MX2019007397A - Nueva acido 5'-inosinico deshidrogenasa y procedimiento de preparacion de acido 5'-inosinico usando la misma. - Google Patents

Nueva acido 5'-inosinico deshidrogenasa y procedimiento de preparacion de acido 5'-inosinico usando la misma.

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Publication number
MX2019007397A
MX2019007397A MX2019007397A MX2019007397A MX2019007397A MX 2019007397 A MX2019007397 A MX 2019007397A MX 2019007397 A MX2019007397 A MX 2019007397A MX 2019007397 A MX2019007397 A MX 2019007397A MX 2019007397 A MX2019007397 A MX 2019007397A
Authority
MX
Mexico
Prior art keywords
inosine monophosphate
same
novel
production method
dehydrogenase
Prior art date
Application number
MX2019007397A
Other languages
English (en)
Inventor
Ji Hye Lee
Min Ji Baek
So-Jung Park
Jin Sook Chang
Byoung Hoo Yoon
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2019007397A publication Critical patent/MX2019007397A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01205—IMP dehydrogenase (1.1.1.205)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se proporciona una variante de ácido 5'-inosínico deshidrogenasa, un microorganismo que incluye la misma y un procedimiento para preparar ácido 5'-inosínico utilizando la misma.
MX2019007397A 2018-07-27 2018-08-16 Nueva acido 5'-inosinico deshidrogenasa y procedimiento de preparacion de acido 5'-inosinico usando la misma. MX2019007397A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180087597A KR101956510B1 (ko) 2018-07-27 2018-07-27 신규 5'-이노신산 디하이드로게나아제 및 이를 이용한 5'-이노신산 제조방법
PCT/KR2018/009378 WO2020022547A1 (ko) 2018-07-27 2018-08-16 신규 5'-이노신산 디하이드로게나아제 및 이를 이용한 5'-이노신산 제조방법

Publications (1)

Publication Number Publication Date
MX2019007397A true MX2019007397A (es) 2020-10-01

Family

ID=65801409

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019007397A MX2019007397A (es) 2018-07-27 2018-08-16 Nueva acido 5'-inosinico deshidrogenasa y procedimiento de preparacion de acido 5'-inosinico usando la misma.

Country Status (15)

Country Link
US (1) US11066687B2 (es)
EP (1) EP3705572A4 (es)
JP (1) JP6873244B2 (es)
KR (1) KR101956510B1 (es)
CN (1) CN111183218B (es)
AU (1) AU2018386358B2 (es)
BR (1) BR112019020962B1 (es)
CA (1) CA3051217C (es)
MX (1) MX2019007397A (es)
MY (1) MY193486A (es)
RU (1) RU2728334C1 (es)
SG (1) SG11201909227XA (es)
TW (1) TWI710634B (es)
WO (1) WO2020022547A1 (es)
ZA (1) ZA201906063B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102185850B1 (ko) * 2020-02-21 2020-12-02 씨제이제일제당 주식회사 퓨린 뉴클레오티드를 생산하는 미생물 및 이를 이용한 퓨린 뉴클레오티드의 생산방법
KR102254628B1 (ko) * 2021-01-15 2021-05-21 씨제이제일제당 주식회사 신규한 포름이미도일글루타마아제 변이체 및 이를 이용한 imp 생산 방법
KR102254630B1 (ko) * 2021-01-15 2021-05-21 씨제이제일제당 주식회사 신규한 셀레니드, 물 디키나제 변이체 및 이를 이용한 imp 생산 방법
KR102270701B1 (ko) * 2021-01-15 2021-06-29 씨제이제일제당 주식회사 신규한 d-알라닌―d-알라닌 리가아제 변이체 및 이를 이용한 imp 생산 방법
KR102254632B1 (ko) * 2021-01-15 2021-05-21 씨제이제일제당 주식회사 신규한 피토엔 탈포화효소 변이체 및 이를 이용한 imp 생산 방법
KR102254631B1 (ko) * 2021-01-15 2021-05-21 씨제이제일제당 주식회사 신규한 펩타이드 메티오닌 설폭사이드 환원효소 변이체 및 이를 이용한 imp 생산 방법
KR102288396B1 (ko) * 2021-01-18 2021-08-10 씨제이제일제당 주식회사 신규한 혐기성 코프로포르피리노겐 ⅲ 옥시다제 변이체 및 이를 이용한 imp 생산 방법
KR102273639B1 (ko) * 2021-04-20 2021-07-06 씨제이제일제당 주식회사 신규한 이중기능성 메틸렌테트라히드로폴레이트 탈수소효소/메테닐테트라하이드로폴레이트 사이클로하이드롤라아제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
WO2022231037A1 (ko) * 2021-04-29 2022-11-03 씨제이제일제당 (주) 신규한 변이체 및 이를 이용한 imp 생산 방법
KR102634303B1 (ko) 2021-05-21 2024-02-06 씨제이제일제당 주식회사 퓨린 뉴클레오티드를 생산하는 미생물 및 이를 이용한 퓨린 뉴클레오티드의 생산방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55150899A (en) * 1979-05-14 1980-11-25 Ajinomoto Co Inc Production of 5'-inosinic acid through fermentation process
JP2545078B2 (ja) * 1987-04-06 1996-10-16 協和醗酵工業株式会社 核酸関連物質の製造法
JP2886550B2 (ja) * 1989-05-26 1999-04-26 協和醗酵工業株式会社 発酵法による５’―イノシン酸の製造法
US5358855A (en) * 1992-05-14 1994-10-25 The Medical College Of Pennsylvania Inosinic acid dehydrogenase assay
HU221120B1 (en) * 1993-10-28 2002-08-28 Ajinomoto Kk Process for producing different substances with use of microorganism
KR100397321B1 (ko) * 2000-12-26 2003-09-06 씨제이 주식회사 5'-이노신산을 고수율로 생산하는 미생물 코리네박테리움암모니아게네스 씨제이아이피009 및 그를 이용한5'-이노신산 생산방법
KR20020074811A (ko) * 2001-03-22 2002-10-04 제일제당주식회사 5'-이노신산을 생산하는 미생물
KR20070060206A (ko) * 2005-12-08 2007-06-13 씨제이 주식회사 증가된 글리세르알데히드-3-포스페이트 디히드로게나제유전자의 발현량을 갖는 5'-이노신산 생산성이 우수한코리네박테리움 속 미생물 및 그를 이용하여 5'-이노신산을생산하는 방법
WO2009107631A1 (ja) * 2008-02-25 2009-09-03 味の素株式会社 ５’－グアニル酸の製造法
KR101166027B1 (ko) * 2009-04-01 2012-07-19 씨제이제일제당 (주) 5'-이노신산 생산성이 향상된 코리네박테리움 속 미생물 및 이를 이용한 핵산의 생산방법
KR101500848B1 (ko) * 2013-07-23 2015-03-09 씨제이제일제당 (주) 천연 뉴트럴 조미소재의 제조 방법
KR102561863B1 (ko) * 2014-11-19 2023-08-01 바스프 에스이 Imp 데히드로게나아제 활성을 증가시키기 위한 에레모테시움의 유전적 변형
KR101744958B1 (ko) * 2014-12-24 2017-06-12 대상 주식회사 5’-이노신산의 고생성능 코리네박테리움 암모니아게네스 변이 균주 및 이를 이용한 5’-이노신산의 제조 방법
KR101916611B1 (ko) * 2017-12-15 2018-11-07 씨제이제일제당 (주) 신규 폴리펩타이드 및 이를 이용한 imp 생산방법

Also Published As

Publication number Publication date
US20210139939A1 (en) 2021-05-13
EP3705572A1 (en) 2020-09-09
AU2018386358A1 (en) 2020-02-13
BR112019020962B1 (pt) 2022-06-14
JP6873244B2 (ja) 2021-05-19
CA3051217C (en) 2021-01-26
CN111183218B (zh) 2021-04-06
MY193486A (en) 2022-10-17
RU2728334C1 (ru) 2020-07-29
CA3051217A1 (en) 2020-01-27
JP2020533947A (ja) 2020-11-26
ZA201906063B (en) 2021-05-26
EP3705572A4 (en) 2021-12-01
AU2018386358B2 (en) 2020-07-23
CN111183218A (zh) 2020-05-19
KR101956510B1 (ko) 2019-03-08
TW202012626A (zh) 2020-04-01
BR112019020962A2 (pt) 2020-05-05
US11066687B2 (en) 2021-07-20
WO2020022547A1 (ko) 2020-01-30
SG11201909227XA (en) 2020-02-27
TWI710634B (zh) 2020-11-21

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