AR101434A1 - Método para producir (r)-1,1,3-trimetil-4-aminoindano - Google Patents
Método para producir (r)-1,1,3-trimetil-4-aminoindanoInfo
- Publication number
- AR101434A1 AR101434A1 ARP150100281A ARP150100281A AR101434A1 AR 101434 A1 AR101434 A1 AR 101434A1 AR P150100281 A ARP150100281 A AR P150100281A AR P150100281 A ARP150100281 A AR P150100281A AR 101434 A1 AR101434 A1 AR 101434A1
- Authority
- AR
- Argentina
- Prior art keywords
- trimethyl
- aminoindane
- producing
- aminoindano
- trimetil
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/84—Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/86—Separation
- C07C209/88—Separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/90—Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/57—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton
- C07C211/60—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems of the carbon skeleton containing a ring other than a six-membered aromatic ring forming part of at least one of the condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
Se ha demandado un método de producción para obtener (R)-1,1,3-trimetil-4-aminoindano en un alto rendimiento. El método para producir (R)-1,1,3-trimetil-4-aminoindano incluye las siguientes etapas (A), (B) y (C): (A): una etapa de resolución óptica 1,1,3-trimetil-4-aminoindano para obtener (R)-1,1,3-trimetil-4-aminoindano y (S)-1,1,3-trimetil-4-aminoindano; (B): una etapa de racemización del (S)-1,1,3-trimetil-4-aminoindano obtenido en la etapa (A) o (C) para obtener 1,1,3-trimetil-4-aminoindano; y (C): una etapa de resolución óptica el 1,1,3-trimetil-4-aminoindano obtenido en la etapa (B) para obtener (R)-1,1,3-trimetil-4-aminoindano y (S)-1,1,3-trimetil-4-aminoindano.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014021976 | 2014-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR101434A1 true AR101434A1 (es) | 2016-12-21 |
Family
ID=53777608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150100281A AR101434A1 (es) | 2014-02-07 | 2015-01-30 | Método para producir (r)-1,1,3-trimetil-4-aminoindano |
Country Status (14)
Country | Link |
---|---|
US (1) | US9765032B2 (es) |
EP (1) | EP3103789B1 (es) |
JP (1) | JP6451652B2 (es) |
KR (1) | KR102264639B1 (es) |
CN (1) | CN105992755B (es) |
AR (1) | AR101434A1 (es) |
AU (1) | AU2014381760B2 (es) |
BR (1) | BR112016017648B1 (es) |
DK (1) | DK3103789T3 (es) |
ES (1) | ES2702891T3 (es) |
IL (1) | IL246923B (es) |
RU (1) | RU2016135762A (es) |
TW (1) | TWI646071B (es) |
WO (1) | WO2015118793A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CR20200237A (es) | 2012-10-12 | 2020-07-26 | Exelixis Inc | Proceso novedoso para la elaboración de compuestos para su uso en el tratamiento del cáncer (diviisional 2015-0245) |
CN110891940A (zh) * | 2017-08-28 | 2020-03-17 | 日本凡凯姆股份有限公司 | 吡唑-4-甲酰胺衍生物的制备方法 |
ES2965832T3 (es) | 2018-03-26 | 2024-04-17 | Bayer Ag | Hidrogenación enantioselectiva de 1,2-dihidroquinolinas 4-sustituidas en presencia de un catalizador quiral de iridio |
JP2022549636A (ja) | 2019-09-25 | 2022-11-28 | バイエル・アクチエンゲゼルシヤフト | 4-置換1,2-ジヒドロキノリン類のエナンチオ選択的水素化のための新規イリジウム触媒の使用を含む方法 |
EP4034527A1 (en) | 2019-09-25 | 2022-08-03 | Bayer Aktiengesellschaft | Improved enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst and an additive |
IT201900017330A1 (it) * | 2019-09-26 | 2021-03-26 | Isagro Spa | Processo per la preparazione di (r)-4-amminoindani e corrispondenti ammidi. |
AU2020373798A1 (en) * | 2019-11-01 | 2022-06-02 | Sumitomo Chemical Company, Limited | Crystal of 3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide |
US20230257408A1 (en) | 2020-07-17 | 2023-08-17 | Sumitomo Chemical Company, Limited | Method for producing optically active compound |
JP2023120459A (ja) * | 2020-07-17 | 2023-08-30 | 住友化学株式会社 | 光学活性な1,1,3-トリメチル-4-アミノインダンの製造方法 |
CN114773263B (zh) * | 2022-05-16 | 2023-09-05 | 江苏百康德医药科技有限公司 | (r)-2,2,4-三甲基-1,2,3,4-四氢喹啉的制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5093347A (en) | 1991-01-28 | 1992-03-03 | Monsanto Company | 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use |
US5521317A (en) * | 1993-10-22 | 1996-05-28 | American Cyanamid Co. | Processes for the preparation of pesticides and intermediates |
JP3892503B2 (ja) * | 1996-09-02 | 2007-03-14 | 長瀬産業株式会社 | 接触還元触媒を用いる光学活性アミンのラセミ化法 |
JP4834333B2 (ja) * | 2005-06-27 | 2011-12-14 | アルプス薬品工業株式会社 | 光学活性ベンジルアミン誘導体の製造方法 |
JP2011012032A (ja) * | 2009-07-03 | 2011-01-20 | Yamakawa Yakuhin Kogyo Kk | 光学活性な3−アミノピペリジンの製造方法および製造の中間体 |
JP2012025735A (ja) * | 2010-06-24 | 2012-02-09 | Sumitomo Chemical Co Ltd | 植物病害防除組成物及び植物病害防除方法 |
JP6106976B2 (ja) | 2012-07-20 | 2017-04-05 | 住友化学株式会社 | 植物病害防除組成物およびその用途 |
WO2014034957A1 (ja) * | 2012-08-31 | 2014-03-06 | 住友化学株式会社 | (r)-1,1,3-トリメチル-4-アミノインダンの製造方法 |
CN104768918B (zh) | 2012-11-02 | 2017-03-08 | 住友化学株式会社 | 化合物的外消旋体的制造方法 |
WO2014103812A1 (ja) | 2012-12-25 | 2014-07-03 | 住友化学株式会社 | ピラゾール化合物の結晶の製造方法 |
BR112015015097B1 (pt) | 2012-12-27 | 2021-02-17 | Sumitomo Chemical Company, Limited | método para produção de composto de amina purificada |
-
2014
- 2014-12-26 WO PCT/JP2014/084766 patent/WO2015118793A1/ja active Application Filing
- 2014-12-26 BR BR112016017648-0A patent/BR112016017648B1/pt active IP Right Grant
- 2014-12-26 AU AU2014381760A patent/AU2014381760B2/en active Active
- 2014-12-26 RU RU2016135762A patent/RU2016135762A/ru not_active Application Discontinuation
- 2014-12-26 JP JP2015561187A patent/JP6451652B2/ja active Active
- 2014-12-26 EP EP14882034.3A patent/EP3103789B1/en active Active
- 2014-12-26 CN CN201480075004.4A patent/CN105992755B/zh active Active
- 2014-12-26 KR KR1020167021175A patent/KR102264639B1/ko active IP Right Grant
- 2014-12-26 US US15/117,058 patent/US9765032B2/en active Active
- 2014-12-26 ES ES14882034T patent/ES2702891T3/es active Active
- 2014-12-26 DK DK14882034.3T patent/DK3103789T3/en active
-
2015
- 2015-01-09 TW TW104100693A patent/TWI646071B/zh active
- 2015-01-30 AR ARP150100281A patent/AR101434A1/es active IP Right Grant
-
2016
- 2016-07-25 IL IL246923A patent/IL246923B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CN105992755B (zh) | 2018-07-13 |
KR102264639B1 (ko) | 2021-06-11 |
DK3103789T3 (en) | 2019-01-28 |
IL246923A0 (en) | 2016-09-29 |
US9765032B2 (en) | 2017-09-19 |
KR20160118256A (ko) | 2016-10-11 |
WO2015118793A1 (ja) | 2015-08-13 |
JP6451652B2 (ja) | 2019-01-16 |
EP3103789A1 (en) | 2016-12-14 |
IL246923B (en) | 2020-08-31 |
AU2014381760B2 (en) | 2018-08-02 |
JPWO2015118793A1 (ja) | 2017-03-23 |
TWI646071B (zh) | 2019-01-01 |
RU2016135762A3 (es) | 2018-08-01 |
EP3103789B1 (en) | 2018-10-31 |
RU2016135762A (ru) | 2018-03-14 |
TW201612153A (en) | 2016-04-01 |
ES2702891T3 (es) | 2019-03-06 |
BR112016017648B1 (pt) | 2021-01-19 |
US20170166532A1 (en) | 2017-06-15 |
CN105992755A (zh) | 2016-10-05 |
AU2014381760A1 (en) | 2016-08-18 |
EP3103789A4 (en) | 2017-07-05 |
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