BRPI0415744A - lipìdios contendo ácidos graxos Èmega-3 e Èmega-6 - Google Patents
lipìdios contendo ácidos graxos Èmega-3 e Èmega-6Info
- Publication number
- BRPI0415744A BRPI0415744A BRPI0415744-3A BRPI0415744A BRPI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A
- Authority
- BR
- Brazil
- Prior art keywords
- omega
- pufa
- fatty acids
- lipids containing
- glycerophospholipid
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 235000020660 omega-3 fatty acid Nutrition 0.000 title abstract 2
- 229940012843 omega-3 fatty acid Drugs 0.000 title 1
- 235000020665 omega-6 fatty acid Nutrition 0.000 title 1
- 229940033080 omega-6 fatty acid Drugs 0.000 title 1
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 3
- PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 abstract 2
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 abstract 2
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 2
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 abstract 2
- ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 abstract 2
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 abstract 2
- 150000002327 glycerophospholipids Chemical class 0.000 abstract 2
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 abstract 2
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 2
- 150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000006998 cognitive state Effects 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 230000006870 function Effects 0.000 abstract 1
- 230000006996 mental state Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
Abstract
"LIPìDIOS CONTENDO áCIDOS GRAXOS ÈMEGA-3 E ÈMEGA-6". Apresenta-se uma preparação lipídica compreendendo um glicerofosfolipídio ou seu sal, conjugado ou derivado, particularmente fosfaditilserina (PS), fosfatidilcolina (PC), fosfatidiletanolamina (PE), fosfatidilinositol (PI), fosfatidilglicerol (PG) e ácido fosfatídico (PA) e grupos acila de ácido graxo poliinsaturado (PUFA), particularmente grupos acila de ácido graxo poliinsaturado de cadeia longa (LC-PUFA), como grupos acila ómega-3 e/ou ómega-6, em que o dito PUFA está covalentemente ligado ao dito glicerofosfolipídio. As preparações apresentadas possuem uma melhor bioatividade e são utilizáveis no tratamento de vários estados e distúrbios cognitivos e mentais e para a manutenção das funções normais de sistemas e processos relacionados ao cérebro.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL15855203A IL158552A0 (en) | 2003-10-22 | 2003-10-22 | Lipids containing omega-3 fatty acids |
| PCT/IL2004/000957 WO2005037848A2 (en) | 2003-10-22 | 2004-10-21 | Glycerophospholipids containing omega-3 and omega-6 fatty acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0415744A true BRPI0415744A (pt) | 2006-12-19 |
| BRPI0415744B1 BRPI0415744B1 (pt) | 2018-07-17 |
| BRPI0415744B8 BRPI0415744B8 (pt) | 2021-05-25 |
Family
ID=34044222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415744A BRPI0415744B8 (pt) | 2003-10-22 | 2004-10-21 | uso de uma preparação lipídica contendo ácidos graxos ômega-3 e ômega-6, esta preparação, uso de glicerofosfolipídios, composição nutracêutica e artigo alimentar funcional |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP2258377B1 (pt) |
| JP (2) | JP2007509131A (pt) |
| KR (2) | KR101331658B1 (pt) |
| CN (2) | CN1897955A (pt) |
| AU (1) | AU2004282006C1 (pt) |
| BR (1) | BRPI0415744B8 (pt) |
| CA (1) | CA2542504C (pt) |
| IL (3) | IL158552A0 (pt) |
| RU (1) | RU2362566C2 (pt) |
| WO (1) | WO2005037848A2 (pt) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003048831A (ja) | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
| US7935365B2 (en) * | 2003-10-22 | 2011-05-03 | Enzymotec, Ltd. | Glycerophospholipids for the improvement of cognitive functions |
| IL158552A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Lipids containing omega-3 fatty acids |
| IL158553A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Method for preparing phosphatidylserine containing omega-3 acid moieties |
| JP4993852B2 (ja) | 2004-09-17 | 2012-08-08 | サントリーホールディングス株式会社 | ストレスに起因する行動異常を伴う症状あるいは疾患の予防又は改善作用を有する組成物 |
| JP5967855B2 (ja) | 2005-06-30 | 2016-08-10 | サントリーホールディングス株式会社 | 日中活動量の低下および/又はうつ症状の改善作用を有する組成物 |
| JP5697293B2 (ja) * | 2005-06-30 | 2015-04-08 | サントリーホールディングス株式会社 | 器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する組成物 |
| CA2645123A1 (en) * | 2006-02-28 | 2007-09-07 | Bristol-Myers Squibb Company | Use of dha and ara in the preparation of a composition for regulating gene expression |
| JP2008260743A (ja) * | 2006-08-03 | 2008-10-30 | Nagase Chemtex Corp | Nqo1発現増強剤 |
| CN101631542B (zh) | 2006-12-28 | 2011-12-21 | 三得利控股株式会社 | 神经再生剂 |
| US8697138B2 (en) | 2007-03-28 | 2014-04-15 | Aker Biomarine As | Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders |
| PT2144618E (pt) | 2007-03-28 | 2013-07-08 | Aker Biomarine Asa | Composições bioeficazes de óleo de krill |
| CN101909467B (zh) * | 2007-11-01 | 2013-04-24 | 恩兹默泰克有限公司 | 用于婴儿营养的脂质混合物 |
| US9085527B2 (en) | 2008-07-08 | 2015-07-21 | Catabasis Pharmaceuticals, Inc. | Fatty acid acylated salicylates and their uses |
| US8372812B2 (en) | 2009-02-26 | 2013-02-12 | Aker Biomarine Asa | Phospholipid and protein tablets |
| US20130295171A1 (en) | 2009-07-23 | 2013-11-07 | U.S NUTRACEUTICALS, LLC d/b/a Valensa International | Krill oil and reacted astaxanthin composition and associated method |
| CA2989078C (en) | 2009-10-29 | 2020-06-30 | Acasti Pharma, Inc. | Concentrated therapeutic phosholipid compositions |
| EP2493296B1 (en) | 2009-10-30 | 2019-01-09 | Retrotope, Inc. | Alleviating oxidative stress disorders with pufa derivatives |
| AU2011214344A1 (en) * | 2010-02-11 | 2012-08-16 | KATHOLIEKE UNIVERSITEIT LEUVEN, KULeuven R&D | Phospholipid profiling and cancer |
| US8663704B2 (en) | 2010-04-30 | 2014-03-04 | U.S. Nutraceuticals, LLC | Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans |
| US9763897B2 (en) | 2010-04-30 | 2017-09-19 | U.S. Nutraceuticals, LLC | Therapeutic astaxanthin and phospholipid composition and associated method |
| WO2011137160A2 (en) * | 2010-04-30 | 2011-11-03 | U.S. Nutraceuticals, Llc D/B/A Valensa International | Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (ldl) per-oxidation in humans |
| RU2467334C2 (ru) * | 2010-08-24 | 2012-11-20 | Федеральное государственное бюджетное учреждение "Дальневосточный научный центр физиологии и патологии дыхания" Сибирского отделения РАМН | СПОСОБ ОЦЕНКИ МИКРОВЯЗКОСТИ МЕМБРАН ЭРИТРОЦИТОВ ПУТЕМ ВЫЧИСЛЕНИЯ КОЭФФИЦИЕНТА ЭКСИМЕРИЗАЦИИ ПИРЕНА Кэкс У БЕРЕМЕННЫХ, ПЕРЕНЕСШИХ ОБОСТРЕНИЕ ГЕРПЕС-ВИРУСНОЙ ИНФЕКЦИИ В ТРЕТЬЕМ ТРИМЕСТРЕ ГЕСТАЦИИ, С УЧЕТОМ ОПРЕДЕЛЕНИЯ ПРОЦЕНТНОГО СОДЕРЖАНИЯ ОЛЕИНОВОЙ КИСЛОТЫ В МЕМБРАНАХ ЭРИТРОЦИТОВ |
| GB201016139D0 (en) * | 2010-09-24 | 2010-11-10 | Univ Leuven Kath | Cancer phosholipidome |
| EP2701697B1 (en) | 2011-04-26 | 2020-03-25 | Retrotope, Inc. | Oxidative retinal diseases |
| US10154983B2 (en) | 2011-04-26 | 2018-12-18 | Retrotope, Inc. | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| ES2859753T3 (es) | 2011-04-26 | 2021-10-04 | Retrotope Inc | Trastornos que implican la oxidación de PUFA |
| WO2012148927A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Impaired energy processing disorders and mitochondrial deficiency |
| WO2013033618A1 (en) | 2011-09-02 | 2013-03-07 | Arctic Nutrition As | Lipid compositions with high dha content |
| RU2014139008A (ru) | 2012-02-29 | 2016-04-20 | Б. Браун Мельзунген Аг | Гормонсодержащая эмульсия, содержащая фосфолипиды криля |
| RU2667968C2 (ru) * | 2012-03-02 | 2018-09-25 | Н.В. Нютрисиа | Способ улучшения функциональной синаптической связи |
| US20150030718A1 (en) | 2012-03-12 | 2015-01-29 | Aker Biomarine Antarctic As | Oxidixable fatty acid composition delivery form |
| AU2013319911B2 (en) | 2012-09-19 | 2016-07-07 | Aker Biomarine Antarctic As | Omega-3 phospholipid supplements for females |
| WO2014140873A2 (en) | 2013-03-14 | 2014-09-18 | Aker Biomarine As | Omega- 3 phospholipid supplements for improved brain maturity |
| CN103242407A (zh) * | 2013-05-15 | 2013-08-14 | 张雅茹 | 含多不饱和脂肪酰基的磷脂酰甾醇和/或磷脂酰甾烷醇及制备方法和应用 |
| AU2014203179C1 (en) | 2013-06-14 | 2017-05-04 | Aker Biomarine Antarctic As | Lipid extraction processes |
| CN103609752B (zh) * | 2013-12-02 | 2016-05-25 | 内蒙古伊利实业集团股份有限公司 | 一种改善脑部认知功能的组合物及其制备方法与应用 |
| CA2932766C (en) | 2013-12-05 | 2018-05-01 | Enzymotec Ltd. | Serine glycerophospholipid preparation and method for treatment of seizures |
| GB201400431D0 (en) | 2014-01-10 | 2014-02-26 | Aker Biomarine As | Phospholipid compositions and their preparation |
| ES2788974T3 (es) * | 2014-04-30 | 2020-10-23 | Aker Biomarine Antarctic As | Preparaciones de aceite de krill y sus usos |
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| PT3256003T (pt) | 2015-02-11 | 2023-02-15 | Aker Biomarine Antarctic As | Processo de extração de lipídios |
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| JPH0279311A (ja) * | 1988-09-14 | 1990-03-19 | Ngk Insulators Ltd | 電気設備の高電圧瑞末部における接地層先端部の電界緩和構造及びその形成方法 |
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| GB9301629D0 (en) * | 1993-01-27 | 1993-03-17 | Scotia Holdings Plc | Formulations containing unsaturated fatty acids |
| JP3467794B2 (ja) * | 1993-03-09 | 2003-11-17 | 日本油脂株式会社 | 学習能向上剤 |
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| US5716614A (en) * | 1994-08-05 | 1998-02-10 | Molecular/Structural Biotechnologies, Inc. | Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier |
| AU2738497A (en) * | 1996-04-24 | 1997-11-12 | Brigham And Women's Hospital | Omega-3 fatty acids and omega-3 phosphatidylcholine in the treatment of bipolar disorder |
| US6344482B1 (en) * | 1997-04-23 | 2002-02-05 | Andrew L. Stoll | Omega-3 fatty acids in the treatment of bipolar disorder |
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| WO2004049907A2 (en) * | 2002-11-27 | 2004-06-17 | University Of Louisville Research Foundation | Compositions and methods for treating transplants |
| IL158552A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Lipids containing omega-3 fatty acids |
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2003
- 2003-10-22 IL IL15855203A patent/IL158552A0/xx unknown
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2004
- 2004-10-21 EP EP10180547.1A patent/EP2258377B1/en not_active Expired - Lifetime
- 2004-10-21 EP EP04791827A patent/EP1689413A2/en not_active Withdrawn
- 2004-10-21 KR KR1020067007683A patent/KR101331658B1/ko not_active Expired - Lifetime
- 2004-10-21 BR BRPI0415744A patent/BRPI0415744B8/pt active IP Right Grant
- 2004-10-21 RU RU2006116267/15A patent/RU2362566C2/ru active
- 2004-10-21 AU AU2004282006A patent/AU2004282006C1/en not_active Expired
- 2004-10-21 KR KR1020127022875A patent/KR20120115419A/ko not_active Ceased
- 2004-10-21 CN CNA200480038107XA patent/CN1897955A/zh active Pending
- 2004-10-21 WO PCT/IL2004/000957 patent/WO2005037848A2/en not_active Ceased
- 2004-10-21 JP JP2006536258A patent/JP2007509131A/ja active Pending
- 2004-10-21 CN CN2013102535938A patent/CN103381172A/zh active Pending
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| Publication number | Publication date |
|---|---|
| JP2012211168A (ja) | 2012-11-01 |
| CN1897955A (zh) | 2007-01-17 |
| IL174925A (en) | 2014-01-30 |
| IL158552A0 (en) | 2004-05-12 |
| RU2006116267A (ru) | 2007-12-10 |
| JP2007509131A (ja) | 2007-04-12 |
| KR20060094526A (ko) | 2006-08-29 |
| CA2542504A1 (en) | 2005-04-28 |
| RU2362566C2 (ru) | 2009-07-27 |
| AU2004282006B2 (en) | 2010-04-15 |
| IL174925A0 (en) | 2008-02-09 |
| CA2542504C (en) | 2014-01-07 |
| KR101331658B1 (ko) | 2013-11-20 |
| AU2004282006C1 (en) | 2010-10-21 |
| KR20120115419A (ko) | 2012-10-17 |
| EP2258377B1 (en) | 2019-08-28 |
| AU2004282006A1 (en) | 2005-04-28 |
| CN103381172A (zh) | 2013-11-06 |
| WO2005037848A2 (en) | 2005-04-28 |
| JP5835671B2 (ja) | 2015-12-24 |
| WO2005037848A3 (en) | 2005-05-26 |
| EP1689413A2 (en) | 2006-08-16 |
| BRPI0415744B1 (pt) | 2018-07-17 |
| IL224977A (en) | 2014-09-30 |
| BRPI0415744B8 (pt) | 2021-05-25 |
| EP2258377A3 (en) | 2011-10-05 |
| EP2258377A2 (en) | 2010-12-08 |
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