MX2020004869A - Metodo para preparar derivado de benzofurano. - Google Patents

Metodo para preparar derivado de benzofurano.

Info

Publication number
MX2020004869A
MX2020004869A MX2020004869A MX2020004869A MX2020004869A MX 2020004869 A MX2020004869 A MX 2020004869A MX 2020004869 A MX2020004869 A MX 2020004869A MX 2020004869 A MX2020004869 A MX 2020004869A MX 2020004869 A MX2020004869 A MX 2020004869A
Authority
MX
Mexico
Prior art keywords
preparing
benzofuran derivative
benzofuran
derivative
synthesize
Prior art date
Application number
MX2020004869A
Other languages
English (en)
Other versions
MX395591B (es
Inventor
Chao Xu
Feng He
Qiyun Shao
Weidong Lu
Haoyu Zhang
Jun Feng
Original Assignee
Jiangsu Hengrui Medicine Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hengrui Medicine Co filed Critical Jiangsu Hengrui Medicine Co
Publication of MX2020004869A publication Critical patent/MX2020004869A/es
Publication of MX395591B publication Critical patent/MX395591B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se describe un metodo para preparar un derivado de benzofurano; en particular, se proporciona un metodo para preparar un derivado de benzofurano, en donde de acuerdo con el metodo provisto, los pasos de reacción requeridos para sintetizar la sustancia de benzofurano en la técnica antecedente pueden acortarse de manera eficaz.
MX2020004869A 2017-11-10 2018-11-09 Metodo para preparar derivado de benzofurano MX395591B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201711104888 2017-11-10
PCT/CN2018/114798 WO2019091450A1 (zh) 2017-11-10 2018-11-09 一种苯并呋喃衍生物的制备方法

Publications (2)

Publication Number Publication Date
MX2020004869A true MX2020004869A (es) 2020-08-06
MX395591B MX395591B (es) 2025-03-25

Family

ID=66438760

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020004869A MX395591B (es) 2017-11-10 2018-11-09 Metodo para preparar derivado de benzofurano

Country Status (8)

Country Link
US (1) US11390614B2 (es)
EP (1) EP3708567A4 (es)
JP (2) JP7295105B6 (es)
CN (1) CN111094279B (es)
AU (2) AU2018363467B2 (es)
MX (1) MX395591B (es)
TW (1) TWI717656B (es)
WO (1) WO2019091450A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020228591A1 (zh) * 2019-05-10 2020-11-19 江苏恒瑞医药股份有限公司 一种6-取代氨基苯并呋喃化合物的制备方法
CN114456156A (zh) * 2020-11-09 2022-05-10 江苏恒瑞医药股份有限公司 一种6-取代氨基苯并呋喃化合物的纯化方法
IL312137A (en) 2021-10-15 2024-06-01 Jiangsu Hengrui Pharmaceuticals Co Ltd A method of preparation of a benzofuran derivative
CN113861002B (zh) * 2021-11-02 2024-04-26 琼台师范学院 一种无金属催化体系催化氧化芳香醇类制备芳香酮类化合物的方法
IL317228A (en) 2022-06-13 2025-01-01 Treeline Biosciences Inc BCL6 quinolone bifunctional joints
CA3258412A1 (en) 2022-06-13 2023-12-21 Treeline Biosciences, Inc. HETEROBORCTIONAL BCL6 DEGRADING AGENTS 1,8-NAPHTHYRIDIN-2-ONE
WO2024260368A1 (zh) * 2023-06-19 2024-12-26 江苏恒瑞医药股份有限公司 一种苯并呋喃衍生物及其中间体的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236625A (en) * 1963-07-18 1966-02-22 Tenneco Chem Method of inhibiting plant growth
JP3233678B2 (ja) 1991-06-27 2001-11-26 日本化学工業株式会社 ｏ−アルコキシ安息香酸の製造方法
PT923568E (pt) 1996-08-19 2003-04-30 Altana Pharma Ag Novas benzofuran-4-carboxamidas
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
WO2001083421A1 (en) 2000-04-28 2001-11-08 Nihon Nohyaku Co., Ltd. Process for the preparation of 2-halobenzoic acids
WO2002010156A1 (en) 2000-07-29 2002-02-07 Arpida Ag Benzofuran derivatives and their use as antibacterial agents
FR2923826A1 (fr) 2007-11-21 2009-05-22 Ppg Sipsy Soc Par Actions Simp Procede de synthese de l'acide 4-benzofurane carboxylique
CN101434582A (zh) * 2008-11-28 2009-05-20 华东理工大学 苯甲酸(苯并三唑基)苯酯类化合物
ES2534804T3 (es) 2010-05-07 2015-04-28 Glaxosmithkline Llc Indazoles
TW201733984A (zh) 2011-04-13 2017-10-01 雅酶股份有限公司 經取代之苯化合物
ES2624986T3 (es) 2011-09-13 2017-07-18 Glaxosmithkline Llc Azaindazoles
SI3121175T1 (sl) 2014-03-17 2020-07-31 Daiichi Sankyo Company, Limited Derivati 1,3-benzodioksola kot EZH1 in/ali EZH2 inhibitorji
LT3378859T (lt) 2015-11-19 2020-01-27 Jiangsu Hengrui Medicine Co., Ltd. Benzofurano darinys, jo gavimo būdas ir jo panaudojimas medicinoje

Also Published As

Publication number Publication date
AU2023278061A1 (en) 2024-01-04
JP7295105B6 (ja) 2023-07-24
EP3708567A1 (en) 2020-09-16
JP2023123543A (ja) 2023-09-05
JP2021502376A (ja) 2021-01-28
RU2020118301A (ru) 2021-12-10
WO2019091450A1 (zh) 2019-05-16
JP7526856B2 (ja) 2024-08-01
AU2018363467A1 (en) 2020-06-04
CN111094279A (zh) 2020-05-01
US20210188822A1 (en) 2021-06-24
CN111094279B (zh) 2023-06-16
AU2023278061B2 (en) 2025-11-13
TW201918469A (zh) 2019-05-16
EP3708567A4 (en) 2021-07-07
MX395591B (es) 2025-03-25
TWI717656B (zh) 2021-02-01
US11390614B2 (en) 2022-07-19
AU2018363467B2 (en) 2023-09-07
JP7295105B2 (ja) 2023-06-20
RU2020118301A3 (es) 2022-01-27

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