ES2043210T3 - Forma solida de medicamento con elevado contenido de verapamil. - Google Patents

Forma solida de medicamento con elevado contenido de verapamil.

Info

Publication number
ES2043210T3
ES2043210T3 ES90118101T ES90118101T ES2043210T3 ES 2043210 T3 ES2043210 T3 ES 2043210T3 ES 90118101 T ES90118101 T ES 90118101T ES 90118101 T ES90118101 T ES 90118101T ES 2043210 T3 ES2043210 T3 ES 2043210T3
Authority
ES
Spain
Prior art keywords
verapamil
medication
solid form
high content
pelleting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90118101T
Other languages
English (en)
Inventor
Helmut Dr Fricke
Thomas Dr Moest
Ernst Dr Flaig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Application granted granted Critical
Publication of ES2043210T3 publication Critical patent/ES2043210T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

MEDICAMENTO SOLIDO CON UN CONTENIDO DE VERAPAMIL DEL 90 % EN PESO, COMO MINIMO. PROCEDIMIENTO PARA SU OBTENCION POR GRANULACION CON POCA AGUA A 30-50 (GRADOS) C, SECADO Y, EVENTUALMENTE, FORMACION DE TABLETAS O PELLETS DEL MODO HABITUAL, DE TAL MANERA QUE EL GRANULADO OBTENIDO TAL COMO SE DESCRIBE, VUELVE A HUMEDECERSE DE NUEVO DESPUES DE ENFRIADO, SIENDO COMPACTADO Y SECADO EN EL MEZCLADOR DE GRANULACION A 30 - 55 (GRADOS) C.
ES90118101T 1989-09-28 1990-09-20 Forma solida de medicamento con elevado contenido de verapamil. Expired - Lifetime ES2043210T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3932378A DE3932378A1 (de) 1989-09-28 1989-09-28 Feste arzneiform mit hohem verapamil-gehalt

Publications (1)

Publication Number Publication Date
ES2043210T3 true ES2043210T3 (es) 1993-12-16

Family

ID=6390380

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90118101T Expired - Lifetime ES2043210T3 (es) 1989-09-28 1990-09-20 Forma solida de medicamento con elevado contenido de verapamil.

Country Status (8)

Country Link
EP (1) EP0420042B1 (es)
JP (1) JP3100615B2 (es)
AT (1) ATE78159T1 (es)
CA (1) CA2026384C (es)
DE (2) DE3932378A1 (es)
DK (1) DK0420042T3 (es)
ES (1) ES2043210T3 (es)
GR (1) GR3005754T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1193092A (en) * 1992-01-10 1993-08-03 Obschestvo S Ogranichennoi Otvetstvennostju Meditsinsky Nauchno-Proizvodstvenny Komplex Biotiki Granulated pharmaceutical composition and method of obtaining it

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3113901A1 (de) * 1981-04-07 1982-10-28 Basf Ag, 6700 Ludwigshafen Wirkstoffzubereitung zur oralen applikation
LU86099A1 (fr) * 1985-09-30 1987-04-02 Pharlyse Formes galeniques a liberation prolongee du verapamil,leur fabrication et medicaments les contenant
JP2804048B2 (ja) * 1987-09-11 1998-09-24 イー・アール・スクイブ・アンド・サンズ・インコーポレイテッド 高薬物含量医薬組成物およびその製造法

Also Published As

Publication number Publication date
CA2026384A1 (en) 1991-03-29
DE3932378A1 (de) 1991-04-11
CA2026384C (en) 2002-04-09
DK0420042T3 (da) 1992-10-05
ATE78159T1 (de) 1992-08-15
GR3005754T3 (es) 1993-06-07
JP3100615B2 (ja) 2000-10-16
EP0420042A2 (de) 1991-04-03
DE59000209D1 (de) 1992-08-20
EP0420042A3 (en) 1991-04-24
JPH03167122A (ja) 1991-07-19
EP0420042B1 (de) 1992-07-15

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