BR112015023124A2 - liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal - Google Patents

liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal

Info

Publication number
BR112015023124A2
BR112015023124A2 BR112015023124A BR112015023124A BR112015023124A2 BR 112015023124 A2 BR112015023124 A2 BR 112015023124A2 BR 112015023124 A BR112015023124 A BR 112015023124A BR 112015023124 A BR112015023124 A BR 112015023124A BR 112015023124 A2 BR112015023124 A2 BR 112015023124A2
Authority
BR
Brazil
Prior art keywords
release
therapeutic agents
gastrointestinal tract
targeted therapeutic
probiotic organisms
Prior art date
Application number
BR112015023124A
Other languages
English (en)
Portuguese (pt)
Inventor
Mohan Kabadi
Jerome J Schentag
Original Assignee
Therabiome Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therabiome Llc filed Critical Therabiome Llc
Publication of BR112015023124A2 publication Critical patent/BR112015023124A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112015023124A 2013-03-14 2014-03-14 liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal BR112015023124A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361781810P 2013-03-14 2013-03-14
US201361897378P 2013-10-30 2013-10-30
PCT/US2014/027228 WO2014152338A1 (en) 2013-03-14 2014-03-14 Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents

Publications (1)

Publication Number Publication Date
BR112015023124A2 true BR112015023124A2 (pt) 2017-07-18

Family

ID=51581192

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015023124A BR112015023124A2 (pt) 2013-03-14 2014-03-14 liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal

Country Status (9)

Country Link
US (4) US9907755B2 (enExample)
EP (1) EP2968187A4 (enExample)
JP (2) JP6464142B2 (enExample)
CN (2) CN105120847B (enExample)
AU (3) AU2014239883B2 (enExample)
BR (1) BR112015023124A2 (enExample)
CA (3) CA3013541C (enExample)
RU (1) RU2015140610A (enExample)
WO (1) WO2014152338A1 (enExample)

Families Citing this family (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
KR20130098320A (ko) 2010-08-04 2013-09-04 토마스 줄리어스 보로디 분변 세균총 이식을 위한 조성물, 그의 제조 방법과 사용 방법, 및 그를 전달하기 위한 장치
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US11951140B2 (en) * 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
CN103561752B (zh) 2011-03-09 2016-04-20 明尼苏达大学评议会 用于移植结肠微生物群的组合物和方法
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
CN104160014A (zh) 2011-12-01 2014-11-19 国立大学法人东京大学 诱导调节性t细胞的增殖或积累的人源细菌
CA2868362C (en) 2012-03-29 2018-07-31 Jerome Schentag Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
WO2013176774A1 (en) 2012-05-25 2013-11-28 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
BR112015023124A2 (pt) 2013-03-14 2017-07-18 Therabiome Llc liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
ES2793530T3 (es) * 2014-05-19 2020-11-16 Tillotts Pharma Ag Cápsulas revestidas de liberación modificada
EP2946773A1 (en) * 2014-05-19 2015-11-25 Tillotts Pharma AG Modified release coated capsules
US10799541B2 (en) 2014-07-01 2020-10-13 Probi USA, Inc. Bi-layer dual release probiotic tablets
WO2016065279A1 (en) * 2014-10-23 2016-04-28 Symbiotic Health Inc. A capsule for the oral administration of biopharmaceuticals
EP4529950A3 (en) 2014-10-31 2025-08-20 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
AU2018205072B2 (en) * 2014-12-23 2020-05-21 Cj Bioscience, Inc. Immune modulation
KR102523805B1 (ko) 2014-12-23 2023-04-20 4디 파마 리서치 리미티드 면역 조정
KR20170091157A (ko) 2014-12-23 2017-08-08 4디 파마 리서치 리미티드 피린 폴리펩티드 및 면역 조정
WO2016183535A1 (en) 2015-05-14 2016-11-17 University Of Puerto Rico Methods for restoring microbiota of newborns
KR102561989B1 (ko) 2015-05-14 2023-07-31 핀치 테라퓨틱스 홀딩스 엘엘씨 대변 균무리 이식용 조성물, 및 이의 제조 및 사용 방법, 및 이의 전달을 위한 장치
KR102358879B1 (ko) 2015-05-22 2022-02-08 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 자폐 스펙트럼 장애 및 관련된 증상을 치료하는 방법
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
JP6426264B2 (ja) 2015-06-15 2018-11-21 フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited 細菌株を含む組成物
PL3240554T3 (pl) 2015-06-15 2020-02-28 4D Pharma Research Limited Blautia stercosis i wexlerae do stosowania w leczeniu chorób zapalnych i autoimmunologicznych
RS59038B1 (sr) 2015-06-15 2019-08-30 4D Pharma Res Ltd Kompozicije koje sadrže bakterijske sojeve
CN106822007B (zh) 2015-09-11 2021-12-31 西姆莱斯股份公司 口服制剂
GB201519088D0 (en) 2015-10-28 2015-12-09 Metabogen Ab The use of bacteria formulations
CA3005781C (en) 2015-11-20 2019-01-22 4D Pharma Research Limited Compositions comprising bacterial strains
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
ITUB20159138A1 (it) * 2015-12-22 2017-06-22 Euro Pharma Srl Formulazioni terapeutiche integrative per la somministrazione separata, sequenziale o simultanea di acido butirrico, G.S.E probiotici e prebiotici.
WO2017117142A1 (en) 2015-12-28 2017-07-06 New York University Device and method of restoring microbiota of newborns
EP3423093A4 (en) * 2016-03-04 2019-11-13 The Regents of The University of California MICROBIAL CONSORTIUM AND USES THEREOF
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
HK1246670B (en) 2016-03-04 2020-05-15 4D Pharma Plc Compositions comprising bacterial blautia strains for treating visceral hypersensitivity
US9855305B2 (en) 2016-03-29 2018-01-02 Companion Therapeutics Llc Pharmaceutical composition containing combinations of vitamins, minerals, probiotics, and prebiotics effective in preventing adverse effects associated with the use of proton-pump inhibitors
KR102554351B1 (ko) 2016-06-14 2023-07-13 베단타 바이오사이언시즈, 인크. 클로스트리디움 디피실레 감염의 치료
US20170360848A1 (en) 2016-06-15 2017-12-21 Arizona Board Of Regents On Behalf Of Arizona State University Methods for treating autism spectrum disorder and associated symptoms
JP7516007B2 (ja) * 2016-06-28 2024-07-16 セリバ・バイオロジクス・インコーポレイテッド 経口抗生物質からのマイクロバイオーム防御
US10849936B2 (en) 2016-07-01 2020-12-01 Regents Of The University Of Minnesota Compositions and methods for C. difficile treatment
TW201821093A (zh) 2016-07-13 2018-06-16 英商4D製藥有限公司 包含細菌菌株之組合物
US20190247446A1 (en) * 2016-07-19 2019-08-15 Aobiome Llc Ammonia oxidizing microorganisms for use and delivery to the gastrointestinal system
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis
US20180185421A1 (en) * 2016-08-29 2018-07-05 Tokyo Metropolitan Government Composition comprising fecal microbiota
JP6862464B2 (ja) * 2016-09-06 2021-04-21 ビージーアイ シェンチェン フィーカリバクテリウム・ロンガム(Faecalibacterium longum)およびその使用
WO2018057747A1 (en) * 2016-09-21 2018-03-29 Finch Therapeutics, Inc. Pharmaceutical compositions and methods for delivering microbial compositions
US10092601B2 (en) 2016-10-11 2018-10-09 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
WO2018071536A1 (en) 2016-10-11 2018-04-19 Crestovo Holdings Llc Compositions and methods for treating primary sclerosing cholangitis and related disorders
WO2018071537A1 (en) 2016-10-11 2018-04-19 Crestovo Holdings Llc Compositions and methods for treating multiple sclerosis and related disorders
CN108066296B (zh) * 2016-11-11 2020-11-17 南京益恒寿生命科技有限公司 一种生物学活性组分结肠靶向组合物及其应用
KR102805966B1 (ko) * 2016-12-01 2025-05-12 주식회사 포스코 바이오프린팅 기술을 이용한 셀룰로오스 나노섬유 전달체 및 이를 이용한 선택적 방출 방법
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US10596206B1 (en) 2017-03-14 2020-03-24 Cornell University Probiotic compositions and methods of use
EP3603421A4 (en) * 2017-03-28 2021-02-17 Ajinomoto Co., Inc. DIET COMPOSITION TO IMPROVE THE INTRAINTESTINAL ENVIRONMENT
US11040073B2 (en) 2017-04-05 2021-06-22 Finch Therapeutics Holdings Llc Compositions and methods for treating diverticulitis and related disorders
EP3606541A1 (en) 2017-04-05 2020-02-12 Crestovo Holdings LLC Compositions and methods for treating parkinson's disease (pd) and related disorders
EP3630136B1 (en) 2017-05-22 2021-04-21 4D Pharma Research Limited Compositions comprising bacterial strains
MA41708A (fr) 2017-05-24 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3630190B1 (en) 2017-05-26 2024-02-21 Finch Therapeutics Holdings LLC Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same
EP3600363B1 (en) 2017-06-14 2020-12-02 4D Pharma Research Limited Compositions comprising bacterial strains
WO2018229188A1 (en) 2017-06-14 2018-12-20 4D Pharma Research Limited Compositions comprising bacterial strains
HUE052258T2 (hu) 2017-06-14 2021-04-28 4D Pharma Res Ltd Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása
WO2018230695A1 (ja) * 2017-06-16 2018-12-20 ビオフェルミン製薬株式会社 脂肪関連疾患及び/又は炎症の予防又は治療剤
EP3641732A1 (en) * 2017-06-21 2020-04-29 Minerva Neurosciences, Inc. Gastro-resistant controlled release oral dosage forms
CN107307429B (zh) * 2017-07-04 2020-09-22 北京英茂药业有限公司 益生菌制剂的薄膜包衣预混剂及其制备方法、应用
BR112019028301A2 (pt) * 2017-07-05 2020-07-14 Evelo Biosciences, Inc. composições e métodos para tratar câncer com o uso de bifidobacterium animalis ssp. lactis
CA3072032A1 (en) 2017-08-07 2019-02-14 Finch Therapeutics, Inc. Compositions and methods for maintaining and restoring a healthy gut barrier
US11241461B2 (en) 2017-08-29 2022-02-08 Evelo Biosciences, Inc. Treating cancer using a blautia strain
WO2019046646A1 (en) * 2017-08-30 2019-03-07 Whole Biome Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
CN111201032B (zh) * 2017-10-09 2024-05-31 恩特罗姆公司 肿瘤相关抗原表位的小型生物群序列变体
JP2021502964A (ja) 2017-11-14 2021-02-04 エヴェロ バイオサイエンシズ,インコーポレーテッド ブラウティア(Blautia)株を使用して疾患を処置するための組成物及び方法
WO2019099682A1 (en) 2017-11-15 2019-05-23 Evelo Biosciences, Inc. Compositions and methods for treating immune disorders using immune modulating lactococcus bacteria strains
EP3485879A1 (en) * 2017-11-17 2019-05-22 Maat Pharma Pharmaceutical oral formulation comrpsing bacteria
US10980482B2 (en) 2017-12-06 2021-04-20 James Phillip Jones Sampling capsule system and methods
CN107998152A (zh) * 2017-12-14 2018-05-08 乐普制药科技有限公司 一种结肠释放的益生菌片
WO2019139943A1 (en) * 2018-01-09 2019-07-18 The Cleveland Clinic Foundation Treatment and prevention of pathogenic bacterial overgrowth using butyrate-producing bacteria
KR102282490B1 (ko) 2018-01-12 2021-07-28 주식회사 엠디헬스케어 패칼리박테리움 프라우스니찌 유래 나노소포 및 이의 용도
WO2019152667A1 (en) 2018-01-31 2019-08-08 Evelo Biosciences, Inc. Compositions and methods for treating immune disorders using lachnospiraceae bacteria
WO2019157066A1 (en) * 2018-02-06 2019-08-15 Robert Niichel A multiparticulate including pharmaceutical or probiotic active ingredients
BR112020015639A2 (pt) 2018-02-06 2021-03-30 Evelo Biosciences, Inc. Composições e métodos para o tratamento de câncer e distúrbios imunológicos usando bactérias veillonella
WO2019169143A1 (en) 2018-02-28 2019-09-06 Evelo Biosciences, Inc. Compositions and methods for treating cancer using turicibacter sanguinis
WO2019169168A1 (en) 2018-02-28 2019-09-06 Evelo Biosciences, Inc. Compositions and methods for treating cancer using agathobaculum
WO2019169160A1 (en) 2018-02-28 2019-09-06 Evelo Biosciences, Inc. Compositions and methods for treating cancer using ruminococcus gnavus
WO2019169138A1 (en) 2018-02-28 2019-09-06 Evelo Biosciences, Inc. Compositions and methods for treating cancer using paraclostridium benzoelyticum
WO2019178057A1 (en) 2018-03-12 2019-09-19 Evelo Biosciences, Inc. Methods of treating cancer using burkholderia
WO2019178490A1 (en) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions and methods for treating cancer and inflammation using klebsiella oxytoca
WO2019178487A2 (en) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions and methods for treating disease using klebsiella quasipneumoniae subsp. similipneumoniae
WO2019178494A1 (en) 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions and methods for treating cancer and inflammation using tyzzerella nexilis
US10780135B2 (en) * 2018-04-05 2020-09-22 Hooman M. MELAMED Probiotic formulation and method for weight loss treatment
EP3773645A4 (en) 2018-04-10 2021-11-24 Siolta Therapeutics, Inc. MICROBIAL CONSORTIA
IT201800004764A1 (it) * 2018-04-20 2019-10-20 Composizione orale per uso come potenziatore di batteri eubiotici già presenti a livello intestinale.
WO2019211419A1 (en) * 2018-05-03 2019-11-07 M.W. Encap Limited Dosage forms for delivery of medicines to the lower gastrointestinal tract
EP3787624A4 (en) * 2018-05-04 2022-03-30 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Capsule-in-capsule compositions of dabigatran etexilate
US20200000732A1 (en) * 2018-05-30 2020-01-02 DolCas Biotech, LLC Probiotic compositions and dosage forms, and methods for preparing and using the same
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
US11166990B2 (en) 2018-07-13 2021-11-09 Finch Therapeutics Holdings Llc Methods and compositions for treating ulcerative colitis
WO2020018949A2 (en) 2018-07-19 2020-01-23 Pendulum Therapeutics, Inc. Methods and compositions for microbial engraftment
CN108567799A (zh) * 2018-08-01 2018-09-25 中国人民解放军总医院 一种全粪菌复合胶囊及其制备方法和应用
IL280779B2 (en) 2018-08-17 2025-05-01 Vedanta Biosciences Inc Compositions for use in the treatment or prevention of Clostridium difficile infection
EP3870691A4 (en) 2018-09-13 2022-09-07 Xbiome Inc. METHODS AND COMPOSITIONS FOR TREATING GASTROINTESTINAL AND INFLAMMATORY DISORDERS
US20210393737A1 (en) * 2018-09-25 2021-12-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of mam polypeptides for the treatment of obesity and obesity-related disorders
KR20210065969A (ko) 2018-09-27 2021-06-04 핀치 테라퓨틱스 홀딩스 엘엘씨 간질 및 관련 장애를 치료하기 위한 조성물 및 방법
CN109999010B (zh) * 2019-04-23 2021-06-15 河北地邦动物保健科技有限公司 一种益生菌包被微丸及其制备方法
BR112021021429A2 (pt) * 2019-04-30 2021-12-21 Dsm Ip Assets Bv Sistema de distribuição para vitaminas específicas solúveis em água
CN110368405A (zh) * 2019-07-17 2019-10-25 上海交通大学医学院附属瑞金医院 一种肠道菌群的重建方法
PE20221399A1 (es) 2019-07-19 2022-09-15 Finch Therapeutics Holdings Llc Metodos y productos para el tratamiento de trastornos gastrointestinales
WO2021022110A1 (en) 2019-08-01 2021-02-04 Evelo Biosciences, Inc. Inducing immune effects using bacteria of the genus bifidobacterium
BR112022002150A2 (pt) 2019-08-05 2022-06-07 Evelo Biosciences Inc Composições e métodos para tratar psoríase e dermatite atópica com o uso de prevotella histicola
CA3148226A1 (en) 2019-08-12 2021-02-18 Massachusetts Institute Of Technology Articles and methods for administration of therapeutic agents
EP4021467A4 (en) 2019-08-28 2023-09-13 Xbiome Inc. COMPOSITIONS CONTAINING BACTERIAL SPECIES AND ASSOCIATED METHODS
JP2022547330A (ja) * 2019-09-13 2022-11-11 フィンチ セラピューティクス ホールディングス エルエルシー 自閉症スペクトラム障害を治療するための組成物および方法
WO2021071864A1 (en) 2019-10-07 2021-04-15 Siolta Therapeutics, Inc. Therapeutic pharmaceutical compositions
AU2020370053A1 (en) 2019-10-21 2022-04-21 Soane Pharma LLC Orally ingestible delivery system
KR20220128362A (ko) * 2019-12-27 2022-09-20 에벨로 바이오사이언시즈, 인크. 박테리아 및 미생물 세포외 소포체를 함유하는 고체 투여 형태
TW202140050A (zh) 2020-01-10 2021-11-01 美商艾弗洛生物科技股份有限公司 使用小韋榮氏球菌進行治療的組成物及方法
KR102163637B1 (ko) * 2020-04-06 2020-10-08 김한철 건강기능식품의 제조방법
KR102167931B1 (ko) * 2020-04-06 2020-10-20 김한철 건강기능식품의 제조방법
KR102686373B1 (ko) * 2020-04-28 2024-07-18 주식회사 모든바이오 양친매성 진세노사이드를 포함하는 미셀 입자, 이를 포함하는 조성물 및 이의 제조 방법
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
WO2022061141A1 (en) 2020-09-21 2022-03-24 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola
WO2022098961A1 (en) 2020-11-06 2022-05-12 Evelo Biosciences, Inc. Inducing immune effects using veillonella parvula bacteria
CN112826836A (zh) * 2021-01-08 2021-05-25 深圳未知君生物科技有限公司 一种粪菌口服制剂及其制备方法
WO2022164422A1 (en) * 2021-01-26 2022-08-04 Seed Health Inc. Methods and compositions for precision release of probiotics to improve human health
WO2022187064A1 (en) 2021-03-01 2022-09-09 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola
WO2022216852A2 (en) * 2021-04-07 2022-10-13 Siolta Therapeutics, Inc. Pharmaceutical compositions for treating diseases
US12011467B2 (en) 2021-05-18 2024-06-18 J. Craig Venter Institute, Inc. Bacterial formulation
CA3223905A1 (en) * 2021-06-24 2022-12-29 Aouatef Bellamine Method to control administration of active substance to the digestive tract
US20230226105A1 (en) * 2021-11-10 2023-07-20 Reverspah Llc Methods and compositions for treating cancer
CN118524835A (zh) * 2021-11-10 2024-08-20 瑞沃斯帕有限责任公司 用于治疗癌症的方法和组合物
WO2023150376A1 (en) 2022-02-07 2023-08-10 Evelo Biosciences, Inc. Compositions and methods of affecting cytokine levels using prevotella histicola
KR102464572B1 (ko) * 2022-03-22 2022-11-10 대한켐텍 주식회사 프로바이오틱스 캡슐제
WO2023183396A1 (en) 2022-03-22 2023-09-28 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola
WO2023200837A1 (en) 2022-04-13 2023-10-19 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola
CN115671067B (zh) * 2022-10-25 2024-02-06 深圳万和制药有限公司 黄龙滴丸治疗和预防肠易激综合征的用途
CN116270523B (zh) * 2023-05-15 2023-08-08 四川厌氧生物科技有限责任公司 一种耐酸的口服双层胶囊及其制备方法
WO2025063915A1 (en) * 2023-09-21 2025-03-27 Bi̇oprobi̇f Sağlik Gida Arge Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ Production of probiotic bacteria based biomaterial and bioplastic

Family Cites Families (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576376A (en) 1977-03-30 1980-10-08 Benzon As Alfred Multiple-unit drug dose
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4230687A (en) 1978-05-30 1980-10-28 Griffith Laboratories U.S.A., Inc. Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices
ZA825384B (en) 1981-07-31 1983-05-25 Tillott J B Ltd Orally administrable pharmaceutical compositions
JPS5911177A (ja) 1982-07-12 1984-01-20 Seikenkai 新規乳酸桿菌
DK151608C (da) 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
US4888176A (en) 1984-05-21 1989-12-19 Massachusetts Institute Of Technology Controlled drug delivery high molecular weight polyanhydrides
US4839281A (en) 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
US4789724A (en) 1986-10-17 1988-12-06 Massachusetts Institute Of Technology Preparation of anhydride copolymers
US6024983A (en) 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US4857311A (en) 1987-07-31 1989-08-15 Massachusetts Institute Of Technology Polyanhydrides with improved hydrolytic degradation properties
GB8812490D0 (en) 1988-05-26 1988-06-29 Agricultural & Food Res Delayed release formulations
IT1227154B (it) 1988-08-05 1991-03-19 A Tosi Farmaceutici S R L Nova Composizioni farmaceutiche per uso ginecologico a base di lattobacilli
AT391323B (de) 1989-03-10 1990-09-25 Jungbunzlauer Ag Mikroorganismus der species bacillus coagulans sowie ein verfahren zur herstellung von optisch reiner l(+)-milchsaeure
GB8926639D0 (en) 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
US5178866A (en) 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
IT1246382B (it) 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
IL98087A (en) 1990-05-04 1996-11-14 Perio Prod Ltd Preparation for dispensing drugs in the colon
BR9106419A (pt) 1990-05-04 1993-05-04 Perio Prod Ltd Sistema de liberacao colonica de medicamentos
GEP19971086B (en) 1991-02-22 1997-12-02 Tillotts Pharma Ag Peroral Pharmaceutically Dispensed Form for Selective Introducing of the Medicine into the Intestine
US5622649A (en) 1991-06-27 1997-04-22 Emory University Multiple emulsions and methods of preparation
DE69231313T2 (de) 1991-11-22 2001-03-15 Procter & Gamble Pharmaceuticals, Inc. Risedronat enthaltende Arzneimittel mit verzögerter Wirkstoffabgabe
EP0728476B1 (en) 1992-04-10 2002-09-04 Hisamitsu Pharmaceutical Co., Inc. Liposome composition
US5330759A (en) * 1992-08-26 1994-07-19 Sterling Winthrop Inc. Enteric coated soft capsules and method of preparation thereof
JP2847326B2 (ja) 1992-11-30 1999-01-20 ファイザー・インク. 支持された液体膜送達デバイス
US5413785A (en) 1993-01-27 1995-05-09 New England Deaconess Hospital Corp. Methodology employing lactobacillus GG for reduction of plasma endotoxin levels circulating in-vivo
US5843479A (en) 1993-02-26 1998-12-01 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
PT621032E (pt) 1993-04-23 2001-01-31 Novartis Ag Dispositivo de distribuicao de libertacao controlada de farmaco
US5733568A (en) 1993-12-03 1998-03-31 Lafor Laboratories Limited Micro-encapsulated lactobacilli for medical applications
US5788687A (en) 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
ES2283503T3 (es) 1994-04-22 2007-11-01 Astellas Pharma Inc. Sistema de liberacion de farmaco especifico de colon.
GB9412394D0 (en) 1994-06-21 1994-08-10 Danbiosyst Uk Colonic drug delivery composition
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
FI98343C (fi) 1995-03-21 1997-06-10 Orion Yhtymae Oy Peroraalinen formulaatio
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
WO1997022353A1 (en) 1995-12-21 1997-06-26 Abbott Laboratories Use of lactobacillus reuteri to inhibit cryptosporidiosis in mammals
AUPN881396A0 (en) 1996-03-20 1996-04-18 Arnott's Biscuits Limited Enhancement of microbial colonization of the gastrointestinal tract
US6132710A (en) 1997-03-17 2000-10-17 Probiotix, Inc. Preventing/treating neonatal NEC by administering lactobacillus salivarius and lactobacillus plantarum or a combination thereof
US6811786B1 (en) 1999-04-01 2004-11-02 Ganeden Biotech, Inc. Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions
US6638534B1 (en) 1998-07-28 2003-10-28 Tanabe Seiyaku Co., Ltd. Preparation capable of releasing drug at target site in intestine
PT1117386E (pt) 1998-09-28 2005-04-29 Warner Lambert Co Administracao enterica e colonica utilizando capsulas de hpmc
ATE259829T1 (de) 1998-10-20 2004-03-15 Vlaams Interuniv Inst Biotech Verwendung eines zytokine-produzierenden lactococcus stammes zur behandlung von kolitis
KR20010101171A (ko) 1998-12-11 2001-11-14 추후기재 비뇨생식기 감염의 치료 및 예방을 위한 락토바실러스의경구 투여
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
WO2000076478A1 (en) 1999-06-14 2000-12-21 Cosmo S.P.A. Controlled release and taste masking oral pharmaceutical compositions
US6641808B1 (en) 1999-09-22 2003-11-04 Lacpro Industries, Llc Composition for treatment of obesity
US6696057B1 (en) 1999-09-22 2004-02-24 Lacpro Industries, Inc. Composition and method for treatment of gastrointestinal disorders and hyperlipidemia
US6849256B1 (en) 1999-11-08 2005-02-01 Ganeden Biotech Incorporated Inhibition of pathogens by probiotic bacteria
CA2396237A1 (en) 2000-01-07 2001-07-19 Jacob Gabriel Michael Selective activation of a th1 or th2 lymphocyte regulated immune response
FR2808689B1 (fr) 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
US20040062757A1 (en) 2001-06-05 2004-04-01 Finegold Sydney M. Method of testing gastrointestinal diseases associated with species of genus clostridium
GB0017673D0 (en) * 2000-07-20 2000-09-06 Mw Encap Limited Delivery device
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
US20030092145A1 (en) 2000-08-24 2003-05-15 Vic Jira Viral vaccine composition, process, and methods of use
PL205155B1 (pl) 2001-02-19 2010-03-31 Nestle Sa Jadalny suchy produkt oraz sposób jego wytwarzania
KR100437497B1 (ko) 2001-03-07 2004-06-25 주식회사 프로바이오닉 로타바이러스 및 유해 미생물 억제 활성을 가지는 신규내산성 락토바실러스 루테리 프로바이오-16 및 이를함유하는 생균활성제
US7780961B2 (en) 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
US20030068356A1 (en) 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
GB0127916D0 (en) 2001-11-21 2002-01-16 Rowett Res Inst Method
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
US8323692B2 (en) 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
US20030194431A1 (en) 2002-04-10 2003-10-16 Miller Frederick H. Multi-phase,multi-compartment capsular delivery apparatus and methods for using same
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
DE60319822T2 (de) 2002-06-19 2009-06-04 Actogenix Nv Verfahren und mittel zur erhöhung der darmabsorption
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
US7670627B2 (en) 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
CN2601094Y (zh) 2003-01-08 2004-01-28 江西本草天工科技有限责任公司 复合胶囊
US20100221321A1 (en) 2003-02-27 2010-09-02 Innercap Technologies, Inc. Apparatus And Methods For Delivering A Plurality Of Medicaments For Management Of Co-Morbid Diseases, Illnesses Or Conditions
US7718171B2 (en) 2003-04-07 2010-05-18 Chr. Hansen A/S Reducing heart rate in mammals using milk derived fermentation products produced using Lactobacillus helveticus
US8192733B2 (en) 2003-08-29 2012-06-05 Cobb & Associates Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US7749509B2 (en) 2003-08-29 2010-07-06 Cobb And Company, Llp Treatment of autism using probiotic composition
US7731976B2 (en) 2003-08-29 2010-06-08 Cobb And Company, Llp Treatment of irritable bowel syndrome using probiotic composition
US7759105B2 (en) 2003-08-29 2010-07-20 Cobb & Company, Llp Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US7645459B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
DE102004026706A1 (de) 2004-05-28 2005-12-15 Merck Patent Gmbh Orale Darreichungsform enthaltend probiotische Bakterien
CN100400036C (zh) 2004-07-27 2008-07-09 北京华安佛医药研究中心有限公司 胃肠复合型胶囊及其制备方法和应用
WO2006035418A2 (en) 2004-09-27 2006-04-06 Sigmoid Biotechnologies Limited Microcapsules comprising a methylxanthine and a corticosteroid
US20060093592A1 (en) * 2004-10-04 2006-05-04 Nutracea Synbiotics
US8092793B2 (en) 2004-12-15 2012-01-10 Qingdao East Sea Pharmaceuticals, Ltd. Treating inflammatory bowel disease with live bacteria
US9149439B2 (en) 2005-03-21 2015-10-06 Sandoz Ag Multi-particulate, modified-release composition
US7344867B2 (en) 2005-04-15 2008-03-18 Eamonn Connolly Selection and use of lactic acid bacteria for reducing inflammation in mammals
HUP0500582A1 (hu) 2005-06-13 2007-08-28 Csaba Jozsef Dr Jaszberenyi Szinergetikus élettani hatású élelmiszerek, élelmiszer-adalékok és táplálék-kiegészítõk vagy takarmányadalékok
ES2560240T5 (es) 2005-07-29 2022-11-08 Stichting Groningen Centre For Drug Res Sistema de suministro pulsátil controlado por pH, métodos para la preparación y uso del mismo
JP5085547B2 (ja) 2005-08-30 2012-11-28 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション 生理活性ポリペプチドの細菌性送達
US9265724B2 (en) * 2005-11-07 2016-02-23 Ram B. Murty Oral dosage form of tetrahydrocannabinol and a method of avoiding and/or suppressing hepatic first pass metabolism via targeted chylomicron/lipoprotein delivery
AR054730A1 (es) 2006-02-01 2007-07-11 Allende Miguel Angel Garcia Nuevas bacterias lacticas utiles como probioticos
CN101420850A (zh) 2006-02-09 2009-04-29 阿尔巴医疗公司 紧密连接效应子的制剂
BRPI0719319A2 (pt) * 2006-11-17 2014-02-04 Da Volterra Liberação colônica usando contas de zn/pectina com um revestimento de eudragit
DE102006062250A1 (de) 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden
US20080233184A1 (en) 2007-03-19 2008-09-25 Kenneth Looney Combination enzyme products
EP2143424A4 (en) * 2007-03-26 2013-07-31 Teikoku Seiyaku Kk ORAL PHARMACEUTICAL PREPARATION FOR SPECIFIC DELIVERY TO THE COLON
CN103120653B (zh) 2007-04-04 2015-09-30 希格默伊德药业有限公司 一种口服药物组合物
TW200904340A (en) 2007-05-11 2009-02-01 Mannatech Inc Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same
DK1992351T3 (en) 2007-05-18 2016-06-06 Nestec Sa Lactobacillus johnsonii for the prevention of post-surgical infection
EP1997499A1 (en) 2007-05-31 2008-12-03 Puleva Biotech, S.A. Mammalian milk microorganisms, compositions containing them and their use for the treatment of mastitis
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
US20090035370A1 (en) 2007-08-02 2009-02-05 Drugtech Corporation Dosage form and method of use
EP2022502A1 (en) 2007-08-10 2009-02-11 Nestec S.A. Lactobacillus rhamnosus and weight control
US9757346B2 (en) 2008-09-03 2017-09-12 Volant Holdings Gmbh Compositions and methods for treating insulin resistance and non-insulin dependent diabetes mellitus (type II diabetes)
WO2010027498A2 (en) 2008-09-03 2010-03-11 New Science Holdings, Llc Compositions and methods for inducing satiety and treating non-insulin dependent diabetes emillitus, pre-diabetic symptoms, insulin resistance and related disease states and conditions
WO2010054439A1 (en) 2008-11-14 2010-05-20 Unistraw Patent Holdings Limited Probiotic compositions, methods and apparatus for their administration
EP2216034A1 (en) 2009-02-10 2010-08-11 Nestec S.A. Lactobacillus helveticus CNCM I-4095 and weight control
US9474773B2 (en) 2009-02-18 2016-10-25 University Of Florida Research Foundation, Inc. Lactobacillus supplement for alleviating type 1 diabetes
FR2942719B1 (fr) 2009-03-04 2011-08-19 Oreal Utilisation de microorganismes probiotiques pour limiter les irritations cutanees
US8338162B2 (en) 2009-04-17 2012-12-25 Anaeropharma Science, Inc. Obligately anaerobic mutant lactic acid bacterium and preparation method therefor, and expression vector functioning in obligately anaerobic lactic acid bacterium
US20120276149A1 (en) 2009-10-15 2012-11-01 Dan Littman Methods for modulating bacterial infection
US8367418B2 (en) 2009-10-23 2013-02-05 Therasyn Sensors, Inc. Method and system to provide personalized pharmaceutical compositions and dosages
US8999721B2 (en) 2009-10-23 2015-04-07 Therabrake, Inc. Method and system to provide personalized pharmaceutical compositions and dosages
PT2538930T (pt) * 2010-02-23 2016-08-05 Da Volterra Formulações para administração oral de adsorventes no intestino
US20130273154A1 (en) 2011-03-02 2013-10-17 Joseph M. Fayad Oral formulations Mimetic of Roux-en-Y gastric bypass actions on the ileal brake; Compositions, Methods of Treatment, Diagnostics and Systems for treatment of metabolic syndrome manifestations including insulin resistance, fatty liver disease, hpperlipidemia, and type 2 diabetes
US9707207B2 (en) * 2010-05-26 2017-07-18 The United States Of America As Represented By The Department Of Veterans Affairs Method for diagnosing, preventing, and treating neurological diseases
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
EP2582387A2 (en) 2010-06-17 2013-04-24 The United States Of America As Represented By The Secretary, National Institutes Of Health Compositions and methods for treating inflammatory conditions
EP2397145A1 (en) 2010-06-18 2011-12-21 Nestec S.A. L. johnsonii La1, B. longum NCC2705 and immune disorders
CA2820178A1 (en) * 2010-12-06 2012-06-14 Degama Berrier Ltd. Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof
RU2442572C1 (ru) 2010-12-23 2012-02-20 Ольга Львовна Титова Энтеросолюбильная оболочка и композиция для ее получения
KR20190060879A (ko) 2011-03-02 2019-06-03 제롬 쉔타그 단독으로 또는 c형 간염 바이러스 감염과 결합되는 간 지방증의 치료를 위한 조성물, 방법 및 진단
GB2490671B (en) * 2011-05-09 2017-12-20 Mw Encap Ltd Dosage Unit for Administration of Antibiotics to the Small and Large Intestine
CA2848757C (en) 2011-09-14 2021-11-09 University Of Guelph Methods to culture human gastrointestinal microorganisms
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
CN104160014A (zh) 2011-12-01 2014-11-19 国立大学法人东京大学 诱导调节性t细胞的增殖或积累的人源细菌
CA2868362C (en) 2012-03-29 2018-07-31 Jerome Schentag Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
EP2943213A4 (en) 2013-01-08 2016-08-17 Jerome Schentag ACTIVATION OF THE ENDOGENOUS HORMONE PATHWAY OF ILLEAL BRAKE FOR THE REGENERATION OF AN ORGAN AND ASSOCIATED COMPOSITIONS, METHODS OF TREATMENT, DIAGNOSTICS, AND REGULATORY SYSTEMS
JP2016509003A (ja) 2013-02-04 2016-03-24 セレス セラピューティクス インコーポレイテッド 組成物および方法
WO2014121304A1 (en) 2013-02-04 2014-08-07 Seres Health, Inc. Compositions and methods
WO2014153194A2 (en) 2013-03-14 2014-09-25 Seres Health, Inc. Methods for pathogen detection and enrichment from materials and compositions
BR112015023124A2 (pt) 2013-03-14 2017-07-18 Therabiome Llc liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal
AU2014232370B2 (en) 2013-03-15 2018-11-01 Société des Produits Nestlé S.A. Network-based microbial compositions and methods
DK3074027T3 (da) 2013-11-25 2025-03-17 Nestle Sa Synergistiske bakteriesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf
WO2015095241A2 (en) 2013-12-16 2015-06-25 Seres Health, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders

Also Published As

Publication number Publication date
US10369111B2 (en) 2019-08-06
US20200138722A1 (en) 2020-05-07
JP6464142B2 (ja) 2019-02-06
NZ711298A (en) 2021-07-30
CA2904389C (en) 2018-09-18
CN105120847A (zh) 2015-12-02
US9907755B2 (en) 2018-03-06
AU2014239883A1 (en) 2015-10-29
US20160022592A1 (en) 2016-01-28
WO2014152338A1 (en) 2014-09-25
CA2904389A1 (en) 2014-09-25
JP2016517425A (ja) 2016-06-16
CN110075130A (zh) 2019-08-02
RU2015140610A (ru) 2017-04-17
US20180221286A1 (en) 2018-08-09
AU2020267253A1 (en) 2020-12-10
JP6860596B2 (ja) 2021-04-14
AU2018282453B2 (en) 2020-08-13
AU2014239883B2 (en) 2019-01-17
JP2019077705A (ja) 2019-05-23
EP2968187A1 (en) 2016-01-20
CN105120847B (zh) 2018-12-28
CA3101218A1 (en) 2014-09-25
HK1213805A1 (zh) 2016-07-15
AU2018282453A1 (en) 2019-01-24
US20230277468A1 (en) 2023-09-07
RU2015140610A3 (enExample) 2018-03-19
EP2968187A4 (en) 2016-08-17
CA3013541C (en) 2021-01-19
CA3013541A1 (en) 2014-09-25
US11590083B2 (en) 2023-02-28

Similar Documents

Publication Publication Date Title
BR112015023124A2 (pt) liberação de organismos probióticos e/ou agentes terapêuticos almejada para o trato gastrintestinal
BR112015002524A2 (pt) derivados de alquilpirimidina para o tratamento de infecções virais e outras doenças.
EP3164406C0 (en) BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES
BR112015001712A2 (pt) uso de s-pindolol para o tratamento da caquexia e sarcopenia
EP3540076C0 (en) METHODS AND PROCESSES FOR NON-INVASIVE EVALUATION OF GENETIC VARIATIONS
EP3578670C0 (en) METHODS AND PROCESSES FOR NON-INVASIVE EVALUATION OF GENETIC VARIATIONS
EP2946339A4 (en) BIOMETRIC IMAGING DEVICES AND CORRESPONDING METHODS
HUE043304T2 (hu) Baktérium probiotikumként történõ alkalmazásra táplálkozási és gyógyászati alkalmazásokra
HUE066811T2 (hu) Izoxazolin kompozíciók és azok felhasználása parazitafertõzések megelõzésében és kezelésében állatokban
HUE056006T2 (hu) Kombináció Parkinson-kór kezelésére
IL245183B (en) Methods of treating and preventing graft versus host disease
BR112013011932A2 (pt) dispositivo para tratamento de ejaculação precoce ou estímulo de órgão masculino
PT2928477T (pt) Utilização do inibidor da telomerase imetelstat para o tratamento de mielofibrose.
PT3192366T (pt) Sistema de libertação de ácaros benéficos e utilizações do mesmo
HUE040496T2 (hu) Vegyületek elhízás kezelésére és alkalmazási eljárásaik
EP3656377C0 (en) AQUEOUS FORMULATION COMPRISING PARACETAMOL AND IBUPROFEN
EP2970492A4 (en) ANTIBODY AGAINST HUMAN AND DOG IL-13RA2
HUE045025T2 (hu) Heterobiciklusos vegyületek és alkalmazásuk tuberkulózis kezelésére
IL234606B (en) Novel methods and composition for treatment of disease
BR112014009456A2 (pt) uso de melatonina para o tratamento e/ou prevenção de mucosite
BR112015003032A2 (pt) anticorpos anti-jagged e métodos de utilização'.
HUE042196T2 (hu) Vegyületek elhízás kezelésére és alkalmazási eljárásaik
DE112018002389A5 (de) Kupplungseinrichtung und Antriebsstrang
PT2895180T (pt) Composição para a prevenção e o tratamento de infeções agudas e recorrentes do trato urinário
PL2864455T3 (pl) Urządzenie i sposób obróbki cieplnej strumienia materiału

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements