KR102186143B1 - 티올 관능기를 포함하는 개질된 올리고뉴클레오티드 및 이를 이용한 핵산의 검출 - Google Patents

티올 관능기를 포함하는 개질된 올리고뉴클레오티드 및 이를 이용한 핵산의 검출 Download PDF

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KR102186143B1
KR102186143B1 KR1020147027987A KR20147027987A KR102186143B1 KR 102186143 B1 KR102186143 B1 KR 102186143B1 KR 1020147027987 A KR1020147027987 A KR 1020147027987A KR 20147027987 A KR20147027987 A KR 20147027987A KR 102186143 B1 KR102186143 B1 KR 102186143B1
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샹딸 푸르니에-워스
밀리암 르루오
장-프랑수아 칸탈로베
장-자크 바세르
프랑수아 모르방
알베르트 메이어
줄리 마옌
카롤 샤이스
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에따블리스망 프랑스와 뒤 상
쌍트르 나쉬오날 드 라 르쉐르스 쉬앙티피끄
위니베르시테 끌로드 베르나르 리옹 Ⅰ
위니베르시테 드 몽펠리에
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
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  • Genetics & Genomics (AREA)
  • Immunology (AREA)
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  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
KR1020147027987A 2012-04-04 2013-04-04 티올 관능기를 포함하는 개질된 올리고뉴클레오티드 및 이를 이용한 핵산의 검출 Active KR102186143B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1253122 2012-04-04
FR1253122A FR2989089B1 (fr) 2012-04-04 2012-04-04 Oligonucleotides modifies comprenant des fonctions thiol et leur utilisation pour la detection d'acides nucleiques
PCT/EP2013/057150 WO2013150122A1 (fr) 2012-04-04 2013-04-04 Oligonucleotides modifies compenant des fonctions thiol et leur utilisation pour la detection d'acides nucleiques

Publications (2)

Publication Number Publication Date
KR20150021493A KR20150021493A (ko) 2015-03-02
KR102186143B1 true KR102186143B1 (ko) 2020-12-03

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US (2) US20150232957A1 (enExample)
EP (1) EP2859008B1 (enExample)
JP (1) JP6175489B2 (enExample)
KR (1) KR102186143B1 (enExample)
AU (1) AU2013244900B2 (enExample)
BR (1) BR112014024601B1 (enExample)
CA (1) CA2868926C (enExample)
EA (1) EA029907B1 (enExample)
ES (1) ES2624993T3 (enExample)
FR (1) FR2989089B1 (enExample)
IN (1) IN2014DN08170A (enExample)
WO (1) WO2013150122A1 (enExample)

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WO2017218293A1 (en) 2016-06-16 2017-12-21 Richard Edward Watts Oligonucleotide directed and recorded combinatorial synthesis of encoded probe molecules
WO2018204420A1 (en) 2017-05-02 2018-11-08 Haystack Sciences Corporation Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same
JP7282379B2 (ja) * 2017-08-22 2023-05-29 国立大学法人東海国立大学機構 修飾ポリヌクレオチド
US20200263163A1 (en) * 2017-09-25 2020-08-20 Haystack Sciences Corporation Multinomial encoding for oligonucleotide-directed combinatorial chemistry
EP4305198A1 (en) 2021-03-09 2024-01-17 Etablissement Français du Sang Detection of infectious agent based on recombinase polymerase amplification combined with a magnetic field-enhanced agglutination

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JPS6041183A (ja) * 1983-08-16 1985-03-04 三菱電機株式会社 入場管理装置
IE922292A1 (en) * 1991-07-15 1993-01-27 Jolla Pharma Modified phosphorous intermediates for providing functional¹groups on the 5' end of oligonucleotides
JPH0641183A (ja) * 1992-07-23 1994-02-15 Mitsubishi Kasei Corp オリゴヌクレオチド単分子膜
DE10163836A1 (de) * 2001-12-22 2003-07-10 Friz Biochem Gmbh Multifunktionales Reagenz zur Synthese von thiolmodifizierten Oligomeren
US7371585B2 (en) * 2003-12-31 2008-05-13 Genencor International, Inc. Membranes incorporating recognition moieties
US7167395B1 (en) 2005-07-13 2007-01-23 Infineon Technologies Flash Gmbh & Co. Kg Non-volatile semiconductor memory
AU2006330464A1 (en) 2005-12-23 2007-07-05 Siemens Healthcare Diagnostics Inc. Methods and reagents for genotyping HCV
FR2989086B1 (fr) 2012-04-04 2017-03-24 Centre Nat De La Rech Scient (Cnrs) Composes thiol et leur utilisation pour la synthese d'oligonucleotides modifies

Non-Patent Citations (1)

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Title
FEBS Lett., 1993, vol.336, no.3, pp.452-456

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Publication number Publication date
CA2868926A1 (fr) 2013-10-10
US20190376151A1 (en) 2019-12-12
ES2624993T3 (es) 2017-07-18
FR2989089A1 (fr) 2013-10-11
BR112014024601B1 (pt) 2022-05-24
JP2015514402A (ja) 2015-05-21
IN2014DN08170A (enExample) 2015-05-01
JP6175489B2 (ja) 2017-08-02
KR20150021493A (ko) 2015-03-02
EA201491821A1 (ru) 2015-02-27
CA2868926C (fr) 2021-05-04
EA029907B1 (ru) 2018-05-31
EP2859008B1 (fr) 2017-02-22
US11390643B2 (en) 2022-07-19
BR112014024601A2 (pt) 2018-04-17
FR2989089B1 (fr) 2020-02-07
US20150232957A1 (en) 2015-08-20
AU2013244900A1 (en) 2014-10-16
AU2013244900B2 (en) 2017-01-12
EP2859008A1 (fr) 2015-04-15
WO2013150122A1 (fr) 2013-10-10

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