RU2016146372A - Комбинация гиалуроновой кислоты и сульфатированного полисахарида - Google Patents
Комбинация гиалуроновой кислоты и сульфатированного полисахарида Download PDFInfo
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- RU2016146372A RU2016146372A RU2016146372A RU2016146372A RU2016146372A RU 2016146372 A RU2016146372 A RU 2016146372A RU 2016146372 A RU2016146372 A RU 2016146372A RU 2016146372 A RU2016146372 A RU 2016146372A RU 2016146372 A RU2016146372 A RU 2016146372A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Claims (16)
1. Комбинация, содержащая гиалуроновую кислоту или ее соль и сульфатированный полисахарид, имеющий молекулярную массу в диапазоне от 5 до 25 кДа, выбранный из сульфатированных фуканов и сульфатированных ульванов.
2. Комбинация по п. 1, отличающаяся тем, что гиалуроновая кислота или ее соль имеет средневесовую молекулярную массу в диапазоне от 50 до 750 кДа.
3. Комбинация по п. 2, отличающаяся тем, что указанная средневесовая молекулярная масса составляет от 60 до 120 кДа.
4. Комбинация по п. 1, отличающаяся тем, что сульфатированный полисахарид, имеющий молекулярную массу в диапазоне от 5 до 25 кДа, представляет собой сульфатированный фукан.
5. Комбинация по п. 1, отличающаяся тем, что массовое отношение гиалуроновой кислоты к полисахариду составляет от 0,1 до 10.
6. Комбинация по любому из пп. 1-5 для местного применения для стимуляции пролиферации фибробластов.
7. Местное применение комбинации по любому из пп. 1-5 для борьбы с признаками старения кожи.
8. Комбинация по любому из пп. 1-5 для местного применения для лечения повреждений кожи.
9. Комбинация по любому из пп. 1-5 для местного применения для улучшения заживления и восстановления кожи.
10. Дерматологическая или косметическая композиция, содержащая в качестве активного ингредиента комбинацию по любому из пп. 1-5 с по меньшей мере одним дерматологически или косметически приемлемым эксципиентом.
11. Композиция по п. 10, отличающаяся тем, что она дополнительно содержит другой активный ингредиент.
12. Композиция по п. 11, отличающаяся тем, что другой активный ингредиент выбран из агентов, предотвращающий старение, заживляющих агентов, смягчающих агентов, противозудных агентов, агентов против радикалов, агентов против УФ-излучения, агентов, стимулирующих синтез дермальных макромолекул или энергетический метаболизм, увлажняющих агентов, депигментирующих агентов, антибактериальных агентов, противогрибковых средств, противовоспалительных средств, анестетиков или их смесей.
13. Композиция по п. 11, отличающаяся тем, что другой активный ингредиент представляет собой ретинальдегид.
14. Композиция по п. 11, отличающаяся тем, что другой активный ингредиент представляет собой дельта-токоферилглюкопиранозид.
15. Косметическое применение косметической композиции по любому из пп. 10-14 для борьбы с признаками старения кожи.
16. Дерматологическая композиция по п. 10 для применения в лечении порезов, швов, ссадин, царапин, соскобов, рубцов после хирургической операции или после эстетической дерматологической процедуры, поверхностных ожогов, солнечных ожогов.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1453973A FR3020570B1 (fr) | 2014-04-30 | 2014-04-30 | Association d'un acide hyaluronique et d'un polysaccharide sulfate |
| FR1453973 | 2014-04-30 | ||
| PCT/EP2015/059544 WO2015166063A1 (fr) | 2014-04-30 | 2015-04-30 | Association d'un acide hyaluronique et d'un polysaccharide sulfate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016146372A true RU2016146372A (ru) | 2018-05-31 |
| RU2016146372A3 RU2016146372A3 (ru) | 2018-10-03 |
| RU2683567C2 RU2683567C2 (ru) | 2019-03-29 |
Family
ID=50976947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016146372A RU2683567C2 (ru) | 2014-04-30 | 2015-04-30 | Комбинация гиалуроновой кислоты и сульфатированного полисахарида |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9993417B2 (ru) |
| EP (1) | EP3137050B1 (ru) |
| JP (1) | JP6625558B2 (ru) |
| KR (1) | KR20160145788A (ru) |
| CN (1) | CN106255490B (ru) |
| AU (1) | AU2015254602B2 (ru) |
| BR (1) | BR112016024161B1 (ru) |
| CA (1) | CA2946943C (ru) |
| FR (1) | FR3020570B1 (ru) |
| MX (1) | MX2016014050A (ru) |
| RU (1) | RU2683567C2 (ru) |
| WO (1) | WO2015166063A1 (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038355B (zh) * | 2016-07-21 | 2019-11-12 | 中国科学院海洋研究所 | 一种高硫酸化的海藻多糖在晒后修复面膜中的应用 |
| JPWO2019022250A1 (ja) * | 2017-07-28 | 2020-07-09 | 国立大学法人九州大学 | 水溶性有効成分の放出が制御された経皮吸収組成物 |
| FR3075644B1 (fr) * | 2017-12-27 | 2020-08-28 | Oreal | Oligosaccharides sulfates et leurs utilisations cosmetiques |
| CN108553481B (zh) * | 2018-05-25 | 2020-11-13 | 中国海洋大学 | 一种具有促进伤口愈合作用的糖类组合物及其应用 |
| US11628183B2 (en) * | 2018-07-27 | 2023-04-18 | ARC Medical Ine. | Highly purified fucans for the treatment of fibrous adhesions |
| FR3098723B1 (fr) * | 2019-07-18 | 2023-01-13 | Bionuclei | Traitement ecobiologique des effets secondaires de la radiotherapie. |
| RU2753638C2 (ru) * | 2020-01-24 | 2021-08-18 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НОВАСКИН" (ООО "Новаскин") | Гелевая композиция для обработки кожных покровов |
| FR3113236A1 (fr) * | 2020-08-05 | 2022-02-11 | Algues Et Mer | Fraction purifiée de fucoïdanes pour la préparation de compositions cosmétiques et/ou dermatologiques anti-age. |
| IT202000022477A1 (it) * | 2020-09-23 | 2022-03-23 | Sofar Swiss Sa | Composizioni comprendenti una condroitina vegetale o un suo analogo e loro uso nel trattamento disturbi della mucosa del tratto orale, faringo-laringeo e/o gastro-esofageo |
| CN115040535B (zh) * | 2022-08-15 | 2022-12-16 | 华南理工大学 | 硫酸化透明质酸在制备预防角膜纤维化、角膜瘢痕滴眼液中的应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IT1212892B (it) * | 1983-10-11 | 1989-11-30 | Della Valle Francesco | Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica |
| EP0778776A1 (en) * | 1994-08-30 | 1997-06-18 | Hyal Pharmaceutical Corporation | Hyaluronic acid and derivatives for modulation of cellular activity |
| FR2772618B1 (fr) * | 1997-12-18 | 2000-02-18 | Ifremer | Utilisation de fucane comme regulateur de la reconstruction des tissus conjonctifs |
| FR2775976B1 (fr) * | 1998-03-10 | 2000-06-02 | Fabre Pierre Dermo Cosmetique | Composition pharmaceutique ou cosmetique contenant un precurseur d'actif hydrolysable par la glucocerebrosidase |
| US6572868B1 (en) * | 2000-07-25 | 2003-06-03 | Sandra E. Cope | Restructuring complex for cosmetic compositions |
| FR2829762B1 (fr) * | 2001-09-17 | 2004-02-13 | Fabre Pierre Dermo Cosmetique | Bioprecurseurs destines a une application percutanee |
| KR100485326B1 (ko) * | 2002-12-26 | 2005-04-27 | 주식회사 태평양 | 진세노사이드 화합물 ｋ로 이루어진 히알루론산 생성촉진제 |
| US6925626B2 (en) * | 2003-08-13 | 2005-08-02 | Lsi Logic Corporation | Method of routing a redistribution layer trace in an integrated circuit die |
| FR2865651B1 (fr) * | 2004-01-29 | 2007-09-28 | Fabre Pierre Dermo Cosmetique | Compositions topiques associant des fragments de hyaluronate de sodium et un retinoide utiles en dermatologie cosmetique et medicale |
| US20060040894A1 (en) * | 2004-08-13 | 2006-02-23 | Angiotech International Ag | Compositions and methods using hyaluronic acid |
| US20080038780A1 (en) | 2006-02-15 | 2008-02-14 | Novozymes Biopolymer A/S | Production of low molecular weight hyaluronic acid |
| FR2909560B1 (fr) | 2006-12-06 | 2012-12-28 | Fabre Pierre Dermo Cosmetique | Gel d'acide hyaluronique pour injection intradermique |
| DE102006060953A1 (de) * | 2006-12-12 | 2008-08-07 | Farco-Pharma Gmbh | Pharmazeutische Zubereitung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes |
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| JP5468757B2 (ja) * | 2007-09-04 | 2014-04-09 | ロート製薬株式会社 | 線維芽細胞増殖促進能を有する組成物 |
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| US7932237B2 (en) * | 2008-05-15 | 2011-04-26 | Consejo Nacional De Investigaciones Cientificas Y Technicas (CONICET) | Pharmaceutical compositions for use in the treatment of wounds |
| KR20100025237A (ko) * | 2008-08-27 | 2010-03-09 | 주식회사 해림후코이단 | 후코이단을 함유하는 아토피성 피부용 보습제 |
| WO2010086696A1 (en) | 2009-01-28 | 2010-08-05 | Therapol | Low-molecular-weight sulphated polysaccharides as candidates for anti-angiogenic therapy |
| KR101149711B1 (ko) * | 2010-02-25 | 2012-06-08 | (주)코스비전 | 저분자 후코이단, 비타민나무 추출물 및 니아신아마이드가 함유된 피부 미백용 화장료 조성물 및 그 제조방법 |
| US9629856B2 (en) * | 2010-03-03 | 2017-04-25 | Anteis Sa | Compositions and methods for the treatment of skin diseases and disorders using antimicrobial peptide sequestering compounds |
| FR2958157B1 (fr) * | 2010-04-02 | 2012-06-29 | Libragen | Composition cosmetique et pharmaceutique comprenant du n-acetyl-glucosamine-6-phosphate |
| FR2978664B1 (fr) * | 2011-08-04 | 2014-01-10 | Petcare Innovation | Composition antiseptique |
| JP5946253B2 (ja) * | 2011-08-10 | 2016-07-06 | ロート製薬株式会社 | 弾性線維形成促進剤 |
| FR2988606B1 (fr) * | 2012-03-30 | 2014-08-08 | Sederma Sa | Composition topique comprenant des oligosaccharides sulfates bioactifs et utilisations cosmetiques |
| FR2989087B1 (fr) * | 2012-04-06 | 2016-01-01 | Greentech | Nouveaux composes oligosaccharides et leur utilisation cosmetique |
-
2014
- 2014-04-30 FR FR1453973A patent/FR3020570B1/fr active Active
-
2015
- 2015-04-30 BR BR112016024161-4A patent/BR112016024161B1/pt active IP Right Grant
- 2015-04-30 US US15/307,681 patent/US9993417B2/en active Active
- 2015-04-30 MX MX2016014050A patent/MX2016014050A/es active IP Right Grant
- 2015-04-30 CN CN201580023077.3A patent/CN106255490B/zh active Active
- 2015-04-30 KR KR1020167032484A patent/KR20160145788A/ko not_active Application Discontinuation
- 2015-04-30 AU AU2015254602A patent/AU2015254602B2/en active Active
- 2015-04-30 CA CA2946943A patent/CA2946943C/fr active Active
- 2015-04-30 JP JP2016565157A patent/JP6625558B2/ja active Active
- 2015-04-30 EP EP15718939.0A patent/EP3137050B1/fr active Active
- 2015-04-30 RU RU2016146372A patent/RU2683567C2/ru active
- 2015-04-30 WO PCT/EP2015/059544 patent/WO2015166063A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| FR3020570B1 (fr) | 2017-07-21 |
| CN106255490A (zh) | 2016-12-21 |
| US20170049678A1 (en) | 2017-02-23 |
| EP3137050A1 (fr) | 2017-03-08 |
| BR112016024161B1 (pt) | 2021-03-02 |
| MX2016014050A (es) | 2017-02-14 |
| CA2946943A1 (fr) | 2015-11-05 |
| RU2683567C2 (ru) | 2019-03-29 |
| AU2015254602B2 (en) | 2019-10-24 |
| RU2016146372A3 (ru) | 2018-10-03 |
| US9993417B2 (en) | 2018-06-12 |
| CN106255490B (zh) | 2019-10-01 |
| JP6625558B2 (ja) | 2019-12-25 |
| CA2946943C (fr) | 2022-06-21 |
| WO2015166063A1 (fr) | 2015-11-05 |
| EP3137050B1 (fr) | 2020-03-04 |
| FR3020570A1 (fr) | 2015-11-06 |
| KR20160145788A (ko) | 2016-12-20 |
| JP2017514825A (ja) | 2017-06-08 |
| AU2015254602A1 (en) | 2016-12-22 |
| BR112016024161A2 (pt) | 2017-08-15 |
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