PT84526B - Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno - Google Patents

Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno

Info

Publication number
PT84526B
PT84526B PT84526A PT8452687A PT84526B PT 84526 B PT84526 B PT 84526B PT 84526 A PT84526 A PT 84526A PT 8452687 A PT8452687 A PT 8452687A PT 84526 B PT84526 B PT 84526B
Authority
PT
Portugal
Prior art keywords
aggregate
crystals
consisting essentially
ibupphenic
preparation
Prior art date
Application number
PT84526A
Other languages
English (en)
Other versions
PT84526A (en
Inventor
Keith Allan
Richard Michael Slater
David Wesley Bogan
Jivn-Ren Chen
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of PT84526A publication Critical patent/PT84526A/pt
Publication of PT84526B publication Critical patent/PT84526B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT84526A 1986-03-19 1987-03-19 Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno PT84526B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868606762A GB8606762D0 (en) 1986-03-19 1986-03-19 Therapeutic agents

Publications (2)

Publication Number Publication Date
PT84526A PT84526A (en) 1987-04-01
PT84526B true PT84526B (pt) 1989-11-10

Family

ID=10594868

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84526A PT84526B (pt) 1986-03-19 1987-03-19 Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno

Country Status (21)

Country Link
EP (1) EP0241126B1 (pt)
JP (1) JPS62230723A (pt)
KR (1) KR870008582A (pt)
CN (1) CN87101974A (pt)
AT (1) ATE65393T1 (pt)
AU (1) AU7017787A (pt)
CS (1) CS182787A2 (pt)
DD (1) DD263232A5 (pt)
DE (1) DE3771544D1 (pt)
DK (1) DK136487A (pt)
FI (1) FI871112A (pt)
GB (2) GB8606762D0 (pt)
HU (1) HU195422B (pt)
IL (1) IL81884A0 (pt)
IN (1) IN163939B (pt)
NO (1) NO871120L (pt)
NZ (1) NZ219560A (pt)
PL (1) PL264695A1 (pt)
PT (1) PT84526B (pt)
YU (1) YU47087A (pt)
ZA (1) ZA871836B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833448A1 (de) * 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
CA2063141C (en) * 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
AU1193092A (en) * 1992-01-10 1993-08-03 Obschestvo S Ogranichennoi Otvetstvennostju Meditsinsky Nauchno-Proizvodstvenny Komplex Biotiki Granulated pharmaceutical composition and method of obtaining it
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
WO1995009615A1 (en) * 1993-10-01 1995-04-13 Astra Aktiebolag Process i
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
FR2804603B1 (fr) * 2000-02-04 2004-01-23 Rhodia Chimie Sa Procede continu pour formuler sous forme de granules une ou plusieurs matieres actives pharmaceutiques
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
ES2821528T3 (es) 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
JPS60120616A (ja) * 1983-12-05 1985-06-28 Yaskawa Electric Mfg Co Ltd プリセット型可逆カウンタ装置
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing

Also Published As

Publication number Publication date
DK136487D0 (da) 1987-03-17
KR870008582A (ko) 1987-10-19
NO871120D0 (no) 1987-03-18
DK136487A (da) 1987-09-20
NZ219560A (en) 1989-05-29
ZA871836B (en) 1987-09-02
ATE65393T1 (de) 1991-08-15
YU47087A (en) 1988-04-30
CS182787A2 (en) 1991-05-14
PL264695A1 (en) 1988-05-12
FI871112A (fi) 1987-09-20
GB2187952A (en) 1987-09-23
EP0241126B1 (en) 1991-07-24
HU195422B (en) 1988-05-30
AU7017787A (en) 1987-09-24
JPS62230723A (ja) 1987-10-09
GB2187952B (en) 1990-05-09
GB8704987D0 (en) 1987-04-08
HUT42939A (en) 1987-09-28
GB8606762D0 (en) 1986-04-23
IL81884A0 (en) 1987-10-20
EP0241126A1 (en) 1987-10-14
PT84526A (en) 1987-04-01
CN87101974A (zh) 1987-10-21
FI871112A0 (fi) 1987-03-13
DE3771544D1 (de) 1991-08-29
IN163939B (pt) 1988-12-10
DD263232A5 (de) 1988-12-28
NO871120L (no) 1987-09-21

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