BR9600370A - Benzenossulfoniluréias e-tiouréias substituídas processo para a sua preparação seus usos e medicamento contendo as mesmas - Google Patents

Benzenossulfoniluréias e-tiouréias substituídas processo para a sua preparação seus usos e medicamento contendo as mesmas

Info

Publication number
BR9600370A
BR9600370A BR9600370A BR9600370A BR9600370A BR 9600370 A BR9600370 A BR 9600370A BR 9600370 A BR9600370 A BR 9600370A BR 9600370 A BR9600370 A BR 9600370A BR 9600370 A BR9600370 A BR 9600370A
Authority
BR
Brazil
Prior art keywords
benzenesulfonylureas
preparation
same
medicine containing
thiourea substituted
Prior art date
Application number
BR9600370A
Other languages
English (en)
Inventor
Heinrich Englert
Joachim Kaiser
Uwe Gerlach
Peter Crause
Dieter Mania
Heinz Goegelein
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9600370A publication Critical patent/BR9600370A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42Sulfonylthioureas; Sulfonylisothioureas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
BR9600370A 1995-02-10 1996-02-09 Benzenossulfoniluréias e-tiouréias substituídas processo para a sua preparação seus usos e medicamento contendo as mesmas BR9600370A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19504379A DE19504379A1 (de) 1995-02-10 1995-02-10 Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
BR9600370A true BR9600370A (pt) 1998-03-03

Family

ID=7753608

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9600370A BR9600370A (pt) 1995-02-10 1996-02-09 Benzenossulfoniluréias e-tiouréias substituídas processo para a sua preparação seus usos e medicamento contendo as mesmas

Country Status (30)

Country Link
US (1) US5607976A (pt)
EP (1) EP0726250B1 (pt)
JP (1) JP3774773B2 (pt)
KR (1) KR100446565B1 (pt)
CN (1) CN1064041C (pt)
AR (1) AR001082A1 (pt)
AT (1) ATE197291T1 (pt)
AU (1) AU700883B2 (pt)
BR (1) BR9600370A (pt)
CA (1) CA2169219C (pt)
CZ (1) CZ290809B6 (pt)
DE (2) DE19504379A1 (pt)
DK (1) DK0726250T3 (pt)
ES (1) ES2152440T3 (pt)
FI (1) FI120394B (pt)
GR (1) GR3034886T3 (pt)
HR (1) HRP960063B1 (pt)
HU (1) HU224211B1 (pt)
IL (1) IL117078A (pt)
MY (1) MY114693A (pt)
NO (1) NO305750B1 (pt)
NZ (1) NZ280954A (pt)
PL (1) PL181656B1 (pt)
PT (1) PT726250E (pt)
RU (1) RU2155750C2 (pt)
SI (1) SI9600040B (pt)
SK (1) SK281357B6 (pt)
TR (1) TR199600747A2 (pt)
TW (1) TW419457B (pt)
ZA (1) ZA961050B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19832009A1 (de) 1998-07-16 2000-01-20 Hoechst Marion Roussel De Gmbh 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
DE19858253A1 (de) * 1998-12-17 2000-06-21 Aventis Pharma Gmbh Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden
DE10060809A1 (de) * 2000-12-07 2002-06-20 Aventis Pharma Gmbh Substituierte Anthranilsäuren, ihre Verwendung als Medikament oder Diagnostikum, sowie sie enthaltendes Medikament, sowie ein pharmazeutisches Kombinationspräparat mit einem Natrium/Wasserstoff-Austausch (NHE)-Blocker
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
CN1330630C (zh) * 2004-03-10 2007-08-08 中国药科大学 新的磺酰(硫)脲衍生物、其制备方法及含有它们的药物组合物
UA87854C2 (en) * 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
CN101466676B (zh) 2006-04-12 2012-07-18 默沙东公司 吡啶基酰胺类t-型钙通道拮抗剂
EP2212291B1 (en) * 2007-10-24 2014-06-04 Merck Sharp & Dohme Corp. Heterocycle phenyl amide t-type calcium channel antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE243821C (pt) *
DE1493672C3 (de) * 1964-08-01 1974-05-02 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Verfahren zur Herstellung von Benzolsulfonylharnstoffen
DE1518874C3 (de) * 1964-10-07 1975-03-13 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
DE1443919C3 (de) * 1964-12-28 1973-11-29 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe, Ver fahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitun gen
US3917690A (en) * 1966-11-29 1975-11-04 Hoechst Ag Benzenesulfonyl ureas and process for their manufacture
DE1568648C3 (de) * 1966-12-19 1975-03-27 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
BE754454A (fr) * 1969-08-06 1971-02-05 Bayer Ag Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
DE2413514C3 (de) * 1974-03-21 1982-03-04 Hoechst Ag, 6000 Frankfurt N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung
DE3011153A1 (de) * 1980-03-22 1981-10-15 Hoechst Ag, 6000 Frankfurt Verwendung von n-(4- spitze klammer auf 2-(5-chlor-2-methoxy-benzamido)-aethylspitze klammer zu -benzolsulfonyl)-n'-methyl-harnstoff
US5215985A (en) * 1990-07-20 1993-06-01 E. R. Squibb & Sons, Inc. Method for treating ischemic insult to neurons employing an ATP-sensitive potassium channel blocker
EP0612724B1 (de) * 1993-02-23 1996-12-27 Hoechst Aktiengesellschaft Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe- Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika

Also Published As

Publication number Publication date
IL117078A (en) 2001-01-11
US5607976A (en) 1997-03-04
IL117078A0 (en) 1996-06-18
HUT73975A (en) 1996-10-28
KR100446565B1 (ko) 2004-12-03
HRP960063A2 (en) 1997-10-31
AU4442996A (en) 1996-08-22
CN1137519A (zh) 1996-12-11
DE59606062D1 (de) 2000-12-07
PT726250E (pt) 2001-03-30
CZ290809B6 (cs) 2002-10-16
RU2155750C2 (ru) 2000-09-10
SI9600040A (en) 1996-10-31
TR199600747A2 (tr) 1996-08-21
TW419457B (en) 2001-01-21
HU224211B1 (hu) 2005-06-28
MY114693A (en) 2002-12-31
NZ280954A (en) 1996-10-28
ES2152440T3 (es) 2001-02-01
AR001082A1 (es) 1997-09-24
JP3774773B2 (ja) 2006-05-17
JPH08245553A (ja) 1996-09-24
CA2169219A1 (en) 1996-08-11
FI960587A0 (fi) 1996-02-08
DK0726250T3 (da) 2001-01-08
HRP960063B1 (en) 2001-08-31
FI120394B (fi) 2009-10-15
GR3034886T3 (en) 2001-02-28
ATE197291T1 (de) 2000-11-15
PL181656B1 (pl) 2001-08-31
EP0726250A1 (de) 1996-08-14
ZA961050B (en) 1996-08-29
NO960529D0 (no) 1996-02-09
NO305750B1 (no) 1999-07-19
NO960529L (no) 1996-08-12
EP0726250B1 (de) 2000-11-02
CN1064041C (zh) 2001-04-04
SK17596A3 (en) 1996-10-02
CZ38296A3 (en) 1996-08-14
FI960587A (fi) 1996-08-11
PL312531A1 (en) 1996-08-19
CA2169219C (en) 2009-01-06
SI9600040B (en) 2001-12-31
DE19504379A1 (de) 1996-08-14
KR960031431A (ko) 1996-09-17
HU9503932D0 (en) 1996-03-28
AU700883B2 (en) 1999-01-14
SK281357B6 (sk) 2001-02-12

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Legal Events

Date Code Title Description
FB34 Technical and formal requirements: requirement - article 34 of industrial property law
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE PATENTE COM BASE NOS ARTIGOS 8 E 13 DA LPI NO 9.279 DE 14/05/1996.