ZA200401078B - Anti-cancer combinations. Anti-cancer combinations. - Google Patents

Anti-cancer combinations. Anti-cancer combinations. Download PDF

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Publication number
ZA200401078B
ZA200401078B ZA200401078A ZA200401078A ZA200401078B ZA 200401078 B ZA200401078 B ZA 200401078B ZA 200401078 A ZA200401078 A ZA 200401078A ZA 200401078 A ZA200401078 A ZA 200401078A ZA 200401078 B ZA200401078 B ZA 200401078B
Authority
ZA
South Africa
Prior art keywords
topoisomerase
inhibitors
compound selected
dmxaa
antimetabolites
Prior art date
Application number
ZA200401078A
Other languages
English (en)
Inventor
William Robert Wilson W Wilson
Bronwyn Gae Siim Bronwyn Siim
Original Assignee
Cancer Res Technology Ltd Canc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Technology Ltd Canc filed Critical Cancer Res Technology Ltd Canc
Publication of ZA200401078B publication Critical patent/ZA200401078B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
ZA200401078A 2001-09-03 2004-02-10 Anti-cancer combinations. Anti-cancer combinations. ZA200401078B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0121285.1A GB0121285D0 (en) 2001-09-03 2001-09-03 Anti-cancer combinations

Publications (1)

Publication Number Publication Date
ZA200401078B true ZA200401078B (en) 2005-04-15

Family

ID=9921418

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200401078A ZA200401078B (en) 2001-09-03 2004-02-10 Anti-cancer combinations. Anti-cancer combinations.

Country Status (23)

Country Link
US (6) US7863322B2 (pt)
EP (3) EP1759694A3 (pt)
JP (3) JP2005509599A (pt)
CN (5) CN101607087A (pt)
AT (1) ATE415963T1 (pt)
AU (1) AU2002324143B2 (pt)
BR (1) BR0212258A (pt)
CA (1) CA2458459A1 (pt)
CY (1) CY1110426T1 (pt)
DE (1) DE60230159D1 (pt)
DK (1) DK1423105T3 (pt)
EA (3) EA010857B1 (pt)
ES (1) ES2321283T3 (pt)
GB (1) GB0121285D0 (pt)
IL (1) IL160178A0 (pt)
IS (1) IS7144A (pt)
MX (1) MXPA04002004A (pt)
NO (1) NO20040591L (pt)
NZ (5) NZ554093A (pt)
PT (1) PT1423105E (pt)
SI (1) SI1423105T1 (pt)
WO (1) WO2003020259A2 (pt)
ZA (1) ZA200401078B (pt)

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Also Published As

Publication number Publication date
CN1708296A (zh) 2005-12-14
US20080070847A1 (en) 2008-03-20
US7863322B2 (en) 2011-01-04
MXPA04002004A (es) 2005-02-17
EP1759694A2 (en) 2007-03-07
EP2236134A1 (en) 2010-10-06
EP1423105B9 (en) 2009-08-12
CN101607087A (zh) 2009-12-23
CN101596186A (zh) 2009-12-09
EA200601118A1 (ru) 2006-12-29
DK1423105T3 (da) 2009-03-30
EP1759694A3 (en) 2009-02-18
EP1423105A2 (en) 2004-06-02
US20080070848A1 (en) 2008-03-20
US20070060637A1 (en) 2007-03-15
EP1423105B1 (en) 2008-12-03
NZ576925A (en) 2010-07-30
CN1994287A (zh) 2007-07-11
IS7144A (is) 2004-02-06
EA010857B1 (ru) 2008-12-30
US7863321B2 (en) 2011-01-04
GB0121285D0 (en) 2001-10-24
AU2002324143B2 (en) 2007-09-13
BR0212258A (pt) 2004-10-19
JP2005509599A (ja) 2005-04-14
NZ546573A (en) 2007-05-31
US20040204480A1 (en) 2004-10-14
EA200400370A1 (ru) 2004-08-26
NO20040591L (no) 2004-04-30
ES2321283T3 (es) 2009-06-04
NZ567456A (en) 2009-08-28
CN100536840C (zh) 2009-09-09
SI1423105T1 (sl) 2009-08-31
US20080070886A1 (en) 2008-03-20
EA200801611A1 (ru) 2009-06-30
US7863320B2 (en) 2011-01-04
DE60230159D1 (de) 2009-01-15
IL160178A0 (en) 2004-07-25
US7868040B2 (en) 2011-01-11
NZ554093A (en) 2008-07-31
CN101596187A (zh) 2009-12-09
NZ531045A (en) 2006-08-31
CA2458459A1 (en) 2003-03-13
WO2003020259A2 (en) 2003-03-13
EA008056B1 (ru) 2007-02-27
ATE415963T1 (de) 2008-12-15
US7868039B2 (en) 2011-01-11
JP2009263371A (ja) 2009-11-12
CY1110426T1 (el) 2015-04-29
PT1423105E (pt) 2009-03-09
WO2003020259A3 (en) 2003-04-17
US20080070849A1 (en) 2008-03-20
JP2010270124A (ja) 2010-12-02

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