BR112014024601B1 - Oligonucleotídeo modificado composto de funções tióis; substrato enxertado com oligonucleotídeo modificado; método e kit de detecção de ácido nucleico em uma amostra de oligonucleotídeo modificado; e o uso oligonucleotídeo modificado para a detecção de ácidos nucleicos - Google Patents

Oligonucleotídeo modificado composto de funções tióis; substrato enxertado com oligonucleotídeo modificado; método e kit de detecção de ácido nucleico em uma amostra de oligonucleotídeo modificado; e o uso oligonucleotídeo modificado para a detecção de ácidos nucleicos Download PDF

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Publication number
BR112014024601B1
BR112014024601B1 BR112014024601-7A BR112014024601A BR112014024601B1 BR 112014024601 B1 BR112014024601 B1 BR 112014024601B1 BR 112014024601 A BR112014024601 A BR 112014024601A BR 112014024601 B1 BR112014024601 B1 BR 112014024601B1
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Brazil
Prior art keywords
identification number
sequence identification
modified oligonucleotide
sequence
groups
Prior art date
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BR112014024601-7A
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English (en)
Portuguese (pt)
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BR112014024601A2 (pt
Inventor
Chantal Fournier-Wirth
Myriam Lereau
Jean-François Cantaloube
Jean-Jacques Vasseur
François Morvan
Albert Meyer
Julie Mayen
Carole Chaix
Carole Farre
Original Assignee
Etablissement Français Du Sang
Centre National De La Recherche Scientifique (Cnrs)
Universite Claude Bernard Lyon 1
Université De Montpellier
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Application filed by Etablissement Français Du Sang, Centre National De La Recherche Scientifique (Cnrs), Universite Claude Bernard Lyon 1, Université De Montpellier filed Critical Etablissement Français Du Sang
Publication of BR112014024601A2 publication Critical patent/BR112014024601A2/pt
Publication of BR112014024601B1 publication Critical patent/BR112014024601B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
BR112014024601-7A 2012-04-04 2013-04-04 Oligonucleotídeo modificado composto de funções tióis; substrato enxertado com oligonucleotídeo modificado; método e kit de detecção de ácido nucleico em uma amostra de oligonucleotídeo modificado; e o uso oligonucleotídeo modificado para a detecção de ácidos nucleicos BR112014024601B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1253122 2012-04-04
FR1253122A FR2989089B1 (fr) 2012-04-04 2012-04-04 Oligonucleotides modifies comprenant des fonctions thiol et leur utilisation pour la detection d'acides nucleiques
PCT/EP2013/057150 WO2013150122A1 (fr) 2012-04-04 2013-04-04 Oligonucleotides modifies compenant des fonctions thiol et leur utilisation pour la detection d'acides nucleiques

Publications (2)

Publication Number Publication Date
BR112014024601A2 BR112014024601A2 (pt) 2018-04-17
BR112014024601B1 true BR112014024601B1 (pt) 2022-05-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014024601-7A BR112014024601B1 (pt) 2012-04-04 2013-04-04 Oligonucleotídeo modificado composto de funções tióis; substrato enxertado com oligonucleotídeo modificado; método e kit de detecção de ácido nucleico em uma amostra de oligonucleotídeo modificado; e o uso oligonucleotídeo modificado para a detecção de ácidos nucleicos

Country Status (12)

Country Link
US (2) US20150232957A1 (enExample)
EP (1) EP2859008B1 (enExample)
JP (1) JP6175489B2 (enExample)
KR (1) KR102186143B1 (enExample)
AU (1) AU2013244900B2 (enExample)
BR (1) BR112014024601B1 (enExample)
CA (1) CA2868926C (enExample)
EA (1) EA029907B1 (enExample)
ES (1) ES2624993T3 (enExample)
FR (1) FR2989089B1 (enExample)
IN (1) IN2014DN08170A (enExample)
WO (1) WO2013150122A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017218293A1 (en) 2016-06-16 2017-12-21 Richard Edward Watts Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules
WO2018204420A1 (en) 2017-05-02 2018-11-08 Haystack Sciences Corporation Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same
JP7282379B2 (ja) * 2017-08-22 2023-05-29 国立大学法人東海国立大学機構 修飾ポリヌクレオチド
US20200263163A1 (en) * 2017-09-25 2020-08-20 Haystack Sciences Corporation Multinomial encoding for oligonucleotide-directed combinatorial chemistry
EP4305198A1 (en) 2021-03-09 2024-01-17 Etablissement Français du Sang Detection of infectious agent based on recombinase polymerase amplification combined with a magnetic field-enhanced agglutination

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041183A (ja) * 1983-08-16 1985-03-04 三菱電機株式会社 入場管理装置
IE922292A1 (en) * 1991-07-15 1993-01-27 Jolla Pharma Modified phosphorous intermediates for providing functional¹groups on the 5' end of oligonucleotides
JPH0641183A (ja) * 1992-07-23 1994-02-15 Mitsubishi Kasei Corp オリゴヌクレオチド単分子膜
DE10163836A1 (de) * 2001-12-22 2003-07-10 Friz Biochem Gmbh Multifunktionales Reagenz zur Synthese von thiolmodifizierten Oligomeren
US7371585B2 (en) * 2003-12-31 2008-05-13 Genencor International, Inc. Membranes incorporating recognition moieties
US7167395B1 (en) 2005-07-13 2007-01-23 Infineon Technologies Flash Gmbh & Co. Kg Non-volatile semiconductor memory
AU2006330464A1 (en) 2005-12-23 2007-07-05 Siemens Healthcare Diagnostics Inc. Methods and reagents for genotyping HCV
FR2989086B1 (fr) 2012-04-04 2017-03-24 Centre Nat De La Rech Scient (Cnrs) Composes thiol et leur utilisation pour la synthese d'oligonucleotides modifies

Also Published As

Publication number Publication date
CA2868926A1 (fr) 2013-10-10
US20190376151A1 (en) 2019-12-12
ES2624993T3 (es) 2017-07-18
FR2989089A1 (fr) 2013-10-11
JP2015514402A (ja) 2015-05-21
KR102186143B1 (ko) 2020-12-03
IN2014DN08170A (enExample) 2015-05-01
JP6175489B2 (ja) 2017-08-02
KR20150021493A (ko) 2015-03-02
EA201491821A1 (ru) 2015-02-27
CA2868926C (fr) 2021-05-04
EA029907B1 (ru) 2018-05-31
EP2859008B1 (fr) 2017-02-22
US11390643B2 (en) 2022-07-19
BR112014024601A2 (pt) 2018-04-17
FR2989089B1 (fr) 2020-02-07
US20150232957A1 (en) 2015-08-20
AU2013244900A1 (en) 2014-10-16
AU2013244900B2 (en) 2017-01-12
EP2859008A1 (fr) 2015-04-15
WO2013150122A1 (fr) 2013-10-10

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Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: ETABLISSEMENT FRANCAIS DU SANG (FR) ; CENTRE NATIO

Owner name: ETABLISSEMENT FRANCAIS DU SANG (FR) ; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) ; UNIVERSITE CLAUDE BERNARD LYON 1 (FR) ; UNIVERSITE DE MONTPELLIER (FR)

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/04/2013, OBSERVADAS AS CONDICOES LEGAIS