| US7932240B2 (en) | 2011-04-26 |
| ATE511514T1 (de) | 2011-06-15 |
| KR20100072002A (ko) | 2010-06-29 |
| JP5514108B2 (ja) | 2014-06-04 |
| US20090060867A1 (en) | 2009-03-05 |
| MX2010002296A (es) | 2010-04-01 |
| AU2008296997B2 (en) | 2013-08-29 |
| WO2009032177A1 (en) | 2009-03-12 |
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