BR112013007247A2 - polipeptídeo de seda de aranha quimérico, fibra compósita, bicho-da-seda transgênico, ácido nucleico que codifica um polipeptídeo de seda de aranha quimérico, vetor piggybac, método pra produzir uma fibra de seda de aranha quimérica e método para preparar um bicho-da-seda bombyx mori trangênico capaz de expressar estavelmente um poliptídeo de seda de aranha quimérico adequado para montagem em uma fibra de seda de aranha quimérica - Google Patents
polipeptídeo de seda de aranha quimérico, fibra compósita, bicho-da-seda transgênico, ácido nucleico que codifica um polipeptídeo de seda de aranha quimérico, vetor piggybac, método pra produzir uma fibra de seda de aranha quimérica e método para preparar um bicho-da-seda bombyx mori trangênico capaz de expressar estavelmente um poliptídeo de seda de aranha quimérico adequado para montagem em uma fibra de seda de aranha quiméricaInfo
- Publication number
- BR112013007247A2 BR112013007247A2 BR112013007247A BR112013007247A BR112013007247A2 BR 112013007247 A2 BR112013007247 A2 BR 112013007247A2 BR 112013007247 A BR112013007247 A BR 112013007247A BR 112013007247 A BR112013007247 A BR 112013007247A BR 112013007247 A2 BR112013007247 A2 BR 112013007247A2
- Authority
- BR
- Brazil
- Prior art keywords
- spider silk
- chimeric spider
- fiber
- chimeric
- silkworm
- Prior art date
Links
- 229920001872 Spider silk Polymers 0.000 title 5
- 241000255789 Bombyx mori Species 0.000 title 3
- 239000000835 fiber Substances 0.000 title 3
- 229920001184 polypeptide Polymers 0.000 title 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 3
- 230000009261 transgenic effect Effects 0.000 title 2
- 239000002131 composite material Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43586—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from silkworms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/04—Silkworms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
- C07K4/12—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- D—TEXTILES; PAPER
- D02—YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
- D02G—CRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
- D02G3/00—Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
- D02G3/02—Yarns or threads characterised by the material or by the materials from which they are made
- D02G3/04—Blended or other yarns or threads containing components made from different materials
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Insects & Arthropods (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Mechanical Engineering (AREA)
- Textile Engineering (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Artificial Filaments (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38733210P | 2010-09-28 | 2010-09-28 | |
PCT/US2011/053760 WO2012050919A2 (en) | 2010-09-28 | 2011-09-28 | Chimeric spider silk and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013007247A2 true BR112013007247A2 (pt) | 2016-06-14 |
Family
ID=45938877
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013007247A BR112013007247A2 (pt) | 2010-09-28 | 2011-09-28 | polipeptídeo de seda de aranha quimérico, fibra compósita, bicho-da-seda transgênico, ácido nucleico que codifica um polipeptídeo de seda de aranha quimérico, vetor piggybac, método pra produzir uma fibra de seda de aranha quimérica e método para preparar um bicho-da-seda bombyx mori trangênico capaz de expressar estavelmente um poliptídeo de seda de aranha quimérico adequado para montagem em uma fibra de seda de aranha quimérica |
Country Status (9)
Country | Link |
---|---|
US (6) | US20130212718A1 (pt) |
EP (1) | EP2621957B1 (pt) |
JP (3) | JP2014502140A (pt) |
KR (3) | KR20140095010A (pt) |
CN (3) | CN109136245A (pt) |
AU (3) | AU2011314072B2 (pt) |
BR (1) | BR112013007247A2 (pt) |
CA (1) | CA2812791C (pt) |
WO (1) | WO2012050919A2 (pt) |
Families Citing this family (41)
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BR112013007247A2 (pt) * | 2010-09-28 | 2016-06-14 | Univ Notre Dame | polipeptídeo de seda de aranha quimérico, fibra compósita, bicho-da-seda transgênico, ácido nucleico que codifica um polipeptídeo de seda de aranha quimérico, vetor piggybac, método pra produzir uma fibra de seda de aranha quimérica e método para preparar um bicho-da-seda bombyx mori trangênico capaz de expressar estavelmente um poliptídeo de seda de aranha quimérico adequado para montagem em uma fibra de seda de aranha quimérica |
CN102358902B (zh) * | 2011-04-02 | 2013-01-02 | 西南大学 | 家蚕丝素重链基因突变序列及突变的方法和应用 |
JP5540154B2 (ja) | 2011-06-01 | 2014-07-02 | スパイバー株式会社 | 人造ポリペプチド繊維 |
CN102808033B (zh) * | 2012-08-29 | 2014-07-16 | 苏州大学 | 一种在幼虫期鉴别家蚕吐丝颜色的方法 |
CN102808034B (zh) * | 2012-08-29 | 2014-02-26 | 苏州大学 | 一种在蚕卵期鉴别家蚕吐丝颜色的方法 |
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WO2018183946A1 (en) * | 2017-03-30 | 2018-10-04 | Utah State University | Transgenic silkworms expressing spider silk |
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US20050261479A1 (en) * | 2004-04-29 | 2005-11-24 | Christian Hoffmann | Method for purifying and recovering silk proteins using magnetic affinity separation |
AU2005263622B2 (en) * | 2004-07-22 | 2012-04-26 | Amsilk Gmbh | Recombinant spider silk proteins |
BRPI0701826B1 (pt) * | 2007-03-16 | 2021-02-17 | Embrapa - Empresa Brasileira De Pesquisa Agropecuária | proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira |
WO2009009754A2 (en) * | 2007-07-12 | 2009-01-15 | Cornell Research Foundation, Inc. | Semantic transactions in online applications |
EP2244563B1 (en) * | 2008-02-01 | 2019-08-28 | Bogin, Robert | Methods, compositions, and systems for production of recombinant spider silk polypeptides |
JP5848749B2 (ja) * | 2010-03-29 | 2016-01-27 | ジェームス カービイ,エリック | ライブイベントの発生 |
BR112013007247A2 (pt) * | 2010-09-28 | 2016-06-14 | Univ Notre Dame | polipeptídeo de seda de aranha quimérico, fibra compósita, bicho-da-seda transgênico, ácido nucleico que codifica um polipeptídeo de seda de aranha quimérico, vetor piggybac, método pra produzir uma fibra de seda de aranha quimérica e método para preparar um bicho-da-seda bombyx mori trangênico capaz de expressar estavelmente um poliptídeo de seda de aranha quimérico adequado para montagem em uma fibra de seda de aranha quimérica |
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2011
- 2011-09-28 BR BR112013007247A patent/BR112013007247A2/pt not_active Application Discontinuation
- 2011-09-28 KR KR1020137010776A patent/KR20140095010A/ko active Application Filing
- 2011-09-28 KR KR1020187034773A patent/KR102063002B1/ko active IP Right Grant
- 2011-09-28 AU AU2011314072A patent/AU2011314072B2/en active Active
- 2011-09-28 CN CN201811026107.8A patent/CN109136245A/zh active Pending
- 2011-09-28 WO PCT/US2011/053760 patent/WO2012050919A2/en active Application Filing
- 2011-09-28 JP JP2013530432A patent/JP2014502140A/ja active Pending
- 2011-09-28 CN CN2011800571271A patent/CN103261231A/zh active Pending
- 2011-09-28 EP EP11833071.1A patent/EP2621957B1/en active Active
- 2011-09-28 CN CN201710335250.4A patent/CN107190017A/zh active Pending
- 2011-09-28 CA CA2812791A patent/CA2812791C/en active Active
- 2011-09-28 KR KR1020177005086A patent/KR101926286B1/ko active IP Right Grant
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2013
- 2013-03-28 US US13/852,379 patent/US20130212718A1/en not_active Abandoned
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2015
- 2015-06-30 US US14/754,916 patent/US20150322121A1/en not_active Abandoned
- 2015-06-30 US US14/754,946 patent/US20150322122A1/en not_active Abandoned
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2017
- 2017-03-01 JP JP2017038829A patent/JP2017127309A/ja active Pending
- 2017-03-03 AU AU2017201493A patent/AU2017201493A1/en not_active Abandoned
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2018
- 2018-12-14 US US16/221,267 patent/US20190106467A1/en not_active Abandoned
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2019
- 2019-01-11 US US16/246,318 patent/US20190153047A1/en not_active Abandoned
- 2019-02-13 US US16/275,159 patent/US20190185528A1/en not_active Abandoned
- 2019-03-05 AU AU2019201497A patent/AU2019201497A1/en not_active Abandoned
- 2019-08-02 JP JP2019142869A patent/JP2019205463A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2014502140A (ja) | 2014-01-30 |
KR20140095010A (ko) | 2014-07-31 |
EP2621957A2 (en) | 2013-08-07 |
EP2621957A4 (en) | 2014-03-26 |
JP2019205463A (ja) | 2019-12-05 |
WO2012050919A3 (en) | 2012-12-27 |
CN103261231A (zh) | 2013-08-21 |
US20130212718A1 (en) | 2013-08-15 |
CN109136245A (zh) | 2019-01-04 |
US20190106467A1 (en) | 2019-04-11 |
US20150322122A1 (en) | 2015-11-12 |
KR20180130603A (ko) | 2018-12-07 |
JP2017127309A (ja) | 2017-07-27 |
US20190185528A1 (en) | 2019-06-20 |
WO2012050919A2 (en) | 2012-04-19 |
CA2812791C (en) | 2020-07-14 |
AU2011314072A1 (en) | 2013-05-23 |
AU2011314072B2 (en) | 2017-03-30 |
AU2019201497A1 (en) | 2019-04-11 |
KR102063002B1 (ko) | 2020-01-07 |
US20190153047A1 (en) | 2019-05-23 |
EP2621957B1 (en) | 2021-06-02 |
CA2812791A1 (en) | 2012-04-19 |
KR101926286B1 (ko) | 2018-12-10 |
CN107190017A (zh) | 2017-09-22 |
AU2017201493A1 (en) | 2017-03-23 |
US20150322121A1 (en) | 2015-11-12 |
KR20170023415A (ko) | 2017-03-03 |
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