BR112023005850A2 - Processo para purificação de pleuromutilinas - Google Patents

Processo para purificação de pleuromutilinas

Info

Publication number
BR112023005850A2
BR112023005850A2 BR112023005850A BR112023005850A BR112023005850A2 BR 112023005850 A2 BR112023005850 A2 BR 112023005850A2 BR 112023005850 A BR112023005850 A BR 112023005850A BR 112023005850 A BR112023005850 A BR 112023005850A BR 112023005850 A2 BR112023005850 A2 BR 112023005850A2
Authority
BR
Brazil
Prior art keywords
pleuromutilins
purification
processes
producing
relates
Prior art date
Application number
BR112023005850A
Other languages
English (en)
Inventor
Pierce Larry
Original Assignee
Elanco Tiergesundheit Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elanco Tiergesundheit Ag filed Critical Elanco Tiergesundheit Ag
Publication of BR112023005850A2 publication Critical patent/BR112023005850A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/08Purification; Separation; Stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/60Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26Separation; Purification; Stabilisation; Use of additives
    • C07C319/28Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C07D303/17Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals containing oxirane rings condensed with carbocyclic ring systems having three or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/76Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members
    • C07C2603/84Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing rings with more than eight members

Abstract

PROCESSO PARA PURIFICAÇÃO DE PLEUROMUTILINAS. A presente invenção refere-se a processos para produção de pleuromutilinas.
BR112023005850A 2020-10-29 2021-10-29 Processo para purificação de pleuromutilinas BR112023005850A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063106920P 2020-10-29 2020-10-29
PCT/US2021/057304 WO2022094247A1 (en) 2020-10-29 2021-10-29 Process for purification of pleuromutilins

Publications (1)

Publication Number Publication Date
BR112023005850A2 true BR112023005850A2 (pt) 2023-05-09

Family

ID=81383263

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023005850A BR112023005850A2 (pt) 2020-10-29 2021-10-29 Processo para purificação de pleuromutilinas

Country Status (13)

Country Link
US (1) US20230265040A1 (pt)
EP (1) EP4237403A1 (pt)
JP (1) JP2023548968A (pt)
KR (1) KR20230098233A (pt)
CN (1) CN117480151A (pt)
AR (1) AR123965A1 (pt)
AU (1) AU2021369809A1 (pt)
BR (1) BR112023005850A2 (pt)
CA (1) CA3195311A1 (pt)
CL (1) CL2023001137A1 (pt)
MX (1) MX2023004950A (pt)
TW (1) TW202233562A (pt)
WO (1) WO2022094247A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116199690B (zh) * 2023-04-28 2023-07-07 西华大学 嘌呤类截短侧耳素衍生物、立体异构体或药学上可接受的盐及其用途和药物组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103450061B (zh) * 2012-05-29 2014-10-22 大英九合生物化工股份有限公司 一种工业生产中泰妙菌素反应液的纯化方法
EP3423159A4 (en) * 2016-03-02 2019-11-06 Anacor Pharmaceuticals, Inc. BORN SMALL MOLECULES
WO2018144717A1 (en) * 2017-02-01 2018-08-09 Yale University New pleuromutilin antibiotic compounds, compositions and methods of use and synthesis
TWI762573B (zh) * 2017-02-10 2022-05-01 奧地利商納畢瓦治療有限責任公司 截短側耳素之純化

Also Published As

Publication number Publication date
WO2022094247A1 (en) 2022-05-05
KR20230098233A (ko) 2023-07-03
AR123965A1 (es) 2023-01-25
MX2023004950A (es) 2023-05-17
TW202233562A (zh) 2022-09-01
AU2021369809A1 (en) 2023-05-11
JP2023548968A (ja) 2023-11-21
US20230265040A1 (en) 2023-08-24
EP4237403A1 (en) 2023-09-06
CN117480151A (zh) 2024-01-30
CL2023001137A1 (es) 2023-11-24
CA3195311A1 (en) 2022-05-05

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