BR112017002139A2 - ?método para preparar um composto? - Google Patents

?método para preparar um composto?

Info

Publication number
BR112017002139A2
BR112017002139A2 BR112017002139A BR112017002139A BR112017002139A2 BR 112017002139 A2 BR112017002139 A2 BR 112017002139A2 BR 112017002139 A BR112017002139 A BR 112017002139A BR 112017002139 A BR112017002139 A BR 112017002139A BR 112017002139 A2 BR112017002139 A2 BR 112017002139A2
Authority
BR
Brazil
Prior art keywords
preparing
compound
methods
following compound
following
Prior art date
Application number
BR112017002139A
Other languages
English (en)
Other versions
BR112017002139B1 (pt
Inventor
Liu Bing
Guo Jiasheng
B Mitchell Mark
t martin Michael
Zhou Xiaoming
Original Assignee
Glaxosmithkline Ip No 2 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip No 2 Ltd filed Critical Glaxosmithkline Ip No 2 Ltd
Publication of BR112017002139A2 publication Critical patent/BR112017002139A2/pt
Publication of BR112017002139B1 publication Critical patent/BR112017002139B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

são descritos métodos para preparar o composto a seguir.
BR112017002139-0A 2014-08-05 2015-07-23 método para preparar um composto BR112017002139B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462033181P 2014-08-05 2014-08-05
US62/033,181 2014-08-05
PCT/IB2015/055584 WO2016020785A1 (en) 2014-08-05 2015-07-23 Synthesis of benzothiazepines

Publications (2)

Publication Number Publication Date
BR112017002139A2 true BR112017002139A2 (pt) 2017-11-21
BR112017002139B1 BR112017002139B1 (pt) 2021-02-09

Family

ID=53773475

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017002139-0A BR112017002139B1 (pt) 2014-08-05 2015-07-23 método para preparar um composto

Country Status (11)

Country Link
US (1) US9834529B2 (pt)
EP (1) EP3177600B1 (pt)
JP (1) JP6543330B2 (pt)
KR (1) KR20170039195A (pt)
CN (1) CN106687451B (pt)
AU (1) AU2015298377B2 (pt)
BR (1) BR112017002139B1 (pt)
CA (1) CA2956833C (pt)
ES (1) ES2682171T3 (pt)
RU (1) RU2017105217A (pt)
WO (1) WO2016020785A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3475266B1 (en) * 2016-06-27 2023-09-06 GlaxoSmithKline Intellectual Property (No. 2) Limited Synthetic methods
CA3129735A1 (en) 2019-02-12 2020-08-20 Mirum Pharmaceuticals, Inc. Methods for increasing growth in pediatric subjects having cholestatic liver disease
WO2022084212A1 (en) 2020-10-20 2022-04-28 Glaxosmithkline Intellectual Property (No.2) Limited Methods for treating cholestatic pruritus
CN116964041A (zh) 2020-12-23 2023-10-27 葛兰素史克知识产权第二有限公司 Linerixibat的形式

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL108634A0 (en) 1993-02-15 1994-05-30 Wellcome Found Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
ZA956647B (en) * 1994-08-10 1997-02-10 Wellcome Found Hypolipidaemic compounds.
JO3131B1 (ar) * 2010-04-27 2017-09-20 Glaxosmithkline Llc مركبات كيميائية

Also Published As

Publication number Publication date
EP3177600B1 (en) 2018-05-23
CN106687451B (zh) 2018-11-16
JP6543330B2 (ja) 2019-07-10
WO2016020785A1 (en) 2016-02-11
AU2015298377B2 (en) 2017-11-02
RU2017105217A (ru) 2018-09-06
KR20170039195A (ko) 2017-04-10
US20170210717A1 (en) 2017-07-27
CN106687451A (zh) 2017-05-17
JP2017523212A (ja) 2017-08-17
AU2015298377A1 (en) 2017-02-23
CA2956833C (en) 2022-08-30
US9834529B2 (en) 2017-12-05
RU2017105217A3 (pt) 2018-11-30
BR112017002139B1 (pt) 2021-02-09
CA2956833A1 (en) 2016-02-11
EP3177600A1 (en) 2017-06-14
ES2682171T3 (es) 2018-09-19

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/07/2015, OBSERVADAS AS CONDICOES LEGAIS.