TWI340038B - Pyrimidyl sulphone amide derivatives as chemokine receptor modulators - Google Patents
Pyrimidyl sulphone amide derivatives as chemokine receptor modulatorsInfo
- Publication number
- TWI340038B TWI340038B TW092120405A TW92120405A TWI340038B TW I340038 B TWI340038 B TW I340038B TW 092120405 A TW092120405 A TW 092120405A TW 92120405 A TW92120405 A TW 92120405A TW I340038 B TWI340038 B TW I340038B
- Authority
- TW
- Taiwan
- Prior art keywords
- pyrimidyl
- chemokine receptor
- receptor modulators
- amide derivatives
- sulphone amide
- Prior art date
Links
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07D239/69—Benzenesulfonamido-pyrimidines
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0217431.6A GB0217431D0 (en) | 2002-07-27 | 2002-07-27 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200406208A TW200406208A (en) | 2004-05-01 |
TWI340038B true TWI340038B (en) | 2011-04-11 |
Family
ID=9941220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW092120405A TWI340038B (en) | 2002-07-27 | 2003-07-25 | Pyrimidyl sulphone amide derivatives as chemokine receptor modulators |
Country Status (26)
Country | Link |
---|---|
US (2) | US7582644B2 (zh) |
EP (1) | EP1527051B1 (zh) |
JP (1) | JP4619782B2 (zh) |
KR (2) | KR101074626B1 (zh) |
CN (1) | CN100345829C (zh) |
AR (1) | AR040700A1 (zh) |
AU (1) | AU2003281684B2 (zh) |
BR (1) | BR0312967A (zh) |
CA (1) | CA2493785C (zh) |
CO (1) | CO5680479A2 (zh) |
EG (1) | EG25893A (zh) |
ES (1) | ES2392965T3 (zh) |
GB (1) | GB0217431D0 (zh) |
HK (1) | HK1076465A1 (zh) |
IL (1) | IL166290A0 (zh) |
IS (1) | IS7697A (zh) |
MX (1) | MXPA05000960A (zh) |
MY (1) | MY139561A (zh) |
NO (1) | NO330531B1 (zh) |
NZ (1) | NZ537914A (zh) |
PL (1) | PL375400A1 (zh) |
RU (1) | RU2342366C2 (zh) |
TW (1) | TWI340038B (zh) |
UA (1) | UA80283C2 (zh) |
WO (1) | WO2004011443A1 (zh) |
ZA (1) | ZA200500791B (zh) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0217431D0 (en) * | 2002-07-27 | 2002-09-04 | Astrazeneca Ab | Novel compounds |
DE60318219T2 (de) | 2002-08-24 | 2009-01-15 | Astrazeneca Ab | PYRIMIDINDERIVATE ALS MODULATOREN DER AKTIVITuT VON CHEMOKINREZEPTOREN |
GB0401269D0 (en) * | 2004-01-21 | 2004-02-25 | Astrazeneca Ab | Compounds |
US7288563B2 (en) | 2004-02-19 | 2007-10-30 | Bristol-Myers Squibb Company | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity |
US7381738B2 (en) | 2004-02-19 | 2008-06-03 | Bristol-Myers Squibb Company | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity |
US7479496B2 (en) | 2004-02-19 | 2009-01-20 | Bristol-Myers Squibb Company | Substituted spiro azabicyclics as modulators of chemokine receptor activity |
US7230022B2 (en) | 2004-02-19 | 2007-06-12 | Bristol-Myers Squibb Company | Substituted fused bicyclic amines as modulators of chemokine receptor activity |
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