BR112015023124A2 - liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal - Google Patents
liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinalInfo
- Publication number
- BR112015023124A2 BR112015023124A2 BR112015023124A BR112015023124A BR112015023124A2 BR 112015023124 A2 BR112015023124 A2 BR 112015023124A2 BR 112015023124 A BR112015023124 A BR 112015023124A BR 112015023124 A BR112015023124 A BR 112015023124A BR 112015023124 A2 BR112015023124 A2 BR 112015023124A2
- Authority
- BR
- Brazil
- Prior art keywords
- release
- therapeutic agents
- gastrointestinal tract
- targeted therapeutic
- probiotic organisms
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 210000001035 gastrointestinal tract Anatomy 0.000 title 1
- 239000006041 probiotic Substances 0.000 title 1
- 230000000529 probiotic effect Effects 0.000 title 1
- 235000018291 probiotics Nutrition 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361781810P | 2013-03-14 | 2013-03-14 | |
| US201361897378P | 2013-10-30 | 2013-10-30 | |
| PCT/US2014/027228 WO2014152338A1 (en) | 2013-03-14 | 2014-03-14 | Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015023124A2 true BR112015023124A2 (pt) | 2017-07-18 |
Family
ID=51581192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015023124A BR112015023124A2 (pt) | 2013-03-14 | 2014-03-14 | liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9907755B2 (enExample) |
| EP (1) | EP2968187A4 (enExample) |
| JP (2) | JP6464142B2 (enExample) |
| CN (2) | CN105120847B (enExample) |
| AU (3) | AU2014239883B2 (enExample) |
| BR (1) | BR112015023124A2 (enExample) |
| CA (3) | CA3013541C (enExample) |
| RU (1) | RU2015140610A (enExample) |
| WO (1) | WO2014152338A1 (enExample) |
Families Citing this family (150)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性t細胞の増殖または集積を誘導する作用を有する組成物 |
| KR20130098320A (ko) | 2010-08-04 | 2013-09-04 | 토마스 줄리어스 보로디 | 분변 세균총 이식을 위한 조성물, 그의 제조 방법과 사용 방법, 및 그를 전달하기 위한 장치 |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
| US11951140B2 (en) * | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
| US12257272B2 (en) | 2015-12-24 | 2025-03-25 | Seed Health, Inc. | Method and system for reducing the likelihood of developing depression in an individual |
| CN103561752B (zh) | 2011-03-09 | 2016-04-20 | 明尼苏达大学评议会 | 用于移植结肠微生物群的组合物和方法 |
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| CN104160014A (zh) | 2011-12-01 | 2014-11-19 | 国立大学法人东京大学 | 诱导调节性t细胞的增殖或积累的人源细菌 |
| CA2868362C (en) | 2012-03-29 | 2018-07-31 | Jerome Schentag | Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix |
| WO2013176774A1 (en) | 2012-05-25 | 2013-11-28 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| BR112015023124A2 (pt) | 2013-03-14 | 2017-07-18 | Therabiome Llc | liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| US12246043B2 (en) | 2013-12-20 | 2025-03-11 | Seed Health, Inc. | Topical application to treat acne vulgaris |
| US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
| US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
| US12329783B2 (en) | 2013-12-20 | 2025-06-17 | Seed Health, Inc. | Method and system to improve the health of a person's skin microbiome |
| US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
| US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
| ES2793530T3 (es) * | 2014-05-19 | 2020-11-16 | Tillotts Pharma Ag | Cápsulas revestidas de liberación modificada |
| EP2946773A1 (en) * | 2014-05-19 | 2015-11-25 | Tillotts Pharma AG | Modified release coated capsules |
| US10799541B2 (en) | 2014-07-01 | 2020-10-13 | Probi USA, Inc. | Bi-layer dual release probiotic tablets |
| WO2016065279A1 (en) * | 2014-10-23 | 2016-04-28 | Symbiotic Health Inc. | A capsule for the oral administration of biopharmaceuticals |
| EP4529950A3 (en) | 2014-10-31 | 2025-08-20 | Pendulum Therapeutics, Inc. | Methods and compositions relating to microbial treatment |
| MA41020A (fr) | 2014-11-25 | 2017-10-03 | Evelo Biosciences Inc | Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome |
| AU2018205072B2 (en) * | 2014-12-23 | 2020-05-21 | Cj Bioscience, Inc. | Immune modulation |
| KR102523805B1 (ko) | 2014-12-23 | 2023-04-20 | 4디 파마 리서치 리미티드 | 면역 조정 |
| KR20170091157A (ko) | 2014-12-23 | 2017-08-08 | 4디 파마 리서치 리미티드 | 피린 폴리펩티드 및 면역 조정 |
| WO2016183535A1 (en) | 2015-05-14 | 2016-11-17 | University Of Puerto Rico | Methods for restoring microbiota of newborns |
| KR102561989B1 (ko) | 2015-05-14 | 2023-07-31 | 핀치 테라퓨틱스 홀딩스 엘엘씨 | 대변 균무리 이식용 조성물, 및 이의 제조 및 사용 방법, 및 이의 전달을 위한 장치 |
| KR102358879B1 (ko) | 2015-05-22 | 2022-02-08 | 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 | 자폐 스펙트럼 장애 및 관련된 증상을 치료하는 방법 |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| JP6426264B2 (ja) | 2015-06-15 | 2018-11-21 | フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited | 細菌株を含む組成物 |
| PL3240554T3 (pl) | 2015-06-15 | 2020-02-28 | 4D Pharma Research Limited | Blautia stercosis i wexlerae do stosowania w leczeniu chorób zapalnych i autoimmunologicznych |
| RS59038B1 (sr) | 2015-06-15 | 2019-08-30 | 4D Pharma Res Ltd | Kompozicije koje sadrže bakterijske sojeve |
| CN106822007B (zh) | 2015-09-11 | 2021-12-31 | 西姆莱斯股份公司 | 口服制剂 |
| GB201519088D0 (en) | 2015-10-28 | 2015-12-09 | Metabogen Ab | The use of bacteria formulations |
| CA3005781C (en) | 2015-11-20 | 2019-01-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| ITUB20159138A1 (it) * | 2015-12-22 | 2017-06-22 | Euro Pharma Srl | Formulazioni terapeutiche integrative per la somministrazione separata, sequenziale o simultanea di acido butirrico, G.S.E probiotici e prebiotici. |
| WO2017117142A1 (en) | 2015-12-28 | 2017-07-06 | New York University | Device and method of restoring microbiota of newborns |
| EP3423093A4 (en) * | 2016-03-04 | 2019-11-13 | The Regents of The University of California | MICROBIAL CONSORTIUM AND USES THEREOF |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| HK1246670B (en) | 2016-03-04 | 2020-05-15 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
| US9855305B2 (en) | 2016-03-29 | 2018-01-02 | Companion Therapeutics Llc | Pharmaceutical composition containing combinations of vitamins, minerals, probiotics, and prebiotics effective in preventing adverse effects associated with the use of proton-pump inhibitors |
| KR102554351B1 (ko) | 2016-06-14 | 2023-07-13 | 베단타 바이오사이언시즈, 인크. | 클로스트리디움 디피실레 감염의 치료 |
| US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| JP7516007B2 (ja) * | 2016-06-28 | 2024-07-16 | セリバ・バイオロジクス・インコーポレイテッド | 経口抗生物質からのマイクロバイオーム防御 |
| US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
| TW201821093A (zh) | 2016-07-13 | 2018-06-16 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
| US20190247446A1 (en) * | 2016-07-19 | 2019-08-15 | Aobiome Llc | Ammonia oxidizing microorganisms for use and delivery to the gastrointestinal system |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
| US20180185421A1 (en) * | 2016-08-29 | 2018-07-05 | Tokyo Metropolitan Government | Composition comprising fecal microbiota |
| JP6862464B2 (ja) * | 2016-09-06 | 2021-04-21 | ビージーアイ シェンチェン | フィーカリバクテリウム・ロンガム(Faecalibacterium longum)およびその使用 |
| WO2018057747A1 (en) * | 2016-09-21 | 2018-03-29 | Finch Therapeutics, Inc. | Pharmaceutical compositions and methods for delivering microbial compositions |
| US10092601B2 (en) | 2016-10-11 | 2018-10-09 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| WO2018071536A1 (en) | 2016-10-11 | 2018-04-19 | Crestovo Holdings Llc | Compositions and methods for treating primary sclerosing cholangitis and related disorders |
| WO2018071537A1 (en) | 2016-10-11 | 2018-04-19 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| CN108066296B (zh) * | 2016-11-11 | 2020-11-17 | 南京益恒寿生命科技有限公司 | 一种生物学活性组分结肠靶向组合物及其应用 |
| KR102805966B1 (ko) * | 2016-12-01 | 2025-05-12 | 주식회사 포스코 | 바이오프린팅 기술을 이용한 셀룰로오스 나노섬유 전달체 및 이를 이용한 선택적 방출 방법 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| US10596206B1 (en) | 2017-03-14 | 2020-03-24 | Cornell University | Probiotic compositions and methods of use |
| EP3603421A4 (en) * | 2017-03-28 | 2021-02-17 | Ajinomoto Co., Inc. | DIET COMPOSITION TO IMPROVE THE INTRAINTESTINAL ENVIRONMENT |
| US11040073B2 (en) | 2017-04-05 | 2021-06-22 | Finch Therapeutics Holdings Llc | Compositions and methods for treating diverticulitis and related disorders |
| EP3606541A1 (en) | 2017-04-05 | 2020-02-12 | Crestovo Holdings LLC | Compositions and methods for treating parkinson's disease (pd) and related disorders |
| EP3630136B1 (en) | 2017-05-22 | 2021-04-21 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| MA41708A (fr) | 2017-05-24 | 2020-04-08 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| EP3630190B1 (en) | 2017-05-26 | 2024-02-21 | Finch Therapeutics Holdings LLC | Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same |
| EP3600363B1 (en) | 2017-06-14 | 2020-12-02 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| WO2018229188A1 (en) | 2017-06-14 | 2018-12-20 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| HUE052258T2 (hu) | 2017-06-14 | 2021-04-28 | 4D Pharma Res Ltd | Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása |
| WO2018230695A1 (ja) * | 2017-06-16 | 2018-12-20 | ビオフェルミン製薬株式会社 | 脂肪関連疾患及び/又は炎症の予防又は治療剤 |
| EP3641732A1 (en) * | 2017-06-21 | 2020-04-29 | Minerva Neurosciences, Inc. | Gastro-resistant controlled release oral dosage forms |
| CN107307429B (zh) * | 2017-07-04 | 2020-09-22 | 北京英茂药业有限公司 | 益生菌制剂的薄膜包衣预混剂及其制备方法、应用 |
| BR112019028301A2 (pt) * | 2017-07-05 | 2020-07-14 | Evelo Biosciences, Inc. | composições e métodos para tratar câncer com o uso de bifidobacterium animalis ssp. lactis |
| CA3072032A1 (en) | 2017-08-07 | 2019-02-14 | Finch Therapeutics, Inc. | Compositions and methods for maintaining and restoring a healthy gut barrier |
| US11241461B2 (en) | 2017-08-29 | 2022-02-08 | Evelo Biosciences, Inc. | Treating cancer using a blautia strain |
| WO2019046646A1 (en) * | 2017-08-30 | 2019-03-07 | Whole Biome Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS |
| CN111201032B (zh) * | 2017-10-09 | 2024-05-31 | 恩特罗姆公司 | 肿瘤相关抗原表位的小型生物群序列变体 |
| JP2021502964A (ja) | 2017-11-14 | 2021-02-04 | エヴェロ バイオサイエンシズ,インコーポレーテッド | ブラウティア(Blautia)株を使用して疾患を処置するための組成物及び方法 |
| WO2019099682A1 (en) | 2017-11-15 | 2019-05-23 | Evelo Biosciences, Inc. | Compositions and methods for treating immune disorders using immune modulating lactococcus bacteria strains |
| EP3485879A1 (en) * | 2017-11-17 | 2019-05-22 | Maat Pharma | Pharmaceutical oral formulation comrpsing bacteria |
| US10980482B2 (en) | 2017-12-06 | 2021-04-20 | James Phillip Jones | Sampling capsule system and methods |
| CN107998152A (zh) * | 2017-12-14 | 2018-05-08 | 乐普制药科技有限公司 | 一种结肠释放的益生菌片 |
| WO2019139943A1 (en) * | 2018-01-09 | 2019-07-18 | The Cleveland Clinic Foundation | Treatment and prevention of pathogenic bacterial overgrowth using butyrate-producing bacteria |
| KR102282490B1 (ko) | 2018-01-12 | 2021-07-28 | 주식회사 엠디헬스케어 | 패칼리박테리움 프라우스니찌 유래 나노소포 및 이의 용도 |
| WO2019152667A1 (en) | 2018-01-31 | 2019-08-08 | Evelo Biosciences, Inc. | Compositions and methods for treating immune disorders using lachnospiraceae bacteria |
| WO2019157066A1 (en) * | 2018-02-06 | 2019-08-15 | Robert Niichel | A multiparticulate including pharmaceutical or probiotic active ingredients |
| BR112020015639A2 (pt) | 2018-02-06 | 2021-03-30 | Evelo Biosciences, Inc. | Composições e métodos para o tratamento de câncer e distúrbios imunológicos usando bactérias veillonella |
| WO2019169143A1 (en) | 2018-02-28 | 2019-09-06 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer using turicibacter sanguinis |
| WO2019169168A1 (en) | 2018-02-28 | 2019-09-06 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer using agathobaculum |
| WO2019169160A1 (en) | 2018-02-28 | 2019-09-06 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer using ruminococcus gnavus |
| WO2019169138A1 (en) | 2018-02-28 | 2019-09-06 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer using paraclostridium benzoelyticum |
| WO2019178057A1 (en) | 2018-03-12 | 2019-09-19 | Evelo Biosciences, Inc. | Methods of treating cancer using burkholderia |
| WO2019178490A1 (en) | 2018-03-15 | 2019-09-19 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer and inflammation using klebsiella oxytoca |
| WO2019178487A2 (en) | 2018-03-15 | 2019-09-19 | Evelo Biosciences, Inc. | Compositions and methods for treating disease using klebsiella quasipneumoniae subsp. similipneumoniae |
| WO2019178494A1 (en) | 2018-03-15 | 2019-09-19 | Evelo Biosciences, Inc. | Compositions and methods for treating cancer and inflammation using tyzzerella nexilis |
| US10780135B2 (en) * | 2018-04-05 | 2020-09-22 | Hooman M. MELAMED | Probiotic formulation and method for weight loss treatment |
| EP3773645A4 (en) | 2018-04-10 | 2021-11-24 | Siolta Therapeutics, Inc. | MICROBIAL CONSORTIA |
| IT201800004764A1 (it) * | 2018-04-20 | 2019-10-20 | Composizione orale per uso come potenziatore di batteri eubiotici già presenti a livello intestinale. | |
| WO2019211419A1 (en) * | 2018-05-03 | 2019-11-07 | M.W. Encap Limited | Dosage forms for delivery of medicines to the lower gastrointestinal tract |
| EP3787624A4 (en) * | 2018-05-04 | 2022-03-30 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Capsule-in-capsule compositions of dabigatran etexilate |
| US20200000732A1 (en) * | 2018-05-30 | 2020-01-02 | DolCas Biotech, LLC | Probiotic compositions and dosage forms, and methods for preparing and using the same |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| US11166990B2 (en) | 2018-07-13 | 2021-11-09 | Finch Therapeutics Holdings Llc | Methods and compositions for treating ulcerative colitis |
| WO2020018949A2 (en) | 2018-07-19 | 2020-01-23 | Pendulum Therapeutics, Inc. | Methods and compositions for microbial engraftment |
| CN108567799A (zh) * | 2018-08-01 | 2018-09-25 | 中国人民解放军总医院 | 一种全粪菌复合胶囊及其制备方法和应用 |
| IL280779B2 (en) | 2018-08-17 | 2025-05-01 | Vedanta Biosciences Inc | Compositions for use in the treatment or prevention of Clostridium difficile infection |
| EP3870691A4 (en) | 2018-09-13 | 2022-09-07 | Xbiome Inc. | METHODS AND COMPOSITIONS FOR TREATING GASTROINTESTINAL AND INFLAMMATORY DISORDERS |
| US20210393737A1 (en) * | 2018-09-25 | 2021-12-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of mam polypeptides for the treatment of obesity and obesity-related disorders |
| KR20210065969A (ko) | 2018-09-27 | 2021-06-04 | 핀치 테라퓨틱스 홀딩스 엘엘씨 | 간질 및 관련 장애를 치료하기 위한 조성물 및 방법 |
| CN109999010B (zh) * | 2019-04-23 | 2021-06-15 | 河北地邦动物保健科技有限公司 | 一种益生菌包被微丸及其制备方法 |
| BR112021021429A2 (pt) * | 2019-04-30 | 2021-12-21 | Dsm Ip Assets Bv | Sistema de distribuição para vitaminas específicas solúveis em água |
| CN110368405A (zh) * | 2019-07-17 | 2019-10-25 | 上海交通大学医学院附属瑞金医院 | 一种肠道菌群的重建方法 |
| PE20221399A1 (es) | 2019-07-19 | 2022-09-15 | Finch Therapeutics Holdings Llc | Metodos y productos para el tratamiento de trastornos gastrointestinales |
| WO2021022110A1 (en) | 2019-08-01 | 2021-02-04 | Evelo Biosciences, Inc. | Inducing immune effects using bacteria of the genus bifidobacterium |
| BR112022002150A2 (pt) | 2019-08-05 | 2022-06-07 | Evelo Biosciences Inc | Composições e métodos para tratar psoríase e dermatite atópica com o uso de prevotella histicola |
| CA3148226A1 (en) | 2019-08-12 | 2021-02-18 | Massachusetts Institute Of Technology | Articles and methods for administration of therapeutic agents |
| EP4021467A4 (en) | 2019-08-28 | 2023-09-13 | Xbiome Inc. | COMPOSITIONS CONTAINING BACTERIAL SPECIES AND ASSOCIATED METHODS |
| JP2022547330A (ja) * | 2019-09-13 | 2022-11-11 | フィンチ セラピューティクス ホールディングス エルエルシー | 自閉症スペクトラム障害を治療するための組成物および方法 |
| WO2021071864A1 (en) | 2019-10-07 | 2021-04-15 | Siolta Therapeutics, Inc. | Therapeutic pharmaceutical compositions |
| AU2020370053A1 (en) | 2019-10-21 | 2022-04-21 | Soane Pharma LLC | Orally ingestible delivery system |
| KR20220128362A (ko) * | 2019-12-27 | 2022-09-20 | 에벨로 바이오사이언시즈, 인크. | 박테리아 및 미생물 세포외 소포체를 함유하는 고체 투여 형태 |
| TW202140050A (zh) | 2020-01-10 | 2021-11-01 | 美商艾弗洛生物科技股份有限公司 | 使用小韋榮氏球菌進行治療的組成物及方法 |
| KR102163637B1 (ko) * | 2020-04-06 | 2020-10-08 | 김한철 | 건강기능식품의 제조방법 |
| KR102167931B1 (ko) * | 2020-04-06 | 2020-10-20 | 김한철 | 건강기능식품의 제조방법 |
| KR102686373B1 (ko) * | 2020-04-28 | 2024-07-18 | 주식회사 모든바이오 | 양친매성 진세노사이드를 포함하는 미셀 입자, 이를 포함하는 조성물 및 이의 제조 방법 |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| WO2022061141A1 (en) | 2020-09-21 | 2022-03-24 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
| WO2022098961A1 (en) | 2020-11-06 | 2022-05-12 | Evelo Biosciences, Inc. | Inducing immune effects using veillonella parvula bacteria |
| CN112826836A (zh) * | 2021-01-08 | 2021-05-25 | 深圳未知君生物科技有限公司 | 一种粪菌口服制剂及其制备方法 |
| WO2022164422A1 (en) * | 2021-01-26 | 2022-08-04 | Seed Health Inc. | Methods and compositions for precision release of probiotics to improve human health |
| WO2022187064A1 (en) | 2021-03-01 | 2022-09-09 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
| WO2022216852A2 (en) * | 2021-04-07 | 2022-10-13 | Siolta Therapeutics, Inc. | Pharmaceutical compositions for treating diseases |
| US12011467B2 (en) | 2021-05-18 | 2024-06-18 | J. Craig Venter Institute, Inc. | Bacterial formulation |
| CA3223905A1 (en) * | 2021-06-24 | 2022-12-29 | Aouatef Bellamine | Method to control administration of active substance to the digestive tract |
| US20230226105A1 (en) * | 2021-11-10 | 2023-07-20 | Reverspah Llc | Methods and compositions for treating cancer |
| CN118524835A (zh) * | 2021-11-10 | 2024-08-20 | 瑞沃斯帕有限责任公司 | 用于治疗癌症的方法和组合物 |
| WO2023150376A1 (en) | 2022-02-07 | 2023-08-10 | Evelo Biosciences, Inc. | Compositions and methods of affecting cytokine levels using prevotella histicola |
| KR102464572B1 (ko) * | 2022-03-22 | 2022-11-10 | 대한켐텍 주식회사 | 프로바이오틱스 캡슐제 |
| WO2023183396A1 (en) | 2022-03-22 | 2023-09-28 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
| WO2023200837A1 (en) | 2022-04-13 | 2023-10-19 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
| CN115671067B (zh) * | 2022-10-25 | 2024-02-06 | 深圳万和制药有限公司 | 黄龙滴丸治疗和预防肠易激综合征的用途 |
| CN116270523B (zh) * | 2023-05-15 | 2023-08-08 | 四川厌氧生物科技有限责任公司 | 一种耐酸的口服双层胶囊及其制备方法 |
| WO2025063915A1 (en) * | 2023-09-21 | 2025-03-27 | Bi̇oprobi̇f Sağlik Gida Arge Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Production of probiotic bacteria based biomaterial and bioplastic |
Family Cites Families (133)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1576376A (en) | 1977-03-30 | 1980-10-08 | Benzon As Alfred | Multiple-unit drug dose |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4230687A (en) | 1978-05-30 | 1980-10-28 | Griffith Laboratories U.S.A., Inc. | Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices |
| ZA825384B (en) | 1981-07-31 | 1983-05-25 | Tillott J B Ltd | Orally administrable pharmaceutical compositions |
| JPS5911177A (ja) | 1982-07-12 | 1984-01-20 | Seikenkai | 新規乳酸桿菌 |
| DK151608C (da) | 1982-08-13 | 1988-06-20 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse |
| US4888176A (en) | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
| US4839281A (en) | 1985-04-17 | 1989-06-13 | New England Medical Center Hospitals, Inc. | Lactobacillus strains and methods of selection |
| US4789724A (en) | 1986-10-17 | 1988-12-06 | Massachusetts Institute Of Technology | Preparation of anhydride copolymers |
| US6024983A (en) | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
| US4857311A (en) | 1987-07-31 | 1989-08-15 | Massachusetts Institute Of Technology | Polyanhydrides with improved hydrolytic degradation properties |
| GB8812490D0 (en) | 1988-05-26 | 1988-06-29 | Agricultural & Food Res | Delayed release formulations |
| IT1227154B (it) | 1988-08-05 | 1991-03-19 | A Tosi Farmaceutici S R L Nova | Composizioni farmaceutiche per uso ginecologico a base di lattobacilli |
| AT391323B (de) | 1989-03-10 | 1990-09-25 | Jungbunzlauer Ag | Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure |
| GB8926639D0 (en) | 1989-11-24 | 1990-01-17 | Agricultural & Food Res | Delayed release formulations |
| US5178866A (en) | 1990-03-23 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug to the intestine |
| IT1246382B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
| IL98087A (en) | 1990-05-04 | 1996-11-14 | Perio Prod Ltd | Preparation for dispensing drugs in the colon |
| BR9106419A (pt) | 1990-05-04 | 1993-05-04 | Perio Prod Ltd | Sistema de liberacao colonica de medicamentos |
| GEP19971086B (en) | 1991-02-22 | 1997-12-02 | Tillotts Pharma Ag | Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine |
| US5622649A (en) | 1991-06-27 | 1997-04-22 | Emory University | Multiple emulsions and methods of preparation |
| DE69231313T2 (de) | 1991-11-22 | 2001-03-15 | Procter & Gamble Pharmaceuticals, Inc. | Risedronat enthaltende Arzneimittel mit verzögerter Wirkstoffabgabe |
| EP0728476B1 (en) | 1992-04-10 | 2002-09-04 | Hisamitsu Pharmaceutical Co., Inc. | Liposome composition |
| US5330759A (en) * | 1992-08-26 | 1994-07-19 | Sterling Winthrop Inc. | Enteric coated soft capsules and method of preparation thereof |
| JP2847326B2 (ja) | 1992-11-30 | 1999-01-20 | ファイザー・インク. | 支持された液体膜送達デバイス |
| US5413785A (en) | 1993-01-27 | 1995-05-09 | New England Deaconess Hospital Corp. | Methodology employing lactobacillus GG for reduction of plasma endotoxin levels circulating in-vivo |
| US5843479A (en) | 1993-02-26 | 1998-12-01 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
| US5686105A (en) | 1993-10-19 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
| PT621032E (pt) | 1993-04-23 | 2001-01-31 | Novartis Ag | Dispositivo de distribuicao de libertacao controlada de farmaco |
| US5733568A (en) | 1993-12-03 | 1998-03-31 | Lafor Laboratories Limited | Micro-encapsulated lactobacilli for medical applications |
| US5788687A (en) | 1994-02-01 | 1998-08-04 | Caphco, Inc | Compositions and devices for controlled release of active ingredients |
| ES2283503T3 (es) | 1994-04-22 | 2007-11-01 | Astellas Pharma Inc. | Sistema de liberacion de farmaco especifico de colon. |
| GB9412394D0 (en) | 1994-06-21 | 1994-08-10 | Danbiosyst Uk | Colonic drug delivery composition |
| US5599795A (en) | 1994-08-19 | 1997-02-04 | Mccann; Michael | Method for treatment of idiopathic inflammatory bowel disease (IIBD) |
| FI98343C (fi) | 1995-03-21 | 1997-06-10 | Orion Yhtymae Oy | Peroraalinen formulaatio |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| WO1997022353A1 (en) | 1995-12-21 | 1997-06-26 | Abbott Laboratories | Use of lactobacillus reuteri to inhibit cryptosporidiosis in mammals |
| AUPN881396A0 (en) | 1996-03-20 | 1996-04-18 | Arnott's Biscuits Limited | Enhancement of microbial colonization of the gastrointestinal tract |
| US6132710A (en) | 1997-03-17 | 2000-10-17 | Probiotix, Inc. | Preventing/treating neonatal NEC by administering lactobacillus salivarius and lactobacillus plantarum or a combination thereof |
| US6811786B1 (en) | 1999-04-01 | 2004-11-02 | Ganeden Biotech, Inc. | Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions |
| US6638534B1 (en) | 1998-07-28 | 2003-10-28 | Tanabe Seiyaku Co., Ltd. | Preparation capable of releasing drug at target site in intestine |
| PT1117386E (pt) | 1998-09-28 | 2005-04-29 | Warner Lambert Co | Administracao enterica e colonica utilizando capsulas de hpmc |
| ATE259829T1 (de) | 1998-10-20 | 2004-03-15 | Vlaams Interuniv Inst Biotech | Verwendung eines zytokine-produzierenden lactococcus stammes zur behandlung von kolitis |
| KR20010101171A (ko) | 1998-12-11 | 2001-11-14 | 추후기재 | 비뇨생식기 감염의 치료 및 예방을 위한 락토바실러스의경구 투여 |
| ID29150A (id) | 1999-01-15 | 2001-08-02 | Entpr Ireland Cs | Penggunaan lactobacillus salivarius |
| WO2000076478A1 (en) | 1999-06-14 | 2000-12-21 | Cosmo S.P.A. | Controlled release and taste masking oral pharmaceutical compositions |
| US6641808B1 (en) | 1999-09-22 | 2003-11-04 | Lacpro Industries, Llc | Composition for treatment of obesity |
| US6696057B1 (en) | 1999-09-22 | 2004-02-24 | Lacpro Industries, Inc. | Composition and method for treatment of gastrointestinal disorders and hyperlipidemia |
| US6849256B1 (en) | 1999-11-08 | 2005-02-01 | Ganeden Biotech Incorporated | Inhibition of pathogens by probiotic bacteria |
| CA2396237A1 (en) | 2000-01-07 | 2001-07-19 | Jacob Gabriel Michael | Selective activation of a th1 or th2 lymphocyte regulated immune response |
| FR2808689B1 (fr) | 2000-05-11 | 2004-09-03 | Agronomique Inst Nat Rech | Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs |
| US20040062757A1 (en) | 2001-06-05 | 2004-04-01 | Finegold Sydney M. | Method of testing gastrointestinal diseases associated with species of genus clostridium |
| GB0017673D0 (en) * | 2000-07-20 | 2000-09-06 | Mw Encap Limited | Delivery device |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| US20030092145A1 (en) | 2000-08-24 | 2003-05-15 | Vic Jira | Viral vaccine composition, process, and methods of use |
| PL205155B1 (pl) | 2001-02-19 | 2010-03-31 | Nestle Sa | Jadalny suchy produkt oraz sposób jego wytwarzania |
| KR100437497B1 (ko) | 2001-03-07 | 2004-06-25 | 주식회사 프로바이오닉 | 로타바이러스 및 유해 미생물 억제 활성을 가지는 신규내산성 락토바실러스 루테리 프로바이오-16 및 이를함유하는 생균활성제 |
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| US20030068356A1 (en) | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
| GB0127916D0 (en) | 2001-11-21 | 2002-01-16 | Rowett Res Inst | Method |
| US7101565B2 (en) | 2002-02-05 | 2006-09-05 | Corpak Medsystems, Inc. | Probiotic/prebiotic composition and delivery method |
| US8323692B2 (en) | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
| US20030194431A1 (en) | 2002-04-10 | 2003-10-16 | Miller Frederick H. | Multi-phase,multi-compartment capsular delivery apparatus and methods for using same |
| US7670612B2 (en) | 2002-04-10 | 2010-03-02 | Innercap Technologies, Inc. | Multi-phase, multi-compartment capsular delivery apparatus and methods for using same |
| DE60319822T2 (de) | 2002-06-19 | 2009-06-04 | Actogenix Nv | Verfahren und mittel zur erhöhung der darmabsorption |
| US8168170B2 (en) | 2002-10-03 | 2012-05-01 | The Procter And Gamble Company | Compositions having an inner core and at least three surrounding layers |
| US7670627B2 (en) | 2002-12-09 | 2010-03-02 | Salvona Ip Llc | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients |
| CN2601094Y (zh) | 2003-01-08 | 2004-01-28 | 江西本草天工科技有限责任公司 | 复合胶囊 |
| US20100221321A1 (en) | 2003-02-27 | 2010-09-02 | Innercap Technologies, Inc. | Apparatus And Methods For Delivering A Plurality Of Medicaments For Management Of Co-Morbid Diseases, Illnesses Or Conditions |
| US7718171B2 (en) | 2003-04-07 | 2010-05-18 | Chr. Hansen A/S | Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus |
| US8192733B2 (en) | 2003-08-29 | 2012-06-05 | Cobb & Associates | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
| US7749509B2 (en) | 2003-08-29 | 2010-07-06 | Cobb And Company, Llp | Treatment of autism using probiotic composition |
| US7731976B2 (en) | 2003-08-29 | 2010-06-08 | Cobb And Company, Llp | Treatment of irritable bowel syndrome using probiotic composition |
| US7759105B2 (en) | 2003-08-29 | 2010-07-20 | Cobb & Company, Llp | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
| US7645459B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
| DE102004026706A1 (de) | 2004-05-28 | 2005-12-15 | Merck Patent Gmbh | Orale Darreichungsform enthaltend probiotische Bakterien |
| CN100400036C (zh) | 2004-07-27 | 2008-07-09 | 北京华安佛医药研究中心有限公司 | 胃肠复合型胶囊及其制备方法和应用 |
| WO2006035418A2 (en) | 2004-09-27 | 2006-04-06 | Sigmoid Biotechnologies Limited | Microcapsules comprising a methylxanthine and a corticosteroid |
| US20060093592A1 (en) * | 2004-10-04 | 2006-05-04 | Nutracea | Synbiotics |
| US8092793B2 (en) | 2004-12-15 | 2012-01-10 | Qingdao East Sea Pharmaceuticals, Ltd. | Treating inflammatory bowel disease with live bacteria |
| US9149439B2 (en) | 2005-03-21 | 2015-10-06 | Sandoz Ag | Multi-particulate, modified-release composition |
| US7344867B2 (en) | 2005-04-15 | 2008-03-18 | Eamonn Connolly | Selection and use of lactic acid bacteria for reducing inflammation in mammals |
| HUP0500582A1 (hu) | 2005-06-13 | 2007-08-28 | Csaba Jozsef Dr Jaszberenyi | Szinergetikus élettani hatású élelmiszerek, élelmiszer-adalékok és táplálék-kiegészítõk vagy takarmányadalékok |
| ES2560240T5 (es) | 2005-07-29 | 2022-11-08 | Stichting Groningen Centre For Drug Res | Sistema de suministro pulsátil controlado por pH, métodos para la preparación y uso del mismo |
| JP5085547B2 (ja) | 2005-08-30 | 2012-11-28 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション | 生理活性ポリペプチドの細菌性送達 |
| US9265724B2 (en) * | 2005-11-07 | 2016-02-23 | Ram B. Murty | Oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery |
| AR054730A1 (es) | 2006-02-01 | 2007-07-11 | Allende Miguel Angel Garcia | Nuevas bacterias lacticas utiles como probioticos |
| CN101420850A (zh) | 2006-02-09 | 2009-04-29 | 阿尔巴医疗公司 | 紧密连接效应子的制剂 |
| BRPI0719319A2 (pt) * | 2006-11-17 | 2014-02-04 | Da Volterra | Liberação colônica usando contas de zn/pectina com um revestimento de eudragit |
| DE102006062250A1 (de) | 2006-12-22 | 2008-06-26 | Roland Saur-Brosch | Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden |
| US20080233184A1 (en) | 2007-03-19 | 2008-09-25 | Kenneth Looney | Combination enzyme products |
| EP2143424A4 (en) * | 2007-03-26 | 2013-07-31 | Teikoku Seiyaku Kk | ORAL PHARMACEUTICAL PREPARATION FOR SPECIFIC DELIVERY TO THE COLON |
| CN103120653B (zh) | 2007-04-04 | 2015-09-30 | 希格默伊德药业有限公司 | 一种口服药物组合物 |
| TW200904340A (en) | 2007-05-11 | 2009-02-01 | Mannatech Inc | Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same |
| DK1992351T3 (en) | 2007-05-18 | 2016-06-06 | Nestec Sa | Lactobacillus johnsonii for the prevention of post-surgical infection |
| EP1997499A1 (en) | 2007-05-31 | 2008-12-03 | Puleva Biotech, S.A. | Mammalian milk microorganisms, compositions containing them and their use for the treatment of mastitis |
| US9833510B2 (en) * | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
| US20090035370A1 (en) | 2007-08-02 | 2009-02-05 | Drugtech Corporation | Dosage form and method of use |
| EP2022502A1 (en) | 2007-08-10 | 2009-02-11 | Nestec S.A. | Lactobacillus rhamnosus and weight control |
| US9757346B2 (en) | 2008-09-03 | 2017-09-12 | Volant Holdings Gmbh | Compositions and methods for treating insulin resistance and non-insulin dependent diabetes mellitus (type II diabetes) |
| WO2010027498A2 (en) | 2008-09-03 | 2010-03-11 | New Science Holdings, Llc | Compositions and methods for inducing satiety and treating non-insulin dependent diabetes emillitus, pre-diabetic symptoms, insulin resistance and related disease states and conditions |
| WO2010054439A1 (en) | 2008-11-14 | 2010-05-20 | Unistraw Patent Holdings Limited | Probiotic compositions, methods and apparatus for their administration |
| EP2216034A1 (en) | 2009-02-10 | 2010-08-11 | Nestec S.A. | Lactobacillus helveticus CNCM I-4095 and weight control |
| US9474773B2 (en) | 2009-02-18 | 2016-10-25 | University Of Florida Research Foundation, Inc. | Lactobacillus supplement for alleviating type 1 diabetes |
| FR2942719B1 (fr) | 2009-03-04 | 2011-08-19 | Oreal | Utilisation de microorganismes probiotiques pour limiter les irritations cutanees |
| US8338162B2 (en) | 2009-04-17 | 2012-12-25 | Anaeropharma Science, Inc. | Obligately anaerobic mutant lactic acid bacterium and preparation method therefor, and expression vector functioning in obligately anaerobic lactic acid bacterium |
| US20120276149A1 (en) | 2009-10-15 | 2012-11-01 | Dan Littman | Methods for modulating bacterial infection |
| US8367418B2 (en) | 2009-10-23 | 2013-02-05 | Therasyn Sensors, Inc. | Method and system to provide personalized pharmaceutical compositions and dosages |
| US8999721B2 (en) | 2009-10-23 | 2015-04-07 | Therabrake, Inc. | Method and system to provide personalized pharmaceutical compositions and dosages |
| PT2538930T (pt) * | 2010-02-23 | 2016-08-05 | Da Volterra | Formulações para administração oral de adsorventes no intestino |
| US20130273154A1 (en) | 2011-03-02 | 2013-10-17 | Joseph M. Fayad | Oral formulations Mimetic of Roux-en-Y gastric bypass actions on the ileal brake; Compositions, Methods of Treatment, Diagnostics and Systems for treatment of metabolic syndrome manifestations including insulin resistance, fatty liver disease, hpperlipidemia, and type 2 diabetes |
| US9707207B2 (en) * | 2010-05-26 | 2017-07-18 | The United States Of America As Represented By The Department Of Veterans Affairs | Method for diagnosing, preventing, and treating neurological diseases |
| WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性t細胞の増殖または集積を誘導する作用を有する組成物 |
| EP2582387A2 (en) | 2010-06-17 | 2013-04-24 | The United States Of America As Represented By The Secretary, National Institutes Of Health | Compositions and methods for treating inflammatory conditions |
| EP2397145A1 (en) | 2010-06-18 | 2011-12-21 | Nestec S.A. | L. johnsonii La1, B. longum NCC2705 and immune disorders |
| CA2820178A1 (en) * | 2010-12-06 | 2012-06-14 | Degama Berrier Ltd. | Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof |
| RU2442572C1 (ru) | 2010-12-23 | 2012-02-20 | Ольга Львовна Титова | Энтеросолюбильная оболочка и композиция для ее получения |
| KR20190060879A (ko) | 2011-03-02 | 2019-06-03 | 제롬 쉔타그 | 단독으로 또는 c형 간염 바이러스 감염과 결합되는 간 지방증의 치료를 위한 조성물, 방법 및 진단 |
| GB2490671B (en) * | 2011-05-09 | 2017-12-20 | Mw Encap Ltd | Dosage Unit for Administration of Antibiotics to the Small and Large Intestine |
| CA2848757C (en) | 2011-09-14 | 2021-11-09 | University Of Guelph | Methods to culture human gastrointestinal microorganisms |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| CN104160014A (zh) | 2011-12-01 | 2014-11-19 | 国立大学法人东京大学 | 诱导调节性t细胞的增殖或积累的人源细菌 |
| CA2868362C (en) | 2012-03-29 | 2018-07-31 | Jerome Schentag | Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix |
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| EP2943213A4 (en) | 2013-01-08 | 2016-08-17 | Jerome Schentag | ACTIVATION OF THE ENDOGENOUS HORMONE PATHWAY OF ILLEAL BRAKE FOR THE REGENERATION OF AN ORGAN AND ASSOCIATED COMPOSITIONS, METHODS OF TREATMENT, DIAGNOSTICS, AND REGULATORY SYSTEMS |
| JP2016509003A (ja) | 2013-02-04 | 2016-03-24 | セレス セラピューティクス インコーポレイテッド | 組成物および方法 |
| WO2014121304A1 (en) | 2013-02-04 | 2014-08-07 | Seres Health, Inc. | Compositions and methods |
| WO2014153194A2 (en) | 2013-03-14 | 2014-09-25 | Seres Health, Inc. | Methods for pathogen detection and enrichment from materials and compositions |
| BR112015023124A2 (pt) | 2013-03-14 | 2017-07-18 | Therabiome Llc | liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal |
| AU2014232370B2 (en) | 2013-03-15 | 2018-11-01 | Société des Produits Nestlé S.A. | Network-based microbial compositions and methods |
| DK3074027T3 (da) | 2013-11-25 | 2025-03-17 | Nestle Sa | Synergistiske bakteriesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf |
| WO2015095241A2 (en) | 2013-12-16 | 2015-06-25 | Seres Health, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
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2014
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- 2014-03-14 AU AU2014239883A patent/AU2014239883B2/en active Active
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- 2014-03-14 CA CA3013541A patent/CA3013541C/en active Active
- 2014-03-14 CA CA3101218A patent/CA3101218A1/en not_active Abandoned
- 2014-03-14 CN CN201480014872.1A patent/CN105120847B/zh active Active
- 2014-03-14 CN CN201811473452.6A patent/CN110075130A/zh active Pending
- 2014-03-14 RU RU2015140610A patent/RU2015140610A/ru not_active Application Discontinuation
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| US10369111B2 (en) | 2019-08-06 |
| US20200138722A1 (en) | 2020-05-07 |
| JP6464142B2 (ja) | 2019-02-06 |
| NZ711298A (en) | 2021-07-30 |
| CA2904389C (en) | 2018-09-18 |
| CN105120847A (zh) | 2015-12-02 |
| US9907755B2 (en) | 2018-03-06 |
| AU2014239883A1 (en) | 2015-10-29 |
| US20160022592A1 (en) | 2016-01-28 |
| WO2014152338A1 (en) | 2014-09-25 |
| CA2904389A1 (en) | 2014-09-25 |
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| CN110075130A (zh) | 2019-08-02 |
| RU2015140610A (ru) | 2017-04-17 |
| US20180221286A1 (en) | 2018-08-09 |
| AU2020267253A1 (en) | 2020-12-10 |
| JP6860596B2 (ja) | 2021-04-14 |
| AU2018282453B2 (en) | 2020-08-13 |
| AU2014239883B2 (en) | 2019-01-17 |
| JP2019077705A (ja) | 2019-05-23 |
| EP2968187A1 (en) | 2016-01-20 |
| CN105120847B (zh) | 2018-12-28 |
| CA3101218A1 (en) | 2014-09-25 |
| HK1213805A1 (zh) | 2016-07-15 |
| AU2018282453A1 (en) | 2019-01-24 |
| US20230277468A1 (en) | 2023-09-07 |
| RU2015140610A3 (enExample) | 2018-03-19 |
| EP2968187A4 (en) | 2016-08-17 |
| CA3013541C (en) | 2021-01-19 |
| CA3013541A1 (en) | 2014-09-25 |
| US11590083B2 (en) | 2023-02-28 |
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