BR9811381A - Processos para tratar um organismo de mamìfero para se obter um desejado efeito fisiológico ou farmacológico local ou sistêmico, para tratar um organismo de mamìfero quanto a retinite de citomegalovìrus, para fornecer administração controlada e prolongada de um agente eficaz na obtenção de um desejado efeito fisiológico ou farmacológico local ou sistêmico, e, sistema de aplicação de medicamento de liberação prolongada - Google Patents

Processos para tratar um organismo de mamìfero para se obter um desejado efeito fisiológico ou farmacológico local ou sistêmico, para tratar um organismo de mamìfero quanto a retinite de citomegalovìrus, para fornecer administração controlada e prolongada de um agente eficaz na obtenção de um desejado efeito fisiológico ou farmacológico local ou sistêmico, e, sistema de aplicação de medicamento de liberação prolongada

Info

Publication number
BR9811381A
BR9811381A BR9811381-0A BR9811381A BR9811381A BR 9811381 A BR9811381 A BR 9811381A BR 9811381 A BR9811381 A BR 9811381A BR 9811381 A BR9811381 A BR 9811381A
Authority
BR
Brazil
Prior art keywords
coating layer
mammalian organism
local
treating
systemic
Prior art date
Application number
BR9811381-0A
Other languages
English (en)
Inventor
Jianbing Chen
Paul Ashton
Original Assignee
Control Delivery Sys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Control Delivery Sys Inc filed Critical Control Delivery Sys Inc
Publication of BR9811381A publication Critical patent/BR9811381A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • AIDS & HIV (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

"PROCESSOS PARA TRATAR UM ORGANISMO DE MAMìFERO PARA SE OBTER UM DESEJADO EFEITO FISIOLóGICO OU FARMACOLóGICO LOCAL OU SISTêMICO, PARA TRATAR UM ORGANISMO DE MAMìFERO QUANTO A RETINITE DE CITOMEGALOVìRUS, PARA FORNECER ADMINISTRAçãO CONTROLADA E PROLONGADA DE UM AGENTE EFICAZ NA OBTENçãO DE UM DESEJADO EFEITO FISIOLóGICO OU FARMACOLóGICO LOCAL OU SISTêMICO, E, SISTEMA DE APLICAçãO DE MEDICAMENTO DE LIBERAçãO PROLONGADA" Um processo e dispositivo para tratar um organismo de mamifero para se obter um efeito fisiológico ou farmacológico local ou sistêmico desejado é fornecido. O processo inclui administrar um sistema de aplicação de medicamento de liberação prolongada a um organismo de mamífero em necessidade de tal tratamento em uma área em que a aplicação de um agente eficaz é desejada e deixar o agente eficaz passar através do dispositivo de uma maneira controlada. O dispositivo inclui um núcleo interno ou reservatório que compreende o agente eficaz; uma primeira camada de revestimento, que é permeável à passagem do agente eficaz; uma segunda camada de revestimento, que é essencialmente impermeável à passagem do agente eficaz e uma terceira camada de revestimento, que é permeável à passagem do agente eficaz. A primeira camada de revestimento abrange pelo menos uma porção do núcleo interno. A segunda camada de revestimento abrange pelo menos uma porção da primeira camada de revestimento e o núcleo interno; entretanto, pelo menos uma pequena porção da primeira camada de revestimento ou do núcleo interno não é revestida com a segunda camada de revestimento. A segunda de revestimento inclui uma película impermeável e pelo menos um disco impermeável. A terceira camada de revestimento essencial e completamente cobre a segunda camada de revestimento e a porção não revestida da primeira camada de revestimentio ou do núcleo interno.
BR9811381-0A 1997-08-28 1998-08-28 Processos para tratar um organismo de mamìfero para se obter um desejado efeito fisiológico ou farmacológico local ou sistêmico, para tratar um organismo de mamìfero quanto a retinite de citomegalovìrus, para fornecer administração controlada e prolongada de um agente eficaz na obtenção de um desejado efeito fisiológico ou farmacológico local ou sistêmico, e, sistema de aplicação de medicamento de liberação prolongada BR9811381A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/919,221 US5902598A (en) 1997-08-28 1997-08-28 Sustained release drug delivery devices
PCT/US1998/017342 WO1999011244A1 (en) 1997-08-28 1998-08-28 Sustained release drug delivery devices

Publications (1)

Publication Number Publication Date
BR9811381A true BR9811381A (pt) 2000-08-29

Family

ID=25441727

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9811381-0A BR9811381A (pt) 1997-08-28 1998-08-28 Processos para tratar um organismo de mamìfero para se obter um desejado efeito fisiológico ou farmacológico local ou sistêmico, para tratar um organismo de mamìfero quanto a retinite de citomegalovìrus, para fornecer administração controlada e prolongada de um agente eficaz na obtenção de um desejado efeito fisiológico ou farmacológico local ou sistêmico, e, sistema de aplicação de medicamento de liberação prolongada

Country Status (25)

Country Link
US (1) US5902598A (pt)
EP (1) EP1009388B1 (pt)
JP (2) JP4530531B2 (pt)
KR (1) KR20010023358A (pt)
CN (2) CN100453074C (pt)
AR (1) AR017026A1 (pt)
AT (1) ATE548029T1 (pt)
AU (1) AU741846B2 (pt)
BR (1) BR9811381A (pt)
CA (1) CA2301685C (pt)
CZ (1) CZ302339B6 (pt)
EA (1) EA002162B1 (pt)
HK (1) HK1035135A1 (pt)
HU (1) HUP0002797A3 (pt)
IL (1) IL134568A (pt)
ME (2) ME00122B (pt)
NO (1) NO327752B1 (pt)
NZ (2) NZ502836A (pt)
PL (1) PL344039A1 (pt)
RS (1) RS52096B (pt)
SG (1) SG121718A1 (pt)
TR (1) TR200001029T2 (pt)
TW (1) TWI222884B (pt)
UA (1) UA71898C2 (pt)
WO (1) WO1999011244A1 (pt)

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AU741846B2 (en) 2001-12-13
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HUP0002797A2 (hu) 2001-01-29
TWI222884B (en) 2004-11-01
EP1009388A1 (en) 2000-06-21
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CN1283992A (zh) 2001-02-14
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EA200000267A1 (ru) 2000-10-30
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