BRPI0415744B8 - uso de uma preparação lipídica contendo ácidos graxos ômega-3 e ômega-6, esta preparação, uso de glicerofosfolipídios, composição nutracêutica e artigo alimentar funcional - Google Patents

uso de uma preparação lipídica contendo ácidos graxos ômega-3 e ômega-6, esta preparação, uso de glicerofosfolipídios, composição nutracêutica e artigo alimentar funcional

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Publication number
BRPI0415744B8
BRPI0415744B8 BRPI0415744A BRPI0415744A BRPI0415744B8 BR PI0415744 B8 BRPI0415744 B8 BR PI0415744B8 BR PI0415744 A BRPI0415744 A BR PI0415744A BR PI0415744 A BRPI0415744 A BR PI0415744A BR PI0415744 B8 BRPI0415744 B8 BR PI0415744B8
Authority
BR
Brazil
Prior art keywords
omega
fatty acids
preparation
glycerophospholipids
pufa
Prior art date
Application number
BRPI0415744A
Other languages
English (en)
Inventor
Shulman Avidor
Pelled Dori
Platt Dorit
Ben Dror Gai
Farkash Orly
Zuabi Rassan
Bar-On Zohar
Original Assignee
Enzymotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enzymotec Ltd filed Critical Enzymotec Ltd
Publication of BRPI0415744A publication Critical patent/BRPI0415744A/pt
Publication of BRPI0415744B1 publication Critical patent/BRPI0415744B1/pt
Publication of BRPI0415744B8 publication Critical patent/BRPI0415744B8/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives

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Abstract

"lipídios contendo ácidos graxos ômega-3 e ômega-6". apresenta-se uma preparação lipídica compreendendo um glicerofosfolipídio ou seu sal, conjugado ou derivado, particularmente fosfaditilserina (ps), fosfatidilcolina (pc), fosfatidiletanolamina (pe), fosfatidilinositol (pi), fosfatidilglicerol (pg) e ácido fosfatídico (pa) e grupos acila de ácido graxo poliinsaturado (pufa), particularmente grupos acila de ácido graxo poliinsaturado de cadeia longa (lc-pufa), como grupos acila ômega-3 e/ou ômega-6, em que o dito pufa está covalentemente ligado ao dito glicerofosfolipídio. as preparações apresentadas possuem uma melhor bioatividade e são utilizáveis no tratamento de vários estados e distúrbios cognitivos e mentais e para a manutenção das funções normais de sistemas e processos relacionados ao cérebro.
BRPI0415744A 2003-10-22 2004-10-21 uso de uma preparação lipídica contendo ácidos graxos ômega-3 e ômega-6, esta preparação, uso de glicerofosfolipídios, composição nutracêutica e artigo alimentar funcional BRPI0415744B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15855203A IL158552A0 (en) 2003-10-22 2003-10-22 Lipids containing omega-3 fatty acids
PCT/IL2004/000957 WO2005037848A2 (en) 2003-10-22 2004-10-21 Glycerophospholipids containing omega-3 and omega-6 fatty acids

Publications (3)

Publication Number Publication Date
BRPI0415744A BRPI0415744A (pt) 2006-12-19
BRPI0415744B1 BRPI0415744B1 (pt) 2018-07-17
BRPI0415744B8 true BRPI0415744B8 (pt) 2021-05-25

Family

ID=34044222

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415744A BRPI0415744B8 (pt) 2003-10-22 2004-10-21 uso de uma preparação lipídica contendo ácidos graxos ômega-3 e ômega-6, esta preparação, uso de glicerofosfolipídios, composição nutracêutica e artigo alimentar funcional

Country Status (10)

Country Link
EP (2) EP1689413A2 (pt)
JP (2) JP2007509131A (pt)
KR (2) KR101331658B1 (pt)
CN (2) CN103381172A (pt)
AU (1) AU2004282006C1 (pt)
BR (1) BRPI0415744B8 (pt)
CA (1) CA2542504C (pt)
IL (3) IL158552A0 (pt)
RU (1) RU2362566C2 (pt)
WO (1) WO2005037848A2 (pt)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003048831A (ja) 2001-08-02 2003-02-21 Suntory Ltd 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物
IL158553A0 (en) * 2003-10-22 2004-05-12 Enzymotec Ltd Method for preparing phosphatidylserine containing omega-3 acid moieties
IL158552A0 (en) * 2003-10-22 2004-05-12 Enzymotec Ltd Lipids containing omega-3 fatty acids
US7935365B2 (en) * 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
JP4993852B2 (ja) 2004-09-17 2012-08-08 サントリーホールディングス株式会社 ストレスに起因する行動異常を伴う症状あるいは疾患の予防又は改善作用を有する組成物
JP5967855B2 (ja) 2005-06-30 2016-08-10 サントリーホールディングス株式会社 日中活動量の低下および／又はうつ症状の改善作用を有する組成物
JP5697293B2 (ja) * 2005-06-30 2015-04-08 サントリーホールディングス株式会社 器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する組成物
CA2645123A1 (en) * 2006-02-28 2007-09-07 Bristol-Myers Squibb Company Use of dha and ara in the preparation of a composition for regulating gene expression
JP2008260743A (ja) * 2006-08-03 2008-10-30 Nagase Chemtex Corp Ｎｑｏ１発現増強剤
JPWO2008081989A1 (ja) 2006-12-28 2010-04-30 サントリーホールディングス株式会社 神経再生剤
FI2144618T4 (fi) 2007-03-28 2025-02-13 Aker Biomarine Antarctic As Biovaikuttavat krilliöljykoostumukset
US8697138B2 (en) 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
RU2611808C2 (ru) * 2007-11-01 2017-03-01 Энзимотек Лтд. Липидная смесь для детского питания
US9085527B2 (en) 2008-07-08 2015-07-21 Catabasis Pharmaceuticals, Inc. Fatty acid acylated salicylates and their uses
US8372812B2 (en) 2009-02-26 2013-02-12 Aker Biomarine Asa Phospholipid and protein tablets
US20130295171A1 (en) 2009-07-23 2013-11-07 U.S NUTRACEUTICALS, LLC d/b/a Valensa International Krill oil and reacted astaxanthin composition and associated method
JP5827625B2 (ja) 2009-10-29 2015-12-02 アカスティ ファーマ インコーポレイテッド 濃縮治療用リン脂質組成物
JP5934102B2 (ja) 2009-10-30 2016-06-15 レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． Ｐｕｆａ誘導体による酸化ストレス障害の緩和
SG183220A1 (en) * 2010-02-11 2012-09-27 Univ Leuven Kath Phospholipid profiling and cancer
WO2011137160A2 (en) * 2010-04-30 2011-11-03 U.S. Nutraceuticals, Llc D/B/A Valensa International Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (ldl) per-oxidation in humans
US9763897B2 (en) 2010-04-30 2017-09-19 U.S. Nutraceuticals, LLC Therapeutic astaxanthin and phospholipid composition and associated method
US8663704B2 (en) 2010-04-30 2014-03-04 U.S. Nutraceuticals, LLC Composition and method to improve blood lipid profiles and optionally reduce low density lipoprotein (LDL) per-oxidation in humans
RU2467334C2 (ru) * 2010-08-24 2012-11-20 Федеральное государственное бюджетное учреждение "Дальневосточный научный центр физиологии и патологии дыхания" Сибирского отделения РАМН СПОСОБ ОЦЕНКИ МИКРОВЯЗКОСТИ МЕМБРАН ЭРИТРОЦИТОВ ПУТЕМ ВЫЧИСЛЕНИЯ КОЭФФИЦИЕНТА ЭКСИМЕРИЗАЦИИ ПИРЕНА Кэкс У БЕРЕМЕННЫХ, ПЕРЕНЕСШИХ ОБОСТРЕНИЕ ГЕРПЕС-ВИРУСНОЙ ИНФЕКЦИИ В ТРЕТЬЕМ ТРИМЕСТРЕ ГЕСТАЦИИ, С УЧЕТОМ ОПРЕДЕЛЕНИЯ ПРОЦЕНТНОГО СОДЕРЖАНИЯ ОЛЕИНОВОЙ КИСЛОТЫ В МЕМБРАНАХ ЭРИТРОЦИТОВ
GB201016139D0 (en) * 2010-09-24 2010-11-10 Univ Leuven Kath Cancer phosholipidome
CA2834342C (en) 2011-04-26 2021-08-31 Retrotope, Inc. Impaired energy processing disorders and mitochondrial deficiency
KR102110175B1 (ko) 2011-04-26 2020-05-13 레트로토프 인코포레이티드 Ｐｕｆａ 산화와 관련된 장애
WO2012148926A2 (en) 2011-04-26 2012-11-01 Retrotope, Inc. Neurodegenerative disorders and muscle diseases implicating pufas
AU2012249921B2 (en) 2011-04-26 2017-06-08 Biojiva Llc Oxidative retinal diseases
US8846604B2 (en) 2011-09-02 2014-09-30 Artic Nutrition AS Lipid compositions with high DHA content
IN2014DN08088A (pt) 2012-02-29 2015-05-01 Braun Melsungen Ag
US20150044138A1 (en) * 2012-03-02 2015-02-12 N.V. Nutricia Method for improving functional synaptic connectivity
EP2825057B8 (en) 2012-03-12 2020-06-24 Innolipid As Oxidixable fatty acid composition delivery form
WO2014045127A2 (en) 2012-09-19 2014-03-27 Aker Biomarine As Omega-3 phospholipid supplements for females
AU2014229540A1 (en) 2013-03-14 2015-10-08 Aker Biomarine Antarctic As Omega- 3 phospholipid supplements for improved brain maturity
CN103242407A (zh) * 2013-05-15 2013-08-14 张雅茹 含多不饱和脂肪酰基的磷脂酰甾醇和/或磷脂酰甾烷醇及制备方法和应用
AU2014203179C1 (en) 2013-06-14 2017-05-04 Aker Biomarine Antarctic As Lipid extraction processes
CN103609752B (zh) * 2013-12-02 2016-05-25 内蒙古伊利实业集团股份有限公司 一种改善脑部认知功能的组合物及其制备方法与应用
US10688070B2 (en) 2013-12-05 2020-06-23 Enzymotec Ltd. Serine glycerophospholipid preparation and method for treatment of seizures
GB201400431D0 (en) 2014-01-10 2014-02-26 Aker Biomarine As Phospholipid compositions and their preparation
CN106535650A (zh) 2014-04-30 2017-03-22 恩兹莫特克有限公司 磷虾油制剂和它们的用途
JP6787891B2 (ja) * 2014-11-20 2020-11-18 エンザイモテック リミティド コミュニケーションスキルの改善のためのリン脂質調製物
NZ735362A (en) 2015-02-11 2019-01-25 Aker Biomarine Antarctic As Lipid compositions
PL3256003T5 (pl) 2015-02-11 2025-11-17 Aker Biomarine Human Ingredients As Sposoby ekstrakcji lipidów
WO2017009711A1 (en) * 2015-07-13 2017-01-19 Enzymotec Ltd. Phospholipid preparations for the improvement of sleep
EP3380452B1 (en) 2015-11-23 2021-03-24 Retrotope, Inc. Site-specific isotopic labeling of 1, 4-diene systems
KR101744203B1 (ko) * 2016-01-12 2017-06-20 (주)노터스생명과학 포스파티딜콜린을 유효성분으로 포함하는 신장질환 예방 또는 치료용 약학 조성물
US10888573B2 (en) 2016-03-10 2021-01-12 Enzymotec Ltd. Phospholipid preparations for the improvement of brain plasticity
ES2663392B2 (es) * 2016-05-17 2018-09-24 Universidad De La Laguna Complemento nutricional para la protección de neuronas frente al riesgo de Alzheimer y Parkinson en mujeres combinando isoflavonas y ácido docosahexaenoico.
JP7523905B2 (ja) * 2016-09-29 2024-07-29 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 認知症でない患者における神経保護薬としての、ω３脂肪酸、一酸化窒素放出化合物及びビタミンＢ１２
CN109793802A (zh) * 2017-11-16 2019-05-24 西双版纳华坤生物科技有限责任公司 一种用于预防和治疗帕金森症的物质及制备方法和用途
EP3747431A4 (en) * 2018-01-31 2021-11-17 Kinjirushi Co., Ltd. RECOGNITION CAPACITY IMPROVING AGENT
EP3750533A4 (en) * 2018-02-09 2021-11-03 Nippon Suisan Kaisha, Ltd. MEANS TO IMPROVE LYMPH CIRCULATION
CN108721269A (zh) * 2018-07-10 2018-11-02 广东海洋大学 一种epa与dha混合剂在防治焦虑和快感缺乏方面的应用
US11779910B2 (en) 2020-02-21 2023-10-10 Biojiva Llc Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof
JP7539076B2 (ja) * 2020-02-29 2024-08-23 国立大学法人九州大学 α－グルコシダーゼ阻害剤
JPWO2022050355A1 (pt) * 2020-09-04 2022-03-10
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS
CN113749255B (zh) * 2021-09-15 2022-11-29 江南大学 一种磷脂组合物在修复肌肉损伤的应用
GR20220100576A (el) * 2022-07-13 2024-02-09 Σταυρουλα Κωνσταντινου Μπασακιδου Βρωσιμα ελαια εμπλουτισμενα με θρεπτικα συστατικα για την ενισχυση της λειτουργιας του εγκεφαλου

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54117034A (en) * 1978-02-28 1979-09-11 Nippon Shoji Kk Treating agent for consciousness and perception motion disorder
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
JPH0279311A (ja) * 1988-09-14 1990-03-19 Ngk Insulators Ltd 電気設備の高電圧瑞末部における接地層先端部の電界緩和構造及びその形成方法
JPH03188088A (ja) * 1989-12-15 1991-08-16 Ajinomoto Co Inc 新規リゾホスファチジルセリン
JPH0717855A (ja) * 1992-09-02 1995-01-20 Maruha Corp 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤、痴呆治療剤、または脳機能改善効果を有する機能性食品
GB9301629D0 (en) * 1993-01-27 1993-03-17 Scotia Holdings Plc Formulations containing unsaturated fatty acids
JP3467794B2 (ja) * 1993-03-09 2003-11-17 日本油脂株式会社 学習能向上剤
JPH06279311A (ja) * 1993-03-26 1994-10-04 Sagami Chem Res Center プロテインキナーゼｃアイソザイムの活性化剤
US5925669A (en) * 1994-03-22 1999-07-20 Molecular/Structural Bio Technologies, Inc. Carrier compositions for anti-neoplastic drugs
US5716614A (en) * 1994-08-05 1998-02-10 Molecular/Structural Biotechnologies, Inc. Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier
AU2738497A (en) * 1996-04-24 1997-11-12 Brigham And Women's Hospital Omega-3 fatty acids and omega-3 phosphatidylcholine in the treatment of bipolar disorder
US6344482B1 (en) * 1997-04-23 2002-02-05 Andrew L. Stoll Omega-3 fatty acids in the treatment of bipolar disorder
FR2762993B1 (fr) * 1997-05-06 1999-08-13 Inst Rech Biolog Sa Nouvelle utilisation de phospholipides d'origine animale en therapeutique et/ou dietetique
US6677319B1 (en) * 1998-08-06 2004-01-13 Wolfgang Stremmel Phosphatidylcholine as medication with protective effect large intestinal mucosa
WO2004049907A2 (en) * 2002-11-27 2004-06-17 University Of Louisville Research Foundation Compositions and methods for treating transplants
IL158552A0 (en) * 2003-10-22 2004-05-12 Enzymotec Ltd Lipids containing omega-3 fatty acids

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EP2258377A3 (en) 2011-10-05
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