BR112023002636A2 - Microrganismo para produzir putrescina e processo para produzir putrescina usando o mesmo - Google Patents

Microrganismo para produzir putrescina e processo para produzir putrescina usando o mesmo

Info

Publication number
BR112023002636A2
BR112023002636A2 BR112023002636A BR112023002636A BR112023002636A2 BR 112023002636 A2 BR112023002636 A2 BR 112023002636A2 BR 112023002636 A BR112023002636 A BR 112023002636A BR 112023002636 A BR112023002636 A BR 112023002636A BR 112023002636 A2 BR112023002636 A2 BR 112023002636A2
Authority
BR
Brazil
Prior art keywords
putrescin
produce
microorganism
same
producing
Prior art date
Application number
BR112023002636A
Other languages
English (en)
Inventor
Lee Jaehun
Min Lee Kyoung
Bae Hyun-Jung
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112023002636A2 publication Critical patent/BR112023002636A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01001—Amino-acid N-acetyltransferase (2.3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01005—Arylamine N-acetyltransferase (2.3.1.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01035—Glutamate N-acetyltransferase (2.3.1.35)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01016—Acetylornithine deacetylase (3.5.1.16)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/101—Plasmid DNA for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

MICRORGANISMO PARA PRODUZIR PUTRESCINA E PROCESSO PARA PRODUZIR PUTRESCINA USANDO O MESMO. A presente invenção se refere a um microrganismo para produzir putrescina e a um método para produzir putrescina usando o mesmo.
BR112023002636A 2020-08-13 2021-03-19 Microrganismo para produzir putrescina e processo para produzir putrescina usando o mesmo BR112023002636A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020200101894A KR102246288B1 (ko) 2020-08-13 2020-08-13 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법
PCT/KR2021/003408 WO2022035011A1 (ko) 2020-08-13 2021-03-19 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법

Publications (1)

Publication Number Publication Date
BR112023002636A2 true BR112023002636A2 (pt) 2023-04-04

Family

ID=75728438

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023002636A BR112023002636A2 (pt) 2020-08-13 2021-03-19 Microrganismo para produzir putrescina e processo para produzir putrescina usando o mesmo

Country Status (10)

Country Link
US (1) US20230392174A1 (pt)
EP (1) EP4198131A4 (pt)
JP (1) JP2023538009A (pt)
KR (1) KR102246288B1 (pt)
CN (1) CN116648504A (pt)
AU (1) AU2021325749A1 (pt)
BR (1) BR112023002636A2 (pt)
CA (1) CA3189239A1 (pt)
MX (1) MX2023001849A (pt)
WO (1) WO2022035011A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108893438B (zh) * 2018-06-25 2022-09-06 江南大学 一种提高钝齿棒杆菌合成l-鸟氨酸产量的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2236613T3 (pl) 2004-07-15 2015-11-30 Dsm Ip Assets Bv Biochemiczna synteza 1,4-butanodiaminy
NZ552631A (en) 2004-07-15 2009-09-25 Dsm Ip Assets Bv Biochemical synthesis of 1,4-butanediamine
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
KR100930203B1 (ko) 2008-01-28 2009-12-07 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
MY175283A (en) * 2008-04-10 2020-06-18 Korea Advanced Inst Sci & Tech Mutant microorganisms having high ability to produce putrescine and method for producing putrescine using the same
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
KR101188432B1 (ko) * 2008-04-10 2012-10-08 한국과학기술원 퓨트레신 고생성능을 가지는 변이 미생물 및 이를 이용한 퓨트레신의 제조방법
KR101348461B1 (ko) 2010-12-08 2014-01-08 씨제이제일제당 (주) 퓨트레신을 생산하는 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법
ES2655764T3 (es) 2012-01-11 2018-02-21 Cj Cheiljedang Corporation Microorganismo recombinante que tiene una capacidad mejorada de producción de putrescina y un procedimiento para producir putrescina utilizando el mismo
JP6526792B2 (ja) * 2014-04-25 2019-06-05 シージェイ チェイルジェダン コーポレーション プトレシンを生産する微生物及びそれらを用いてプトレシンを生産する方法
KR101632642B1 (ko) 2015-01-29 2016-06-22 씨제이제일제당 주식회사 신규한 프로모터 및 그의 용도
KR101735935B1 (ko) * 2015-07-20 2017-05-16 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법
WO2017097828A1 (en) * 2015-12-07 2017-06-15 Danmarks Tekniske Universitet Bacterial cells with improved tolerance to polyamines
CN108559746B (zh) 2016-08-31 2021-09-03 Cj第一制糖株式会社 新型启动子及其应用

Also Published As

Publication number Publication date
KR102246288B1 (ko) 2021-04-29
EP4198131A4 (en) 2024-02-21
CN116648504A (zh) 2023-08-25
MX2023001849A (es) 2023-05-08
JP2023538009A (ja) 2023-09-06
WO2022035011A1 (ko) 2022-02-17
EP4198131A1 (en) 2023-06-21
AU2021325749A9 (en) 2023-04-27
US20230392174A1 (en) 2023-12-07
AU2021325749A1 (en) 2023-04-20
CA3189239A1 (en) 2022-02-17

Similar Documents

Publication Publication Date Title
BR112023000183A2 (pt) Microrganismo e métodos para produção fermentativa de ácido guanidinoacético e creatina
BR112022002604A2 (pt) Processo de produção de moduladores de cftr
AR120771A1 (es) Procedimiento de producción fermentativa de ácido guanidinoacético
AR115301A1 (es) Microorganismo que tiene aumento de productividad de glicina y método para producir una composición fermentada usando el mismo
AR122914A1 (es) Método para la producción fermentativa de ácido guanidinoacético
MX2019007397A (es) Nueva acido 5'-inosinico deshidrogenasa y procedimiento de preparacion de acido 5'-inosinico usando la misma.
BR112014014656A2 (pt) processo inovador de cultivo de bactéria para aprimoramento de produtividade de polioses capsulares
BR112023024041A2 (pt) Micro-organismo, e método para a produção fermentativa de ácido guanidinoacético (gaa) e creatina
MX2020008809A (es) Un microorganismo que produce un aminoácido similar a la micosporina y un procedimiento de producción de un aminoácido similar a la micosporina mediante el uso del mismo.
BR112023002636A2 (pt) Microrganismo para produzir putrescina e processo para produzir putrescina usando o mesmo
BR112018003756A2 (pt) microorganismo corynebacterium sp. capaz de produzir l-lisina e método para produzir l-lisina usando o mesmo
CL2021001511A1 (es) Novedosa psicosa-6-fosfato fosfatasa, composición para la producción de psicosa que comprende la misma y procedimiento para la producción de psicosa mediante el uso de la misma
BR112023004335A2 (pt) Microrganismo recombinante para produzir ácido l-glutâmico e um método para produzir ácido l-glutâmico usando o mesmo
BR112021018712A2 (pt) Micro-organismo do gênero corynebacterium para produzir l-treonina, composição para produzir l-treonina, método para produzir l-treonina, e, uso de um micro-organismo do gênero
BR112018004873A8 (pt) Método de cultura de haematococcus espécies para a fabricação de astaxantina
BR112023000227A2 (pt) Processo para preparação de dismina
BR112023017216A2 (pt) Variante de citrato sintase inovadora e método para produzir l-valina com o uso da mesma
WO2019017706A3 (ko) 퓨트레신을 생산하는 미생물 및 이를 이용한 퓨트레신 생산방법
BR112021017167A2 (pt) Processo para a produção de um caldo de fermentação
AR120516A1 (es) Microorganismo y método para producir ergotioneína
BR112023005850A2 (pt) Processo para purificação de pleuromutilinas
BR112022008296A2 (pt) Processo para produzir e regenerar compostos transportadores de hidrogênio
BR112023023931A2 (pt) Processo e aparelho para a produção de hidrogênio, e hidrogênio
MX2019009383A (es) Microorganismo del genero corynebacterium productor de l-arginina y metodo para producir l-arginina usando el mismo.
BR112021014194A2 (pt) Método para a produção de um l-aminoácido