BR112016023337A2 - microrganismo tendo capacidade de produção de l-lisina e método de produção de l-lisina utilizando o mesmo - Google Patents

microrganismo tendo capacidade de produção de l-lisina e método de produção de l-lisina utilizando o mesmo

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Publication number
BR112016023337A2
BR112016023337A2 BR112016023337-9A BR112016023337A BR112016023337A2 BR 112016023337 A2 BR112016023337 A2 BR 112016023337A2 BR 112016023337 A BR112016023337 A BR 112016023337A BR 112016023337 A2 BR112016023337 A2 BR 112016023337A2
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BR
Brazil
Prior art keywords
lysine
producing
same
microorganism
ability
Prior art date
Application number
BR112016023337-9A
Other languages
English (en)
Korean (ko)
Other versions
BR112016023337B1 (pt
Inventor
Won Bae Hyun
Ok Moon Jun
Ki Song Sung
Joon Kim Hyung
Jin Kim Hyo
Jo Lim Sang
Original Assignee
Cj Cheiljedang Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corporation filed Critical Cj Cheiljedang Corporation
Publication of BR112016023337A2 publication Critical patent/BR112016023337A2/pt
Publication of BR112016023337B1 publication Critical patent/BR112016023337B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02001Acetate kinase (2.7.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15Corynebacterium

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

resumo da patente de invenção para: "microrganismo tendo capacidade de produção de l-lisina e método de produção de l-lisina utilizando o mesmo". a presente invenção se refere a um microrganismo com capacidade melhorada de produção de l-lisina e a um método de produção de l-lisina utilizando o mesmo. mais especificamente, a presente invenção se refere a um microrganismo do gênero corynebacterium, no qual a atividade do acetato quinase é adicionalmente amplificada em relação à atividade inerente e a um método de produção de l-lisina produtoras utilizando o mesmo.
BR112016023337-9A 2014-04-09 2015-04-07 Microrganismo tendo capacidade de produção de l-lisina e método de produção de l-lisina utilizando o mesmo BR112016023337B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2014-0042397 2014-04-09
KR1020140042397A KR101601404B1 (ko) 2014-04-09 2014-04-09 L-라이신 생산능을 갖는 미생물 및 이를 이용한 l-라이신 생산 방법
PCT/KR2015/003478 WO2015156583A1 (ko) 2014-04-09 2015-04-07 L-라이신 생산능을 갖는 미생물 및 이를 이용한 l-라이신 생산 방법

Publications (2)

Publication Number Publication Date
BR112016023337A2 true BR112016023337A2 (pt) 2018-01-16
BR112016023337B1 BR112016023337B1 (pt) 2023-10-17

Family

ID=54288096

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016023337-9A BR112016023337B1 (pt) 2014-04-09 2015-04-07 Microrganismo tendo capacidade de produção de l-lisina e método de produção de l-lisina utilizando o mesmo

Country Status (12)

Country Link
US (1) US10179903B2 (pt)
EP (1) EP3130663B1 (pt)
JP (2) JP6495940B2 (pt)
KR (1) KR101601404B1 (pt)
CN (1) CN106574232B (pt)
BR (1) BR112016023337B1 (pt)
ES (1) ES2855048T3 (pt)
HU (1) HUE053437T2 (pt)
MY (1) MY195658A (pt)
PL (1) PL3130663T3 (pt)
RU (1) RU2694729C2 (pt)
WO (1) WO2015156583A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3613850A1 (en) * 2018-08-22 2020-02-26 Evonik Operations GmbH Amino acid production
WO2020169547A1 (de) 2019-02-20 2020-08-27 Basf Se Thermoplastische formmasse
WO2020173766A1 (de) 2019-02-25 2020-09-03 Basf Se Thermoplastische formmasse
KR102271333B1 (ko) * 2021-01-29 2021-06-30 씨제이제일제당 (주) 신규한 미코티온 리덕타제 변이체 및 이를 이용한 l-라이신 생산 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR940001307B1 (ko) 1991-12-27 1994-02-19 제일제당 주식회사 L-라이신을 생산하는 신규 미생물
KR0159812B1 (ko) 1995-12-20 1998-11-16 손경식 코리네박테리움 글루타미컴 씨에이치 77 및 이 균주를 이용한 l-라이신의 제조 방법
KR100397322B1 (ko) 2000-12-30 2003-09-06 씨제이 주식회사 엘-라이신의 제조방법
ATE443757T1 (de) * 2004-01-30 2009-10-15 Ajinomoto Kk L-aminosäure produzierender mikroorganismus und verfahren zur l-aminosäureproduktion
KR100789271B1 (ko) * 2005-11-30 2008-01-02 씨제이 주식회사 L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 l-라이신을 생산하는 방법
JP5157180B2 (ja) * 2006-01-27 2013-03-06 味の素株式会社 L−アミノ酸の製造法
PE20071235A1 (es) 2006-01-27 2007-12-02 Ajinomoto Kk Metodo para producir l-amino acidos
JP2009060791A (ja) 2006-03-30 2009-03-26 Ajinomoto Co Inc L−アミノ酸生産菌及びl−アミノ酸の製造法
AU2007295159B2 (en) 2006-09-15 2012-09-13 Cj Cheiljedang Corporation A Corynebacteria having enhanced L-lysine productivity and a method of producing L-lysine using the same
KR100838035B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 l-라이신 생산 방법
KR100930203B1 (ko) 2008-01-28 2009-12-07 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 l-라이신의 생산 방법
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 l-라이신 생산방법

Also Published As

Publication number Publication date
JP6495940B2 (ja) 2019-04-03
KR101601404B1 (ko) 2016-03-09
EP3130663A1 (en) 2017-02-15
RU2694729C2 (ru) 2019-07-16
ES2855048T3 (es) 2021-09-23
US20180135031A1 (en) 2018-05-17
EP3130663A4 (en) 2017-08-30
RU2016141594A (ru) 2018-05-10
EP3130663B1 (en) 2020-11-18
BR112016023337B1 (pt) 2023-10-17
MY195658A (en) 2023-02-03
RU2016141594A3 (pt) 2018-05-10
CN106574232B (zh) 2020-03-20
HUE053437T2 (hu) 2021-06-28
KR20150117337A (ko) 2015-10-20
JP2019030316A (ja) 2019-02-28
JP2017510280A (ja) 2017-04-13
CN106574232A (zh) 2017-04-19
WO2015156583A1 (ko) 2015-10-15
PL3130663T3 (pl) 2021-10-25
US10179903B2 (en) 2019-01-15

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B06A Patent application procedure suspended [chapter 6.1 patent gazette]
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B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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