BR112017023756A2 - método de cultivar akkermansia - Google Patents

método de cultivar akkermansia

Info

Publication number
BR112017023756A2
BR112017023756A2 BR112017023756A BR112017023756A BR112017023756A2 BR 112017023756 A2 BR112017023756 A2 BR 112017023756A2 BR 112017023756 A BR112017023756 A BR 112017023756A BR 112017023756 A BR112017023756 A BR 112017023756A BR 112017023756 A2 BR112017023756 A2 BR 112017023756A2
Authority
BR
Brazil
Prior art keywords
muciniphila
akkermansia
cultivating
applications
humans
Prior art date
Application number
BR112017023756A
Other languages
English (en)
Inventor
Belzer Clara
Meindert De Vos Willem
Original Assignee
Univ Wageningen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wageningen filed Critical Univ Wageningen
Publication of BR112017023756A2 publication Critical patent/BR112017023756A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

um método para cultivar de modo eficaz em termos de custo e eficientemente akkermansia muciniphila é descrito. altos rendimentos de biomassa podem ser obtidos nos meios quimicamente definidos. isto permite a produção em larga escala de a. muciniphila adequada para o uso em seres humanos, tal como para aplicações farmacêuticas ou alimentícias. a a. muciniphila pode ser produzida livre de produtos derivados de animal, permitindo deste modo uma faixa ampla de aplicações.
BR112017023756A 2015-05-06 2016-05-04 método de cultivar akkermansia BR112017023756A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15166598 2015-05-06
PCT/EP2016/060039 WO2016177801A1 (en) 2015-05-06 2016-05-04 Method of culturing akkermansia

Publications (1)

Publication Number Publication Date
BR112017023756A2 true BR112017023756A2 (pt) 2018-07-31

Family

ID=53059006

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017023756A BR112017023756A2 (pt) 2015-05-06 2016-05-04 método de cultivar akkermansia

Country Status (15)

Country Link
US (2) US10988509B2 (pt)
EP (2) EP3292134B1 (pt)
JP (2) JP6925280B2 (pt)
KR (2) KR102615649B1 (pt)
CN (1) CN107849093B (pt)
AU (1) AU2016258976B2 (pt)
BR (1) BR112017023756A2 (pt)
CA (1) CA2984986C (pt)
DK (1) DK3292134T3 (pt)
EA (1) EA201700497A1 (pt)
HK (1) HK1252413A1 (pt)
IL (1) IL255406B (pt)
MX (1) MX2017014089A (pt)
PT (1) PT3292135T (pt)
WO (1) WO2016177801A1 (pt)

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Publication number Priority date Publication date Assignee Title
GB2551642B (en) 2014-10-31 2020-09-23 Pendulum Therapeutics Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
KR20180133443A (ko) * 2016-04-11 2018-12-14 바게닝겐 유니버시테이트 신규한 세균 종
CN107384828B (zh) * 2017-08-22 2020-06-16 中国农业科学院农产品加工研究所 阿克曼氏粘细菌培养基及其制备方法
WO2019046646A1 (en) 2017-08-30 2019-03-07 Whole Biome Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
JP6967404B2 (ja) * 2017-08-31 2021-11-17 雪印メグミルク株式会社 アッカーマンシア・ムシニフィラ増加促進用組成物
JP6993142B2 (ja) * 2017-08-31 2022-01-13 雪印メグミルク株式会社 アッカーマンシア・ムシニフィラ増加促進用組成物
CN107903310B (zh) * 2017-11-16 2021-02-05 广州佰斯伦生物技术有限公司 一种重组膜蛋白、微生物、含有其的组合物及应用
KR102197180B1 (ko) * 2018-10-11 2020-12-31 주식회사 고바이오랩 아커만시아 뮤시니필라 균주 및 이를 포함하는 식욕 억제 및 대사성 질환 예방, 개선, 완화 및 치료용 조성물
CN109355349B (zh) * 2018-11-30 2021-03-26 江南大学 一种阿克曼氏菌特异性筛选培养基及其制备方法和应用
CN109810931A (zh) * 2019-04-03 2019-05-28 广州康泽医疗科技有限公司 一种培养嗜黏蛋白阿克曼氏菌的培养基及其使用方法
CN110079474B (zh) * 2019-04-12 2022-11-25 沈阳药科大学 一种高密度培养艾克曼嗜黏蛋白菌的方法
TWI719549B (zh) * 2019-07-22 2021-02-21 大江生醫股份有限公司 促進嗜黏蛋白艾克曼菌生長之益生質組合物
CN110960558A (zh) * 2019-12-25 2020-04-07 西南大学 一种与代谢疾病相关的Akk菌动物用胶囊的制备方法
CN111304133B (zh) * 2020-03-20 2023-01-13 苏州普瑞森生物科技有限公司 一种培养嗜黏蛋白阿克曼氏菌的培养基及其使用方法和应用
CN111763653B (zh) * 2020-07-16 2023-02-10 君维安(武汉)生命科技有限公司 基于新型电子受体的嗜黏蛋白阿克曼氏菌的培养方法
CA3132176C (en) * 2020-11-11 2023-03-14 Enterobiome Inc. Medium supplement for high-yield industrial culture of fastidious anaerobes and medium composition containing the same
KR102222953B1 (ko) * 2020-11-11 2021-03-04 주식회사 엔테로바이옴 난배양성 혐기성 미생물의 고수율 배양을 위한 배지 보충제 및 그를 포함하는 배지 조성물
TW202332763A (zh) * 2021-12-01 2023-08-16 美商聯邦生物公司 微生物菌群
KR102643788B1 (ko) * 2021-12-08 2024-03-07 (주)헬스바이옴 아커만시아속 미생물의 고수율 생산용 배지 조성물, 그를 이용한 배양방법 및 동결건조 방법
CN114350571B (zh) * 2022-02-09 2024-04-19 广州知易生物科技有限公司 非动物源性培养基及用其培养嗜黏蛋白阿克曼氏菌的方法
CN114540246A (zh) * 2022-03-17 2022-05-27 中国科学院亚热带农业生态研究所 一种akk菌的选择培养基及分离鉴定方法
CN115287233A (zh) * 2022-08-10 2022-11-04 暨南大学附属第一医院（广州华侨医院） 一种阿克曼菌的复合培养基及其制备的粉剂和应用
CN115975885B (zh) * 2022-12-23 2024-07-16 中国农业大学 一种利用鱼加工副产物为氮源的嗜黏蛋白阿克曼菌培养基的制备

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JP2844484B2 (ja) * 1990-02-22 1999-01-06 味の素株式会社 組換え蛋白質の生産方法
WO1998054296A1 (en) 1997-05-28 1998-12-03 Chiron S.P.A. Culture medium with yeast or soy bean extract as aminoacid source and no protein complexes of animal origin
US6558926B1 (en) 1999-07-16 2003-05-06 Massachusetts Institute Of Technology Method for production of tetanus toxin using media substantially free of animal products
US20040265948A1 (en) * 2003-06-27 2004-12-30 White Michael Jon Microbial method for hydrolysis and oxidation of androst-5-ene and pregn-5-ene steroid esters
US7148041B2 (en) * 2003-09-25 2006-12-12 Allergan, Inc. Animal product free media and processes for obtaining a botulinum toxin
JP2006238706A (ja) * 2005-02-28 2006-09-14 Kanehide Bio Kk ビフィズス菌の培地、この培地を用いたビフィズス菌の培養方法、及びこの培養方法により培養したビフィズス菌を添加した食品
JP5704218B2 (ja) 2012-11-14 2015-04-22 ダイキン工業株式会社 ドライエッチングガスの製造方法
WO2014075745A1 (en) 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders

Also Published As

Publication number Publication date
HK1252413A1 (zh) 2019-05-24
JP2021100425A (ja) 2021-07-08
WO2016177801A1 (en) 2016-11-10
US20180094233A1 (en) 2018-04-05
EA201700497A1 (ru) 2018-05-31
CA2984986C (en) 2023-05-23
DK3292134T3 (da) 2020-11-23
KR102615649B1 (ko) 2023-12-19
US20210188923A1 (en) 2021-06-24
AU2016258976A1 (en) 2017-11-23
PT3292135T (pt) 2022-11-15
KR20240001261A (ko) 2024-01-03
CN107849093A (zh) 2018-03-27
EP3292134A1 (en) 2018-03-14
CA2984986A1 (en) 2016-11-10
MX2017014089A (es) 2018-08-15
EP3292134B1 (en) 2020-10-21
IL255406A0 (en) 2017-12-31
CN107849093B (zh) 2022-02-18
KR20180018524A (ko) 2018-02-21
JP6925280B2 (ja) 2021-08-25
IL255406B (en) 2021-09-30
JP2018515090A (ja) 2018-06-14
EP3783010A1 (en) 2021-02-24
US10988509B2 (en) 2021-04-27
AU2016258976B2 (en) 2021-02-25

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Legal Events

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]