EA201700497A1 - Способ культивирования бактерий - Google Patents

Способ культивирования бактерий

Info

Publication number
EA201700497A1
EA201700497A1 EA201700497A EA201700497A EA201700497A1 EA 201700497 A1 EA201700497 A1 EA 201700497A1 EA 201700497 A EA201700497 A EA 201700497A EA 201700497 A EA201700497 A EA 201700497A EA 201700497 A1 EA201700497 A1 EA 201700497A1
Authority
EA
Eurasian Patent Office
Prior art keywords
bacteria
muciniphila
allows
cultivating
cultivating bacteria
Prior art date
Application number
EA201700497A
Other languages
English (en)
Inventor
Клара Белзер
Виллем Де Вос
Original Assignee
Вагенинген Университет
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вагенинген Университет filed Critical Вагенинген Университет
Publication of EA201700497A1 publication Critical patent/EA201700497A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

В заявке описан рентабельный и эффективный способ культивирования бактерий Akkermansia muciniphila. Возможно получение высокого выхода биомассы в средах с заданным химическим составом. Это позволяет в промышленном масштабе получать бактерии A. muciniphila, применимые для человека, например, для использования в фармацевтической или пищевой промышленности. Бактерии A. muciniphila могут быть получены без использования продуктов животного происхождения, что позволяет применять их в широком диапазоне.
EA201700497A 2015-05-06 2016-05-04 Способ культивирования бактерий EA201700497A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15166598 2015-05-06
PCT/EP2016/060039 WO2016177801A1 (en) 2015-05-06 2016-05-04 Method of culturing akkermansia

Publications (1)

Publication Number Publication Date
EA201700497A1 true EA201700497A1 (ru) 2018-05-31

Family

ID=53059006

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201700497A EA201700497A1 (ru) 2015-05-06 2016-05-04 Способ культивирования бактерий

Country Status (15)

Country Link
US (2) US10988509B2 (ru)
EP (2) EP3783010A1 (ru)
JP (2) JP6925280B2 (ru)
KR (2) KR20240001261A (ru)
CN (1) CN107849093B (ru)
AU (1) AU2016258976B2 (ru)
BR (1) BR112017023756A2 (ru)
CA (1) CA2984986C (ru)
DK (1) DK3292134T3 (ru)
EA (1) EA201700497A1 (ru)
HK (1) HK1252413A1 (ru)
IL (1) IL255406B (ru)
MX (1) MX2017014089A (ru)
PT (1) PT3292135T (ru)
WO (1) WO2016177801A1 (ru)

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EP3881680A1 (en) 2014-10-31 2021-09-22 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
EA201800564A1 (ru) * 2016-04-11 2019-06-28 Вагенинген Университет Штамм akkermansia glycaniphilus, композиция, содержащая штамм, применение штамма и композиции, способ повышения уровня штамма akkermansia glycaniphilus в желудочно-кишечном тракте
CN107384828B (zh) * 2017-08-22 2020-06-16 中国农业科学院农产品加工研究所 阿克曼氏粘细菌培养基及其制备方法
CA3073838A1 (en) 2017-08-30 2019-03-07 Pendulum Therapeutics, Inc. Methods and compositions for treatment of microbiome-associated disorders
JP6967404B2 (ja) * 2017-08-31 2021-11-17 雪印メグミルク株式会社 アッカーマンシア・ムシニフィラ増加促進用組成物
JP6993142B2 (ja) * 2017-08-31 2022-01-13 雪印メグミルク株式会社 アッカーマンシア・ムシニフィラ増加促進用組成物
CN107903310B (zh) * 2017-11-16 2021-02-05 广州佰斯伦生物技术有限公司 一种重组膜蛋白、微生物、含有其的组合物及应用
KR102197180B1 (ko) * 2018-10-11 2020-12-31 주식회사 고바이오랩 아커만시아 뮤시니필라 균주 및 이를 포함하는 식욕 억제 및 대사성 질환 예방, 개선, 완화 및 치료용 조성물
CN109355349B (zh) * 2018-11-30 2021-03-26 江南大学 一种阿克曼氏菌特异性筛选培养基及其制备方法和应用
CN109810931A (zh) * 2019-04-03 2019-05-28 广州康泽医疗科技有限公司 一种培养嗜黏蛋白阿克曼氏菌的培养基及其使用方法
CN110079474B (zh) * 2019-04-12 2022-11-25 沈阳药科大学 一种高密度培养艾克曼嗜黏蛋白菌的方法
TWI719549B (zh) * 2019-07-22 2021-02-21 大江生醫股份有限公司 促進嗜黏蛋白艾克曼菌生長之益生質組合物
CN110960558A (zh) * 2019-12-25 2020-04-07 西南大学 一种与代谢疾病相关的Akk菌动物用胶囊的制备方法
CN111304133B (zh) * 2020-03-20 2023-01-13 苏州普瑞森生物科技有限公司 一种培养嗜黏蛋白阿克曼氏菌的培养基及其使用方法和应用
CN111763653B (zh) * 2020-07-16 2023-02-10 君维安(武汉)生命科技有限公司 基于新型电子受体的嗜黏蛋白阿克曼氏菌的培养方法
KR102222953B1 (ko) 2020-11-11 2021-03-04 주식회사 엔테로바이옴 난배양성 혐기성 미생물의 고수율 배양을 위한 배지 보충제 및 그를 포함하는 배지 조성물
CA3132176C (en) * 2020-11-11 2023-03-14 Enterobiome Inc. Medium supplement for high-yield industrial culture of fastidious anaerobes and medium composition containing the same
AU2022401992A1 (en) * 2021-12-01 2024-06-13 Kanvas Biosciences, Inc. Microbial consortia
KR102643788B1 (ko) * 2021-12-08 2024-03-07 (주)헬스바이옴 아커만시아속 미생물의 고수율 생산용 배지 조성물, 그를 이용한 배양방법 및 동결건조 방법
CN114350571B (zh) * 2022-02-09 2024-04-19 广州知易生物科技有限公司 非动物源性培养基及用其培养嗜黏蛋白阿克曼氏菌的方法
CN114540246A (zh) * 2022-03-17 2022-05-27 中国科学院亚热带农业生态研究所 一种akk菌的选择培养基及分离鉴定方法
CN115287233A (zh) * 2022-08-10 2022-11-04 暨南大学附属第一医院（广州华侨医院） 一种阿克曼菌的复合培养基及其制备的粉剂和应用
CN115975885B (zh) * 2022-12-23 2024-07-16 中国农业大学 一种利用鱼加工副产物为氮源的嗜黏蛋白阿克曼菌培养基的制备

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JP2844484B2 (ja) * 1990-02-22 1999-01-06 味の素株式会社 組換え蛋白質の生産方法
PT1849860E (pt) 1997-05-28 2011-02-23 Novartis Vaccines & Diagnostic Processo de preparação de um factor imunogénico de corynebacterium diphtheriae utilizando um meio de cultura com extracto de levedura como fonte de aminoácidos e sem complexos proteicos de origem animal
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US20040265948A1 (en) * 2003-06-27 2004-12-30 White Michael Jon Microbial method for hydrolysis and oxidation of androst-5-ene and pregn-5-ene steroid esters
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JP2006238706A (ja) * 2005-02-28 2006-09-14 Kanehide Bio Kk ビフィズス菌の培地、この培地を用いたビフィズス菌の培養方法、及びこの培養方法により培養したビフィズス菌を添加した食品
KR102000371B1 (ko) 2012-11-14 2019-07-15 다이킨 고교 가부시키가이샤 드라이 에칭 가스의 제조 방법
WO2014075745A1 (en) 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders

Also Published As

Publication number Publication date
AU2016258976A1 (en) 2017-11-23
EP3292134B1 (en) 2020-10-21
IL255406B (en) 2021-09-30
US20210188923A1 (en) 2021-06-24
CN107849093A (zh) 2018-03-27
PT3292135T (pt) 2022-11-15
US20180094233A1 (en) 2018-04-05
CA2984986A1 (en) 2016-11-10
WO2016177801A1 (en) 2016-11-10
KR20240001261A (ko) 2024-01-03
CA2984986C (en) 2023-05-23
US10988509B2 (en) 2021-04-27
JP2021100425A (ja) 2021-07-08
MX2017014089A (es) 2018-08-15
AU2016258976B2 (en) 2021-02-25
DK3292134T3 (da) 2020-11-23
JP2018515090A (ja) 2018-06-14
IL255406A0 (en) 2017-12-31
EP3292134A1 (en) 2018-03-14
CN107849093B (zh) 2022-02-18
KR20180018524A (ko) 2018-02-21
JP6925280B2 (ja) 2021-08-25
KR102615649B1 (ko) 2023-12-19
HK1252413A1 (zh) 2019-05-24
EP3783010A1 (en) 2021-02-24
BR112017023756A2 (pt) 2018-07-31

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