BR0312967A - Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocina - Google Patents

Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocina

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Publication number
BR0312967A
BR0312967A BR0312967-5A BR0312967A BR0312967A BR 0312967 A BR0312967 A BR 0312967A BR 0312967 A BR0312967 A BR 0312967A BR 0312967 A BR0312967 A BR 0312967A
Authority
BR
Brazil
Prior art keywords
receptor modulators
chemokine receptor
sulfonamide derivatives
pyrimidyl
pyrimidyl sulfonamide
Prior art date
Application number
BR0312967-5A
Other languages
English (en)
Inventor
Mark Richard Ebden
Premji Meghani
Colin Bennion
Antony Ronald Cook
Roger Victor Bonnert
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0312967A publication Critical patent/BR0312967A/pt

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

"DERIVADOS DE PIRIMIDIL SULFONAMIDAS COMO MODULADORES DE RECEPTOR DE QUIMIOCINA". A presente invenção refere-se a um composto de fórmula (I) sal, solvato ou éster hidrolisável in vivo farmaceuticamente aceitáveis do mesmo, para o tratamento de asma, rinite alérgica, DPOC, doença inflamatória dos intestinos, síndrome do intestino irritável, osteoartrite, osteoporose, artrite rematóide, psoríase ou câncer.
BR0312967-5A 2002-07-27 2003-07-23 Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocina BR0312967A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0217431.6A GB0217431D0 (en) 2002-07-27 2002-07-27 Novel compounds
PCT/GB2003/003175 WO2004011443A1 (en) 2002-07-27 2003-07-23 Pyrimidyl sulphone amide derivatives as chemokine receptor modulators

Publications (1)

Publication Number Publication Date
BR0312967A true BR0312967A (pt) 2005-06-14

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Application Number Title Priority Date Filing Date
BR0312967-5A BR0312967A (pt) 2002-07-27 2003-07-23 Derivados de pirimidil sulfonamidas como moduladores de receptor de quimiocina

Country Status (26)

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US (2) US7582644B2 (pt)
EP (1) EP1527051B1 (pt)
JP (1) JP4619782B2 (pt)
KR (2) KR101074626B1 (pt)
CN (1) CN100345829C (pt)
AR (1) AR040700A1 (pt)
AU (1) AU2003281684B2 (pt)
BR (1) BR0312967A (pt)
CA (1) CA2493785C (pt)
CO (1) CO5680479A2 (pt)
EG (1) EG25893A (pt)
ES (1) ES2392965T3 (pt)
GB (1) GB0217431D0 (pt)
HK (1) HK1076465A1 (pt)
IL (1) IL166290A0 (pt)
IS (1) IS7697A (pt)
MX (1) MXPA05000960A (pt)
MY (1) MY139561A (pt)
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