BR112017026005A2 - ?polipeptídeo, polinucleotídeo, micro-organismo do gênero escherichia, método de produção de o- acetil-homosserina e de l-metionina? - Google Patents

?polipeptídeo, polinucleotídeo, micro-organismo do gênero escherichia, método de produção de o- acetil-homosserina e de l-metionina?

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Publication number
BR112017026005A2
BR112017026005A2 BR112017026005-0A BR112017026005A BR112017026005A2 BR 112017026005 A2 BR112017026005 A2 BR 112017026005A2 BR 112017026005 A BR112017026005 A BR 112017026005A BR 112017026005 A2 BR112017026005 A2 BR 112017026005A2
Authority
BR
Brazil
Prior art keywords
acetyl
organism
micro
homoserine
production
Prior art date
Application number
BR112017026005-0A
Other languages
English (en)
Inventor
Yeon Bae Jee
Hyun Shim Ji
Ah Kim Hyun
Seo Juhee
Uk Shin Yong
Hee Lee Jae
Kyoum Kim Sang
Young Kim So
Original Assignee
Cj Cheiljedang Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corporation filed Critical Cj Cheiljedang Corporation
Publication of BR112017026005A2 publication Critical patent/BR112017026005A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01011—Aspartate-semialdehyde dehydrogenase (1.2.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/01—Oxidoreductases acting on NADH or NADPH (1.6) with NAD+ or NADP+ as acceptor (1.6.1)
    • C12Y106/01001—NAD(P)+ transhydrogenase (B-specific) (1.6.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01031—Homoserine O-acetyltransferase (2.3.1.31)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01039—Homoserine kinase (2.7.1.39)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

a presente revelação se refere a uma proteína que tem a atividade de exportar o-acetil-homosserina e uma proteína modificada inovadora do mesmo, um micro-organismo com a capacidade de produzir o-acetil-homosserina com expressão aprimorada da proteína e um método para produção de o-acetil-homosserina com o uso do micro-organismo.
BR112017026005-0A 2015-06-04 2016-06-03 ?polipeptídeo, polinucleotídeo, micro-organismo do gênero escherichia, método de produção de o- acetil-homosserina e de l-metionina? BR112017026005A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2015-0079358 2015-06-04
KR20150079358 2015-06-04
PCT/KR2016/005951 WO2016195439A1 (ko) 2015-06-04 2016-06-03 O-아세틸-호모세린을 생산하는 미생물 및 이를 이용하여 o-아세틸-호모세린을 생산하는 방법

Publications (1)

Publication Number Publication Date
BR112017026005A2 true BR112017026005A2 (pt) 2018-08-14

Family

ID=57440936

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017026005-0A BR112017026005A2 (pt) 2015-06-04 2016-06-03 ?polipeptídeo, polinucleotídeo, micro-organismo do gênero escherichia, método de produção de o- acetil-homosserina e de l-metionina?

Country Status (14)

Country Link
US (2) US10400256B2 (pt)
EP (1) EP3305808B1 (pt)
JP (1) JP6543734B2 (pt)
KR (1) KR101859276B1 (pt)
CN (1) CN108026147B (pt)
AU (1) AU2016271665B2 (pt)
BR (1) BR112017026005A2 (pt)
ES (1) ES2906229T3 (pt)
HU (1) HUE057284T2 (pt)
MY (1) MY174840A (pt)
PL (1) PL3305808T3 (pt)
RU (1) RU2706535C2 (pt)
SG (1) SG11201709899QA (pt)
WO (1) WO2016195439A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101996769B1 (ko) * 2018-12-21 2019-10-01 씨제이제일제당 (주) 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
KR102182497B1 (ko) * 2019-12-20 2020-11-24 씨제이제일제당 주식회사 내막 단백질의 변이체 및 이를 이용한 목적 산물 생산 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2175351C2 (ru) 1998-12-30 2001-10-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот
DE10305774A1 (de) * 2003-02-06 2004-08-26 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen Herstellung von L-Methionin
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
AR067318A1 (es) 2007-05-22 2009-10-07 Basf Plant Science Gmbh Plantas con mayor tolerancia y/o resistencia aumentada al estres ambiental y mayor produccion de biomasa
JP5343724B2 (ja) * 2008-06-18 2013-11-13 株式会社リコー 画像形成システム、画像形成システムの省電力制御方法、及び省電力制御プログラム
BRPI0918299B1 (pt) * 2008-09-08 2018-08-14 Ajinomoto Co., Inc. Método para produzir um l-aminoácido
JP5521347B2 (ja) * 2009-02-16 2014-06-11 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
US8283152B2 (en) 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
AR083468A1 (es) * 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
KR101335841B1 (ko) 2010-12-21 2013-12-02 씨제이제일제당 (주) 호모세린 아세틸 트랜스퍼라제 활성을 가지는 변이형 폴리펩티드 및 이를 발현하는 미생물
KR101250651B1 (ko) 2010-12-21 2013-04-03 씨제이제일제당 (주) 신규 ｏ-아세틸호모세린 설피드릴라제 또는 변이체 및 이를 이용한 메치오닌 전환 방법
MX2015012484A (es) * 2013-03-15 2016-04-20 Cargill Inc Mutaciones de acetil-coa carboxilasa.

Also Published As

Publication number Publication date
RU2706535C2 (ru) 2019-11-19
ES2906229T3 (es) 2022-04-13
PL3305808T3 (pl) 2022-04-04
SG11201709899QA (en) 2017-12-28
KR101859276B1 (ko) 2018-05-18
MY174840A (en) 2020-05-18
WO2016195439A1 (ko) 2016-12-08
JP2018517411A (ja) 2018-07-05
CN108026147B (zh) 2021-10-01
CN108026147A (zh) 2018-05-11
US20190338322A1 (en) 2019-11-07
EP3305808B1 (en) 2022-01-12
KR20160144017A (ko) 2016-12-15
AU2016271665B2 (en) 2019-05-09
RU2017144551A3 (pt) 2019-07-17
JP6543734B2 (ja) 2019-07-10
US20180135086A1 (en) 2018-05-17
US10400256B2 (en) 2019-09-03
US10597686B2 (en) 2020-03-24
EP3305808A4 (en) 2018-12-05
AU2016271665A1 (en) 2018-01-04
HUE057284T2 (hu) 2022-04-28
RU2017144551A (ru) 2019-07-09
EP3305808A1 (en) 2018-04-11

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