BR112012012603B1 - Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica - Google Patents

Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica Download PDF

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Publication number
BR112012012603B1
BR112012012603B1 BR112012012603-2A BR112012012603A BR112012012603B1 BR 112012012603 B1 BR112012012603 B1 BR 112012012603B1 BR 112012012603 A BR112012012603 A BR 112012012603A BR 112012012603 B1 BR112012012603 B1 BR 112012012603B1
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BR
Brazil
Prior art keywords
zeolite
fact
thermoplastic polymer
particles
peek
Prior art date
Application number
BR112012012603-2A
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English (en)
Portuguese (pt)
Other versions
BR112012012603A2 (pt
Inventor
Joseph J. Crudden
Derrick Johns
Original Assignee
Difusion Technologies, Inc.
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Application filed by Difusion Technologies, Inc. filed Critical Difusion Technologies, Inc.
Publication of BR112012012603A2 publication Critical patent/BR112012012603A2/pt
Publication of BR112012012603B1 publication Critical patent/BR112012012603B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/443—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
  • Polymers & Plastics (AREA)
  • Dental Preparations (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BR112012012603-2A 2009-11-25 2010-11-24 Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica BR112012012603B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26428909P 2009-11-25 2009-11-25
US61/264,289 2009-11-25
US30063110P 2010-02-02 2010-02-02
US61/300,631 2010-02-02
PCT/US2010/058009 WO2011066391A2 (en) 2009-11-25 2010-11-24 Post-charging of zeolite doped plastics with antimicrobial metal ions

Publications (2)

Publication Number Publication Date
BR112012012603A2 BR112012012603A2 (pt) 2017-11-21
BR112012012603B1 true BR112012012603B1 (pt) 2019-03-19

Family

ID=44067221

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012012603-2A BR112012012603B1 (pt) 2009-11-25 2010-11-24 Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica

Country Status (7)

Country Link
US (4) US9492584B2 (OSRAM)
EP (1) EP2504041B1 (OSRAM)
CN (2) CN102802685B (OSRAM)
BR (1) BR112012012603B1 (OSRAM)
IN (1) IN2012DN04965A (OSRAM)
RU (1) RU2552939C2 (OSRAM)
WO (1) WO2011066391A2 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2526168C2 (ru) 2009-12-11 2014-08-20 Дифьюжн Текнолоджиз, Инк. Способ получения противомикробных имплантатов из полиэфирэфиркетона
EP2571542B1 (en) 2010-05-07 2018-06-20 Difusion Technologies Inc. Medical implants with increased hydrophilicity
WO2014152653A1 (en) * 2013-03-14 2014-09-25 Difusion Technologies, Inc. Self sterilizing orthopedic implants
WO2014152649A1 (en) * 2013-03-15 2014-09-25 Difusion Technologies, Inc. Enhanced efficacy self-sterilizing orthopedic implants
US20200010728A1 (en) * 2017-02-09 2020-01-09 Femasys, Inc. Methods and compositions comprising biodegradable cyanoacrylates
US10751196B1 (en) 2017-10-24 2020-08-25 Omnia Medical, LLC Multi-material multi-component spinal implant
US11766339B1 (en) 2017-10-24 2023-09-26 Omnia Medical, LLC Multi-material multi-component spinal implant
EP3746139B1 (en) * 2018-02-02 2023-07-05 Evonik Operations GmbH Functionally graded polymer knee implant for enhanced fixation, wear resistance, and mechanical properties and the fabrication thereof
FR3084351B1 (fr) 2018-07-26 2021-04-02 Enercat Zeolithe dopee par un cation de metal de transition et modifiee par un ammonium quaternaire, preparation et utilisation
US11439726B2 (en) 2018-12-03 2022-09-13 Osseomimetic, LLC Surgical implants
US20210402052A1 (en) 2020-06-30 2021-12-30 Difusion, Inc. Medical Implants And Methods Of Manufacture
CN112608230A (zh) * 2020-11-17 2021-04-06 银金达(上海)新材料有限公司 一种低金属离子petg材料及其应用
WO2023200847A1 (en) * 2022-04-14 2023-10-19 Difusion, Inc. Surgical implants with enhanced osseointegration and methods of manufacture

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4088737A (en) 1976-11-02 1978-05-09 The United States Of America As Represented By The United States Department Of Energy Dry method for recycling iodine-loaded silver zeolite
JPS57500588A (OSRAM) 1980-03-27 1982-04-08
DE3228849C2 (de) 1982-08-02 1989-06-08 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München In den Körper einzuführendes medizinisches Gerät
WO1984001721A1 (en) 1982-11-05 1984-05-10 Baxter Travenol Lab Antimicrobial compositions
JPS59133235A (ja) * 1983-01-21 1984-07-31 Kanebo Ltd 殺菌性ポリマー組成物及びその製造法
US4596574A (en) 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
US4612337A (en) 1985-05-30 1986-09-16 The Trustees Of Columbia University In The City Of New York Method for preparing infection-resistant materials
GB2190383B (en) 1986-04-08 1990-03-28 Dentsply Ltd Glass/poly (carboxylic acid)cement compositions
JPS6323960A (ja) * 1986-07-16 1988-02-01 Zenji Hagiwara 非晶質アルミノ珪酸塩粒子を含有する高分子体及びその製造方法
US4938958A (en) 1986-12-05 1990-07-03 Shinagawa Fuel Co., Ltd. Antibiotic zeolite
US4775586A (en) 1987-02-17 1988-10-04 Armstrong World Industries, Inc. Paper, paper products, films composites and other silicate-polymer, construction materials
JPS63265958A (ja) 1987-04-22 1988-11-02 Shinagawa Nenryo Kk 抗菌性樹脂組成物
JPH0618899B2 (ja) 1987-06-30 1994-03-16 品川燃料株式会社 抗菌性ゼオライト含有フィルム
JPS6415056A (en) 1987-07-09 1989-01-19 Hanarou Maeda Body indwelling tube
JPH0741061B2 (ja) * 1987-07-09 1995-05-10 華郎 前田 医療用被覆材
JPH0688885B2 (ja) * 1987-12-26 1994-11-09 品川燃料株式会社 抗菌性粉体を含有する分散体の製造方法
JP2512324B2 (ja) 1988-11-24 1996-07-03 株式会社ジーシーデンタルプロダクツ 歯科用樹脂組成物
US4957817A (en) 1988-11-25 1990-09-18 The Dow Chemical Film, fiber, and microporous membranes of poly(etheretherketone)dissolved in high boiling point polar organic solvents
US5588443A (en) 1989-07-25 1996-12-31 Smith & Nephew Richards, Inc. Zirconium oxide and zirconium nitride coated guide wires
JP2811331B2 (ja) 1989-10-02 1998-10-15 ゼリア新薬工業株式会社 骨形成促進剤
US5192590A (en) 1989-11-03 1993-03-09 Raychem Corporation Coating metal on poly(aryl ether ketone) surfaces
IL96313A (en) 1989-11-14 1995-03-30 Sangi Kk Antibacterial ceramic
JPH03199403A (ja) 1989-12-27 1991-08-30 Chugoku Pearl Hanbai Kk 無菌性手袋
US5256390A (en) 1990-07-03 1993-10-26 Ethyl Corporation Biocidal zeolite particles
US5296238A (en) 1991-02-26 1994-03-22 Toagosei Chemical Industry Co., Inc. Microbicides
US5282847A (en) 1991-02-28 1994-02-01 Medtronic, Inc. Prosthetic vascular grafts with a pleated structure
US5503840A (en) 1991-08-09 1996-04-02 E. I. Du Pont De Nemours And Company Antimicrobial compositions, process for preparing the same and use
US5180585A (en) 1991-08-09 1993-01-19 E. I. Du Pont De Nemours And Company Antimicrobial compositions, process for preparing the same and use
EP0677989B1 (en) 1991-08-09 1998-09-16 E.I. Du Pont De Nemours And Company Antimicrobial compositions, process for preparing the same and use
WO1993007924A1 (en) 1991-10-18 1993-04-29 Spire Corporation Bactericidal coatings for implants
JPH05124919A (ja) 1991-11-05 1993-05-21 Sangi Co Ltd 抗菌性セラミツクス
JPH05230325A (ja) 1992-02-24 1993-09-07 Polyplastics Co 防菌、防カビ性ポリアセタール樹脂組成物
US5681575A (en) 1992-05-19 1997-10-28 Westaim Technologies Inc. Anti-microbial coating for medical devices
US5492763A (en) 1992-06-08 1996-02-20 Spire Corporation Infection resistant medical devices and process
DE69320167T2 (de) 1992-12-25 1999-01-21 Japan Synthetic Rubber Co., Ltd., Tokio/Tokyo Antibakterielle Kunstharzzusammensetzung
US5522904A (en) 1993-10-13 1996-06-04 Hercules Incorporated Composite femoral implant having increased neck strength
US6180606B1 (en) 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
JP3121503B2 (ja) 1994-10-18 2001-01-09 レンゴー株式会社 抗菌剤
JP2860951B2 (ja) 1995-01-12 1999-02-24 株式会社萩原技研 抗菌性ポリマー組成物
US5731087A (en) 1995-06-07 1998-03-24 Union Carbide Chemicals & Plastics Technology Corporation Lubricious coatings containing polymers with vinyl and carboxylic acid moieties
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5756145A (en) 1995-11-08 1998-05-26 Baylor College Of Medicine Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor
DE69632996T2 (de) 1995-12-26 2005-07-21 Toyo Boseki K.K. In organischen Lösungsmitteln lösliche Mucopolysaccharide, antibakterielles antithrombogenes Mittel und medizinisches Material
US6015816A (en) 1996-02-29 2000-01-18 The Research Foundation Of State University Of New York Antimicrobial compositions
US5688561A (en) 1996-04-16 1997-11-18 Kabushiki Kaisha Nippankenkyusho Coating method
AU8681098A (en) 1997-08-01 1999-03-08 Massachusetts Institute Of Technology Three-dimensional polymer matrices
AU8846398A (en) 1997-08-11 1999-03-01 University Of Toronto Innovations Foundation, The Antimicrobial cement compositions
JP3143660B2 (ja) 1997-11-27 2001-03-07 工業技術院長 亜鉛含有リン酸三カルシウムからなるセラミックス及び亜鉛徐放性生体用セラミックス
EP1100558A1 (en) 1998-07-24 2001-05-23 Pharmacal Biotechnologies, Inc. Osseous tissue reconstruction system and method
US6248342B1 (en) 1998-09-29 2001-06-19 Agion Technologies, Llc Antibiotic high-pressure laminates
US6296863B1 (en) * 1998-11-23 2001-10-02 Agion Technologies, Llc Antimicrobial fabric and medical graft of the fabric
US6436422B1 (en) 1998-11-23 2002-08-20 Agion Technologies L.L.C. Antibiotic hydrophilic polymer coating
US6585767B1 (en) 1998-11-23 2003-07-01 Agion Technologies, Inc. Antimicrobial suturing ring for heart valve
US6582715B1 (en) * 1999-04-27 2003-06-24 Agion Technologies, Inc. Antimicrobial orthopedic implants
US6723428B1 (en) 1999-05-27 2004-04-20 Foss Manufacturing Co., Inc. Anti-microbial fiber and fibrous products
EP1066825A1 (en) 1999-06-17 2001-01-10 The Procter & Gamble Company An anti-microbial body care product
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
US6267590B1 (en) 1999-11-24 2001-07-31 Agion Technologies, Llc Antimicrobial dental products
US8017369B2 (en) 2000-02-23 2011-09-13 The Trustees Of The University Of Pennsylvania System and method of up-regulating bone morphogenetic proteins (BMP) gene expression in bone cells via the application of fields generated by specific and selective electric and electromagnetic signals
DE10037850A1 (de) 2000-08-01 2002-02-21 Herbert P Jennissen Verfahren zur Herstellung bioaktiver Implantatoberflächen
US6866859B2 (en) 2000-08-30 2005-03-15 Biocoat Incorporated Bi-laminar, hyaluronan coatings with silver-based anti-microbial properties
DE10043151A1 (de) 2000-08-31 2002-03-28 Peter Steinruecke Knochenzement mit antimikrobieller Wirksamkeit
DE10055465A1 (de) 2000-11-09 2002-05-23 Blz Gmbh Knochenersatzwerkstoff und Verfahren zur Herstellung eines Knochenersatz-Implantats
DE20020649U1 (de) 2000-12-06 2002-04-11 stryker Trauma GmbH, 24232 Schönkirchen Vorrichtung für den chirurgischen oder therapeutischen Gebrauch, insbesondere Implantate und chirurgische Instrumente sowie deren Zubehör
CN1302707C (zh) 2001-01-04 2007-03-07 拜奥特罗尔股份有限公司 抗微生物组合物
JP2004536621A (ja) * 2001-01-30 2004-12-09 イソティス エス．エー． 医療用デバイスに生物活性コーティングを施与する方法
ATE429879T1 (de) 2001-02-27 2009-05-15 Coligne Ag Medizinisches implantat
CA2468780A1 (en) 2001-12-03 2003-06-12 C.R. Bard, Inc. Microbe-resistant medical device, microbe-resistant polymeric coating and methods for producing same
US7357949B2 (en) * 2001-12-21 2008-04-15 Agion Technologies Inc. Encapsulated inorganic antimicrobial additive for controlled release
DK1492579T3 (da) 2002-04-09 2009-01-19 Numat As Medicinske proteseindretninger med forbedret bioforligelighed
DE10243132B4 (de) 2002-09-17 2006-09-14 Biocer Entwicklungs Gmbh Antiinfektiöse, biokompatible Titanoxid-Beschichtungen für Implantate sowie Verfahren zu deren Herstellung
CA2501822C (en) 2002-10-08 2012-02-21 Osteotech, Inc. Coupling agents for orthopedic biomaterials
FR2848856B1 (fr) 2002-12-24 2007-05-25 Cadorel Catherine Materiau a usage medical ou veterinaire, son procede d'obtention et ses applications
US20060259020A1 (en) * 2003-09-17 2006-11-16 Minnesota Scientific, Inc. Bacteria resistant coating for surgical instrument
WO2005027722A2 (en) 2003-09-17 2005-03-31 Minnesota Scientific, Inc. Bacteria resistant coating for surgical instrument
US20050149196A1 (en) 2004-01-07 2005-07-07 St. Francis Medical Technologies, Inc. Artificial spinal disk replacement device with rotation limiter and lateral approach implantation method
WO2006096167A1 (en) 2004-03-03 2006-09-14 Melnick, Benedetta, D. Minimally-invasive method for performing spinal fusion and bone graft capsule for facilitating the same
WO2006024253A1 (de) * 2004-09-03 2006-03-09 Weinmann Geräte für Medizin GmbH & Co. KG Kunststoffe für medizintechnische geräte
US20060069438A1 (en) 2004-09-29 2006-03-30 Zucherman James F Multi-piece artificial spinal disk replacement device with multi-segmented support plates
US7670384B2 (en) 2004-10-14 2010-03-02 Biomet Manufacturing Corp. Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone
CA2590386A1 (en) 2004-12-30 2006-07-06 Cinvention Ag Combination comprising an agent providing a signal, an implant material and a drug
CN101151039A (zh) 2005-04-04 2008-03-26 加利福尼亚大学董事会 用于止血调节和伤口愈合治疗的无机材料
US7662186B2 (en) 2005-05-06 2010-02-16 Titan Spine, Llc Anterior interbody spinal implant
AU2006249942B2 (en) 2005-05-26 2011-07-07 Zimmer Dental, Inc. Prosthetic dental device
CA2612446A1 (en) 2005-07-01 2007-01-11 Cinvention Ag Process for the production of porous reticulated composite materials
EP1922052B1 (en) 2005-08-08 2010-11-03 Angstrom Medica, Inc. Cement products and methods of making and using the same
JP2007091501A (ja) 2005-09-27 2007-04-12 Sinanen Zeomic Co Ltd 抗菌性ゼオライト及び抗菌性樹脂組成物
WO2007056671A1 (en) 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
EP1813292A1 (en) 2006-01-25 2007-08-01 Inion Oy Surgical implant and manufacturing method
GB0601687D0 (en) 2006-01-27 2006-03-08 Smith & Nephew Antimicrobial materials
PT2012839E (pt) 2006-04-07 2012-04-18 Bactiguard Ab Substratos anti-microbianos novos e utilizações dos mesmos
US7879027B2 (en) 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US7661430B2 (en) 2006-05-19 2010-02-16 Richard Mason Antimicrobial dental appliances including mouthguards and mouthpieces
US20080033572A1 (en) 2006-08-03 2008-02-07 Ebi L.P. Bone graft composites and methods of treating bone defects
US8968797B2 (en) 2006-09-25 2015-03-03 Orthovita, Inc. Bioactive load-bearing composites
FR2906147B1 (fr) 2006-09-26 2012-11-02 Biomatlante Procede de sablage de polymeres biocompatibles
WO2008048266A1 (en) 2006-10-20 2008-04-24 Ticona Llc Polyether ether ketone/ polyphenylene sulfide blend
CN101234304A (zh) * 2007-02-02 2008-08-06 中国科学院化学研究所 一种聚醚醚酮多孔膜及其制备方法
FR2912740B1 (fr) 2007-02-21 2012-02-17 Cougoulic Catherine Cadorel Materiau composite poreux a usage biomedical
WO2008104964A2 (en) 2007-02-26 2008-09-04 University Of Limerick A synthetic bone graft
WO2008122594A2 (en) 2007-04-05 2008-10-16 Cinvention Ag Partially biodegradable therapeutic implant for bone and cartilage repair
US20090012612A1 (en) 2007-04-10 2009-01-08 David White Devices and methods for push-delivery of implants
FR2915088B1 (fr) 2007-04-18 2010-03-12 Cadorel Catherine Implant endo-osseux composite a accrochage mecanique optimise et procede de fabrication d'un tel implant.
WO2008150867A2 (en) 2007-05-29 2008-12-11 Innova Materials, Llc Surfaces having particles and related methods
JP5372782B2 (ja) 2008-01-28 2013-12-18 日本特殊陶業株式会社 生体インプラント及びその製造方法
CN101952341B (zh) * 2008-02-01 2016-03-23 辛西斯有限责任公司 多孔的生物相容性聚合物材料和方法
US8014131B2 (en) * 2008-02-05 2011-09-06 Siemens Industry, Inc. Riser bus bar positioning block
US8545222B2 (en) 2008-10-21 2013-10-01 Chan Qian Wang Method of dental implant restoration
JP2012518497A (ja) 2009-02-25 2012-08-16 オーソボンド コーポレーション 抗感染性官能基表面とその製造方法
US20120141599A1 (en) 2009-04-01 2012-06-07 Difusion Technologies, Inc. Regulation Of Bone Growth Using Zeolite In Combination With Bone Graft Substitutes
DE102009023459B4 (de) 2009-06-02 2017-08-31 Aap Implantate Ag Osteosynthese mit Nanosilber
RU2526168C2 (ru) * 2009-12-11 2014-08-20 Дифьюжн Текнолоджиз, Инк. Способ получения противомикробных имплантатов из полиэфирэфиркетона
EP2338532B1 (en) 2009-12-23 2018-01-10 Fundacion Inasmet Porous PEEK article as an implant
EP2571542B1 (en) 2010-05-07 2018-06-20 Difusion Technologies Inc. Medical implants with increased hydrophilicity
WO2014152649A1 (en) 2013-03-15 2014-09-25 Difusion Technologies, Inc. Enhanced efficacy self-sterilizing orthopedic implants

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EP2504041A2 (en) 2012-10-03
CN102802685B (zh) 2015-05-27
IN2012DN04965A (OSRAM) 2015-09-25
US20120315340A1 (en) 2012-12-13
US9492584B2 (en) 2016-11-15
EP2504041A4 (en) 2013-06-19
CN102802685A (zh) 2012-11-28
RU2552939C2 (ru) 2015-06-10
BR112012012603A2 (pt) 2017-11-21
RU2012126078A (ru) 2013-12-27
WO2011066391A3 (en) 2011-10-06
US20200338237A1 (en) 2020-10-29
CN104941004B (zh) 2018-09-14
US20170021061A1 (en) 2017-01-26
CN104941004A (zh) 2015-09-30
EP2504041B1 (en) 2017-04-12
WO2011066391A2 (en) 2011-06-03

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