BR112021026604A2 - Processo para a produção de uma modificação cristalina metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iv) - Google Patents

Processo para a produção de uma modificação cristalina metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iv)

Info

Publication number
BR112021026604A2
BR112021026604A2 BR112021026604A BR112021026604A BR112021026604A2 BR 112021026604 A2 BR112021026604 A2 BR 112021026604A2 BR 112021026604 A BR112021026604 A BR 112021026604A BR 112021026604 A BR112021026604 A BR 112021026604A BR 112021026604 A2 BR112021026604 A2 BR 112021026604A2
Authority
BR
Brazil
Prior art keywords
aminoiminomethyl
producing
crystalline modification
aminoethanoic acid
metastable crystalline
Prior art date
Application number
BR112021026604A
Other languages
English (en)
Inventor
Franz Thalhammer
Jürgen Sans
Thomas Güthner
Original Assignee
Alzchem Trostberg Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102019118893.8A external-priority patent/DE102019118893A1/de
Priority claimed from DE102019118894.6A external-priority patent/DE102019118894A1/de
Application filed by Alzchem Trostberg Gmbh filed Critical Alzchem Trostberg Gmbh
Publication of BR112021026604A2 publication Critical patent/BR112021026604A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Fodder In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

processo para a produção de uma modificação cristalina metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iv). a presente invenção refere-se a um processo para a produção de ácido n-(aminoiminometil)-2-aminoetanóico contendo ácido n-(aminoiminometil)-2-aminoetanóico em uma modificação cristalina termodinamicamente metaestável.
BR112021026604A 2019-07-12 2020-06-25 Processo para a produção de uma modificação cristalina metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iv) BR112021026604A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102019118893.8A DE102019118893A1 (de) 2019-07-12 2019-07-12 Metastabile Kristallmodifikation und Verfahren zu deren Herstellung (I)
DE102019118894.6A DE102019118894A1 (de) 2019-07-12 2019-07-12 Metastabile Kristallmodifikation und Verfahren zu deren Herstellung (II)
PCT/EP2020/067842 WO2021008846A1 (de) 2019-07-12 2020-06-25 Verfahren zur herstellung einer metastabilen kristallmodifikation von n-(aminoiminomethyl)-2-aminoethansäure (iv)

Publications (1)

Publication Number Publication Date
BR112021026604A2 true BR112021026604A2 (pt) 2022-05-10

Family

ID=71409379

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112021026604A BR112021026604A2 (pt) 2019-07-12 2020-06-25 Processo para a produção de uma modificação cristalina metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iv)
BR112021022116A BR112021022116A2 (pt) 2019-07-12 2020-06-25 Método para a produção de uma modificação de cristal metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iii)

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112021022116A BR112021022116A2 (pt) 2019-07-12 2020-06-25 Método para a produção de uma modificação de cristal metaestável de ácido n-(aminoiminometil)-2-aminoetanóico (iii)

Country Status (14)

Country Link
US (3) US20220388948A1 (pt)
EP (5) EP3997063B1 (pt)
JP (2) JP2022540331A (pt)
KR (2) KR102648292B1 (pt)
CN (5) CN114072378B (pt)
BR (2) BR112021026604A2 (pt)
CO (2) CO2021016703A2 (pt)
ES (2) ES2954944T3 (pt)
HU (2) HUE063674T2 (pt)
IL (3) IL287827B1 (pt)
MX (2) MX2022000499A (pt)
PL (2) PL3997064T3 (pt)
WO (4) WO2021008843A1 (pt)
ZA (4) ZA202108515B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022540331A (ja) * 2019-07-12 2022-09-15 アルツヒエム トローストベアク ゲー・エム・べー・ハー Ｎ－（アミノイミノメチル）－２－アミノ酢酸（ｉｉｉ）の準安定結晶変態の製造方法

Family Cites Families (22)

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US2654779A (en) * 1950-12-23 1953-10-06 Int Minerals & Chem Corp Method of preparation of guanidino fatty acids
DE964590C (de) * 1950-12-23 1957-05-23 Int Minerals & Chem Corp Verfahren zur Herstellung von Glykocyamin
US2620354A (en) 1951-01-12 1952-12-02 Int Minerals & Chem Corp Production of guanidino fatty acids
CH587268A5 (en) 1972-06-29 1977-04-29 Ciba Geigy Ag Substd carboxylic acid derivs - broad spectrum antibiotics and inters
JPS6054320A (ja) 1983-08-31 1985-03-28 Morishita Seiyaku Kk 腎疾患治療剤
SE502756C2 (sv) * 1990-02-06 1996-01-08 Rexolin Chem Ab Förfarande för rening av mandelsyra-N,N-dietylamid
US6083549A (en) * 1995-07-19 2000-07-04 Ajinomoto Co., Inc. Taste-improving agent and a food having improved taste
WO2000059528A1 (en) 1999-04-02 2000-10-12 The Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
PT1758463E (pt) 2004-06-09 2008-04-03 Alzchem Trostberg Gmbh Ácido guanidinoacético como aditivo para rações para animais
DE102006016227A1 (de) * 2006-04-06 2007-10-11 Degussa Gmbh Verfahren zur Herstellung von Kreatin, Kreatin-Monohydrat oder Guanidinoessigsäure
DE102007004781A1 (de) 2007-01-31 2008-08-07 Alzchem Trostberg Gmbh Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels
DE102007034102A1 (de) * 2007-07-21 2009-01-22 Alzchem Trostberg Gmbh Abriebfeste und rieselfähige Glycocyamin-haltige Formlinge und Verfahren zu deren Herstellung
DE102007053369A1 (de) 2007-11-09 2009-07-02 Alzchem Trostberg Gmbh Verwendung einer eine Kreatin-Komponente enthaltende Zusammensetzung zur Verbesserung der männlichen Fruchtbarkeit
CN101525305B (zh) * 2009-04-17 2012-01-04 北京君德同创农牧科技股份有限公司 胍基乙酸及其盐的合成方法
CN102329250A (zh) * 2011-07-22 2012-01-25 周彬 胍基乙酸的化学合成方法
CN102702032A (zh) * 2012-05-10 2012-10-03 江苏远洋药业股份有限公司 胍基乙酸的合成方法
CN105777594A (zh) * 2014-12-26 2016-07-20 王建华 一种硫醇化合物的清洁生产方法
CN106361736B (zh) 2015-07-24 2020-02-07 上海医药工业研究院 一种胍基化合物的应用
CN105503659A (zh) * 2016-01-29 2016-04-20 浙江汇能生物股份有限公司 一种高纯度高收率胍基乙酸的合成方法
GB201603571D0 (en) * 2016-03-01 2016-04-13 Univ Warwick Markers for skeletal disorders
JP2018063208A (ja) * 2016-10-14 2018-04-19 Ｂｌｏｏｍ Ｔｅｃｈｎｏｌｏｇｙ 株式会社 終末糖化産物の濃縮方法
JP2022540331A (ja) * 2019-07-12 2022-09-15 アルツヒエム トローストベアク ゲー・エム・べー・ハー Ｎ－（アミノイミノメチル）－２－アミノ酢酸（ｉｉｉ）の準安定結晶変態の製造方法

Also Published As

Publication number Publication date
IL287827A (en) 2022-01-01
EP3997064B1 (de) 2023-08-09
ES2954944T3 (es) 2023-11-27
IL275660B2 (en) 2023-06-01
EP3997062A1 (de) 2022-05-18
JP2022540331A (ja) 2022-09-15
HUE063674T2 (hu) 2024-01-28
CO2022000495A2 (es) 2022-01-28
EP4296262A1 (de) 2023-12-27
CN113710648A (zh) 2021-11-26
CN113784947A (zh) 2021-12-10
CN114072378B (zh) 2024-02-02
ZA202108515B (en) 2023-01-25
IL275659B (en) 2022-11-01
EP3997063B1 (de) 2023-08-02
IL275659A (en) 2021-01-31
EP3997064A1 (de) 2022-05-18
EP3997064C0 (de) 2023-08-09
MX2022000499A (es) 2022-02-03
CN115594615A (zh) 2023-01-13
JP7403624B2 (ja) 2023-12-22
CN113784947B (zh) 2023-09-29
ZA202211321B (en) 2023-11-29
WO2021008846A1 (de) 2021-01-21
CN114096519B (zh) 2023-09-15
KR20220034035A (ko) 2022-03-17
PL3997063T3 (pl) 2023-10-23
EP3997065B1 (de) 2023-08-02
ES2955483T3 (es) 2023-12-01
CO2021016703A2 (es) 2022-03-18
WO2021008845A1 (de) 2021-01-21
CN114072378A (zh) 2022-02-18
JP2022540451A (ja) 2022-09-15
IL275660B1 (pt) 2023-02-01
ZA202200283B (en) 2023-04-26
US20220204443A1 (en) 2022-06-30
US11512047B2 (en) 2022-11-29
US20220388948A1 (en) 2022-12-08
WO2021008844A1 (de) 2021-01-21
EP3997063C0 (de) 2023-08-02
KR102648292B1 (ko) 2024-03-15
EP3997063A1 (de) 2022-05-18
KR20220032526A (ko) 2022-03-15
HUE063187T2 (hu) 2024-01-28
US20220289670A1 (en) 2022-09-15
WO2021008843A1 (de) 2021-01-21
EP3997065A1 (de) 2022-05-18
EP3997065C0 (de) 2023-08-02
CN114096519A (zh) 2022-02-25
BR112021024244A2 (pt) 2022-04-12
CN113710648B (zh) 2023-09-12
IL275659B2 (en) 2023-03-01
MX2022000519A (es) 2022-07-13
BR112021022116A2 (pt) 2022-02-08
PL3997064T3 (pl) 2023-11-20
CN115594615B (zh) 2023-11-07
IL287827B1 (en) 2024-05-01
IL275660A (en) 2021-01-31
ZA202109576B (en) 2022-11-30

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Legal Events

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B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

Free format text: O PEDIDO FOI DIVIDIDO NO BR122023003371-0 PROTOCOLO 870230015529 EM 23/02/2023 17:56.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/06/2020, OBSERVADAS AS CONDICOES LEGAIS