BR9809651A - Processo para a fabricação de pastilhas de flurbiprofen de forma losangular - Google Patents

Processo para a fabricação de pastilhas de flurbiprofen de forma losangular

Info

Publication number
BR9809651A
BR9809651A BR9809651-6A BR9809651A BR9809651A BR 9809651 A BR9809651 A BR 9809651A BR 9809651 A BR9809651 A BR 9809651A BR 9809651 A BR9809651 A BR 9809651A
Authority
BR
Brazil
Prior art keywords
flurbiprofen
manufacturing
lozenges
rhombus
granules
Prior art date
Application number
BR9809651-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Andrew Day
Huw Lyn Jones
Carl Simon Smith
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of BR9809651A publication Critical patent/BR9809651A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9809651-6A 1997-05-22 1998-05-20 Processo para a fabricação de pastilhas de flurbiprofen de forma losangular BR9809651A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710521.7A GB9710521D0 (en) 1997-05-22 1997-05-22 Process
PCT/EP1998/003167 WO1998052539A1 (en) 1997-05-22 1998-05-20 Process for making flurbiprofen lozenges

Publications (1)

Publication Number Publication Date
BR9809651A true BR9809651A (pt) 2000-07-11

Family

ID=10812840

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809651-6A BR9809651A (pt) 1997-05-22 1998-05-20 Processo para a fabricação de pastilhas de flurbiprofen de forma losangular

Country Status (31)

Country Link
US (1) US6194003B1 (es)
EP (1) EP0983059B1 (es)
JP (1) JP2001527567A (es)
KR (1) KR20010012739A (es)
CN (1) CN1154480C (es)
AR (1) AR015812A1 (es)
AT (1) ATE245021T1 (es)
AU (1) AU725760B2 (es)
BG (1) BG103881A (es)
BR (1) BR9809651A (es)
CA (1) CA2290830C (es)
CZ (1) CZ290816B6 (es)
DE (1) DE69816440T2 (es)
DK (1) DK0983059T3 (es)
ES (1) ES2202871T3 (es)
GB (1) GB9710521D0 (es)
HU (1) HU224954B1 (es)
ID (1) ID22949A (es)
IL (1) IL132999A0 (es)
IN (1) IN187837B (es)
MY (1) MY118410A (es)
NO (1) NO995681D0 (es)
NZ (1) NZ500664A (es)
PL (1) PL190947B1 (es)
PT (1) PT983059E (es)
RU (1) RU2203046C2 (es)
SK (1) SK283701B6 (es)
TR (1) TR199902725T2 (es)
UA (1) UA53714C2 (es)
WO (1) WO1998052539A1 (es)
ZA (1) ZA984260B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124124B2 (en) 1999-12-09 2012-02-28 Reckitt Benckiser Healthcare (Uk) Limited Compressed tablet formulation comprising non-steroidal anti-inflammatory drugs and methods
AU2001257022B2 (en) * 2000-04-13 2005-02-03 Mayo Foundation For Medical Education And Research Abeta 42 lowering agents
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
JP2007528857A (ja) * 2003-07-11 2007-10-18 ミリアド ジェネティクス, インコーポレイテッド アルツハイマー病の処置のための薬学的方法、投与レジメンおよび投薬形態
FR2865648B1 (fr) 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
KR20070004036A (ko) * 2004-04-29 2007-01-05 키스톤 리테이닝 월 시스템스, 아이엔씨 벽, 옹벽 및 그 외 유사한 것을 위한 베니어
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
CN101128186B (zh) 2005-02-03 2013-07-03 奈科明制药有限公司 制备含钙组合物的快速湿聚结方法
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
EP1909777A2 (en) * 2005-07-22 2008-04-16 Myriad Genetics, Inc. High drug load formulations and dosage forms
AU2006312119B2 (en) * 2005-11-02 2010-04-29 Teikoku Pharma Usa, Inc. Organoleptically acceptable ibuprofen oral dosage formulations, methods of making and using the same
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
EA200901188A1 (ru) * 2007-07-23 2010-04-30 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Органолептически приемлемые дозированные лекарственные формы индольных агонистов серотониновых рецепторов для перорального применения и способы их применения
WO2010020772A2 (en) * 2008-08-22 2010-02-25 Reckitt Benckiser Healthcare (Uk) Limited Improvements in or relating to compositions
IT1397132B1 (it) 2009-12-01 2013-01-04 Alfa Wassermann Spa Composizioni comprendenti antiinfiammatori non steroidei.
IT1406107B1 (it) * 2010-12-13 2014-02-14 Alfa Wassermann Spa Composizioni solide comprendenti antiinfiammatori non steroidei, processi per la loro preparazione e loro uso.
PL3284459T3 (pl) 2011-04-29 2021-06-28 Moberg Pharma Ab Kompozycje farmaceutyczne zawierające środek miejscowo znieczulający, taki jak bupiwakaina, do podawania miejscowego do jamy ustnej lub gardła
EP2609911A1 (en) * 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. A novel process for preparing orally disintegrating flurbiprofen formulations
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
JP6315741B2 (ja) * 2015-08-18 2018-04-25 合同会社Pharma Seeds Create NSAIDsまたはヘパリン類含有口腔用組成物
WO2020013781A2 (en) * 2018-03-27 2020-01-16 Pisak Mehmet Nevzat Synergistic effect of flurbiprofen and a gastro protective agent for the treatment of pain and inflammation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4666716A (en) * 1984-09-04 1987-05-19 Richardson-Vicks Inc. Antidiarrheal compositions and use thereof
IT1243342B (it) 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
US5302394A (en) * 1992-07-14 1994-04-12 Mcneil-Ppc, Inc. Dextromethorphan continuous lozenge manufacturing process
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment

Also Published As

Publication number Publication date
RU2203046C2 (ru) 2003-04-27
PL336624A1 (en) 2000-07-03
WO1998052539A1 (en) 1998-11-26
JP2001527567A (ja) 2001-12-25
DK0983059T3 (da) 2003-11-03
TR199902725T2 (xx) 2000-02-21
BG103881A (en) 2000-05-31
IL132999A0 (en) 2001-03-19
CN1154480C (zh) 2004-06-23
ES2202871T3 (es) 2004-04-01
PL190947B1 (pl) 2006-02-28
NO995681L (no) 1999-11-19
EP0983059A1 (en) 2000-03-08
AR015812A1 (es) 2001-05-30
HUP0002121A2 (hu) 2000-12-28
KR20010012739A (ko) 2001-02-26
CN1255848A (zh) 2000-06-07
CZ412099A3 (cs) 2000-02-16
UA53714C2 (uk) 2003-02-17
CA2290830C (en) 2006-07-11
HU224954B1 (en) 2006-04-28
IN187837B (es) 2002-06-29
GB9710521D0 (en) 1997-07-16
HUP0002121A3 (en) 2001-04-28
ZA984260B (en) 1999-02-20
DE69816440D1 (de) 2003-08-21
EP0983059B1 (en) 2003-07-16
SK283701B6 (sk) 2003-12-02
SK158899A3 (en) 2000-05-16
NZ500664A (en) 2001-01-26
DE69816440T2 (de) 2004-05-13
NO995681D0 (no) 1999-11-19
ID22949A (id) 1999-12-16
AU7916598A (en) 1998-12-11
CA2290830A1 (en) 1998-11-26
PT983059E (pt) 2003-11-28
CZ290816B6 (cs) 2002-10-16
ATE245021T1 (de) 2003-08-15
MY118410A (en) 2004-10-30
AU725760B2 (en) 2000-10-19
US6194003B1 (en) 2001-02-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007.