BR0317696A - Composição para branqueamento - Google Patents

Composição para branqueamento

Info

Publication number
BR0317696A
BR0317696A BR0317696-7A BR0317696A BR0317696A BR 0317696 A BR0317696 A BR 0317696A BR 0317696 A BR0317696 A BR 0317696A BR 0317696 A BR0317696 A BR 0317696A
Authority
BR
Brazil
Prior art keywords
bleaching composition
salt
derivative
composition
cysteine
Prior art date
Application number
BR0317696-7A
Other languages
English (en)
Other versions
BRPI0317696B1 (pt
BRPI0317696B8 (pt
Inventor
Yoshinobu Morimoto
Asami Watake
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32708479&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0317696(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of BR0317696A publication Critical patent/BR0317696A/pt
Publication of BRPI0317696B1 publication Critical patent/BRPI0317696B1/pt
Publication of BRPI0317696B8 publication Critical patent/BRPI0317696B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"COMPOSIçãO PARA BRANQUEAMENTO". Composição compreendendo ácido tranexâmico ou seu sal (i) e L-cisteína ou seu derivado ou seu sal (ii), opcionalmente em conjunto com ácida L-ascórbico ou seu derivado ou seu sal (iii).
BRPI0317696A 2002-12-27 2003-12-26 composição para branqueamento BRPI0317696B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002381304 2002-12-27
PCT/JP2003/017050 WO2004060364A1 (ja) 2002-12-27 2003-12-26 美白用組成物

Publications (3)

Publication Number Publication Date
BR0317696A true BR0317696A (pt) 2005-11-22
BRPI0317696B1 BRPI0317696B1 (pt) 2016-11-08
BRPI0317696B8 BRPI0317696B8 (pt) 2021-05-25

Family

ID=32708479

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0317696A BRPI0317696B8 (pt) 2002-12-27 2003-12-26 composição para branqueamento

Country Status (12)

Country Link
US (1) US20060142382A1 (pt)
EP (1) EP1586315B1 (pt)
JP (1) JP4667875B2 (pt)
KR (3) KR101107754B1 (pt)
CN (1) CN100335048C (pt)
AT (1) ATE464041T1 (pt)
AU (1) AU2003292657A1 (pt)
BR (1) BRPI0317696B8 (pt)
DE (1) DE60332163D1 (pt)
HK (1) HK1084327A1 (pt)
MX (1) MXPA05006924A (pt)
WO (1) WO2004060364A1 (pt)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001342110A (ja) * 2000-06-02 2001-12-11 Ezaki Glico Co Ltd 皮膚外用剤
US20050025825A1 (en) 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
US20090215898A1 (en) 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20050244495A1 (en) 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US8022106B2 (en) 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
JPWO2006003965A1 (ja) * 2004-06-30 2008-04-17 第一三共ヘルスケア株式会社 美白組成物
WO2006023001A1 (en) * 2004-07-30 2006-03-02 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
JP4845363B2 (ja) * 2004-10-01 2011-12-28 ユニチカ株式会社 経口投与組成物及び美白剤
JP5576006B2 (ja) * 2005-01-21 2014-08-20 エスエス製薬株式会社 １日２回服用型経口投与製剤
FI20050453A0 (fi) * 2005-04-29 2005-04-29 Aromtech Ltd Ihonhoitokoostumus
TWI370739B (en) * 2005-12-30 2012-08-21 Ind Tech Res Inst Herbal compositions of inhibiting free radicals
US8980336B2 (en) * 2005-12-30 2015-03-17 Industrial Technology Research Institute Method for inhibiting free radicals
FR2911278B1 (fr) * 2007-01-12 2009-05-01 Limousine D Applic Biolog Dite Procede d'obtention d'un actif cosmetique depigmentant, principe actif obtenu et compositions l'incluant
CN101621987B (zh) * 2007-02-28 2013-08-21 宝洁公司 包含孟加拉榕树植物提取物的个人护理组合物
US20080241084A1 (en) * 2007-03-29 2008-10-02 Shaklee Corporation Compositions and methods for inhibiting melanogenesis
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
US10435356B1 (en) * 2007-09-18 2019-10-08 Thermolife International, Llc Amino acid compositions
US8569369B2 (en) 2007-09-18 2013-10-29 Thermolife International, Llc Amino acid compounds
US10646508B1 (en) 2007-09-18 2020-05-12 Thermolife International, Llc Method of safely administering nitrate dietary supplements and compositions
US10426792B1 (en) 2007-09-18 2019-10-01 Thermolife International, Llc Amino acid compositions
US10426750B1 (en) * 2007-09-18 2019-10-01 Thermolife International, Llc Amino acid supplement formulations
FR2934158B1 (fr) * 2008-07-23 2012-08-17 Yvon Gauthier Composition dermocosmetique, procede de traitement esthetique a partir de la composition, et utilisation de la composition pour eclaircir la pigmentation de la peau.
MX2011001071A (es) * 2008-08-06 2011-04-26 Daiichi Sankyo Healthcare Co Composicion farmaceutica estable que contiene acido tranexamico y acido ascorbico.
CN102137664B (zh) * 2008-09-05 2014-08-06 第一三共健康事业株式会社 具有被边界隔开的有效成分的固体药物制剂
JP5694177B2 (ja) * 2009-10-20 2015-04-01 第一三共ヘルスケア株式会社 変色及び臭いが抑制されたフィルムコーティング錠
CA2786649C (en) * 2010-01-12 2017-09-05 Pola Chemical Industries Inc. Prophylactic or ameliorating agent for pigmentation
CN103025310B (zh) * 2010-05-25 2016-01-27 西姆莱斯有限公司 作为皮肤和/或毛发美白活性物的氨基甲酸环己酯化合物
US8597683B2 (en) 2010-11-30 2013-12-03 Watson Pharmaceuticals, Inc. Modified release tranexamic acid formulation
KR20240036130A (ko) 2011-03-28 2024-03-19 마리 케이 인코포레이티드 식물 추출물을 포함하는 국소 스킨 케어 제형
EP2696865B1 (en) 2011-04-13 2016-12-21 Thermolife International, LLC N-acetyl beta alanine methods of use
CN102698251A (zh) * 2012-06-09 2012-10-03 东莞市照燕生物科技有限公司 一种排毒美白的注射针剂
MX2015013727A (es) * 2013-04-04 2016-02-29 Hyundai Pharm Co Ltd Composicion para preparacion de uso externo con permeabilidad transdermica mejorada.
KR101475609B1 (ko) * 2013-06-12 2014-12-23 중앙대학교 산학협력단 억새꽃 추출물을 유효성분으로 함유하는 피부 미백용 조성물
KR101511252B1 (ko) * 2013-08-06 2015-04-10 주식회사 엘지생활건강 백출추출물과 트라넥삼산을 유효성분으로 포함하는 피부 미백용 조성물
KR101687254B1 (ko) * 2014-06-16 2016-12-16 재단법인 경기과학기술진흥원 피부 미백 효과를 갖는 매듭풀 추출물을 함유하는 화장품 조성물
KR101848887B1 (ko) * 2016-06-29 2018-04-13 에이앤펩주식회사 피부 미백 활성을 가지는 트라넥삼산-펩타이드 및 그 용도
CN106265581B (zh) * 2016-09-30 2020-09-04 上海信谊万象药业股份有限公司 一种氨甲环酸片及其制备方法
KR102042317B1 (ko) * 2017-11-27 2019-11-27 주식회사 씨앤피코스메틱스 피부 미백 및 피부톤 개선 효과가 우수한 화장료 조성물
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches
CN113576933A (zh) * 2021-08-26 2021-11-02 广州环亚化妆品科技有限公司 一种具有美白功效的组合物及其制备方法和应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543443B2 (pt) 1972-12-25 1980-11-06
JPS533538A (en) 1976-06-28 1978-01-13 Sansho Seiyaku Kk Skin bleach cosmetics
JPS54138130A (en) * 1978-04-14 1979-10-26 Kiguchi Yuugen Cosmetics containing amino acid llcysteine as effective constituent
JPS59128320A (ja) 1983-01-08 1984-07-24 Kanebo Ltd 美白化粧料
JPS6056912A (ja) 1983-09-07 1985-04-02 Shiseido Co Ltd 皮膚外用剤
GB8517301D0 (en) * 1985-07-09 1985-08-14 Salim A S M Synergistic biologically active substances
DK406686D0 (da) * 1986-08-26 1986-08-26 Hans Bundgaard Carboxylsyrederivater
JPH04243825A (ja) * 1991-01-25 1992-08-31 Ss Pharmaceut Co Ltd 色素沈着症治療剤
JP3167148B2 (ja) 1991-09-11 2001-05-21 第一製薬株式会社 美白剤
JPH0680564A (ja) 1992-09-03 1994-03-22 Meiji Seika Kaisha Ltd 抗色素沈着治療薬
JPH1192326A (ja) * 1997-09-22 1999-04-06 Shiseido Co Ltd 皮膚外用剤
CA2323364A1 (en) * 1998-03-16 1999-09-23 The Procter & Gamble Company Compositions for regulating skin appearance
JP2000053529A (ja) * 1998-06-05 2000-02-22 Shiseido Co Ltd 皮膚外用剤
EP1002515A1 (en) 1998-06-05 2000-05-24 Shiseido Company Limited Skin compositions for external use
CH694549A5 (de) * 2001-01-16 2005-03-31 Dr Matthias Rath Verwendung einer synergistischen Zusammensetzung, die Ascorbat und Lysin für Zustände enthält zur Behandlung extrazellularer Matrixdegeration.
US7381427B2 (en) * 2001-02-09 2008-06-03 Mickey Miller Seborrheic keratosis treatment
JP4786127B2 (ja) * 2002-07-12 2011-10-05 任康 高田 色素沈着改善治療薬

Also Published As

Publication number Publication date
BRPI0317696B1 (pt) 2016-11-08
DE60332163D1 (de) 2010-05-27
CN1753664A (zh) 2006-03-29
EP1586315A4 (en) 2008-04-16
US20060142382A1 (en) 2006-06-29
KR101107754B1 (ko) 2012-01-20
BRPI0317696B8 (pt) 2021-05-25
MXPA05006924A (es) 2005-12-12
JPWO2004060364A1 (ja) 2006-05-11
ATE464041T1 (de) 2010-04-15
EP1586315A1 (en) 2005-10-19
KR20080022592A (ko) 2008-03-11
KR20080025199A (ko) 2008-03-19
AU2003292657A1 (en) 2004-07-29
HK1084327A1 (en) 2006-07-28
WO2004060364A1 (ja) 2004-07-22
JP4667875B2 (ja) 2011-04-13
EP1586315B1 (en) 2010-04-14
KR20050084492A (ko) 2005-08-26
CN100335048C (zh) 2007-09-05

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: DAIICHI SANKYO CO., LTD. (JP)

Free format text: TRANSFERIDO POR INCORPORACAO DE: DAIICHI PHARMACEUTICAL CO., LTD.

B25A Requested transfer of rights approved

Owner name: DAIICHI SANKYO HEALTHCARE CO., LTD. (JP)

Free format text: TRANSFERIDO DE: DAIICHI SANKYO CO., LTD.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 31/196 , A61K 31/198 , A61K 31/375 , A61K 9/08 , A61K 9/20 , A61K 7/00 , A61K 7/48 , A61P 17/00

Ipc: A61K 31/196 (2006.01), A61K 31/198 (2006.01), A61K

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/11/2016, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/12/2003 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF