IN2012DN04965A - - Google Patents
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- Publication number
- IN2012DN04965A IN2012DN04965A IN4965DEN2012A IN2012DN04965A IN 2012DN04965 A IN2012DN04965 A IN 2012DN04965A IN 4965DEN2012 A IN4965DEN2012 A IN 4965DEN2012A IN 2012DN04965 A IN2012DN04965 A IN 2012DN04965A
- Authority
- IN
- India
- Prior art keywords
- certain embodiments
- zeolites
- post
- cations
- disclosed
- Prior art date
Links
- 239000010457 zeolite Substances 0.000 abstract 4
- 230000000845 anti-microbial effect Effects 0.000 abstract 3
- 150000001768 cations Chemical class 0.000 abstract 3
- 229910021536 Zeolite Inorganic materials 0.000 abstract 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 239000000919 ceramic Substances 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 229920001169 thermoplastic Polymers 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/443—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Molecular Biology (AREA)
- Ceramic Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Prostheses (AREA)
- Treatment Of Water By Ion Exchange (AREA)
- Dental Preparations (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polymers & Plastics (AREA)
Abstract
Methods of post-loading ceramic particles with antimicrobial metal cations are disclosed. In certain embodiments, the post-loaded particles are zeolites, wherein the zeolites have been incorporated into a resin and the combination is used as an implantable device. In certain embodiments, the polymer is a thermoplastic polymer such as polyaryletheretherketone (PEEK). In certain embodiments, the source of antimicrobial activi ty includes ion-exchangeable cations contained in a zeolite. In certain embodiments, disclosed are methods of imparting antimicrobial activity to devices by controlling the delivery of certain cations through ion-exchange via a zeolite incorporated in the device.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26428909P | 2009-11-25 | 2009-11-25 | |
| US30063110P | 2010-02-02 | 2010-02-02 | |
| PCT/US2010/058009 WO2011066391A2 (en) | 2009-11-25 | 2010-11-24 | Post-charging of zeolite doped plastics with antimicrobial metal ions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN04965A true IN2012DN04965A (en) | 2015-09-25 |
Family
ID=44067221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4965DEN2012 IN2012DN04965A (en) | 2009-11-25 | 2010-11-24 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US9492584B2 (en) |
| EP (1) | EP2504041B1 (en) |
| CN (2) | CN104941004B (en) |
| BR (1) | BR112012012603B1 (en) |
| IN (1) | IN2012DN04965A (en) |
| RU (1) | RU2552939C2 (en) |
| WO (1) | WO2011066391A2 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012016027B1 (en) | 2009-12-11 | 2019-01-15 | Difusion Technologies, Inc. | production method of polyetheretherketone antimicrobial implants |
| CA2795836C (en) | 2010-05-07 | 2015-11-17 | Difusion Technologies, Inc. | Medical implant comprising a thermoplastic resin having aluminosilicate particles incorporated therein |
| WO2014152653A1 (en) * | 2013-03-14 | 2014-09-25 | Difusion Technologies, Inc. | Self sterilizing orthopedic implants |
| WO2014152649A1 (en) * | 2013-03-15 | 2014-09-25 | Difusion Technologies, Inc. | Enhanced efficacy self-sterilizing orthopedic implants |
| WO2018148453A1 (en) * | 2017-02-09 | 2018-08-16 | Femasys, Inc. | Methods and compositions comprising biodegradable cyanoacrylates |
| US11766339B1 (en) | 2017-10-24 | 2023-09-26 | Omnia Medical, LLC | Multi-material multi-component spinal implant |
| US10736752B1 (en) | 2017-10-24 | 2020-08-11 | Omnia Medical, LLC | Multi-material multi-component spinal implant |
| KR20200118087A (en) * | 2018-02-02 | 2020-10-14 | 에보니크 오퍼레이션즈 게엠베하 | Functional oblique polymer knee implant and fabrication for improved fixation, wear resistance, and mechanical properties |
| FR3084351B1 (en) | 2018-07-26 | 2021-04-02 | Enercat | ZEOLITH DOPED BY A CATION OF TRANSITIONAL METAL AND MODIFIED BY A QUATERNARY AMMONIUM, PREPARATION AND USE |
| US11439726B2 (en) | 2018-12-03 | 2022-09-13 | Osseomimetic, LLC | Surgical implants |
| US20210402052A1 (en) | 2020-06-30 | 2021-12-30 | Difusion, Inc. | Medical Implants And Methods Of Manufacture |
| CN112608230A (en) * | 2020-11-17 | 2021-04-06 | 银金达(上海)新材料有限公司 | Low-metal-ion PETG material and application thereof |
| US20250242085A1 (en) * | 2022-04-14 | 2025-07-31 | Difusion, Inc. | Surgical implants with enhanced osseointegration and methods of manufacture |
Family Cites Families (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4088737A (en) | 1976-11-02 | 1978-05-09 | The United States Of America As Represented By The United States Department Of Energy | Dry method for recycling iodine-loaded silver zeolite |
| EP0048246B1 (en) | 1980-03-27 | 1986-05-28 | National Research Development Corporation | Antimicrobial surgical implants |
| DE3228849C2 (en) | 1982-08-02 | 1989-06-08 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Medical device to be inserted into the body |
| EP0124536A4 (en) | 1982-11-05 | 1985-06-06 | Baxter Travenol Lab | Antimicrobial compositions. |
| JPS59133235A (en) * | 1983-01-21 | 1984-07-31 | Kanebo Ltd | Zeolite particle-containing polymer and its production |
| US4596574A (en) | 1984-05-14 | 1986-06-24 | The Regents Of The University Of California | Biodegradable porous ceramic delivery system for bone morphogenetic protein |
| US4612337A (en) | 1985-05-30 | 1986-09-16 | The Trustees Of Columbia University In The City Of New York | Method for preparing infection-resistant materials |
| GB2190383B (en) | 1986-04-08 | 1990-03-28 | Dentsply Ltd | Glass/poly (carboxylic acid)cement compositions |
| JPS6323960A (en) | 1986-07-16 | 1988-02-01 | Zenji Hagiwara | High molecular material containing amorphous aluminosilicate particle and production thereof |
| US4938958A (en) | 1986-12-05 | 1990-07-03 | Shinagawa Fuel Co., Ltd. | Antibiotic zeolite |
| US4775586A (en) | 1987-02-17 | 1988-10-04 | Armstrong World Industries, Inc. | Paper, paper products, films composites and other silicate-polymer, construction materials |
| JPS63265958A (en) * | 1987-04-22 | 1988-11-02 | Shinagawa Nenryo Kk | Antibacterial resin composition |
| JPH0618899B2 (en) | 1987-06-30 | 1994-03-16 | 品川燃料株式会社 | Film containing antibacterial zeolite |
| JPH0741061B2 (en) | 1987-07-09 | 1995-05-10 | 華郎 前田 | Medical dressing |
| JPS6415056A (en) | 1987-07-09 | 1989-01-19 | Hanarou Maeda | Body indwelling tube |
| JPH0688885B2 (en) * | 1987-12-26 | 1994-11-09 | 品川燃料株式会社 | Method for producing dispersion containing antibacterial powder |
| JP2512324B2 (en) | 1988-11-24 | 1996-07-03 | 株式会社ジーシーデンタルプロダクツ | Dental resin composition |
| US4957817A (en) | 1988-11-25 | 1990-09-18 | The Dow Chemical | Film, fiber, and microporous membranes of poly(etheretherketone)dissolved in high boiling point polar organic solvents |
| US5632779A (en) | 1989-07-25 | 1997-05-27 | Smith & Nephew, Inc. | Zirconium oxide and zirconium nitride coated vascular grafts |
| JP2811331B2 (en) | 1989-10-02 | 1998-10-15 | ゼリア新薬工業株式会社 | Bone formation promoter |
| US5192590A (en) | 1989-11-03 | 1993-03-09 | Raychem Corporation | Coating metal on poly(aryl ether ketone) surfaces |
| IL96313A (en) | 1989-11-14 | 1995-03-30 | Sangi Kk | Antibacterial ceramic material |
| JPH03199403A (en) | 1989-12-27 | 1991-08-30 | Chugoku Pearl Hanbai Kk | sterile gloves |
| US5256390A (en) | 1990-07-03 | 1993-10-26 | Ethyl Corporation | Biocidal zeolite particles |
| US5296238A (en) | 1991-02-26 | 1994-03-22 | Toagosei Chemical Industry Co., Inc. | Microbicides |
| US5282847A (en) | 1991-02-28 | 1994-02-01 | Medtronic, Inc. | Prosthetic vascular grafts with a pleated structure |
| EP0677989B1 (en) | 1991-08-09 | 1998-09-16 | E.I. Du Pont De Nemours And Company | Antimicrobial compositions, process for preparing the same and use |
| US5503840A (en) | 1991-08-09 | 1996-04-02 | E. I. Du Pont De Nemours And Company | Antimicrobial compositions, process for preparing the same and use |
| US5180585A (en) | 1991-08-09 | 1993-01-19 | E. I. Du Pont De Nemours And Company | Antimicrobial compositions, process for preparing the same and use |
| WO1993007924A1 (en) | 1991-10-18 | 1993-04-29 | Spire Corporation | Bactericidal coatings for implants |
| JPH05124919A (en) | 1991-11-05 | 1993-05-21 | Sangi Co Ltd | Antibacterial ceramics |
| JPH05230325A (en) | 1992-02-24 | 1993-09-07 | Polyplastics Co | Antibacterial, antifungal polyacetal resin composition |
| US5681575A (en) | 1992-05-19 | 1997-10-28 | Westaim Technologies Inc. | Anti-microbial coating for medical devices |
| US5492763A (en) | 1992-06-08 | 1996-02-20 | Spire Corporation | Infection resistant medical devices and process |
| DE69320167T2 (en) | 1992-12-25 | 1999-01-21 | Japan Synthetic Rubber Co., Ltd., Tokio/Tokyo | Antibacterial resin composition |
| US5522904A (en) | 1993-10-13 | 1996-06-04 | Hercules Incorporated | Composite femoral implant having increased neck strength |
| US6180606B1 (en) | 1994-09-28 | 2001-01-30 | Gensci Orthobiologics, Inc. | Compositions with enhanced osteogenic potential, methods for making the same and uses thereof |
| JP3121503B2 (en) | 1994-10-18 | 2001-01-09 | レンゴー株式会社 | Antibacterial agent |
| JP2860951B2 (en) | 1995-01-12 | 1999-02-24 | 株式会社萩原技研 | Antimicrobial polymer composition |
| US5731087A (en) | 1995-06-07 | 1998-03-24 | Union Carbide Chemicals & Plastics Technology Corporation | Lubricious coatings containing polymers with vinyl and carboxylic acid moieties |
| US5609629A (en) | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
| US5756145A (en) | 1995-11-08 | 1998-05-26 | Baylor College Of Medicine | Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor |
| DE69632996T2 (en) | 1995-12-26 | 2005-07-21 | Toyo Boseki K.K. | Organic solvent-soluble mucopolysaccharides, antibacterial antithrombogenic agent and medical material |
| US6015816A (en) | 1996-02-29 | 2000-01-18 | The Research Foundation Of State University Of New York | Antimicrobial compositions |
| US5688561A (en) | 1996-04-16 | 1997-11-18 | Kabushiki Kaisha Nippankenkyusho | Coating method |
| WO1999009149A1 (en) | 1997-08-01 | 1999-02-25 | Massachusetts Institute Of Technology | Three-dimensional polymer matrices |
| AU8846398A (en) | 1997-08-11 | 1999-03-01 | University Of Toronto Innovations Foundation, The | Antimicrobial cement compositions |
| JP3143660B2 (en) | 1997-11-27 | 2001-03-07 | 工業技術院長 | Ceramics comprising zinc-containing tricalcium phosphate and sustained-release zinc bioceramics |
| AU5390699A (en) | 1998-07-24 | 2000-02-14 | Pharmacal Biotechnologies, Inc. | Osseous tissue reconstruction system and method |
| US6248342B1 (en) | 1998-09-29 | 2001-06-19 | Agion Technologies, Llc | Antibiotic high-pressure laminates |
| US6436422B1 (en) | 1998-11-23 | 2002-08-20 | Agion Technologies L.L.C. | Antibiotic hydrophilic polymer coating |
| US6585767B1 (en) | 1998-11-23 | 2003-07-01 | Agion Technologies, Inc. | Antimicrobial suturing ring for heart valve |
| US6296863B1 (en) | 1998-11-23 | 2001-10-02 | Agion Technologies, Llc | Antimicrobial fabric and medical graft of the fabric |
| US6582715B1 (en) * | 1999-04-27 | 2003-06-24 | Agion Technologies, Inc. | Antimicrobial orthopedic implants |
| US6723428B1 (en) | 1999-05-27 | 2004-04-20 | Foss Manufacturing Co., Inc. | Anti-microbial fiber and fibrous products |
| EP1066825A1 (en) | 1999-06-17 | 2001-01-10 | The Procter & Gamble Company | An anti-microbial body care product |
| US8323341B2 (en) | 2007-09-07 | 2012-12-04 | Intrinsic Therapeutics, Inc. | Impaction grafting for vertebral fusion |
| US6267590B1 (en) | 1999-11-24 | 2001-07-31 | Agion Technologies, Llc | Antimicrobial dental products |
| DE10037850A1 (en) | 2000-08-01 | 2002-02-21 | Herbert P Jennissen | Process for the production of bioactive implant surfaces |
| US6866859B2 (en) | 2000-08-30 | 2005-03-15 | Biocoat Incorporated | Bi-laminar, hyaluronan coatings with silver-based anti-microbial properties |
| DE10043151A1 (en) | 2000-08-31 | 2002-03-28 | Peter Steinruecke | Bone cement with antimicrobial effectiveness |
| DE10055465A1 (en) | 2000-11-09 | 2002-05-23 | Blz Gmbh | Material useful for making bone replacement implants comprises nonmetallic inorganic filler particles embedded in a laser-sinterable biocompatible polymer matrix |
| DE20020649U1 (en) | 2000-12-06 | 2002-04-11 | stryker Trauma GmbH, 24232 Schönkirchen | Device for surgical or therapeutic use, in particular implants and surgical instruments and their accessories |
| CN1961666B (en) | 2001-01-04 | 2011-06-22 | 拜奥特罗尔股份有限公司 | Anti-microbial composition |
| JP2004536621A (en) | 2001-01-30 | 2004-12-09 | イソティス エス.エー. | Method of applying a bioactive coating to a medical device |
| DE60138521D1 (en) | 2001-02-27 | 2009-06-10 | Co Ligne Ag | Medical implant |
| JP2005511144A (en) | 2001-12-03 | 2005-04-28 | シー・アール・バード・インク | Microbial-resistant medical device, microbial-resistant polymer coating and production method thereof |
| US7357949B2 (en) * | 2001-12-21 | 2008-04-15 | Agion Technologies Inc. | Encapsulated inorganic antimicrobial additive for controlled release |
| RU2313370C2 (en) | 2002-04-09 | 2007-12-27 | Астра Тек АБ | Medicinal prostheses of improved biological compatibility |
| DE10243132B4 (en) | 2002-09-17 | 2006-09-14 | Biocer Entwicklungs Gmbh | Anti-infective, biocompatible titanium oxide coatings for implants and methods of making them |
| CA2501822C (en) | 2002-10-08 | 2012-02-21 | Osteotech, Inc. | Coupling agents for orthopedic biomaterials |
| FR2848856B1 (en) | 2002-12-24 | 2007-05-25 | Cadorel Catherine | MATERIAL FOR MEDICAL OR VETERINARY USE, PROCESS FOR OBTAINING SAME AND APPLICATIONS THEREOF |
| US20060259020A1 (en) * | 2003-09-17 | 2006-11-16 | Minnesota Scientific, Inc. | Bacteria resistant coating for surgical instrument |
| WO2005027722A2 (en) | 2003-09-17 | 2005-03-31 | Minnesota Scientific, Inc. | Bacteria resistant coating for surgical instrument |
| US20050149196A1 (en) | 2004-01-07 | 2005-07-07 | St. Francis Medical Technologies, Inc. | Artificial spinal disk replacement device with rotation limiter and lateral approach implantation method |
| CA2553199C (en) | 2004-01-12 | 2014-03-25 | The Trustees Of The University Of Pennsylvania | System for up-regulating bone morphogenetic protein (bmp) gene expression in bone cells via the application of fields generated by specific electric and electromagnetic signals |
| WO2006096167A1 (en) | 2004-03-03 | 2006-09-14 | Melnick, Benedetta, D. | Minimally-invasive method for performing spinal fusion and bone graft capsule for facilitating the same |
| US9625065B2 (en) * | 2004-09-03 | 2017-04-18 | Loewenstein Medical Technology S.A. | Plastics for medical technical devices |
| US20060069438A1 (en) | 2004-09-29 | 2006-03-30 | Zucherman James F | Multi-piece artificial spinal disk replacement device with multi-segmented support plates |
| US7670384B2 (en) | 2004-10-14 | 2010-03-02 | Biomet Manufacturing Corp. | Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone |
| EA011594B1 (en) | 2004-12-30 | 2009-04-28 | Синвеншен Аг | Combination comprising an agent providing a signal, an implant material and a drug |
| US7858123B2 (en) | 2005-04-04 | 2010-12-28 | The Regents Of The University Of California | Inorganic materials for hemostatic modulation and therapeutic wound healing |
| US7662186B2 (en) | 2005-05-06 | 2010-02-16 | Titan Spine, Llc | Anterior interbody spinal implant |
| EP1909685A2 (en) | 2005-05-26 | 2008-04-16 | Zimmer Dental Inc. | Prosthetic dental device |
| CA2612446A1 (en) | 2005-07-01 | 2007-01-11 | Cinvention Ag | Process for the production of porous reticulated composite materials |
| WO2007019461A2 (en) | 2005-08-08 | 2007-02-15 | Angstrom Medica, Inc. | Cement products and methods of making and using the same |
| JP2007091501A (en) | 2005-09-27 | 2007-04-12 | Sinanen Zeomic Co Ltd | Antibacterial zeolite and antibacterial resin composition |
| WO2007056671A1 (en) | 2005-11-02 | 2007-05-18 | Osteotech, Inc. | Hemostatic bone graft |
| EP1813292A1 (en) | 2006-01-25 | 2007-08-01 | Inion Oy | Surgical implant and manufacturing method |
| GB0601687D0 (en) | 2006-01-27 | 2006-03-08 | Smith & Nephew | Antimicrobial materials |
| ES2379989T3 (en) | 2006-04-07 | 2012-05-07 | Bactiguard Ab | Novel antimicrobial substrates and their uses |
| US7879027B2 (en) | 2006-04-24 | 2011-02-01 | Warsaw Orthopedic, Inc. | Controlled release devices for fusion of osteal structures |
| US7661430B2 (en) | 2006-05-19 | 2010-02-16 | Richard Mason | Antimicrobial dental appliances including mouthguards and mouthpieces |
| US20080033572A1 (en) | 2006-08-03 | 2008-02-07 | Ebi L.P. | Bone graft composites and methods of treating bone defects |
| WO2008039488A2 (en) | 2006-09-25 | 2008-04-03 | Vita Special Purpose Corporation | Bioactive load-bearing composites |
| FR2906147B1 (en) | 2006-09-26 | 2012-11-02 | Biomatlante | METHOD FOR SANDING BIOCOMPATIBLE POLYMERS |
| WO2008048266A1 (en) | 2006-10-20 | 2008-04-24 | Ticona Llc | Polyether ether ketone/ polyphenylene sulfide blend |
| CN101234304A (en) * | 2007-02-02 | 2008-08-06 | 中国科学院化学研究所 | A kind of polyetheretherketone porous membrane and preparation method thereof |
| FR2912740B1 (en) | 2007-02-21 | 2012-02-17 | Cougoulic Catherine Cadorel | POROUS COMPOSITE MATERIAL FOR BIOMEDICAL USE |
| WO2008104964A2 (en) | 2007-02-26 | 2008-09-04 | University Of Limerick | A synthetic bone graft |
| WO2008122594A2 (en) | 2007-04-05 | 2008-10-16 | Cinvention Ag | Partially biodegradable therapeutic implant for bone and cartilage repair |
| US20090012612A1 (en) | 2007-04-10 | 2009-01-08 | David White | Devices and methods for push-delivery of implants |
| FR2915088B1 (en) | 2007-04-18 | 2010-03-12 | Cadorel Catherine | COMPOSITE ENDO-BONE COMPOSITE IMPLANT WITH OPTIMIZED MECHANICAL ATTACHMENT AND METHOD FOR MANUFACTURING SUCH IMPLANT |
| JP6017110B2 (en) * | 2007-05-29 | 2016-11-09 | ティーピーケイ ホールディング カンパニー リミテッド | Particle-containing surfaces and related methods |
| US9931438B2 (en) | 2008-01-28 | 2018-04-03 | Ngk Spark Plug Co., Ltd. | Article with foamed surface, implant and method of producing the same |
| EP2238192B1 (en) * | 2008-02-01 | 2017-03-01 | Synthes GmbH | Porous biocompatible polymer material and methods |
| US8014131B2 (en) * | 2008-02-05 | 2011-09-06 | Siemens Industry, Inc. | Riser bus bar positioning block |
| US8545222B2 (en) | 2008-10-21 | 2013-10-01 | Chan Qian Wang | Method of dental implant restoration |
| KR20170121209A (en) | 2009-02-25 | 2017-11-01 | 오소본드 코포레이션 | Anti-infective funtionalized surfaces and methods of making same |
| CN102387782B (en) | 2009-04-01 | 2013-10-30 | 扩散技术公司 | Regulation of bone growth using zeolite in combination with bone graft substitutes |
| DE102009023459B4 (en) | 2009-06-02 | 2017-08-31 | Aap Implantate Ag | Osteosynthesis with nanosilver |
| BR112012016027B1 (en) | 2009-12-11 | 2019-01-15 | Difusion Technologies, Inc. | production method of polyetheretherketone antimicrobial implants |
| ES2664944T3 (en) | 2009-12-23 | 2018-04-24 | Fundacion Inasmet | Porous PEEK article as an implant |
| CA2795836C (en) | 2010-05-07 | 2015-11-17 | Difusion Technologies, Inc. | Medical implant comprising a thermoplastic resin having aluminosilicate particles incorporated therein |
| WO2014152649A1 (en) | 2013-03-15 | 2014-09-25 | Difusion Technologies, Inc. | Enhanced efficacy self-sterilizing orthopedic implants |
-
2010
- 2010-11-24 IN IN4965DEN2012 patent/IN2012DN04965A/en unknown
- 2010-11-24 EP EP10833925.0A patent/EP2504041B1/en active Active
- 2010-11-24 US US13/511,176 patent/US9492584B2/en active Active
- 2010-11-24 CN CN201510165624.3A patent/CN104941004B/en active Active
- 2010-11-24 BR BR112012012603-2A patent/BR112012012603B1/en not_active IP Right Cessation
- 2010-11-24 RU RU2012126078/15A patent/RU2552939C2/en active
- 2010-11-24 WO PCT/US2010/058009 patent/WO2011066391A2/en active Application Filing
- 2010-11-24 CN CN201080062338.XA patent/CN102802685B/en active Active
-
2016
- 2016-10-07 US US15/287,845 patent/US20170021061A1/en not_active Abandoned
-
2020
- 2020-07-08 US US16/923,486 patent/US20200338237A1/en not_active Abandoned
- 2020-07-08 US US16/923,495 patent/US20200338238A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011066391A3 (en) | 2011-10-06 |
| CN104941004A (en) | 2015-09-30 |
| US20200338237A1 (en) | 2020-10-29 |
| RU2012126078A (en) | 2013-12-27 |
| CN102802685A (en) | 2012-11-28 |
| EP2504041A2 (en) | 2012-10-03 |
| EP2504041B1 (en) | 2017-04-12 |
| US20170021061A1 (en) | 2017-01-26 |
| WO2011066391A2 (en) | 2011-06-03 |
| BR112012012603A2 (en) | 2017-11-21 |
| BR112012012603B1 (en) | 2019-03-19 |
| CN102802685B (en) | 2015-05-27 |
| RU2552939C2 (en) | 2015-06-10 |
| CN104941004B (en) | 2018-09-14 |
| US9492584B2 (en) | 2016-11-15 |
| EP2504041A4 (en) | 2013-06-19 |
| US20120315340A1 (en) | 2012-12-13 |
| US20200338238A1 (en) | 2020-10-29 |
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