BRPI0409890A - processo para a produção de um gel de polissacarìdeo reticulado, gel de polissacarìdeo reticulado substancialmente resistente à degradação de hialuronidase, composição farmacêutica, método para o tratamento ou a prevenção de um distúrbio ou uma condição selecionada do grupo que consiste em aumento de tecido, artrite, aderências de tecidos, capacidade imunogênica, doenças da mucosa, condições dermatológicas, condições oftalmológicas, condições hormonais, condições de lubrificação das juntas e condições cosméticas, em um indivìduo com necessidade do mesmo e uso de um gel - Google Patents

processo para a produção de um gel de polissacarìdeo reticulado, gel de polissacarìdeo reticulado substancialmente resistente à degradação de hialuronidase, composição farmacêutica, método para o tratamento ou a prevenção de um distúrbio ou uma condição selecionada do grupo que consiste em aumento de tecido, artrite, aderências de tecidos, capacidade imunogênica, doenças da mucosa, condições dermatológicas, condições oftalmológicas, condições hormonais, condições de lubrificação das juntas e condições cosméticas, em um indivìduo com necessidade do mesmo e uso de um gel

Info

Publication number
BRPI0409890A
BRPI0409890A BRPI0409890-0A BRPI0409890A BRPI0409890A BR PI0409890 A BRPI0409890 A BR PI0409890A BR PI0409890 A BRPI0409890 A BR PI0409890A BR PI0409890 A BRPI0409890 A BR PI0409890A
Authority
BR
Brazil
Prior art keywords
conditions
cross
gel
linked polysaccharide
tissue
Prior art date
Application number
BRPI0409890-0A
Other languages
English (en)
Inventor
Simone Charlotte Vonwiller
Geoffrey Kenneth Heber
Original Assignee
Ultraceuticals R & D Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ultraceuticals R & D Pty Ltd filed Critical Ultraceuticals R & D Pty Ltd
Publication of BRPI0409890A publication Critical patent/BRPI0409890A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

"PROCESSO PARA A PRODUçãO DE UM GEL DE POLISSACARìDEO RETICULADO, GEL DE POLISSACARìDEO RETICULADO SUBSTANCIALMENTE RESISTENTE A DEGRADAçãO DE HIALURONIDASE, COMPOSIçãO FARMACêUTICA, MéTODO PARA O TRATAMENTO OU A PREVENçãO DE UM DISTúRBIO OU UMA CONDIçãO SELECIONADA DO GRUPO QUE CONSISTE EM AUMENTO DE TECIDO, ARTRITE, ADERêNCIAS DE TECIDOS, CAPACIDADE IMUNOGêNICA, DOENçAS DA MUCOSA, CONDIçõES DERMATOLóGICAS, CONDIçõES OFTALMOLóGICAS, CONDIçõES HORMONAIS, CONDIçõES DE LUBRIFICAçãO DAS JUNTAS E CONDIçõES COSMéTICAS, EM UM INDIVìDUO COM NECESSIDADE DO MESMO E USO DE UM GEL". A presente invenção apresenta um processo para a produção de géis de polissacarídeo reticulado sob condições básicas. Mais particularmente, a presente invenção apresenta um processo para a formação de géis de ácido hialurónico reticulados sob condições básicas. Os géis resultantes possuem características melhoradas de degradação, e são úteis em uma variedade de aplicações médicas e cosméticas.
BRPI0409890-0A 2003-04-17 2004-04-16 processo para a produção de um gel de polissacarìdeo reticulado, gel de polissacarìdeo reticulado substancialmente resistente à degradação de hialuronidase, composição farmacêutica, método para o tratamento ou a prevenção de um distúrbio ou uma condição selecionada do grupo que consiste em aumento de tecido, artrite, aderências de tecidos, capacidade imunogênica, doenças da mucosa, condições dermatológicas, condições oftalmológicas, condições hormonais, condições de lubrificação das juntas e condições cosméticas, em um indivìduo com necessidade do mesmo e uso de um gel BRPI0409890A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2003901834A AU2003901834A0 (en) 2003-04-17 2003-04-17 Cross-linked polysaccharide compositions
PCT/AU2004/000509 WO2004092223A1 (en) 2003-04-17 2004-04-16 Cross-linked polysaccharide composition

Publications (1)

Publication Number Publication Date
BRPI0409890A true BRPI0409890A (pt) 2006-05-23

Family

ID=31500871

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409890-0A BRPI0409890A (pt) 2003-04-17 2004-04-16 processo para a produção de um gel de polissacarìdeo reticulado, gel de polissacarìdeo reticulado substancialmente resistente à degradação de hialuronidase, composição farmacêutica, método para o tratamento ou a prevenção de um distúrbio ou uma condição selecionada do grupo que consiste em aumento de tecido, artrite, aderências de tecidos, capacidade imunogênica, doenças da mucosa, condições dermatológicas, condições oftalmológicas, condições hormonais, condições de lubrificação das juntas e condições cosméticas, em um indivìduo com necessidade do mesmo e uso de um gel

Country Status (13)

Country Link
US (2) US20070026070A1 (pt)
EP (1) EP1613663B1 (pt)
JP (2) JP2006523731A (pt)
KR (1) KR20060008906A (pt)
CN (1) CN100509858C (pt)
AT (1) ATE476450T1 (pt)
AU (1) AU2003901834A0 (pt)
BR (1) BRPI0409890A (pt)
CA (1) CA2522232C (pt)
DE (1) DE602004028455D1 (pt)
ES (1) ES2349924T3 (pt)
MX (1) MXPA05011098A (pt)
WO (1) WO2004092223A1 (pt)

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DE602004028455D1 (de) 2010-09-16
ATE476450T1 (de) 2010-08-15
ES2349924T3 (es) 2011-01-13
KR20060008906A (ko) 2006-01-27
EP1613663B1 (en) 2010-08-04
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