BR0312967A - Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocina - Google Patents
Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocinaInfo
- Publication number
- BR0312967A BR0312967A BR0312967-5A BR0312967A BR0312967A BR 0312967 A BR0312967 A BR 0312967A BR 0312967 A BR0312967 A BR 0312967A BR 0312967 A BR0312967 A BR 0312967A
- Authority
- BR
- Brazil
- Prior art keywords
- receptor modulators
- chemokine receptor
- sulfonamide derivatives
- pyrimidyl
- pyrimidyl sulfonamide
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title 1
- 108050000299 Chemokine receptor Proteins 0.000 title 1
- WJJBIYLGJUVNJX-UHFFFAOYSA-N pyrimidine-2-sulfonamide Chemical class NS(=O)(=O)C1=NC=CC=N1 WJJBIYLGJUVNJX-UHFFFAOYSA-N 0.000 title 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- -1 ester compound Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
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- C07D239/69—Benzenesulfonamido-pyrimidines
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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- Reproductive Health (AREA)
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- Oncology (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0217431.6A GB0217431D0 (en) | 2002-07-27 | 2002-07-27 | Novel compounds |
| PCT/GB2003/003175 WO2004011443A1 (en) | 2002-07-27 | 2003-07-23 | Pyrimidyl sulphone amide derivatives as chemokine receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0312967A true BR0312967A (pt) | 2005-06-14 |
Family
ID=9941220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0312967-5A BR0312967A (pt) | 2002-07-27 | 2003-07-23 | Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocina |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US7582644B2 (enExample) |
| EP (1) | EP1527051B1 (enExample) |
| JP (1) | JP4619782B2 (enExample) |
| KR (2) | KR20110033313A (enExample) |
| CN (1) | CN100345829C (enExample) |
| AR (1) | AR040700A1 (enExample) |
| AU (1) | AU2003281684B2 (enExample) |
| BR (1) | BR0312967A (enExample) |
| CA (1) | CA2493785C (enExample) |
| CO (1) | CO5680479A2 (enExample) |
| EG (1) | EG25893A (enExample) |
| ES (1) | ES2392965T3 (enExample) |
| GB (1) | GB0217431D0 (enExample) |
| IL (1) | IL166290A0 (enExample) |
| IS (1) | IS7697A (enExample) |
| MX (1) | MXPA05000960A (enExample) |
| MY (1) | MY139561A (enExample) |
| NO (1) | NO330531B1 (enExample) |
| NZ (1) | NZ537914A (enExample) |
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| BR112012017756A2 (pt) | 2009-12-23 | 2016-04-19 | Ironwood Pharmaceuticals Inc | moduladores crth2 |
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| US20150166591A1 (en) | 2012-05-05 | 2015-06-18 | Ariad Pharmaceuticals, Inc. | Methods and compositions for raf kinase mediated diseases |
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| JP6779992B2 (ja) | 2015-10-09 | 2020-11-04 | アッヴィ・エス・ア・エール・エル | N−スルホニル化ピラゾロ[3,4−b]ピリジン−6−カルボキサミドおよび使用法 |
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