BRPI0415744A - lipìdios contendo ácidos graxos Èmega-3 e Èmega-6 - Google Patents
lipìdios contendo ácidos graxos Èmega-3 e Èmega-6Info
- Publication number
- BRPI0415744A BRPI0415744A BRPI0415744-3A BRPI0415744A BRPI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A
- Authority
- BR
- Brazil
- Prior art keywords
- omega
- pufa
- fatty acids
- lipids containing
- glycerophospholipid
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
Abstract
"LIPìDIOS CONTENDO áCIDOS GRAXOS ÈMEGA-3 E ÈMEGA-6". Apresenta-se uma preparação lipídica compreendendo um glicerofosfolipídio ou seu sal, conjugado ou derivado, particularmente fosfaditilserina (PS), fosfatidilcolina (PC), fosfatidiletanolamina (PE), fosfatidilinositol (PI), fosfatidilglicerol (PG) e ácido fosfatídico (PA) e grupos acila de ácido graxo poliinsaturado (PUFA), particularmente grupos acila de ácido graxo poliinsaturado de cadeia longa (LC-PUFA), como grupos acila ómega-3 e/ou ómega-6, em que o dito PUFA está covalentemente ligado ao dito glicerofosfolipídio. As preparações apresentadas possuem uma melhor bioatividade e são utilizáveis no tratamento de vários estados e distúrbios cognitivos e mentais e para a manutenção das funções normais de sistemas e processos relacionados ao cérebro.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL15855203A IL158552A0 (en) | 2003-10-22 | 2003-10-22 | Lipids containing omega-3 fatty acids |
| IL158552 | 2003-10-22 | ||
| PCT/IL2004/000957 WO2005037848A2 (en) | 2003-10-22 | 2004-10-21 | Glycerophospholipids containing omega-3 and omega-6 fatty acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0415744A true BRPI0415744A (pt) | 2006-12-19 |
| BRPI0415744B1 BRPI0415744B1 (pt) | 2018-07-17 |
| BRPI0415744B8 BRPI0415744B8 (pt) | 2021-05-25 |
Family
ID=34044222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415744A BRPI0415744B8 (pt) | 2003-10-22 | 2004-10-21 | uso de uma preparação lipídica contendo ácidos graxos ômega-3 e ômega-6, esta preparação, uso de glicerofosfolipídios, composição nutracêutica e artigo alimentar funcional |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP1689413A2 (pt) |
| JP (2) | JP2007509131A (pt) |
| KR (2) | KR20120115419A (pt) |
| CN (2) | CN1897955A (pt) |
| AU (1) | AU2004282006C1 (pt) |
| BR (1) | BRPI0415744B8 (pt) |
| CA (1) | CA2542504C (pt) |
| IL (3) | IL158552A0 (pt) |
| RU (1) | RU2362566C2 (pt) |
| WO (1) | WO2005037848A2 (pt) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003048831A (ja) | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
| IL158553A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Method for preparing phosphatidylserine containing omega-3 acid moieties |
| IL158552A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Lipids containing omega-3 fatty acids |
| US7935365B2 (en) * | 2003-10-22 | 2011-05-03 | Enzymotec, Ltd. | Glycerophospholipids for the improvement of cognitive functions |
| JP4993852B2 (ja) | 2004-09-17 | 2012-08-08 | サントリーホールディングス株式会社 | ストレスに起因する行動異常を伴う症状あるいは疾患の予防又は改善作用を有する組成物 |
| JP5697293B2 (ja) * | 2005-06-30 | 2015-04-08 | サントリーホールディングス株式会社 | 器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する組成物 |
| JP5967855B2 (ja) | 2005-06-30 | 2016-08-10 | サントリーホールディングス株式会社 | 日中活動量の低下および/又はうつ症状の改善作用を有する組成物 |
| MX2008010881A (es) * | 2006-02-28 | 2008-09-03 | Squibb Bristol Myers Co | Modulacion de expresiones de genes por el acido docosahexaenoico. |
| JP2008260743A (ja) * | 2006-08-03 | 2008-10-30 | Nagase Chemtex Corp | Nqo1発現増強剤 |
| JPWO2008081989A1 (ja) | 2006-12-28 | 2010-04-30 | サントリーホールディングス株式会社 | 神経再生剤 |
| WO2008117062A1 (en) | 2007-03-28 | 2008-10-02 | Aker Biomarine Asa | Bioeffective krill oil compositions |
| US8697138B2 (en) | 2007-03-28 | 2014-04-15 | Aker Biomarine As | Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders |
| MX2010004820A (es) * | 2007-11-01 | 2010-08-10 | Enzymotec Ltd | Mezcla lipidica para nutricion infantil. |
| US9085527B2 (en) | 2008-07-08 | 2015-07-21 | Catabasis Pharmaceuticals, Inc. | Fatty acid acylated salicylates and their uses |
| US8372812B2 (en) | 2009-02-26 | 2013-02-12 | Aker Biomarine Asa | Phospholipid and protein tablets |
| US20130295171A1 (en) | 2009-07-23 | 2013-11-07 | U.S NUTRACEUTICALS, LLC d/b/a Valensa International | Krill oil and reacted astaxanthin composition and associated method |
| US8586567B2 (en) * | 2009-10-29 | 2013-11-19 | Acasti Pharma, Inc. | Concentrated therapeutic phospholipid compositions |
| EP2493296B1 (en) | 2009-10-30 | 2019-01-09 | Retrotope, Inc. | Alleviating oxidative stress disorders with pufa derivatives |
| US20130115618A1 (en) * | 2010-02-11 | 2013-05-09 | Katholieke Universiteit Leuven | Phospholipid profiling and cancer |
| WO2011137160A2 (en) * | 2010-04-30 | 2011-11-03 | U.S. Nutraceuticals, Llc D/B/A Valensa International | Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (ldl) per-oxidation in humans |
| US9763897B2 (en) | 2010-04-30 | 2017-09-19 | U.S. Nutraceuticals, LLC | Therapeutic astaxanthin and phospholipid composition and associated method |
| US8663704B2 (en) | 2010-04-30 | 2014-03-04 | U.S. Nutraceuticals, LLC | Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans |
| RU2467334C2 (ru) * | 2010-08-24 | 2012-11-20 | Федеральное государственное бюджетное учреждение "Дальневосточный научный центр физиологии и патологии дыхания" Сибирского отделения РАМН | СПОСОБ ОЦЕНКИ МИКРОВЯЗКОСТИ МЕМБРАН ЭРИТРОЦИТОВ ПУТЕМ ВЫЧИСЛЕНИЯ КОЭФФИЦИЕНТА ЭКСИМЕРИЗАЦИИ ПИРЕНА Кэкс У БЕРЕМЕННЫХ, ПЕРЕНЕСШИХ ОБОСТРЕНИЕ ГЕРПЕС-ВИРУСНОЙ ИНФЕКЦИИ В ТРЕТЬЕМ ТРИМЕСТРЕ ГЕСТАЦИИ, С УЧЕТОМ ОПРЕДЕЛЕНИЯ ПРОЦЕНТНОГО СОДЕРЖАНИЯ ОЛЕИНОВОЙ КИСЛОТЫ В МЕМБРАНАХ ЭРИТРОЦИТОВ |
| GB201016139D0 (en) * | 2010-09-24 | 2010-11-10 | Univ Leuven Kath | Cancer phosholipidome |
| WO2012148930A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Oxidative retinal diseases |
| KR102020611B1 (ko) * | 2011-04-26 | 2019-09-10 | 레트로토프 인코포레이티드 | Pufa와 관련된 신경퇴행성 질환 및 근육 질환 |
| WO2012148929A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Disorders implicating pufa oxidation |
| EP3730135A1 (en) | 2011-04-26 | 2020-10-28 | Retrotope, Inc. | Impaired energy processing disorders and mitochondrial deficiency |
| US8846604B2 (en) | 2011-09-02 | 2014-09-30 | Artic Nutrition AS | Lipid compositions with high DHA content |
| PT2819649T (pt) * | 2012-02-29 | 2018-02-19 | Braun Melsungen Ag | Emulsão que contém hormona |
| RU2667968C2 (ru) * | 2012-03-02 | 2018-09-25 | Н.В. Нютрисиа | Способ улучшения функциональной синаптической связи |
| EP2825057B8 (en) | 2012-03-12 | 2020-06-24 | Innolipid As | Oxidixable fatty acid composition delivery form |
| WO2014045127A2 (en) | 2012-09-19 | 2014-03-27 | Aker Biomarine As | Omega-3 phospholipid supplements for females |
| US9295683B2 (en) | 2013-03-14 | 2016-03-29 | Aker Biomarine Antarctic As | Omega-3 phospholipid supplements for improved brain maturity |
| CN103242407A (zh) * | 2013-05-15 | 2013-08-14 | 张雅茹 | 含多不饱和脂肪酰基的磷脂酰甾醇和/或磷脂酰甾烷醇及制备方法和应用 |
| AU2014203179C1 (en) | 2013-06-14 | 2017-05-04 | Aker Biomarine Antarctic As | Lipid extraction processes |
| CN103609752B (zh) * | 2013-12-02 | 2016-05-25 | 内蒙古伊利实业集团股份有限公司 | 一种改善脑部认知功能的组合物及其制备方法与应用 |
| JP6291058B2 (ja) * | 2013-12-05 | 2018-03-14 | エンザイモテック リミティド | セリングリセロリン脂質調製物及び発作の治療方法 |
| GB201400431D0 (en) | 2014-01-10 | 2014-02-26 | Aker Biomarine As | Phospholipid compositions and their preparation |
| US10898525B2 (en) | 2014-04-30 | 2021-01-26 | Aker Biomarine Antarctic As | Krill oil preparations and their uses |
| US20170360812A1 (en) | 2014-11-20 | 2017-12-21 | Enzymotec Ltd. | Phospholipid preparations for the improvement of communication skills |
| EP3256003B2 (en) | 2015-02-11 | 2025-07-16 | Aker Biomarine Antarctic AS | Lipid extraction processes |
| KR102079747B1 (ko) | 2015-02-11 | 2020-02-20 | 에이커 바이오마린 앤탁틱 에이에스 | 지질 조성물 |
| US10894056B2 (en) * | 2015-07-13 | 2021-01-19 | Enzymotec Ltd | Phospholipid preparations for the improvement of sleep |
| KR102643910B1 (ko) | 2015-11-23 | 2024-03-06 | 레트로토프 인코포레이티드 | 1,4-다이엔 시스템에 대한 부위 특이적인 동위원소 표지법 |
| KR101744203B1 (ko) * | 2016-01-12 | 2017-06-20 | (주)노터스생명과학 | 포스파티딜콜린을 유효성분으로 포함하는 신장질환 예방 또는 치료용 약학 조성물 |
| WO2017153841A1 (en) | 2016-03-10 | 2017-09-14 | Enzymotec Ltd. | Phospholipid preparations for the improvement of brain plasticity |
| ES2663392B2 (es) * | 2016-05-17 | 2018-09-24 | Universidad De La Laguna | Complemento nutricional para la protección de neuronas frente al riesgo de Alzheimer y Parkinson en mujeres combinando isoflavonas y ácido docosahexaenoico. |
| WO2018060395A1 (en) | 2016-09-29 | 2018-04-05 | Nestec S.A. | Omega 3 fatty acids, no releasing compound and vitamin b12 as neuroprotectant in patients with no dementia |
| CN109793802A (zh) * | 2017-11-16 | 2019-05-24 | 西双版纳华坤生物科技有限责任公司 | 一种用于预防和治疗帕金森症的物质及制备方法和用途 |
| EP3747431A4 (en) * | 2018-01-31 | 2021-11-17 | Kinjirushi Co., Ltd. | RECOGNITION CAPACITY IMPROVING AGENT |
| US11679091B2 (en) | 2018-02-09 | 2023-06-20 | Nippon Suisan Kaisha, Ltd. | Lymphatic circulation improving agents |
| CN108721269A (zh) * | 2018-07-10 | 2018-11-02 | 广东海洋大学 | 一种epa与dha混合剂在防治焦虑和快感缺乏方面的应用 |
| KR20220143931A (ko) | 2020-02-21 | 2022-10-25 | 레트로토프 인코포레이티드 | 고도불포화 지방산 및 이의 유도체의 동위원소 변형을 위한 공정 |
| JP7539076B2 (ja) * | 2020-02-29 | 2024-08-23 | 国立大学法人九州大学 | α-グルコシダーゼ阻害剤 |
| JPWO2022050355A1 (pt) * | 2020-09-04 | 2022-03-10 | ||
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
| CN113749255B (zh) * | 2021-09-15 | 2022-11-29 | 江南大学 | 一种磷脂组合物在修复肌肉损伤的应用 |
| GR20220100576A (el) * | 2022-07-13 | 2024-02-09 | Σταυρουλα Κωνσταντινου Μπασακιδου | Βρωσιμα ελαια εμπλουτισμενα με θρεπτικα συστατικα για την ενισχυση της λειτουργιας του εγκεφαλου |
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| JPS54117034A (en) * | 1978-02-28 | 1979-09-11 | Nippon Shoji Kk | Treating agent for consciousness and perception motion disorder |
| JP2524217B2 (ja) * | 1988-04-18 | 1996-08-14 | マルハ株式会社 | 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤 |
| JPH0279311A (ja) * | 1988-09-14 | 1990-03-19 | Ngk Insulators Ltd | 電気設備の高電圧瑞末部における接地層先端部の電界緩和構造及びその形成方法 |
| JPH03188088A (ja) * | 1989-12-15 | 1991-08-16 | Ajinomoto Co Inc | 新規リゾホスファチジルセリン |
| JPH0717855A (ja) * | 1992-09-02 | 1995-01-20 | Maruha Corp | 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤、痴呆治療剤、または脳機能改善効果を有する機能性食品 |
| GB9301629D0 (en) * | 1993-01-27 | 1993-03-17 | Scotia Holdings Plc | Formulations containing unsaturated fatty acids |
| JP3467794B2 (ja) * | 1993-03-09 | 2003-11-17 | 日本油脂株式会社 | 学習能向上剤 |
| JPH06279311A (ja) * | 1993-03-26 | 1994-10-04 | Sagami Chem Res Center | プロテインキナーゼcアイソザイムの活性化剤 |
| US5925669A (en) * | 1994-03-22 | 1999-07-20 | Molecular/Structural Bio Technologies, Inc. | Carrier compositions for anti-neoplastic drugs |
| US5716614A (en) * | 1994-08-05 | 1998-02-10 | Molecular/Structural Biotechnologies, Inc. | Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier |
| AU2738497A (en) * | 1996-04-24 | 1997-11-12 | Brigham And Women's Hospital | Omega-3 fatty acids and omega-3 phosphatidylcholine in the treatment of bipolar disorder |
| US6344482B1 (en) * | 1997-04-23 | 2002-02-05 | Andrew L. Stoll | Omega-3 fatty acids in the treatment of bipolar disorder |
| FR2762993B1 (fr) * | 1997-05-06 | 1999-08-13 | Inst Rech Biolog Sa | Nouvelle utilisation de phospholipides d'origine animale en therapeutique et/ou dietetique |
| WO2000007577A2 (de) * | 1998-08-06 | 2000-02-17 | Wolfgang Stremmel | Phosphatidylcholin als arzneimittel mit schleimhautschützender wirkung |
| US20040213766A1 (en) * | 2002-11-27 | 2004-10-28 | Cedric Francois | Compositions and methods for treating transplants |
| IL158552A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Lipids containing omega-3 fatty acids |
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- 2004-10-21 BR BRPI0415744A patent/BRPI0415744B8/pt not_active IP Right Cessation
- 2004-10-21 JP JP2006536258A patent/JP2007509131A/ja active Pending
- 2004-10-21 EP EP04791827A patent/EP1689413A2/en not_active Withdrawn
- 2004-10-21 EP EP10180547.1A patent/EP2258377B1/en not_active Expired - Lifetime
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- 2004-10-21 AU AU2004282006A patent/AU2004282006C1/en not_active Expired
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| IL158552A0 (en) | 2004-05-12 |
| WO2005037848A3 (en) | 2005-05-26 |
| RU2362566C2 (ru) | 2009-07-27 |
| KR20060094526A (ko) | 2006-08-29 |
| IL174925A (en) | 2014-01-30 |
| KR101331658B1 (ko) | 2013-11-20 |
| JP2012211168A (ja) | 2012-11-01 |
| JP5835671B2 (ja) | 2015-12-24 |
| EP1689413A2 (en) | 2006-08-16 |
| AU2004282006A1 (en) | 2005-04-28 |
| CA2542504C (en) | 2014-01-07 |
| EP2258377B1 (en) | 2019-08-28 |
| WO2005037848A2 (en) | 2005-04-28 |
| BRPI0415744B1 (pt) | 2018-07-17 |
| IL174925A0 (en) | 2008-02-09 |
| KR20120115419A (ko) | 2012-10-17 |
| JP2007509131A (ja) | 2007-04-12 |
| CN1897955A (zh) | 2007-01-17 |
| AU2004282006C1 (en) | 2010-10-21 |
| RU2006116267A (ru) | 2007-12-10 |
| IL224977A (en) | 2014-09-30 |
| AU2004282006B2 (en) | 2010-04-15 |
| BRPI0415744B8 (pt) | 2021-05-25 |
| EP2258377A2 (en) | 2010-12-08 |
| CN103381172A (zh) | 2013-11-06 |
| EP2258377A3 (en) | 2011-10-05 |
| CA2542504A1 (en) | 2005-04-28 |
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