BR0212258A - Combinações anti-câncer - Google Patents

Combinações anti-câncer

Info

Publication number
BR0212258A
BR0212258A BR0212258-8A BR0212258A BR0212258A BR 0212258 A BR0212258 A BR 0212258A BR 0212258 A BR0212258 A BR 0212258A BR 0212258 A BR0212258 A BR 0212258A
Authority
BR
Brazil
Prior art keywords
combinations
topoisomerase
inhibitors
cancer
compound
Prior art date
Application number
BR0212258-8A
Other languages
English (en)
Inventor
William Robert Wilson
Bronwyn Gae Siim
Original Assignee
Cancer Rec Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Rec Tech Ltd filed Critical Cancer Rec Tech Ltd
Publication of BR0212258A publication Critical patent/BR0212258A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

"COMBINAçõES ANTI-CâNCER". A presente invenção se refere a combinações sinergísticas do composto ácido 5,6-dimetilxantenona-4-acético (DMXAA) e um composto selecionado entre compostos de platina, alcalóides da vinca, agentes alquilantes, antraciclinas, inibidores da topoisomerase I, anti-metabólitos, e inibidores da topoisomerase II, que possuem atividade anti-tumoral. Mais particularmente, a invenção está voltada para o uso de tais combinações no tratamento do câncer e nas composições farmacêuticas contendo as ditas combinações.
BR0212258-8A 2001-09-03 2002-09-03 Combinações anti-câncer BR0212258A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121285.1A GB0121285D0 (en) 2001-09-03 2001-09-03 Anti-cancer combinations
PCT/GB2002/004025 WO2003020259A2 (en) 2001-09-03 2002-09-03 Combinations of dmxaa and other anti-cancer agents

Publications (1)

Publication Number Publication Date
BR0212258A true BR0212258A (pt) 2004-10-19

Family

ID=9921418

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212258-8A BR0212258A (pt) 2001-09-03 2002-09-03 Combinações anti-câncer

Country Status (23)

Country Link
US (6) US7863322B2 (pt)
EP (3) EP1759694A3 (pt)
JP (3) JP2005509599A (pt)
CN (5) CN1994287A (pt)
AT (1) ATE415963T1 (pt)
AU (1) AU2002324143B2 (pt)
BR (1) BR0212258A (pt)
CA (1) CA2458459A1 (pt)
CY (1) CY1110426T1 (pt)
DE (1) DE60230159D1 (pt)
DK (1) DK1423105T3 (pt)
EA (3) EA200801611A1 (pt)
ES (1) ES2321283T3 (pt)
GB (1) GB0121285D0 (pt)
IL (1) IL160178A0 (pt)
IS (1) IS7144A (pt)
MX (1) MXPA04002004A (pt)
NO (1) NO20040591L (pt)
NZ (5) NZ531045A (pt)
PT (1) PT1423105E (pt)
SI (1) SI1423105T1 (pt)
WO (1) WO2003020259A2 (pt)
ZA (1) ZA200401078B (pt)

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Also Published As

Publication number Publication date
MXPA04002004A (es) 2005-02-17
EP2236134A1 (en) 2010-10-06
US7868040B2 (en) 2011-01-11
DK1423105T3 (da) 2009-03-30
EP1759694A3 (en) 2009-02-18
ZA200401078B (en) 2005-04-15
EP1759694A2 (en) 2007-03-07
WO2003020259A2 (en) 2003-03-13
CN101607087A (zh) 2009-12-23
NZ554093A (en) 2008-07-31
EA010857B1 (ru) 2008-12-30
CA2458459A1 (en) 2003-03-13
US7868039B2 (en) 2011-01-11
CN1994287A (zh) 2007-07-11
US7863322B2 (en) 2011-01-04
DE60230159D1 (de) 2009-01-15
NZ531045A (en) 2006-08-31
PT1423105E (pt) 2009-03-09
EP1423105B1 (en) 2008-12-03
NO20040591L (no) 2004-04-30
WO2003020259A3 (en) 2003-04-17
AU2002324143B2 (en) 2007-09-13
IL160178A0 (en) 2004-07-25
JP2005509599A (ja) 2005-04-14
EA200601118A1 (ru) 2006-12-29
US20080070847A1 (en) 2008-03-20
GB0121285D0 (en) 2001-10-24
US20080070848A1 (en) 2008-03-20
EP1423105A2 (en) 2004-06-02
EA200400370A1 (ru) 2004-08-26
JP2009263371A (ja) 2009-11-12
NZ576925A (en) 2010-07-30
US20070060637A1 (en) 2007-03-15
EA008056B1 (ru) 2007-02-27
CN101596187A (zh) 2009-12-09
EP1423105B9 (en) 2009-08-12
ATE415963T1 (de) 2008-12-15
CN1708296A (zh) 2005-12-14
ES2321283T3 (es) 2009-06-04
JP2010270124A (ja) 2010-12-02
US20040204480A1 (en) 2004-10-14
SI1423105T1 (sl) 2009-08-31
NZ567456A (en) 2009-08-28
NZ546573A (en) 2007-05-31
US7863321B2 (en) 2011-01-04
US7863320B2 (en) 2011-01-04
CN100536840C (zh) 2009-09-09
CY1110426T1 (el) 2015-04-29
EA200801611A1 (ru) 2009-06-30
US20080070886A1 (en) 2008-03-20
IS7144A (is) 2004-02-06
US20080070849A1 (en) 2008-03-20
CN101596186A (zh) 2009-12-09

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