PT3739044T - Variante de fosforibosilpirofosfato amidotransferase e método para produzir nucleótido de purina por utilização da mesma - Google Patents
Variante de fosforibosilpirofosfato amidotransferase e método para produzir nucleótido de purina por utilização da mesmaInfo
- Publication number
- PT3739044T PT3739044T PT197627003T PT19762700T PT3739044T PT 3739044 T PT3739044 T PT 3739044T PT 197627003 T PT197627003 T PT 197627003T PT 19762700 T PT19762700 T PT 19762700T PT 3739044 T PT3739044 T PT 3739044T
- Authority
- PT
- Portugal
- Prior art keywords
- variant
- same
- purine nucleotide
- phosphoribosyl pyrophosphate
- pyrophosphate amidotransferase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/02014—Amidophosphoribosyltransferase (2.4.2.14)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020190035683A KR102006977B1 (ko) | 2019-03-28 | 2019-03-28 | 변이형 포스포리보실피로포스페이트 아미도트랜스퍼라아제 및 이를 이용한 퓨린 뉴클레오티드 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3739044T true PT3739044T (pt) | 2023-09-13 |
Family
ID=67616121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT197627003T PT3739044T (pt) | 2019-03-28 | 2019-07-19 | Variante de fosforibosilpirofosfato amidotransferase e método para produzir nucleótido de purina por utilização da mesma |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11008599B2 (pt) |
| EP (1) | EP3739044B1 (pt) |
| JP (1) | JP6891292B2 (pt) |
| KR (1) | KR102006977B1 (pt) |
| CN (1) | CN112004926B (pt) |
| AU (1) | AU2019226146B2 (pt) |
| BR (1) | BR112019020178B1 (pt) |
| ES (1) | ES2955417T3 (pt) |
| HU (1) | HUE063033T2 (pt) |
| MX (1) | MX2019011479A (pt) |
| MY (1) | MY192935A (pt) |
| PL (1) | PL3739044T3 (pt) |
| PT (1) | PT3739044T (pt) |
| RU (1) | RU2736372C1 (pt) |
| SG (1) | SG11201907885WA (pt) |
| TW (1) | TWI738050B (pt) |
| WO (1) | WO2020196993A1 (pt) |
| ZA (1) | ZA201905668B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100771511B1 (ko) * | 2006-03-09 | 2007-10-30 | 삼성코닝 주식회사 | 분할 구동용 백 라이트 유닛 및 그 백 라이트 유닛의비대칭 발광 다이오드 렌즈 |
| KR102013873B1 (ko) | 2018-01-25 | 2019-08-23 | 씨제이제일제당 주식회사 | 퓨린 뉴클레오티드를 생산하는 코리네박테리움 속 미생물 및 이를 이용한 퓨린 뉴클레오티드의 생산방법 |
| CN113106080B (zh) * | 2021-03-31 | 2022-02-25 | 深圳希吉亚生物技术有限公司 | 烟酰胺磷酸核糖转移酶突变体及其应用 |
| KR102277410B1 (ko) * | 2021-04-29 | 2021-07-14 | 씨제이제일제당 주식회사 | 신규한 이중기능성 pyr 오페론 전사조절자/우라실 포스포리보실 전달 효소 변이체 및 이를 이용한 IMP 생산 방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3944916B2 (ja) * | 1997-07-18 | 2007-07-18 | 味の素株式会社 | 発酵法によるプリンヌクレオシドの製造法 |
| RU2326170C2 (ru) * | 1999-07-01 | 2008-06-10 | Басф Акциенгезелльшафт | Гены corynebacterium glutamicum, кодирующие белки системы фосфоенолпируват-сахар-фосфотрансферазы |
| KR100542568B1 (ko) | 2003-12-10 | 2006-01-11 | 씨제이 주식회사 | 5'-크산틸산을 생산하는 미생물 |
| EP1871883A1 (en) * | 2005-03-02 | 2008-01-02 | Metanomics GmbH | Process for the production of fine chemicals |
| KR20070056491A (ko) * | 2005-11-30 | 2007-06-04 | 씨제이 주식회사 | 포스포리보실 피로포스페이트 아미도트랜스퍼라제 코딩유전자가 도입된 미생물 및 이를 사용한 ５’-크산틸산의생산방법 |
| KR100924065B1 (ko) | 2006-09-15 | 2009-10-27 | 씨제이제일제당 (주) | Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를 이용한 ｌ－라이신 생산 방법 |
| KR101166027B1 (ko) * | 2009-04-01 | 2012-07-19 | 씨제이제일제당 (주) | 5'-이노신산 생산성이 향상된 코리네박테리움 속 미생물 및 이를 이용한 핵산의 생산방법 |
| CN103952422B (zh) * | 2014-04-15 | 2016-06-29 | 天津大学 | 枯草芽孢杆菌编码PRPP转酰胺酶突变基因purF及应用 |
| KR101904675B1 (ko) | 2017-12-15 | 2018-10-04 | 씨제이제일제당 (주) | 5'-이노신산을 생산하는 미생물 및 이를 이용한 5'-이노신산의 생산 방법 |
| KR101950141B1 (ko) * | 2018-08-01 | 2019-02-19 | 씨제이제일제당 (주) | 신규 아데닐로석시네이트 신세타아제 및 이를 이용한 퓨린 뉴클레오티드 생산방법 |
-
2019
- 2019-03-28 KR KR1020190035683A patent/KR102006977B1/ko active IP Right Grant
- 2019-07-19 EP EP19762700.3A patent/EP3739044B1/en active Active
- 2019-07-19 HU HUE19762700A patent/HUE063033T2/hu unknown
- 2019-07-19 BR BR112019020178-5A patent/BR112019020178B1/pt active IP Right Grant
- 2019-07-19 CN CN201980002191.6A patent/CN112004926B/zh active Active
- 2019-07-19 WO PCT/KR2019/008924 patent/WO2020196993A1/ko unknown
- 2019-07-19 PT PT197627003T patent/PT3739044T/pt unknown
- 2019-07-19 ES ES19762700T patent/ES2955417T3/es active Active
- 2019-07-19 JP JP2019549374A patent/JP6891292B2/ja active Active
- 2019-07-19 AU AU2019226146A patent/AU2019226146B2/en active Active
- 2019-07-19 RU RU2019127999A patent/RU2736372C1/ru active
- 2019-07-19 SG SG11201907885WA patent/SG11201907885WA/en unknown
- 2019-07-19 MX MX2019011479A patent/MX2019011479A/es unknown
- 2019-07-19 US US16/493,661 patent/US11008599B2/en active Active
- 2019-07-19 PL PL19762700.3T patent/PL3739044T3/pl unknown
- 2019-08-28 ZA ZA2019/05668A patent/ZA201905668B/en unknown
- 2019-08-29 MY MYPI2019004993A patent/MY192935A/en unknown
- 2019-09-04 TW TW108131886A patent/TWI738050B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| HUE063033T2 (hu) | 2024-01-28 |
| CN112004926A (zh) | 2020-11-27 |
| SG11201907885WA (en) | 2020-11-27 |
| BR112019020178A2 (pt) | 2021-10-26 |
| MY192935A (en) | 2022-09-15 |
| BR112019020178B1 (pt) | 2022-11-01 |
| JP2021512586A (ja) | 2021-05-20 |
| TWI738050B (zh) | 2021-09-01 |
| US20210047666A1 (en) | 2021-02-18 |
| JP6891292B2 (ja) | 2021-06-18 |
| MX2019011479A (es) | 2020-11-13 |
| ES2955417T3 (es) | 2023-11-30 |
| ZA201905668B (en) | 2020-05-27 |
| WO2020196993A1 (ko) | 2020-10-01 |
| EP3739044B1 (en) | 2023-07-12 |
| AU2019226146A1 (en) | 2020-10-15 |
| RU2736372C1 (ru) | 2020-11-16 |
| EP3739044A1 (en) | 2020-11-18 |
| TW202035686A (zh) | 2020-10-01 |
| KR102006977B1 (ko) | 2019-08-05 |
| US11008599B2 (en) | 2021-05-18 |
| PL3739044T3 (pl) | 2023-10-30 |
| CN112004926B (zh) | 2021-11-12 |
| EP3739044A4 (en) | 2021-01-27 |
| AU2019226146B2 (en) | 2021-10-28 |
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