BR112015004881A2 - método para diagnosticar o estado da doença periodontal e kit para diagnosticar o estado da doença periodontal - Google Patents

método para diagnosticar o estado da doença periodontal e kit para diagnosticar o estado da doença periodontal

Info

Publication number
BR112015004881A2
BR112015004881A2 BR112015004881A BR112015004881A BR112015004881A2 BR 112015004881 A2 BR112015004881 A2 BR 112015004881A2 BR 112015004881 A BR112015004881 A BR 112015004881A BR 112015004881 A BR112015004881 A BR 112015004881A BR 112015004881 A2 BR112015004881 A2 BR 112015004881A2
Authority
BR
Brazil
Prior art keywords
periodontal disease
periodontitis
disease status
diagnosing
diagnosing periodontal
Prior art date
Application number
BR112015004881A
Other languages
English (en)
Inventor
Creese Andrew
Leslie Campbell Chapple Iain
Mackay Grant Melissa
Original Assignee
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Nv filed Critical Koninklijke Philips Nv
Publication of BR112015004881A2 publication Critical patent/BR112015004881A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

resumo método para diagnosticar o estado da doença periodontal e kit para diagnosticar o estado da doença periodontal métodos para diagnosticar o estado da doença periodontal incluem selecionar um conjunto de biomarcadores de proteína incluindo um ou mais biomarcadores que mostraram variar em abundância em estágios particulares de periodontite. o conjunto de biomarcadores de proteína pode ser identificado e quantificado em expressão em um fluido crevicular gengival (gcf) adquirido ou amostra de saliva de fluido oral a fim de distinguir entre diferentes estados de periodontite. métodos para diagnosticar o estado da doença oral periodontal em níveis variáveis de gravidade, por exemplo, gengivite, periodontite leve, ou periodontite grave, podem incluir seleção de um conjunto de biomarcadores de proteína que são capazes de distinguir entre diferentes estágios de periodontite. 1/1
BR112015004881A 2012-09-10 2013-09-10 método para diagnosticar o estado da doença periodontal e kit para diagnosticar o estado da doença periodontal BR112015004881A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261699035P 2012-09-10 2012-09-10
PCT/IB2013/058431 WO2014037924A2 (en) 2012-09-10 2013-09-10 Analysis of saliva proteome for biomarkers of gingivitis and periodontitis using ft-icr-ms/ms

Publications (1)

Publication Number Publication Date
BR112015004881A2 true BR112015004881A2 (pt) 2017-07-04

Family

ID=49585455

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015004881A BR112015004881A2 (pt) 2012-09-10 2013-09-10 método para diagnosticar o estado da doença periodontal e kit para diagnosticar o estado da doença periodontal

Country Status (10)

Country Link
US (1) US20150219665A1 (pt)
EP (2) EP3396383A1 (pt)
JP (1) JP6402106B2 (pt)
KR (1) KR20150052311A (pt)
CN (1) CN104620110A (pt)
BR (1) BR112015004881A2 (pt)
CA (1) CA2884089A1 (pt)
IL (1) IL237600A0 (pt)
RU (1) RU2015113089A (pt)
WO (1) WO2014037924A2 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015240454B2 (en) 2014-04-04 2019-08-22 Mayo Foundation For Medical Education And Research Isotyping immunoglobulins using accurate molecular mass
CN106461658A (zh) * 2014-06-05 2017-02-22 高露洁-棕榄公司 用于口腔炎症的测定
KR20160060288A (ko) * 2014-11-20 2016-05-30 서울대학교산학협력단 Odam의 치주질환 바이오마커로서의 용도
WO2016095202A1 (en) * 2014-12-19 2016-06-23 The Procter & Gamble Company Gum condition assessment
EP3353200A4 (en) 2015-09-24 2019-06-26 Mayo Foundation for Medical Education and Research IDENTIFICATION OF FREE LIGHT CHAINS FROM IMMOBILIZED LOBULIN BY MASS SPECTROMETRY
CN106918706B (zh) * 2015-12-25 2019-05-21 广州瑞博奥生物科技有限公司 一种检测牙周病相关蛋白的抗体芯片试剂盒
MY196578A (en) * 2016-04-05 2023-04-19 Lion Corp Method for Determining Stage of Periodontal Disease
AU2017325022B2 (en) 2016-09-07 2022-10-13 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
JP6917722B2 (ja) * 2017-02-03 2021-08-11 花王株式会社 口腔の健康状態の評価方法
US20200088741A1 (en) * 2017-05-24 2020-03-19 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis based on salivary il-1beta and mmp-9
KR102079976B1 (ko) * 2017-08-08 2020-02-21 전남대학교 산학협력단 치주질환 진단용 바이오마커
US11946937B2 (en) 2017-09-13 2024-04-02 Mayo Foundation For Medical Education And Research Identification and monitoring of apoptosis inhibitor of macrophage
CN111226118A (zh) * 2017-10-27 2020-06-02 加利福尼亚大学董事会 用于牙龈炎的唾液细胞外rna生物标记物
EP3477306A1 (en) * 2017-10-30 2019-05-01 Koninklijke Philips N.V. Classification of periodontitis patients
KR102009016B1 (ko) * 2017-12-06 2019-08-08 고려대학교 산학협력단 오담(ODAM, Odontogenic Ameloblast-Associated protein)에 특이적으로 결합하는 DNA 앱타머 및 그의 용도
EP3511716A1 (en) * 2018-01-16 2019-07-17 Koninklijke Philips N.V. Periodontitis diagnostic methods, uses and kits
EP3511715A1 (en) * 2018-01-16 2019-07-17 Koninklijke Philips N.V. Periodontal disease diagnostic methods, uses and kits
EP3553526A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Methods, uses and kits for monitoring or predicting response to periodontal disease treatment
EP3553523A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis
EP3553524A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Periodontitis diagnostic methods, uses and kits
EP3553518A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Periodontitis diagnostic methods, uses and kits
EP3553525A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis
EP3553522A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Gingivitis diagnostic methods, uses and kits
EP3553520A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Methods, uses and kits for monitoring or predicting response to periodontal disease treatment
EP3553521A1 (en) * 2018-04-12 2019-10-16 Koninklijke Philips N.V. Gingivitis diagnostic methods, uses and kits
KR102500669B1 (ko) * 2018-08-23 2023-02-16 서울대학교산학협력단 타액 중의 s100 단백질을 이용한 초기 치주염의 진단방법, 정보제공방법, 조성물 및 키트
AU2019417313B2 (en) * 2018-12-26 2023-01-19 Colgate-Palmolive Company Biomarkers of neutrophil deregulation as diagnostic for gingivitis
CN110441438A (zh) * 2019-09-09 2019-11-12 大连医科大学附属第一医院 一种基于s100蛋白家族的急性胰腺炎严重程度预测模型及其检测方法
KR102266531B1 (ko) * 2019-11-12 2021-06-21 아주대학교산학협력단 타액 단백질 마커를 이용한 잇몸 상태의 진단방법
WO2022096893A1 (en) 2020-11-04 2022-05-12 The University Of Birmingham Device
KR102460127B1 (ko) * 2022-05-25 2022-10-28 주식회사 바질바이오텍 치주 질환 진단용 바이오마커 및 이의 용도
KR20240025138A (ko) 2022-08-18 2024-02-27 부산대학교 산학협력단 치주염 진단용 바이오마커 조성물 및 이를 이용한 치주염 진단용 키트
CN115980368B (zh) * 2023-02-08 2023-11-21 重庆医科大学附属口腔医院 一种用于牙周炎检测的标记物组

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995012124A1 (en) * 1993-10-29 1995-05-04 Institute Of Molecular Biology, Inc. Osteocalcin as a marker of periodontal and peri-implant disease activity
JP2930427B2 (ja) * 1995-04-12 1999-08-03 オイ メディックス バイオケミカ エービー 歯周疾患を判断するためのおよびその疾患が進行する危険を予報するための方法とその試験キット
JP4590581B2 (ja) * 2000-12-13 2010-12-01 合同酒精株式会社 唾液成分の免疫学的測定法
US20040181344A1 (en) * 2002-01-29 2004-09-16 Massachusetts Institute Of Technology Systems and methods for providing diagnostic services
JP4252812B2 (ja) * 2003-01-29 2009-04-08 株式会社ビー・エム・エル 歯周病菌の定量方法
JP2005201768A (ja) * 2004-01-15 2005-07-28 Bml Inc 歯周疾患の検出方法
WO2009018342A1 (en) * 2007-07-30 2009-02-05 The Regents Of The University Of Michigan Multi-analyte analysis of saliva biomarkers as predictors of periodontal and peri-implant disease
JP2009145220A (ja) * 2007-12-14 2009-07-02 Lion Corp 歯周病の診断方法及び歯周病診断キット
EP2281201B1 (en) * 2008-05-14 2018-03-28 ETH Zurich Method for biomarker and drug-target discovery for prostate cancer diagnosis and treatment as well as biomarker assays determined therewith
KR101222437B1 (ko) * 2010-03-17 2013-01-15 경북대학교 산학협력단 바이오마커
KR20110135911A (ko) * 2011-12-05 2011-12-20 경북대학교 산학협력단 바이오마커

Also Published As

Publication number Publication date
EP3396383A1 (en) 2018-10-31
JP2015529333A (ja) 2015-10-05
RU2015113089A (ru) 2016-10-27
IL237600A0 (en) 2015-04-30
EP2893353A2 (en) 2015-07-15
KR20150052311A (ko) 2015-05-13
WO2014037924A2 (en) 2014-03-13
JP6402106B2 (ja) 2018-10-10
US20150219665A1 (en) 2015-08-06
CA2884089A1 (en) 2014-03-13
CN104620110A (zh) 2015-05-13
WO2014037924A3 (en) 2014-05-22

Similar Documents

Publication Publication Date Title
BR112015004881A2 (pt) método para diagnosticar o estado da doença periodontal e kit para diagnosticar o estado da doença periodontal
Eriksson et al. Saliva and tooth biofilm bacterial microbiota in adolescents in a low caries community
AR048234A1 (es) Composiciones para revestir dientes y metodos para ello.
CY1120961T1 (el) Δοσολογικες μορφες απο του στοματος που περιλαμβανουν αντιαιμοπεταλιακο παραγοντα και αναστολεα οξεος
WO2014060549A3 (en) Statistical linguistic analysis of source content
BR112018015698A2 (pt) ?métodos diagnósticos e prognósticos para doenças cardiovasculares e eventos?
BRPI0909620A2 (pt) "dispositivo microfluídico para detectar a presença de um ou mais análitos em uma amostra de saliva, método para detectar a presença de um ou mais análitos em uma amostra de saliva e método para detectar em um dispositivo microfluídico um análito e uma amostra de saliva que copreende a mucina"
BRPI0513897A (pt) diferenciação de células-tronco
PT2129391E (pt) Método de diagnóstico
CL2004000934A1 (es) Conjunto de elementos que comprende cebadores para reconocer la linea de maiz tc1507, metodo para detectar la linea de maiz tc1507 o la progenie del mismo en una muestra biologica.
BRPI1013688A8 (pt) Proteínas de ligação de il-17.
WO2009015084A3 (en) Methods for generating a standard reference die for use in a die to standard reference die inspection and methods for inspecting a wafer
BR112012031071A2 (pt) 8-proteínas de ligação à il-1
DE602006019307D1 (de) Indentifizierung von menschen durch charakteristische verbindungen aus dem menschlichen duft
BRPI0506161A (pt) composição que pode ser misturada com um fluido, e, bebida
BR112016005064A2 (pt) método para avaliar os efeitos de uma composição compreendendo microrganismos em microbiota intestinal
AR093716A1 (es) Composicion de cuidado oral
BR112014027489A2 (pt) um eletrodo e seu uso
BR122019018448B8 (pt) método para extração de succinilacetona e um ou mais analitos biológicos adicionais
FR2900936B1 (fr) Procede et methodes de detection de la maladie d'alzheimer
BR112014002406A2 (pt) método para promoção de higiene e limpeza
ES2421595T3 (es) Métodos para modular receptores de superficie celular para prevenir o reducir la inflamación
ATE467128T1 (de) Kolloidale metallkonjugate
BR112017000490A2 (pt) componente condutor de fluxo
DE602005013430D1 (de) Verwendung von asc als marker für kolorektalkarzinome

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2531 DE 09-07-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.