BR112018006680A2 - supressor contendo nanomaterial conjugado por polímero solúvel em água e uso do mesmo - Google Patents
supressor contendo nanomaterial conjugado por polímero solúvel em água e uso do mesmoInfo
- Publication number
- BR112018006680A2 BR112018006680A2 BR112018006680-0A BR112018006680A BR112018006680A2 BR 112018006680 A2 BR112018006680 A2 BR 112018006680A2 BR 112018006680 A BR112018006680 A BR 112018006680A BR 112018006680 A2 BR112018006680 A2 BR 112018006680A2
- Authority
- BR
- Brazil
- Prior art keywords
- suppressor
- water soluble
- soluble polymer
- polymer conjugated
- nanomaterial
- Prior art date
Links
- 239000002086 nanomaterial Substances 0.000 title abstract 3
- 229920003169 water-soluble polymer Polymers 0.000 title abstract 3
- 239000000523 sample Substances 0.000 abstract 2
- 239000012620 biological material Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000013077 target material Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
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- C12Q1/701—Specific hybridization probes
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
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- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
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- G01N21/64—Fluorescence; Phosphorescence
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- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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Abstract
a presente invenção refere-se a um supressor contendo nanomaterial conjugado por polímero solúvel em água e a um uso do mesmo. o supressor contendo nanomaterial conjugado por polímero solúvel em água suprime efetivamente a fluorescência de uma sonda conjugada por material fluorescente. além disso, uma composição incluindo o supressor e uma sonda conjugada por material fluorescente pode detectar um material alvo existente em uma concentração baixa, e, logo, pode ser favoravelmente usado como uma composição ou kit para fornecer informações necessárias para a detecção de um biomaterial ou diagnóstico de uma doença.
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KR20150139174 | 2015-10-02 | ||
KR10-2015-0139174 | 2015-10-02 | ||
PCT/KR2016/006355 WO2017057823A1 (ko) | 2015-10-02 | 2016-06-15 | 수용성 고분자가 결합된 나노물질을 포함하는 소광제 및 이의 용도 |
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EP (1) | EP3358348A4 (pt) |
JP (1) | JP6704044B2 (pt) |
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CN (2) | CN108139391A (pt) |
AU (1) | AU2016329919B2 (pt) |
BR (1) | BR112018006680A2 (pt) |
CA (1) | CA3000631C (pt) |
DE (1) | DE202016009124U1 (pt) |
HK (1) | HK1253746A1 (pt) |
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MY (1) | MY183402A (pt) |
PH (1) | PH12018550037A1 (pt) |
SG (1) | SG11201802658VA (pt) |
WO (1) | WO2017057823A1 (pt) |
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KR102119010B1 (ko) | 2017-06-15 | 2020-06-04 | 건국대학교 산학협력단 | 펩티드 핵산 및 폴리에틸렌 글리콜 접합된 산화 그래핀을 포함하는 표적 유전자 발현 억제용 조성물 |
CN107796938B (zh) * | 2017-10-17 | 2020-03-27 | 中国农业科学院农业质量标准与检测技术研究所 | 一种核酸适配体荧光试纸条及其制备方法和应用 |
CN110237252A (zh) * | 2018-03-08 | 2019-09-17 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种核壳型多功能复合纳米材料及其制备方法与应用 |
CN109400887B (zh) * | 2018-10-17 | 2021-03-16 | 江西中洪博元生物技术有限公司 | 一种双荧光标记纳米材料的制备方法 |
JP2020076673A (ja) * | 2018-11-08 | 2020-05-21 | 国立大学法人埼玉大学 | 蛍光プローブ及びそのプローブを用いた迅速蛍光測定方法 |
CN109913504B (zh) * | 2019-04-23 | 2021-05-28 | 集美大学 | 一种利用改性琼脂制备生物乙醇的方法 |
CN110501494B (zh) * | 2019-07-16 | 2020-10-09 | 中国农业大学 | 一种基于二氧化锰纳米花和荧光材料的微生物检测方法 |
KR102533992B1 (ko) * | 2019-09-10 | 2023-05-19 | 서울대학교산학협력단 | 세포에의 외래 유전자 도입 확인 방법 및 외래 유전자 도입 세포의 제조 방법 |
KR102239459B1 (ko) * | 2019-09-16 | 2021-04-12 | 한국화학연구원 | 산화 그래핀, DNAzyme 및 PNA를 포함하는 온도 센서용 조성물 및 이를 이용한 온도 센싱 방법 |
KR102376443B1 (ko) * | 2020-02-26 | 2022-03-17 | 포항공과대학교 산학협력단 | 나노구조체, 나노구조체를 포함하는 바이오센서, 및 스크리닝 방법 |
KR20230115347A (ko) * | 2020-12-30 | 2023-08-02 | 호크아이 바이오 리미티드 | 바이오마커 검출을 위한 순수 그래핀 기반 바이오센서및 관련 코어 입자, 재료 구성 방법 및 시스템 |
EP4319727A1 (en) * | 2021-04-08 | 2024-02-14 | Georgia State University Research Foundation Inc. | Graphene oxide nanoparticles and methods of use for stimulating immune responses |
WO2023039362A1 (en) * | 2021-09-08 | 2023-03-16 | Lions VisionGift | Preserving fluorophore function |
WO2023089506A1 (en) * | 2021-11-17 | 2023-05-25 | Biorchestra Co., Ltd. | Amplification-free methods for measuring mirna |
WO2024010609A1 (en) * | 2022-07-06 | 2024-01-11 | Hawkeye Bio, Limited | Pristine graphene based biosensor for biomarker detection and related core particles, materials compositions methods and systems |
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KR101554173B1 (ko) | 2010-06-25 | 2015-09-18 | 한국과학기술원 | 형광분석기반 효소 활성 검출 방법 |
KR101818177B1 (ko) * | 2011-08-10 | 2018-01-12 | 한국과학기술원 | Dna 절단효소 또는 메틸전이효소 활성 분석용 그라핀 산화물 기반 키트 |
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US10351904B2 (en) * | 2012-04-24 | 2019-07-16 | Snu R&Db Foundation | Composition for detecting nucleic acid and method for detecting nucleic acid using same |
KR20140014443A (ko) * | 2012-07-24 | 2014-02-06 | 국립암센터 | 이황화물 연결자 함유 그래핀 옥사이드-광감각제 결합체 및 이를 이용한 암의 진단 및 치료용 조성물 |
WO2014055117A1 (en) * | 2012-10-04 | 2014-04-10 | Asuragen, Inc. | Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions |
KR101419254B1 (ko) | 2012-10-15 | 2014-07-17 | 국립암센터 | 효소 반응성 그라핀 옥사이드/생체 고분자-광감각제 나노복합체 및 이를 포함하는 형광 영상 진단 또는 광역학/광열 치료용 조성물 |
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KR102250362B1 (ko) | 2014-07-08 | 2021-05-12 | 세메스 주식회사 | 예비 토출 유닛, 이를 가지는 기판 처리 장치 및 방법 |
CN104634963A (zh) * | 2015-01-29 | 2015-05-20 | 江苏大学 | 一种基于聚乙二醇修饰的传感器及其检测凝血酶的方法 |
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- 2016-06-15 EP EP16851971.8A patent/EP3358348A4/en not_active Ceased
- 2016-06-15 DE DE202016009124.8U patent/DE202016009124U1/de active Active
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Also Published As
Publication number | Publication date |
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US10809196B2 (en) | 2020-10-20 |
US20180306718A1 (en) | 2018-10-25 |
JP2018533005A (ja) | 2018-11-08 |
MX2018004067A (es) | 2018-08-01 |
EP3358348A4 (en) | 2019-03-27 |
KR102109084B1 (ko) | 2020-05-11 |
DE202016009124U1 (de) | 2022-07-22 |
KR102109086B9 (ko) | 2022-12-08 |
HK1253746A1 (zh) | 2019-06-28 |
JP6704044B2 (ja) | 2020-06-03 |
KR102109086B1 (ko) | 2020-05-12 |
CA3000631A1 (en) | 2017-04-06 |
EP3358348A1 (en) | 2018-08-08 |
CN108139391A (zh) | 2018-06-08 |
CA3000631C (en) | 2023-07-04 |
PH12018550037A1 (en) | 2018-10-15 |
SG11201802658VA (en) | 2018-04-27 |
MY183402A (en) | 2021-02-18 |
KR102109084B9 (ko) | 2022-12-08 |
KR20190014566A (ko) | 2019-02-12 |
WO2017057823A1 (ko) | 2017-04-06 |
AU2016329919A1 (en) | 2018-05-10 |
KR20170040080A (ko) | 2017-04-12 |
CN116497156A (zh) | 2023-07-28 |
AU2016329919B2 (en) | 2023-05-18 |
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