BRPI0513437A - célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação - Google Patents
célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentaçãoInfo
- Publication number
- BRPI0513437A BRPI0513437A BRPI0513437-4A BRPI0513437A BRPI0513437A BR PI0513437 A BRPI0513437 A BR PI0513437A BR PI0513437 A BRPI0513437 A BR PI0513437A BR PI0513437 A BRPI0513437 A BR PI0513437A
- Authority
- BR
- Brazil
- Prior art keywords
- xylose
- ability
- processes
- host cell
- xylulose
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
CéLULA HOSPEDEIRA EUCARIóTICA COM A CAPACIDADE PARA ISOMERIZAR DIRETAMENTE XILOSE EM XILULOSE, E, PROCESSOS PARA PRODUZIR ETANOL E UM PRODUTO DE FERMENTAçãO A presente invenção diz respeito a modificações genéticas adicionais em células hospedeiras eucarióticas que foram transformadas para expressar uma xilose isomerase que confere à célula hospedeira a capacidade de isomerizar xilose para xilulose. As modificações genéticas adicionais são intencionadas a melhorar a eficiência do metabolismo de xilose e incluem por exemplo, a redução da atividade da aldose redutase não específica, atividade da xilulose quinase aumentada e fluxo aumentada do caminho da pentose fosfato. As células hospedeiras modificadas da invenção são adequadas para a produção de uma ampla variedade de produtos de fermentação, incluindo etanol, em processos de fermentação em que uma fonte de xilose ou uma fonte de xilose e glicose são usadas como fonte de carbono.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58838104P | 2004-07-16 | 2004-07-16 | |
EP04077073 | 2004-07-16 | ||
US58983304P | 2004-07-22 | 2004-07-22 | |
PCT/NL2005/000516 WO2006009434A1 (en) | 2004-07-16 | 2005-07-15 | Metabolic engineering of xylose fermenting eukaryotic cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0513437A true BRPI0513437A (pt) | 2008-05-06 |
Family
ID=34928378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0513437-4A BRPI0513437A (pt) | 2004-07-16 | 2005-07-15 | célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação |
Country Status (10)
Country | Link |
---|---|
US (3) | US8034591B2 (pt) |
EP (1) | EP1781772B1 (pt) |
JP (2) | JP5796925B2 (pt) |
CN (2) | CN101914462B (pt) |
BR (1) | BRPI0513437A (pt) |
CA (2) | CA2573483C (pt) |
DK (1) | DK1781772T3 (pt) |
ES (1) | ES2607891T3 (pt) |
PL (1) | PL1781772T3 (pt) |
WO (1) | WO2006009434A1 (pt) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016065453A1 (pt) * | 2014-10-30 | 2016-05-06 | Biocelere Agroindustrial Ltda. | Cassete de expressão para a transformação de célula eucariótica, processo para a transformação de célula eucariótica, micro-organismo geneticamente modificado, processo de produção de biocombustíveis e/ou bioquímicos e biocombustível e/ou bioquímico assim produzidos |
Families Citing this family (121)
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WO2019219804A1 (en) | 2018-05-17 | 2019-11-21 | Dsm Ip Assets B.V. | Process for producing a polypeptide |
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WO2020058253A1 (en) | 2018-09-18 | 2020-03-26 | Dsm Ip Assets B.V. | Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars |
AU2019365525A1 (en) * | 2018-10-23 | 2021-05-13 | MARA Renewables Corporation | Adaptation and process optimization of microorganisms for growth in hemicellulosic derived carbohydrates |
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US20220380813A1 (en) | 2019-11-08 | 2022-12-01 | Dsm Ip Assets B.V. | Process for producing ethanol |
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CA3214435A1 (en) | 2021-04-06 | 2022-10-13 | Dsm Ip Assets B.V. | Enzyme composition |
CN117178060A (zh) | 2021-04-06 | 2023-12-05 | 帝斯曼知识产权资产管理有限公司 | 酶组合物 |
WO2022214459A1 (en) | 2021-04-06 | 2022-10-13 | Dsm Ip Assets B.V. | Enzyme composition |
AU2022253636A1 (en) | 2021-04-08 | 2023-06-01 | Versalis S.P.A. | Process for the preparation of a sugar product and a fermentation product |
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JPH10117771A (ja) * | 1996-10-23 | 1998-05-12 | Natl Food Res Inst | 冷凍生地耐性実用パン酵母 |
US6566107B1 (en) * | 2000-11-01 | 2003-05-20 | Midwest Research Institute | Recombinant Zymomonas mobilis with improved xylose utilization |
DE60325457D1 (de) | 2002-01-23 | 2009-02-05 | Royal Nedalco B V | Fermentation von pentosezuckern |
PL2301949T3 (pl) * | 2003-05-02 | 2015-10-30 | Cargill Inc | Genetycznie modyfikowane gatunki drożdży i sposoby fermentacji z użyciem genetycznie modyfikowanych drożdży |
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WO2016065453A1 (pt) * | 2014-10-30 | 2016-05-06 | Biocelere Agroindustrial Ltda. | Cassete de expressão para a transformação de célula eucariótica, processo para a transformação de célula eucariótica, micro-organismo geneticamente modificado, processo de produção de biocombustíveis e/ou bioquímicos e biocombustível e/ou bioquímico assim produzidos |
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CA2861834A1 (en) | 2006-01-26 |
JP5796925B2 (ja) | 2015-10-21 |
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US20120225451A1 (en) | 2012-09-06 |
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US20080261287A1 (en) | 2008-10-23 |
CA2573483C (en) | 2014-10-28 |
JP2008506383A (ja) | 2008-03-06 |
CN101052706A (zh) | 2007-10-10 |
CN101914462B (zh) | 2013-04-24 |
CN101052706B (zh) | 2015-02-18 |
DK1781772T3 (en) | 2017-01-09 |
US20150010943A1 (en) | 2015-01-08 |
CA2573483A1 (en) | 2006-01-26 |
ES2607891T3 (es) | 2017-04-04 |
CN101914462A (zh) | 2010-12-15 |
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