MX2019011479A - Variante de fosforribosil pirofosfato amidotransferasa y procedimiento de preparacion de nucleotido de purina utilizando la misma. - Google Patents

Variante de fosforribosil pirofosfato amidotransferasa y procedimiento de preparacion de nucleotido de purina utilizando la misma.

Info

Publication number
MX2019011479A
MX2019011479A MX2019011479A MX2019011479A MX2019011479A MX 2019011479 A MX2019011479 A MX 2019011479A MX 2019011479 A MX2019011479 A MX 2019011479A MX 2019011479 A MX2019011479 A MX 2019011479A MX 2019011479 A MX2019011479 A MX 2019011479A
Authority
MX
Mexico
Prior art keywords
variant
same
purine nucleotide
phosphoribosyl pyrophosphate
pyrophosphate amidotransferase
Prior art date
Application number
MX2019011479A
Other languages
English (en)
Inventor
Ji Hye Lee
Min Ji Baek
So-Jung Park
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of MX2019011479A publication Critical patent/MX2019011479A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02014—Amidophosphoribosyltransferase (2.4.2.14)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Se proporciona una variante de fosforribosil pirofosfato amidotransferasa, un microorganismo que la incluye y un procedimiento de preparación de un nucleótido de purina utilizando la misma.
MX2019011479A 2019-03-28 2019-07-19 Variante de fosforribosil pirofosfato amidotransferasa y procedimiento de preparacion de nucleotido de purina utilizando la misma. MX2019011479A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190035683A KR102006977B1 (ko) 2019-03-28 2019-03-28 변이형 포스포리보실피로포스페이트 아미도트랜스퍼라아제 및 이를 이용한 퓨린 뉴클레오티드 제조방법
PCT/KR2019/008924 WO2020196993A1 (ko) 2019-03-28 2019-07-19 변이형 포스포리보실피로포스페이트 아미도트랜스퍼라아제 및 이를 이용한 퓨린 뉴클레오티드 제조방법

Publications (1)

Publication Number Publication Date
MX2019011479A true MX2019011479A (es) 2020-11-13

Family

ID=67616121

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019011479A MX2019011479A (es) 2019-03-28 2019-07-19 Variante de fosforribosil pirofosfato amidotransferasa y procedimiento de preparacion de nucleotido de purina utilizando la misma.

Country Status (18)

Country Link
US (1) US11008599B2 (es)
EP (1) EP3739044B1 (es)
JP (1) JP6891292B2 (es)
KR (1) KR102006977B1 (es)
CN (1) CN112004926B (es)
AU (1) AU2019226146B2 (es)
BR (1) BR112019020178B1 (es)
ES (1) ES2955417T3 (es)
HU (1) HUE063033T2 (es)
MX (1) MX2019011479A (es)
MY (1) MY192935A (es)
PL (1) PL3739044T3 (es)
PT (1) PT3739044T (es)
RU (1) RU2736372C1 (es)
SG (1) SG11201907885WA (es)
TW (1) TWI738050B (es)
WO (1) WO2020196993A1 (es)
ZA (1) ZA201905668B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100771511B1 (ko) * 2006-03-09 2007-10-30 삼성코닝 주식회사 분할 구동용 백 라이트 유닛 및 그 백 라이트 유닛의비대칭 발광 다이오드 렌즈
KR102013873B1 (ko) 2018-01-25 2019-08-23 씨제이제일제당 주식회사 퓨린 뉴클레오티드를 생산하는 코리네박테리움 속 미생물 및 이를 이용한 퓨린 뉴클레오티드의 생산방법
CN113106080B (zh) * 2021-03-31 2022-02-25 深圳希吉亚生物技术有限公司 烟酰胺磷酸核糖转移酶突变体及其应用
KR102277410B1 (ko) * 2021-04-29 2021-07-14 씨제이제일제당 주식회사 신규한 이중기능성 pyr 오페론 전사조절자/우라실 포스포리보실 전달 효소 변이체 및 이를 이용한 IMP 생산 방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999003988A1 (fr) * 1997-07-18 1999-01-28 Ajinomoto Co., Inc. Procede de production de nucleosides de purine par fermentation
RU2326170C2 (ru) * 1999-07-01 2008-06-10 Басф Акциенгезелльшафт Гены corynebacterium glutamicum, кодирующие белки системы фосфоенолпируват-сахар-фосфотрансферазы
KR100542568B1 (ko) 2003-12-10 2006-01-11 씨제이 주식회사 5'-크산틸산을 생산하는 미생물
AU2006219823A1 (en) * 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
KR20070056491A (ko) * 2005-11-30 2007-06-04 씨제이 주식회사 포스포리보실 피로포스페이트 아미도트랜스퍼라제 코딩유전자가 도입된 미생물 및 이를 사용한 ５’-크산틸산의생산방법
WO2008033001A1 (en) 2006-09-15 2008-03-20 Cj Cheiljedang Corporation A corynebacteria having enhanced l-lysine productivity and a method of producing l-lysine using the same
KR101166027B1 (ko) * 2009-04-01 2012-07-19 씨제이제일제당 (주) 5'-이노신산 생산성이 향상된 코리네박테리움 속 미생물 및 이를 이용한 핵산의 생산방법
CN103952422B (zh) * 2014-04-15 2016-06-29 天津大学 枯草芽孢杆菌编码PRPP转酰胺酶突变基因purF及应用
KR101904675B1 (ko) 2017-12-15 2018-10-04 씨제이제일제당 (주) 5'-이노신산을 생산하는 미생물 및 이를 이용한 5'-이노신산의 생산 방법
KR101950141B1 (ko) * 2018-08-01 2019-02-19 씨제이제일제당 (주) 신규 아데닐로석시네이트 신세타아제 및 이를 이용한 퓨린 뉴클레오티드 생산방법

Also Published As

Publication number Publication date
US20210047666A1 (en) 2021-02-18
KR102006977B1 (ko) 2019-08-05
JP2021512586A (ja) 2021-05-20
MY192935A (en) 2022-09-15
EP3739044A1 (en) 2020-11-18
RU2736372C1 (ru) 2020-11-16
US11008599B2 (en) 2021-05-18
EP3739044A4 (en) 2021-01-27
ZA201905668B (en) 2020-05-27
TWI738050B (zh) 2021-09-01
AU2019226146A1 (en) 2020-10-15
HUE063033T2 (hu) 2024-01-28
CN112004926A (zh) 2020-11-27
CN112004926B (zh) 2021-11-12
PT3739044T (pt) 2023-09-13
JP6891292B2 (ja) 2021-06-18
AU2019226146B2 (en) 2021-10-28
EP3739044B1 (en) 2023-07-12
PL3739044T3 (pl) 2023-10-30
BR112019020178A2 (pt) 2021-10-26
ES2955417T3 (es) 2023-11-30
TW202035686A (zh) 2020-10-01
SG11201907885WA (en) 2020-11-27
WO2020196993A1 (ko) 2020-10-01
BR112019020178B1 (pt) 2022-11-01

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