BR112016013461A2 - microrganismo corineforme com uma capacidade melhorada para produzir l-lisina, e método para produzir l-lisina - Google Patents
microrganismo corineforme com uma capacidade melhorada para produzir l-lisina, e método para produzir l-lisinaInfo
- Publication number
- BR112016013461A2 BR112016013461A2 BR112016013461-3A BR112016013461A BR112016013461A2 BR 112016013461 A2 BR112016013461 A2 BR 112016013461A2 BR 112016013461 A BR112016013461 A BR 112016013461A BR 112016013461 A2 BR112016013461 A2 BR 112016013461A2
- Authority
- BR
- Brazil
- Prior art keywords
- lysine
- microorganism
- producing
- produce
- corineform
- Prior art date
Links
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title abstract 4
- 244000005700 microbiome Species 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 241000186216 Corynebacterium Species 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
um microrganismo do género corynebacterium com uma capacidade melhorada de produzir l-lisina nos quais a proteína iniciadora da formação do septo é inativada, e um método para a produção de l-lisina usando o microrganismo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2013-0155634 | 2013-12-13 | ||
KR1020130155634A KR101565770B1 (ko) | 2013-12-13 | 2013-12-13 | L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신을 생산하는 방법 |
PCT/KR2014/011984 WO2015088204A1 (ko) | 2013-12-13 | 2014-12-08 | L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신을 생산하는 방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016013461A2 true BR112016013461A2 (pt) | 2018-01-16 |
BR112016013461B1 BR112016013461B1 (pt) | 2023-04-04 |
Family
ID=53371446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016013461-3A BR112016013461B1 (pt) | 2013-12-13 | 2014-12-08 | Microrganismo corineforme com uma capacidade melhorada para produzir l-lisina, e método para produzir l-lisina |
Country Status (10)
Country | Link |
---|---|
US (1) | US9777282B2 (pt) |
EP (1) | EP3078737B1 (pt) |
JP (1) | JP6263641B2 (pt) |
KR (1) | KR101565770B1 (pt) |
CN (1) | CN106062177B (pt) |
BR (1) | BR112016013461B1 (pt) |
MY (1) | MY179346A (pt) |
PL (1) | PL3078737T3 (pt) |
RU (1) | RU2651505C1 (pt) |
WO (1) | WO2015088204A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101740807B1 (ko) * | 2015-08-27 | 2017-05-26 | 씨제이제일제당 (주) | L-라이신 생산능을 가지는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신 생산방법 |
KR101766964B1 (ko) * | 2015-08-27 | 2017-08-09 | 씨제이제일제당 (주) | L-라이신 생산능을 가지는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신 생산방법 |
WO2019118548A1 (en) * | 2017-12-15 | 2019-06-20 | Archer Daniels Midland Company | Engineered strains of corynebacteria |
KR101915433B1 (ko) * | 2018-02-13 | 2018-11-05 | 씨제이제일제당 (주) | 시트레이트 신타아제 (Citrate synthase)의 활성이 약화된 변이형 폴리펩타이드 및 이를 이용한 L-아미노산 생산방법 |
KR102314884B1 (ko) * | 2021-04-12 | 2021-10-18 | 씨제이제일제당 (주) | 신규한 세포분해 막단백질 변이체 및 이를 이용한 l-라이신 생산 방법 |
KR102338875B1 (ko) * | 2021-04-12 | 2021-12-10 | 씨제이제일제당 (주) | 신규한 당 인산염 이성질화효소/에피머레이즈 변이체 및 이를 이용한 l-라이신 생산 방법 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR940001307B1 (ko) | 1991-12-27 | 1994-02-19 | 제일제당 주식회사 | L-라이신을 생산하는 신규 미생물 |
US6962989B1 (en) * | 1999-07-08 | 2005-11-08 | Basf Aktiengesellschaft | Corynebacterium glutamicum genes encoding novel proteins |
DE19953809A1 (de) | 1999-11-09 | 2001-05-10 | Degussa | Verfahren zur fermentativen Herstellung von L-Lysin unter Verwendung coryneformer Bakterien |
JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
AU2001287682A1 (en) * | 2000-09-12 | 2002-03-26 | Degussa A.G. | Nucleotide sequences coding for the ftsx gene |
JP2004261150A (ja) | 2003-03-04 | 2004-09-24 | Ajinomoto Co Inc | 目的物質の製造法 |
KR100789271B1 (ko) | 2005-11-30 | 2008-01-02 | 씨제이 주식회사 | L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 l-라이신을 생산하는 방법 |
CN101573438B (zh) | 2006-09-15 | 2013-01-02 | Cj第一制糖株式会社 | 具有增加的l-赖氨酸生产力的棒状杆菌和使用其生产l-赖氨酸的方法 |
WO2009116566A1 (ja) | 2008-03-18 | 2009-09-24 | 協和発酵キリン株式会社 | 工業的に有用な微生物 |
-
2013
- 2013-12-13 KR KR1020130155634A patent/KR101565770B1/ko active IP Right Grant
-
2014
- 2014-12-08 MY MYPI2016001049A patent/MY179346A/en unknown
- 2014-12-08 RU RU2016122017A patent/RU2651505C1/ru active
- 2014-12-08 EP EP14870476.0A patent/EP3078737B1/en active Active
- 2014-12-08 WO PCT/KR2014/011984 patent/WO2015088204A1/ko active Application Filing
- 2014-12-08 US US15/103,147 patent/US9777282B2/en active Active
- 2014-12-08 BR BR112016013461-3A patent/BR112016013461B1/pt active IP Right Grant
- 2014-12-08 JP JP2016557862A patent/JP6263641B2/ja active Active
- 2014-12-08 PL PL14870476T patent/PL3078737T3/pl unknown
- 2014-12-08 CN CN201480067603.1A patent/CN106062177B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
RU2651505C1 (ru) | 2018-04-19 |
KR101565770B1 (ko) | 2015-11-04 |
KR20150069340A (ko) | 2015-06-23 |
JP2017502688A (ja) | 2017-01-26 |
EP3078737A1 (en) | 2016-10-12 |
BR112016013461B1 (pt) | 2023-04-04 |
WO2015088204A1 (ko) | 2015-06-18 |
PL3078737T3 (pl) | 2019-10-31 |
CN106062177B (zh) | 2019-12-03 |
MY179346A (en) | 2020-11-04 |
CN106062177A (zh) | 2016-10-26 |
EP3078737B1 (en) | 2019-04-10 |
US9777282B2 (en) | 2017-10-03 |
EP3078737A4 (en) | 2017-06-28 |
JP6263641B2 (ja) | 2018-01-17 |
US20160355830A1 (en) | 2016-12-08 |
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/12/2014, OBSERVADAS AS CONDICOES LEGAIS |